Identification of metabolic biomarkers associated with nonalcoholic fatty liver disease by Hua Jiang, Yang Hu, Zhibo Zhang, Xujia Chen, Jianpeng Gao

“…Next, 18 MR-DEGs were identified using the Venn diagram. Subsequently, four genes, including AMDHD1, FMO1, LPL, and P4HA1, were identified using machine learning algorithms. …”
Get full text

Perturbations of Metabolomic Profiling of Spleen From Rats Infected With Clonorchis sinensis Determined by LC-MS/MS Method by Xiaoli Zhang, Xinyi Hu, Rui Chen, Beibei Sun, Yannan Gao, Shanshan Duan, Liyan Liu, Su Han

“…There were 38 significantly different metabolites shared in the two infected groups compared with the control group through the Venn diagram. The metabolic pathways analysis revealed that pyrimidine metabolism, aminoacyl-tRNA biosynthesis, purine metabolism and phenylalanine, tyrosine and tryptophan biosynthesis were significantly enriched in differential metabolites, which was speculated to be related to the disease progression of clonorchiasis. …”
Get full text

Comprehensive analysis of anoikis-related genes in diagnosis osteoarthritis: based on machine learning and single-cell RNA sequencing data by Jun-Song Zhang, Run-Sang Pan, Guo-Lu Li, Jian-Xiang Teng, Hong-Bo Zhao, Chang-Hua Zhou, Ji-Sheng Zhu, Hao Zheng, Xiao-Bin Tian

“…The intersection genes of the differential anoikis-related genes (DEARGs) were identified using a Venn diagram. Infiltration analyses were used to identify and study the differentially expressed genes (DEGs). …”
Get full text

Identification and Verification of Diagnostic Biomarkers for Glomerular Injury in Diabetic Nephropathy Based on Machine Learning Algorithms by Hongdong Han, Yanrong Chen, Hao Yang, Wei Cheng, Sijing Zhang, Yunting Liu, Qiuhong Liu, Dongfang Liu, Gangyi Yang, Ke Li

“…By using machine learning algorithms (LASSO, RF, and SVM-RFE) and the Venn diagram, two overlapping genes (PRKAR2B and TGFBI) were finally determined as potential biomarkers, which were further validated in external testing datasets and the HFD/STZ-induced mouse models. …”
Get full text

Revealing genes associated with vitellogenesis in the liver of the zebrafish (<it>Danio rerio</it>) by transcriptome profiling by Hyslop Terry, Fortina Paolo, Gutman Ellen, Pekarski Irena, Levi Liraz, Biran Jakob, Levavi-Sivan Berta, Lubzens Esther

“…</p> <p>Results</p> <p>Genes associated with vitellogenesis were revealed by the following paired t-tests (SAM) comparisons: a) two-month old vitellogenic (Vit2) females were compared with non-vitellogenic (NV) females, showing 825 differentially expressed transcripts during early stages of vitellogenesis, b) four-month old vitellogenic (Vit4) females were compared with NV females, showing 1,046 differentially expressed transcripts during vitellogenesis and c) E2-treated males were compared with control males, showing 1,828 differentially expressed transcripts regulated by E2. A Venn diagram revealed 822 common transcripts in the three groups, indicating that these transcripts were involved in vitellogenesis and putatively regulated by E2. …”
Get full text

Exploring SARS-CoV2 host-pathogen interactions and associated fungal infections cross-talk: Screening of targets and understanding pathogenesis by Abdul Arif Khan, Sudhir K. Jain, Mahendra Rai, Samiran Panda

“…We screened host targets involved in COVID-19-associated opportunistic fungal infections, in addition to host-pathogen interaction data of SARS-CoV2 from well-known and widely used biological databases. Venn diagram was prepared to screen common host targets involved in studied COVID-19-associated fungal infections. …”
Get full text

PKMYT1 as a Potential Target to Improve the Radiosensitivity of Lung Adenocarcinoma by Huan-ping Long, Jia-qing Liu, Yang-yang Yu, Qiao Qiao, Guang Li

“…ObjectiveThis article is dedicated to finding important genes related to the prognosis of lung adenocarcinoma (LUAD), looking for a new gene that may affect tumor radiosensitivity, and conducting basic experiments to verify the relationship between this gene and the radiosensitivity of LUAD.MethodsThe gene expression profiles GSE32863, GSE33532, and GSE43458 were obtained from NCBI-GEO. GEO2R and a Venn diagram were used to identify upregulated genes. …”
Get full text

Relationship of Soil Microbiota to Seed Kernel Metabolism in Camellia oleifera Under Mulched by Honglian Ye, Honglian Ye, Yue Wen, Zhigang Chen, Taikui Zhang, Shengxing Li, Menglong Guan, Yunqi Zhang, Shuchai Su

“…A total of 1,106 OTUs were detected by using 16S rRNA, and Venn diagram showed that there were 106 unique OTUs in control and 103 OTUs in the treatment, respectively. …”
Get full text

Whole transcriptome analysis of breast tumors during neoadjuvant chemotherapy: association with response to preoperative chemotherapy by M. K. Ibragimova, M. M. Tsyganov, N. V. Litviakov

“…Comparison of preand post-treatment expression profiles demonstrated 680 differentially expressed genes in patients with complete and partial response and 3240 differentially expressed genes in patients with stable or progressive disease. Venn diagram showed that patients with and without objective response to neoadjuvant chemotherapy shared 105 differentially expressed genes.Conclusion. …”
Get full text

