Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility to <i>Mycobacterium abscessus</i> Infections by Fabian Schnitker, Yongjie Liu, Simone Keitsch, Matthias Soddemann, Hedda Luise Verhasselt, Jan Kehrmann, Heike Grassmé, Markus Kamler, Erich Gulbins, Yuqing Wu

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Drivers and barriers of patients’ acceptance of video consultation in cancer care by Angelina Nurtsch, Martin Teufel, Lisa Maria Jahre, André Esber, Raya Rausch, Mitra Tewes, Christoph Schöbel, Stefan Palm, Martin Schuler, Dirk Schadendorf, Eva-Maria Skoda, Alexander Bäuerle

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ECG Changes in Melanoma Patients Undergoing Cancer Therapy—Data from the ECoR Registry by Julia Pohl, Raluca-Ileana Mincu, Simone Maria Mrotzek, Lena Hinrichs, Lars Michel, Elisabeth Livingstone, Lisa Zimmer, Reza Wakili, Dirk Schadendorf, Tienush Rassaf, Matthias Totzeck

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Digital Gene Expression Analysis of Epithelioid and Sarcomatoid Mesothelioma Reveals Differences in Immunogenicity by Luka Brcic, Alexander Mathilakathu, Robert F. H. Walter, Michael Wessolly, Elena Mairinger, Hendrik Beckert, Daniel Kreidt, Julia Steinborn, Thomas Hager, Daniel C. Christoph, Jens Kollmeier, Thomas Mairinger, Jeremias Wohlschlaeger, Kurt Werner Schmid, Sabrina Borchert, Fabian D. Mairinger

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Glycyrrhizin Effectively Inhibits SARS-CoV-2 Replication by Inhibiting the Viral Main Protease by Lukas van de Sand, Maren Bormann, Mira Alt, Leonie Schipper, Christiane Silke Heilingloh, Eike Steinmann, Daniel Todt, Ulf Dittmer, Carina Elsner, Oliver Witzke, Adalbert Krawczyk

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Post-Contrast Acute Kidney Injury after Acute Stroke—Insights from a German Tertiary Care Center by Benedikt Frank, Jordi Kühne Escolà, Leoni Biermann-Ratjen, Anika Hüsing, Yan Li, Philipp Dammann, Ulrich Sure, Christoph Kleinschnitz, Michael Forsting, Martin Köhrmann, Cornelius Deuschl

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Characterization of Temozolomide Resistance Using a Novel Acquired Resistance Model in Glioblastoma Cell Lines by Yuan Zhu, Zhen Chen, Su Na Kim, Chao Gan, Tatsiana Ryl, Michaela Silvia Lesjak, Jan Rodemerk, Rong De Zhong, Karsten Wrede, Philipp Dammann, Ulrich Sure

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Intraoperative Molecular Positron Emission Tomography Imaging for Intraoperative Assessment of Radical Prostatectomy Specimens by Christopher Darr, Pedro Fragoso Costa, Theresa Kahl, Alexandros Moraitis, Jenna Engel, Mulham Al-Nader, Henning Reis, Jens Köllermann, Claudia Kesch, Ulrich Krafft, Tobias Maurer, Daniel Köhler, Susanne Klutmann, Fabian Falkenbach, Jens Kleesiek, Wolfgang P. Fendler, Boris A. Hadaschik, Ken Herrmann

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Cellular and Humoral Immunity against Different SARS-CoV-2 Variants Is Detectable but Reduced in Vaccinated Kidney Transplant Patients by Laura Thümmler, Anja Gäckler, Maren Bormann, Sandra Ciesek, Marek Widera, Hana Rohn, Neslinur Fisenkci, Mona Otte, Mira Alt, Ulf Dittmer, Peter A. Horn, Oliver Witzke, Adalbert Krawczyk, Monika Lindemann

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What Can Laboratory Animal Facility Managers Do to Improve the Welfare of Laboratory Animals and Laboratory Animal Facility Staff? A German Perspective by Birte von der Beck, Andreas Wissmann, Rene H. Tolba, Philip Dammann, Gero Hilken

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The Impact of Increased Maternal sFlt-1/PlGF Ratio on Motor Outcome of Preterm Infants by Lisa Middendorf, Alexandra Gellhaus, Antonella Iannaccone, Angela Köninger, Angela Köninger, Anne-Kathrin Dathe, Anne-Kathrin Dathe, Anne-Kathrin Dathe, Ivo Bendix, Ivo Bendix, Beatrix Reisch, Ursula Felderhoff-Mueser, Ursula Felderhoff-Mueser, Britta Huening, Britta Huening

