Are coiled-coils of dimeric kinesins unwound during their walking on microtubule? by Zhao-Wen Duan, Ping Xie, Wei Li, Peng-Ye Wang

“…Despite the extensive and intensive studies on structures, kinetics, dynamics and walking mechanism of the dimers, whether their coiled-coils are unwound or not during their walking on the microtubule is still an unclear issue. …”
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Colour unwound - disentangling colours for azimuthal asymmetries in Drell-Yan scattering by Daniël Boer, Tom van Daal, Jonathan R. Gaunt, Tomas Kasemets, Piet J. Mulders

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The crossing of two unwound transmembrane regions that is the hallmark of the NhaA structural fold is critical for antiporter activity by Abraham Rimon, Hadar Amartely, Etana Padan

“…Out of the 12 NhaA transmembrane segments (TMs), TMs III–V and X–XII are topologically inverted repeats with unwound TMs IV and XI forming the X shape characterizing the NhaA fold. …”
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Exposure of unwounded plants to chemical cues associated with herbivores leads to exposure-dependent changes in subsequent herbivore attack. by John L Orrock

“…Although chemical predator cues often lead to changes in the anti-predator behavior of animal prey, it is not clear whether non-volatile herbivore kairomones (i.e. incidental chemical cues produced by herbivore movement or metabolism but not produced by an attack) trigger the induction of defense in plants prior to attack. I found that unwounded plants (Brassica nigra) that were regularly exposed to kairomones from snails (mucus and feces produced during movement of Helix aspersa) subsequently experienced reduced rates of attack by snails, unlike unwounded plants that received only one initial early exposure to snail kairomones. …”
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The DnaA AAA+ Domain His136 Residue Directs DnaB Replicative Helicase to the Unwound Region of the Replication Origin, oriC by Yukari Sakiyama, Masahiro Nishimura, Chihiro Hayashi, Yusuke Akama, Shogo Ozaki, Tsutomu Katayama

“…However, mechanisms of DnaB loading to the unwound oriC remain largely elusive. In this study, we determined that His136 of DnaA domain III has an important role in loading of DnaB helicases onto the unwound oriC. …”
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The supersymmetric Neveu-Schwarz branes of non-relativistic string theory by E. A. Bergshoeff, J. Lahnsteiner, L. Romano, J. Rosseel

“…Correspondingly, we refer to these non-Lorentzian backgrounds as winding string and unwound string solution. Whereas the winding string is part of the on-shell spectrum of non-relativistic string theory, the unwound string only makes sense off-shell where it mediates the instantaneous gravitational force. …”
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A FULLERENE WITHOUT A SPIRAL by Manolopoulos, D, Fowler, P

“…The spiral conjecture for fullerenes, namely that the surface of every fullerene may be unwound in at least one continuous spiral strip of edge-sharing five- and six-membered rings, is shown to be strictly false. …”

Dynamics of Polymer Membrane Swelling in Aqueous Suspension of Amino-Acids with Different Isotopic Composition; Photoluminescence Spectroscopy Experiments by Nikolai F. Bunkin, Polina N. Bolotskova, Elena V. Bondarchuk, Valery G. Gryaznov, Valeriy A. Kozlov, Maria A. Okuneva, Oleg V. Ovchinnikov, Nikita V. Penkov, Oleg P. Smoliy, Igor F. Turkanov

“…It is of interest to clarify the role of unwound fibers in the interaction of amino-acids with the polymer membrane surface. …”
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Multibody dynamics simulation and experimental verification for unwinding behavior of bobbin yarn by Hidetoshi TAKEUCHI, Nobuyuki SHIMIZU, Tsuyoshi INOUE, Kentaro TAKAGI, Masahiko AKI

“…In this paper, only the part of the yarn between the unwound point and the pulling point is considered in order to reduce the calculation load. …”
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Preparing to unwind by Jin Chuan Zhou, Alessandro Costa

“…A combination of protein crystallography and biochemistry has revealed how a ring-shaped helicase might trap a single DNA strand as the double helix melts, and before it is unwound.…”
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Nafion: A Flexible Template for Selective Structuring by Nikolai F. Bunkin, Polina N. Bolotskova, Sergey V. Gudkov, Minh T. Khuong, Valeriy A. Kozlov, Svetlana L. Timchenko, Valeriy V. Voronov, Yulia V. Novakovskaya

