Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling by Alexandra Segref, Kavya L. Vakkayil, Tsimafei Padvitski, Qiaochu Li, Virginia Kroef, Jakob Lormann, Lioba Körner, Fabian Finger, Thorsten Hoppe

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The Alpha Variant (B.1.1.7) of SARS-CoV-2 in Children: First Experience from 3544 Nucleic Acid Amplification Tests in a Cohort of Children in Germany by Meike Meyer, Anna Holfter, Esra Ruebsteck, Henning Gruell, Felix Dewald, Robert Walter Koerner, Florian Klein, Clara Lehmann, Christoph Huenseler, Lutz Thorsten Weber

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Case Report: Exome Sequencing Reveals LRBA Deficiency in a Patient With End-Stage Renal Disease by Christina Taylan, Andrea Wenzel, Andrea Wenzel, Florian Erger, Florian Erger, Heike Göbel, Lutz T. Weber, Bodo B. Beck, Bodo B. Beck

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Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit by Julia Hatzold, Filippo Beleggia, Hannah Herzig, Janine Altmüller, Peter Nürnberg, Wilhelm Bloch, Bernd Wollnik, Matthias Hammerschmidt

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Glycyrrhizic Acid Prevents Paclitaxel-Induced Neuropathy via Inhibition of OATP-Mediated Neuronal Uptake by Ines Klein, Jörg Isensee, Martin H. J. Wiesen, Thomas Imhof, Meike K. Wassermann, Carsten Müller, Tim Hucho, Manuel Koch, Helmar C. Lehmann

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Correction to: 3D vs. 4 K Display System - Influence of “State-of-the-art”-Display Technique On Surgical Performance (IDOSP-Study) in minimally invasive surgery: protocol for a ran... by Roger Wahba, Rabi Raj Datta, Andrea Hedergott, Jana Bußhoff, Thomas Bruns, Robert Kleinert, Georg Dieplinger, Hans Fuchs, Caroline Gietzelt, Desdemona Möller, Martin Hellmich, Christiane J. Bruns, Dirk L. Stippel

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Novel noninvasive marker of regression of clear cell renal cell carcinoma (ccRCC) by Barbara Köditz, Melanie von Brandenstein, Manuel Huerta-Arana, Jochen W. U. Fries

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CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia by Dharmesh V. Hirani, Florian Thielen, Siavash Mansouri, Soula Danopoulos, Christina Vohlen, Pinar Haznedar-Karakaya, Jasmine Mohr, Rebecca Wilke, Jaco Selle, Thomas Grosch, Ivana Mizik, Margarete Odenthal, Cristina M. Alvira, Celien Kuiper-Makris, Gloria S. Pryhuber, Christian Pallasch, S. van Koningsbruggen-Rietschel, Denise Al-Alam, Werner Seeger, Rajkumar Savai, Jörg Dötsch, Miguel A. Alejandre Alcazar

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CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated Lymphatic Tissue by Max Augustin, Carola Horn, Meryem Seda Ercanoglu, Ute Sandaradura de Silva, Vincent Bondet, Isabelle Suarez, Seung-Hun Chon, Dirk Nierhoff, Elena Knops, Eva Heger, Carlo Vivaldi, Hartmut Schäfer, Mark Oette, Gerd Fätkenheuer, Florian Klein, Darragh Duffy, Michaela Müller-Trutwin, Clara Lehmann

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Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring by Saida Breuer, Philipp Kasper, Christina Vohlen, Ruth Janoschek, Thorben Hoffmann, Sarah Appel, Elena Müller-Limberger, Andrea Mesaros, Stefan Rose-John, Christoph Garbers, Stefan Müller, Jan-Wilm Lackmann, Esther Mahabir, Jörg Dötsch, Eva Hucklenbruch-Rother, Inga Bae-Gartz

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Clinical application of free-breathing 3D whole heart late gadolinium enhancement cardiovascular magnetic resonance with high isotropic spatial resolution using Compressed SENSE by Lenhard Pennig, Simon Lennartz, Anton Wagner, Marcel Sokolowski, Matej Gajzler, Svenja Ney, Kai Roman Laukamp, Thorsten Persigehl, Alexander Christian Bunck, David Maintz, Kilian Weiss, Claas Philip Naehle, Jonas Doerner

