Teaching cancer imaging in the era of precision medicine: Looking at the big picture by Christopher N Chin, Ty Subhawong, James Grosso, Jeremy R. Wortman, Lacey J. McIntosh, Ryan Tai, Marta Braschi-Amirfarzan, Patricia Castillo, Francesco Alessandrino

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Sperm Energy Restriction and Recovery (SER) Alters Epigenetic Marks during the First Cell Cycle of Development in Mice by Darya A. Tourzani, Qiangzong Yin, Erica A. Jackson, Oliver J. Rando, Pablo E. Visconti, Maria G. Gervasi

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Precision medicine using whole genome sequencing in a cat identifies a novel COL5A1 variant for classical Ehlers‐Danlos syndrome by Abigail McElroy, Heather Gray‐Edwards, Lyndon M. Coghill, Leslie A. Lyons

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Short-term molecular consequences of chromosome mis-segregation for genome stability by Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, Martina Galli, Marie Dumont, Yonatan Eliezer, René Wardenaar, Marica Rosaria Ippolito, Divya Ramalingam Iyer, Andréa E. Tijhuis, Diana C. J. Spierings, Michael Schubert, Silvia Taglietti, Chiara Soriani, Simon Gemble, Renata Basto, Nick Rhind, Floris Foijer, Uri Ben-David, Daniele Fachinetti, Ylli Doksani, Stefano Santaguida

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Imaging response assessment for oncology: An algorithmic approach by Kathleen Ruchalski, Rohit Dewan, Victor Sai, Lacey J. McIntosh, Marta Braschi-Amirfarzan

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Editorial: Immunogenicity and toxicity of AAV gene therapy by Allison Bradbury, David Markusic, Manish Muhuri, Li Ou, Li Ou

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Evaluating the impact of community health worker certification in Massachusetts: Design, methods, and anticipated results of the Massachusetts community health worker workforce sur... by Victoria M. Nielsen, W. W. Sanouri Ursprung, Glory Song, Gail Hirsch, Theresa Mason, Claire Santarelli, Erica Guimaraes, Erica Marshall, Caitlin G. Allen, Pei-Pei Lei, Diane Brown, Bittie Behl-Chadha

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Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi by Michael J. Rudolph, Simon A. Davis, H. M. Emranul Haque, David D. Weis, David J. Vance, Carol Lyn Piazza, Monir Ejemel, Lisa Cavacini, Yang Wang, M. Lamine Mbow, Robert D. Gilmore, Nicholas J. Mantis

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Early-stage COVID-19 pandemic observations on pulmonary embolism using nationwide multi-institutional data harvesting by Axel Wismüller, Adora M. DSouza, Anas Z. Abidin, M. Ali Vosoughi, Christopher Gange, Isabel O. Cortopassi, Gracijela Bozovic, Alexander A. Bankier, Kiran Batra, Yosef Chodakiewitz, Yin Xi, Christopher T. Whitlow, Janardhana Ponnatapura, Gary J. Wendt, Eric P. Weinberg, Larry Stockmaster, David A. Shrier, Min Chul Shin, Roshan Modi, Hao Steven Lo, Seth Kligerman, Aws Hamid, Lewis D. Hahn, Glenn M. Garcia, Jonathan H. Chung, Talissa Altes, Suhny Abbara, Anna S. Bader

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Editorial: Generation of Functional tissues from human pluripotent stem cells by Dongsheng Guo, Xianming Wang, Ke Huang

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Publisher Correction: Cryo-EM structure of a RAS/RAF recruitment complex by Eunyoung Park, Shaun Rawson, Anna Schmoker, Byeong-Won Kim, Sehee Oh, Kangkang Song, Hyesung Jeon, Michael J. Eck

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Challenges in Use of Practice-based Research Networks for a Medical Device Trial to Detect SARS-CoV-2 by Jeanette M. Daly, Laurel O’Connor, Megan E. Schmidt, Laura K. Ferrara, Kim Parang, Barcey T. Levy

“…Introduction/Objectives: Primary care practice-based research networks (PBRNs) participated in a point of care (POC) device study funded by by the National Institutes of Health and led by the University of Massachusetts Chan Medical School (UMass) to speed the development, validation, and commercialization of POC tests to detect SARS-CoV-2. …”
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Bacteroides Fragilis in the gut microbiomes of Alzheimer’s disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice by Yiyuan Xia, Yifan Xiao, Zhi-Hao Wang, Xia Liu, Ashfaqul M. Alam, John P. Haran, Beth A. McCormick, Xiji Shu, Xiaochuan Wang, Keqiang Ye

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Frailty, cognitive impairment, and depressive symptoms in Chinese older adults: an eight-year multi-trajectory analysis by Yiyang Yuan, Changmin Peng, Jeffrey A. Burr, Kate L. Lapane

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Cranial neurolymphomatosis and its oncologic counterparts: Case series on malignant cranial nerve neuropathies by Bahadar S Srichawla, Abigail Bose, Vincent Kipkorir

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Stepped care versus center-based cardiopulmonary rehabilitation for older frail adults living in rural MA: Design of a feasibility randomized controlled trial by Liana Fraenkel, Quinn Pack, Leslie Drager, Jagruti Patel, Paulette Pontier, Peter K. Lindenauer

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In Vitro Pre-Clinical Evaluation of a Gonococcal Trivalent Candidate Vaccine Identified by Transcriptomics by Shea K. Roe, Brian Felter, Bo Zheng, Sanjay Ram, Lee M. Wetzler, Eric Garges, Tianmou Zhu, Caroline A. Genco, Paola Massari

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Diffusion of medications for opioid use disorder treatment in jail settings: a convergent mixed methods study of jail staff perspectives by Pryce S. Michener, Elizabeth A. Evans, Warren J. Ferguson, Peter D. Friedmann

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Surveillance of gynecologic cancer patients post-COVID-19 vaccine: Are CA-125 levels reliable? by Elizabeth Thayer, Lindsay Walsh, Katherine Leung, Sharmilee Korets

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Anxiety and Depression Among US Nursing Home Residents with Chronic Obstructive Pulmonary Disease by Osundolire S, Goldberg RJ, Lapane KL

“…Seun Osundolire, Robert J Goldberg, Kate L Lapane Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USACorrespondence: Kate L Lapane, Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA, Tel +1 508-688-7618, Email Kate.lapane@umassmed.eduBackground: Chronic obstructive pulmonary disease (COPD) is highly prevalent among nursing home residents; however, few studies have focused on the psychological impact of this clinically significant condition on nursing home residents.Objective: We examine the prevalence of, and factors associated with, anxiety and depression in nursing home residents with COPD.Methods: Using the US 2018 Minimum Dataset (MDS), we conducted a cross-sectional study among 239,615 residents aged ≥ 50 years old in US Medicare/Medicaid certified nursing homes with COPD. …”
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