EFFECTS OF HOMOLOGOUS AND HETEROLOGOUS BOOSTER VACCINATIONS OF THE INACTIVATED DUAL-ADJUVANTED VACCINE VLA2001 AGAINST COVID-19 INCLUDING VARIANTS OF CONCERN: A PHASE 3 RANDOMIZED... by N. Wressnigg, C. Taucher, S. Eder-Lingelbach, B. Querton, M. Krammer, A. Lilja, R. Hochreiter, M. Hoffmann, S. Pöhlmann, J.-C. Jaramillo

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Evaluation of Heterologous Effects of Travel Vaccines in Colorectal Cancer: A Database Study and a Cautionary Tale by Eva Herweijer, Klaus Schwamborn, Kaatje Bollaerts, Adrian Spillmann, Tom Cattaert, Thomas Verstraeten, Janet Hoogstraate

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Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins by Alexander Pralow, Alexander Nikolay, Arnaud Leon, Yvonne Genzel, Erdmann Rapp, Udo Reichl

“…The virus was propagated with high yield in an embryo-derived stem cell line (EB66, Valneva SE), and concentrated by g-force step-gradient centrifugation. …”
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CovFrameNet: An Enhanced Deep Learning Framework for COVID-19 Detection by Olaide Nathaniel Oyelade, Absalom El-Shamir Ezugwu, Haruna Chiroma

“…Research into the production of relevant vaccines is progressively being advanced with the development of the Pfizer and BioNTech, AstraZeneca, Moderna, Sputnik V, Janssen, Sinopharm, Valneva, Novavax and Sanofi Pasteur vaccines. There is, however, a need for a computational intelligence solution approach to mediate the process of facilitating quick detection of the disease. …”
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Antiviral drugs and vaccines currently used for COVID-19 by Łukasz Dobrek

“…The manuscript is a narrative review describing the pathophysiology of SARS-CoV-2 infection and COVID-19 symptomatology and briefly characterizing both the vaccines against COVID-19 currently registered by the European Medicines Agency (EMA) and/or the US Food and Drug Administration (FDA) (company products: BioNTech and Pfizer, Moderna Biotech Spain S.L., Janssen-Cilag International NV, Novavax CZ, a.s., AstraZeneca AB, Sanofi Pasteur, Valneva Austria GmbH and HIPRA Human Health S.L.U.). …”
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Prospective incidence epidemiology study protocol: conducting active surveillance to assess the burden of Lyme disease (BOLD) in primary care practices in endemic areas of six Euro... by Mendwas Dzingina, James H Stark, Bradford D Gessner, Kristen E Allen, Elizabeth Begier, Andreas Pilz, Alexandra Loew-Baselli, Lisa R Harper, Molly Bowdery, Kate Halsby, Nicole Bézay, Ben Parslow

“…This study will inform the phase III efficacy study for Pfizer and Valneva’s investigational Lyme disease vaccine, VLA15. …”
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Whole blood RNA signatures in tuberculosis patients receiving H56:IC31 vaccine as adjunctive therapy by Noelia Alonso-Rodríguez, Eleonora Vianello, Suzanne van Veen, Synne Jenum, Kristian Tonby, Kristian Tonby, Rosalie van Riessen, Xiaoran Lai, Rasmus Mortensen, Tom H. M. Ottenhoff, Anne Ma Dyrhol-Riise, Anne Ma Dyrhol-Riise

“…The H56:IC31 group received 5 micrograms of the H56:IC31 vaccine (Statens Serum Institut; SSI, Valneva Austria GmbH) intramuscularly at day 84 and day 140. …”
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Infection by Streptococcus pneumoniae in children with or without radiologically confirmed pneumonia by Dafne C. Andrade, Igor C. Borges, Ana Luísa Vilas‐Boas, Maria S.H. Fontoura, César A. Araújo‐Neto, Sandra C. Andrade, Rosa V. Brim, Andreas Meinke, Aldina Barral, Olli Ruuskanen, Helena Käyhty, Cristiana M. Nascimento‐Carvalho