“…Design/Methods: 88 preterm infants (gestational age ≤ 34 + 0) born between February 2017 and August 2020 at the Department of Obstetrics and Gynecology, University Hospital Essen in Germany, were included, when the following variables were available: maternal sFlt-1/PlGF levels at parturition and general movement assessment of the infant at the corrected age of 3 to 5 months. …”
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Cardiopulmonary Profiling of Athletes with Post-Exertional Malaise after COVID-19 Infection—A Single-Center Experience by Simon Wernhart, Eberhard Weihe, Matthias Totzeck, Bastian Balcer, Tienush Rassaf, Peter Luedike

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Individuals With Weaker Antibody Responses After Booster Immunization Are Prone to Omicron Breakthrough Infections by Birte Möhlendick, Ieva Čiučiulkaitė, Carina Elsner, Olympia E. Anastasiou, Mirko Trilling, Bernd Wagner, Denise Zwanziger, Karl-Heinz Jöckel, Ulf Dittmer, Winfried Siffert

“…Until now, there is no information whether a potential risk of a breakthrough infection can be inferred from the level of antibodies after booster vaccination.MethodsLevels of binding antibodies and neutralization capacity after the first, one and six month after the second, and one month after the third (booster) vaccination against COVID-19 were measured in serum samples from 1391 healthcare workers at the University Hospital Essen. Demographics, vaccination scheme, pre-infection antibody titers and neutralization capacity were compared between individuals with and without breakthrough infections.ResultsThe risk of developing an Omicron breakthrough infection was independent of vaccination scheme, sex, body mass index, smoking status or pre-existing conditions. …”
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CT and DSA for evaluation of spontaneous intracerebral lobar bleedings by Jens-Christian Altenbernd, Jens-Christian Altenbernd, Sebastian Fischer, Wolfram Scharbrodt, Sebastian Schimrigk, Jens Eyding, Hannes Nordmeyer, Christine Wohlert, Nils Dörner, Yan Li, Karsten Wrede, Daniela Pierscianek, Martin Köhrmann, Benedikt Frank, Michael Forsting, Cornelius Deuschl

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The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition by Luca Hegedüs, Elisabeth Livingstone, Ágnes Bánkfalvi, Jan Viehof, Ágnes Enyedi, Ágnes Bilecz, Balázs Győrffy, Marcell Baranyi, Anna-Mária Tőkés, Jeovanis Gil, György Marko-Varga, Klaus G. Griewank, Lisa Zimmer, Renáta Váraljai, Antje Sucker, Anne Zaremba, Dirk Schadendorf, Clemens Aigner, Balázs Hegedüs

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Fully Automated MR Based Virtual Biopsy of Cerebral Gliomas by Johannes Haubold, René Hosch, Vicky Parmar, Martin Glas, Nika Guberina, Onofrio Antonio Catalano, Daniela Pierscianek, Karsten Wrede, Cornelius Deuschl, Michael Forsting, Felix Nensa, Nils Flaschel, Lale Umutlu

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Baseline and average platelet count can predict the outcome of patients with aneurysmal subarachnoid hemorrhage by Christoph Rieß, Marvin Darkwah Oppong, Thiemo-Florin Dinger, Jan Rodemerk, Laurèl Rauschenbach, Meltem Gümüs, Benedikt Frank, Philipp Dammann, Karsten Henning Wrede, Ulrich Sure, Ramazan Jabbarli

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New Prognostic Score (Essen Score) to Predict Postoperative Morbidity after Resection of Lung Metastases by Konstantinos Grapatsas, Fabian Dörr, Hruy Menghesha, Martin Schuler, Viktor Grünwald, Sebastian Bauer, Hartmut H. -J. Schmidt, Stephan Lang, Rainer Kimmig, Stefan Kasper, Natalie Baldes, Servet Bölükbas

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Clinical Course, Myopathology and Challenge of Therapeutic Intervention in Pediatric Patients with Autoimmune-Mediated Necrotizing Myopathy by Adela Della Marina, Marc Pawlitzki, Tobias Ruck, Andreas van Baalen, Nadine Vogt, Bernd Schweiger, Swantje Hertel, Heike Kölbel, Heinz Wiendl, Corinna Preuße, Andreas Roos, Ulrike Schara-Schmidt

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Prevalence of COVID-19 Associated Mucormycosis in a German Tertiary Care Hospital by Ulrike Scharmann, Frank Herbstreit, Nina Kristin Steckel, Jutta Dedy, Jan Buer, Peter-Michael Rath, Hedda Luise Verhasselt

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