“…As was obtained in experiments with X-ray diffractometry, the unwound polymer fibers predetermine syngony of crystals, for which the unit cell is either a rectangular parallelepiped (monoclinic system) or an oblique parallelepiped (triclinic system). …”
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Self-Attractive Semiflexible Polymers under an External Force Field by Antonio Lamura

“…Under the external field at small rigidities, the initial close-packed chain is continuously unwound by the force before being completely elongated. …”
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Structure of a RecT/Redβ family recombinase in complex with a duplex intermediate of DNA annealing by Brian J. Caldwell, Andrew S. Norris, Caroline F. Karbowski, Alyssa M. Wiegand, Vicki H. Wysocki, Charles E. Bell

“…Here the authors reveal an intermediate of annealing in which a duplex DNA is bound in an unusual conformation that is highly extended and unwound for the ssDNA binding protein Redβ from bacteriophage λ.…”
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Denaturation of dsDNA immobilised at a negatively charged gold electrode is not caused by electrostatic repulsion by Johnson, R, Gale, N, Richardson, J, Brown, T, Bartlett, P

“…Double-stranded DNA immobilised through a thiol anchor at a gold electrode surface can be unwound and denatured by applying a negative potential. …”

Transcription initiation at a consensus bacterial promoter proceeds via a 'bind-unwind-load-and-lock' mechanism by Mazumder, A, Ebright, RH, Kapanidis, A

“…We find that the RNAP clamp is closed during promoter binding, remains closed during promoter unwinding, and then closes further, locking the unwound DNA in the RNAP active-centre cleft. Our work defines a new, 'bind-unwind-load-and-lock' model for the series of conformational changes occurring during promoter unwinding at a consensus bacterial promoter and provides the tools needed to examine the process in other organisms and at other promoters.…”

Molecular mechanism of type I collagen homotrimer resistance to mammalian collagenases. by Han, S, Makareeva, E, Kuznetsova, N, DeRidder, A, Sutter, M, Losert, W, Phillips, C, Visse, R, Nagase, H, Leikin, S

“…Similar MMP-1 binding to the two isoforms and similar cleavage efficiency of unwound alpha1(I) and alpha2(I) chains suggested increased stability and less efficient unwinding of the homotrimer triple helix at the collagenase cleavage site. …”

Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain. by Stura, E, Visse, R, Cuniasse, P, Dive, V, Nagase, H

“…For collagenase to cleave triple helical collagens, the triple helical structure has to be locally unwound before hydrolysis, but this process is not well understood. …”

CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3. by Westra, E, van Erp, P, Künne, T, Wong, S, Staals, R, Seegers, C, Bollen, S, Jore, M, Semenova, E, Severinov, K, de Vos, WM, Dame, RT, de Vries, R, Brouns, S, van der Oost, J

“…The target is then progressively unwound and cleaved by the joint ATP-dependent helicase activity and Mg(2+)-dependent HD-nuclease activity of Cas3, leading to complete target DNA degradation and invader neutralization.…”

WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork. by Sharma, S, Otterlei, M, Sommers, J, Driscoll, H, Dianov, G, Kao, H, Bambara, R, Brosh, R

“…Biochemical analyses demonstrate that WRN helicase unwinds the chicken-foot HJ intermediate associated with a regressed replication fork and stimulates FEN-1 to cleave the unwound product in a structure-dependent manner. These results provide evidence for an interaction between WRN and FEN-1 in vivo and suggest that these proteins function together to process DNA structures associated with the replication fork.…”

Spoofing and price manipulation in order-driven markets by Cartea, Á, Jaimungal, S, Wang, Y

“…Spoofing increases the PnL because (i) the investor employs fewer MOs to draw the inventory to zero and benefits from roundtrip trades, which stem from spoof buy LOs that are ‘inadvertently’ filled and subsequently unwound with sell LOs; and (ii) the midprice trends upward when the book is buy-heavy; therefore the spoofer sells the asset at better prices.…”