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Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice by Audur Anna Aradottir Pind, Audur Anna Aradottir Pind, Magdalena Dubik, Magdalena Dubik, Sigrun Thorsdottir, Andreas Meinke, Ali M. Harandi, Ali M. Harandi, Jan Holmgren, Jan Holmgren, Giuseppe Del Giudice, Ingileif Jonsdottir, Ingileif Jonsdottir, Ingileif Jonsdottir, Stefania P. Bjarnarson, Stefania P. Bjarnarson

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A comparative study of adjuvants effects on neonatal plasma cell survival niche in bone marrow and persistence of humoral immune responses by Audur Anna Aradottir Pind, Audur Anna Aradottir Pind, Sigrun Thorsdottir, Gudbjorg Julia Magnusdottir, Gudbjorg Julia Magnusdottir, Andreas Meinke, Giuseppe Del Giudice, Ingileif Jonsdottir, Ingileif Jonsdottir, Stefania P. Bjarnarson, Stefania P. Bjarnarson

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Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan by Maria Vono, Christiane Sigrid Eberhardt, Christiane Sigrid Eberhardt, Elodie Mohr, Floriane Auderset, Dennis Christensen, Mirco Schmolke, Rhea Coler, Andreas Meinke, Peter Andersen, Paul-Henri Lambert, Beatris Mastelic-Gavillet, Claire-Anne Siegrist, Claire-Anne Siegrist

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Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients—a randomized clinical trial by Christopher Adlbrecht, Raphael Wurm, Pieter Depuydt, Herbert Spapen, Jose A. Lorente, Thomas Staudinger, Jacques Creteur, Christian Zauner, Andreas Meier-Hellmann, Philipp Eller, Margot Vander Laenen, Zsolt Molnár, István Várkonyi, Bernhard Schaaf, Mária Héjja, Vladimír Šrámek, Hauke Schneider, Niranjan Kanesa-thasan, Susanne Eder-Lingelbach, Anton Klingler, Katrin Dubischar, Nina Wressnigg, Jordi Rello

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Immunogenicity and efficacy of VLA2001 vaccine against SARS-CoV-2 infection in male cynomolgus macaques by Mathilde Galhaut, Urban Lundberg, Romain Marlin, Robert Schlegl, Stefan Seidel, Ursula Bartuschka, Jürgen Heindl-Wruss, Francis Relouzat, Sébastien Langlois, Nathalie Dereuddre-Bosquet, Julie Morin, Maxence Galpin-Lebreau, Anne-Sophie Gallouët, Wesley Gros, Thibaut Naninck, Quentin Pascal, Catherine Chapon, Karine Mouchain, Guillaume Fichet, Julien Lemaitre, Mariangela Cavarelli, Vanessa Contreras, Nicolas Legrand, Andreas Meinke, Roger Le Grand

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Cholera toxin and O-specific polysaccharide immune responses after oral cholera vaccination with Dukoral in different age groups of Bangladeshi participants by Pinki Dash, Al Hakim, Aklima Akter, Hasan Al Banna, M. Hasanul Kaisar, Amena Aktar, Sultana Rownok Jahan, Jannatul Ferdous, Salima Raiyan Basher, Mohammad Kamruzzaman, Fahima Chowdhury, Afroza Akter, Imam Tauheed, Ana A. Weil, Richelle C. Charles, Stephen B. Calderwood, Edward T. Ryan, Regina C. LaRocque, Jason B. Harris, Taufiqur Rahman Bhuiyan, Firdausi Qadri

“…There are limited data comparing anti-O-specific polysaccharide (OSP) and anti-cholera toxin-specific immune responses following oral whole-cell with cholera toxin B-subunit (WC-rBS) vaccine (Dukoral, Valneva) administration in different age groups. An understanding of the differences is relevant because young children are less well protected by oral cholera vaccines than older children and adults. …”
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Infection by Streptococcus pneumoniae in children with or without radiologically confirmed pneumonia by Dafne C. Andrade, Igor C. Borges, Ana Luísa Vilas-Boas, Maria S.H. Fontoura, César A. Araújo-Neto, Sandra C. Andrade, Rosa V. Brim, Andreas Meinke, Aldina Barral, Olli Ruuskanen, Helena Käyhty, Cristiana M. Nascimento-Carvalho

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