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    Technical Validation of a Fully Integrated NGS Platform in the Real-World Practice of Italian Referral Institutions by Caterina De Luca, Francesco Pepe, Gianluca Russo, Mariantonia Nacchio, Pasquale Pisapia, Maria Russo, Floriana Conticelli, Lucia Palumbo, Claudia Scimone, Domenico Cozzolino, Gianluca Gragnano, Antonino Iaccarino, Giancarlo Troncone, Umberto Malapelle

    Published 2023-10-01
    “…Methods: A retrospective series of <i>n</i> = 64 samples (<i>n</i> = 32 DNA, <i>n</i> = 32 RNA samples), previously tested using a customized NGS assay (SiRe™ and SiRe fusion), was retrieved from the internal archive of the University of Naples Federico II. Each sample was tested by adopting an Oncomine Precision Assay (OPA), which is able to detect 2769 molecular actionable alterations [hotspot mutations, copy number variations (CNV) and gene fusions] on fully integrated NGS platforms (Genexus, Thermo Fisher Scientific (Waltham, MA, USA). …”
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