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Personalized, interdisciplinary patient pathway for cross-sector care of multimorbid patients (eliPfad trial): study protocol for a randomized controlled trial by Christoph Heinrich Lindemann, Volker Burst, Linus Alexander Völker, Sebastian Brähler, Dusan Simic, Ingrid Becker, Martin Hellmich, Clarissa Kurscheid, Nadine Scholten, Ruben Krauspe, Kerstin Leibel, Stephanie Stock, Paul Thomas Brinkkoetter

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Predictive value of baseline metabolic tumor volume in early-stage favorable Hodgkin Lymphoma – Data from the prospective, multicenter phase III HD16 trial by Lutz van Heek, Colin Stuka, Helen Kaul, Horst Müller, Jasmin Mettler, Felicitas Hitz, Christian Baues, Michael Fuchs, Peter Borchmann, Andreas Engert, Markus Dietlein, Conrad-Amadeus Voltin, Carsten Kobe

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Fully automated detection and segmentation of intracranial aneurysms in subarachnoid hemorrhage on CTA using deep learning by Rahil Shahzad, Lenhard Pennig, Lukas Goertz, Frank Thiele, Christoph Kabbasch, Marc Schlamann, Boris Krischek, David Maintz, Michael Perkuhn, Jan Borggrefe

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Co-expression patterns of cancer associated fibroblast markers reveal distinct subgroups related to patient survival in oropharyngeal squamous cell carcinoma by Su Ir Lyu, Jannik Johannsen, Jannik Johannsen, Adrian Georg Simon, Karl Knipper, Nora Wuerdemann, Shachi Jenny Sharma, Shachi Jenny Sharma, Martin Thelen, Kevin Karl Hansen, Kevin Karl Hansen, Caroline Fretter, Charlotte Klasen, Charlotte Klasen, Julia Esser, Julia Esser, Malte Christian Suchan, Malte Christian Suchan, Helen Abing, Helen Abing, Philipp Heinrich Zimmermann, Philipp Heinrich Zimmermann, Anne Maria Schultheis, Hans Anton Schloesser, Hans Anton Schloesser, Jens Peter Klussmann, Jens Peter Klussmann, Alexander Quaas, Hans Nikolaus Caspar Eckel, Hans Nikolaus Caspar Eckel

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Correlation of Clinical Fibrillar Layer Detection and Corneal Thickness in Advanced Fuchs Endothelial Corneal Dystrophy by Orlando Özer, Mert Mestanoglu, Antonia Howaldt, Thomas Clahsen, Petra Schiller, Sebastian Siebelmann, Niklas Reinking, Claus Cursiefen, Björn Bachmann, Mario Matthaei

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TIGIT+ NK cells in combination with specific gut microbiota features predict response to checkpoint inhibitor therapy in melanoma patients by Anastasia Tsakmaklis, Fedja Farowski, Rafael Zenner, Till Robin Lesker, Till Strowig, Hans Schlößer, Jonas Lehmann, Michael von Bergwelt-Baildon, Cornelia Mauch, Max Schlaak, Jana Knuever, Viola Schweinsberg, Lucie M. Heinzerling, Maria J. G. T. Vehreschild

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Treatment of rheumatoid arthritis with baricitinib or upadacitinib is associated with reduced scaffold protein NEDD9 levels in CD4+ T cells by Viktoria Golumba‐Nagy, Shuaifeng Yan, Eva Steinbach‐Knödgen, Jan Thiele, Ruth L. Esser, Thomas H. Haak, Anastasia Nikiforov, Anja Meyer, Tamina Seeger‐Nukpezah, David M. Kofler

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Intrauterine Growth Restriction: Need to Improve Diagnostic Accuracy and Evidence for a Key Role of Oxidative Stress in Neonatal and Long-Term Sequelae by Eva Nüsken, Sarah Appel, Leon Saschin, Celien Kuiper-Makris, Laura Oberholz, Charlotte Schömig, Anne Tauscher, Jörg Dötsch, Angela Kribs, Miguel A. Alejandre Alcazar, Kai-Dietrich Nüsken

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EGFR Inhibition Strongly Modulates the Tumour Immune Microenvironment in EGFR-Driven Non-Small-Cell Lung Cancer by Carolin Selenz, Anik Compes, Marieke Nill, Sven Borchmann, Margarete Odenthal, Alexandra Florin, Johannes Brägelmann, Reinhard Büttner, Lydia Meder, Roland T. Ullrich

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