Study of the Active Components and Molecular Mechanism of Tripterygium wilfordii in the Treatment of Diabetic Nephropathy by Lin Wang, Zheyi Wang, Zhihua Yang, Kang Yang, Hongtao Yang

“…Second, the target set of DN was obtained through the disease database, and the potential targets of TW in the treatment of DN were screened through a Venn diagram. A protein interaction network diagram (PPI) was constructed with the help of the String platform and Cytoscape 3.7.2. …”
Get full text

Identification of Hub Genes in Type 2 Diabetes Mellitus Using Bioinformatics Analysis by Lin Y, Li J, Wu D, Wang F, Fang Z, Shen G

“…DEGs between T2DM islet and normal islet were picked out by the GEO2R tool and Venn diagram software. Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed using the Database for Annotation, Visualization, and Integrated Discovery (DAVID) to identify the pathways and functional annotation of DEGs. …”
Get full text

Monitoring Changes in the Volatile Profile of Ecuadorian Cocoa during Different Steps in Traditional On-Farm Processing by Cyntia Yadira Erazo Solorzano, Diego Armando Tuárez García, Carlos Edison Zambrano, José Manuel Moreno-Rojas, Raquel Rodríguez Solana

“…According to the chemometric and Venn diagram analyses, ETT-103 was an interestingly high-aromatic-quality variety for cocoa gourmet preparations. …”
Get full text

Transcriptomic Analysis Reveals Genes Associated with the Regulation of Peach Fruit Softening and Senescence during Storage by Shaolei Guo, Ruijuan Ma, Jianlan Xu, Binbin Zhang, Mingliang Yu, Zhihong Gao

“…The mitogen-activated protein kinase signaling pathway-plant and plant hormone signal transduction pathways were associated with peach fruit softening and senescence according to the Venn diagram analysis and weighted gene co-expression network analysis. …”
Get full text

Bioinformatics Analysis of Common Differential Genes of Viral Myocarditis and Dilated Cardiomyopathy: Screening for Potential Pharmacological Compounds by Junyi Zhang, Mingzhu Xu, Tan Chen, Yafeng Zhou

“…The aim of this study was to identify key genes in the progression of VMC to DCM, so as to find potential therapeutic drugs and provide insights for future research. (2) Methods: Differential expression analysis of GSE4172 and GSE17800 from the Gene Expression Omnibus (GEO) database was performed using GEO2R, which contained genome-wide analysis of myocardial biopsies from VMC and DCM, respectively. We used the Venn diagram analysis to screen the common differentially expressed genes (DEGs). …”
Get full text

Long-term administration of whey alters atrophy, gene expression profiles and dysfunction of salivary glands in elderly rats by Tomasz D. Pieczonka, Aneta M. Bragiel, Hideaki Horikawa, Kana Fukuta, Masami Yoshioka, Yasuko Ishikawa

“…The expression levels of genes associated with salivary proteins and tissue repair were significantly increased, while those associated with lipid metabolism were decreased. Venn diagram analysis revealed that expressions of 13 genes, including Tcfap2b and Abpa, were induced significantly by whey-drinking. …”
Get full text

Bioconversion of coal to methane by microbial communities from soil and from an opencast mine in the Xilingol grassland of northeast China by Bobo Wang, Yanfen Wang, Xiaoyong Cui, Yiming Zhang, Zhisheng Yu

“…In soil, hydrogenotrophic Methanobacterium was the dominant methanogen, and this methanogen, along with acetoclastic Methanosarcina and methylotrophic Methanomassiliicoccus, was detected in coal. Network-like Venn diagram showed that an average of 28.7% of microbial communities in the samples belonged to shared genera, indicating that there is considerable microbial overlap between coal and soil samples. …”
Get full text

A genome-wide comparison of mesenchymal stem cells derived from human placenta and umbilical cord by Sen-Wen Teng, Yu-Shu Lo, Wei-Ting Liu, Yogi Hsuan, Willie Lin

“…Results: According to the DEGs of umbilical cord and placenta, we used the Venn diagram to evaluate the consistence and specific genes. …”
Get full text

Network Pharmacology-Based Study to Uncover Potential Pharmacological Mechanisms of Korean Thistle (<i>Cirsium japonicum</i> var. <i>maackii</i> (Maxim.) Matsum.) Flower against Ca... by Ki-Kwang Oh, Md. Adnan, Dong-Ha Cho

“…Next, target(s) associated with the obtained bioactives or cancer-related targets were retrieved by public databases, and the Venn diagram selected the overlapping targets. The networks between overlapping targets and bioactives were visualized, constructed, and analyzed by RPackage. …”
Get full text

UBE2C affects breast cancer proliferation through the AKT/mTOR signaling pathway by Zi-Nan Lu, Jia Song, Tong-Hui Sun, Gang Sun, Yan-Jie Yin, Xiu-Yuan Hao

“…Then differentially expressed genes (DEGs) were identified using Venn diagram analysis. By using DEGs, we conducted the following analyses including Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), protein–protein interaction (PPI), and survival analysis, and then validated the function of the hub gene UBE2C using quantitative reverse transcription-polymerase chain reaction (RT-qPCR), cell counting kit-8 (CCK-8) assay, transwell assay, and Western blot assay. …”
Get full text

Characterization of a de novo assembled transcriptome of the Common Blackbird (Turdus merula) by Sven Koglin, Daronja Trense, Michael Wink, Hedwig Sauer-Gürth, Dieter Thomas Tietze

“…The draft transcriptome and the three single tissues were compared by their BLAST hits with the package VennDiagram in R. Results Following the annotation against protein databases, we found evidence for 15,580 genes in the transcriptome (all well characterized hits after annotation). …”
Get full text