Droplet Digital PCR Assay for MYD88L265P: Clinical Applications in Waldenström Macroglobulinemia by Mariella Lo Schirico, Martina Ferrante, Irene Dogliotti, Alberto Zamò, Bruno Ferrero, Davide Bertuzzo, Giulia Benevolo, Paola Omedè, Federica Cavallo, Marco Ladetto, Mario Boccadoro, Daniela Drandi, Simone Ferrero

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Diagnostic Next-generation Sequencing Frequently Fails to Detect MYD88L265P in Waldenström Macroglobulinemia by Amanda Kofides, Zachary R. Hunter, Lian Xu, Nicholas Tsakmaklis, Maria G. Demos, Manit Munshi, Xia Liu, Maria Luisa Guerrera, Carly R. Leventoff, Timothy P. White, Catherine A. Flynn, Kirsten Meid, Christopher J. Patterson, Guang Yang, Andrew R. Branagan, Shayna Sarosiek, Jorge J. Castillo, Steven P. Treon, Joshua N. Gustine

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P1159: A MULTICENTER, INTERNATIONAL COLLABORATIVE STUDY EVALUATING FRONTLINE THERAPY WITH BENDAMUSTINE RITUXIMAB FOR WALDENSTRÖM MACROGLOBULINEMIA by S. Zanwar, J. Abeykoon, J. Castillo, E. Durot, E. Kastritis, E. Uppal, P. Morel, R. Tawfiq, L. Montes, J. Paludo, S. Sarosiek, S. Kumar, O. Ogunbiyi, P. Cornillet-Lefebvre, R. Kyle, A. Delmer, M. Gertz, M. Dimopoulos, S. Ansell, S. Treon, S. D’Sa, P. Kapoor

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P941: SERUM CXCL13 LEVEL AIDS IN DISEASE REMISSION EVALUATION AND PROGNOSIS PREDICTION IN WALDENSTRÖM MACROGLOBULINEMIA by Jia Chen, Ming-Nan Jia, Hao Cai, Ze-Peng LI, Jian LI, Dao-Bin Zhou, Xin-Xin Cao

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Recurrent upper gastro-intestinal bleeding, duodenal and gastric ulcer and peliosis hepatis in a patient with Waldenstrom's macroglobulinemia. by A. Ginestal-Cruz, J. Pinto Correia, Amélia Batista, Anabela Cardoso, Estela Monteiro

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PB2081: TREATMENT PERSISTENCE AND ADHERENCE TO IBRUTINIB IN PATIENTS WITH WALDENSTRÖM MACROGLOBULINEMIA: A GERMAN CLAIMS DATA ANALYSIS by C. Buske, G. Hess, N. Bahar, K. Yang, B. Tang, A. Imhof, K. Vinz, E. Herweijer, M. Herold

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Invasive Cutaneous Candidiasis, Autoimmune Hemolytic Anemia and Pancytopenia: A Challenging Scenario for Waldenström Macroglobulinemia in an Elderly Patient by Juan Carlos Caballero, Elham Askari, Nerea Carrasco, Miguel Angel Piris, Begoña Perez de Camino, Laura Pardo, Javier Cornago, Jose Luis Lopez-Lorenzo, Pilar Llamas, Laura Solan

Subjects: “…Waldenström macroglobulinemia…”
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Clonal Relationship and Mutation Analysis in Lymphoplasmacytic Lymphoma/Waldenström Macroglobulinemia Associated With Diffuse Large B-cell Lymphoma by Madeleine R. Berendsen, Diede A.G. van Bladel, Eva Hesius, Cristina Berganza Irusquieta, Jos Rijntjes, Annemiek B. van Spriel, Ellen van der Spek, Johannes F.M. Pruijt, Leonie I. Kroeze, Konnie M. Hebeda, Sandra Croockewit, Wendy B.C. Stevens, J Han J.M. van Krieken, Patricia J.T.A. Groenen, Michiel van den Brand, Blanca Scheijen

“…Patients with lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) occasionally develop diffuse large B-cell lymphoma (DLBCL). …”
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Single‐cell analysis of MYD88L265P and MYD88WT Waldenström macroglobulinemia patients by Tina Bagratuni, Foteini Aktypi, Ourania Theologi, Maria Sakkou, Kleio Maria Verrou, Nefeli Mavrianou‐Koutsoukou, Dimitrios Patseas, Christine Liacos, Stamatia Skourti, Alexandra Papadimou, Kostantina Taouxi, Foteini Theodorakakou, Georgios Kollias, Petros Sfikakis, Evangelos Terpos, Meletios A. Dimopoulos, Efstathios Kastritis

“…Abstract Waldenström macroglobulinemia (WM) is characterized by the expansion of clonal lymphoplasmacytic cells; the MYD88L265P somatic mutation is found in >90% of patients, but malignant B cells may still display intra‐clonal heterogeneity. …”
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Zanubrutinib in patients with treatment‐naïve or relapsed/refractory Waldenström macroglobulinemia: An expanded‐access study of 50 patients in the United States by Jorge J Castillo, Edwin C Kingsley, Mohit Narang, Habte A Yimer, Constantin A Dasanu, Jason M Melear, Morton Coleman, Charles M Farber, Jonah Shulman, Emily H Mantovani, Xiaowei Zhang, Aileen Cohen, Jane Huang

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Bing‐Neel syndrome by Katelynn Davis, William H. Sharfman, Ivo M. B. Francischetti

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Bing-Neel Syndrome, a Rare Presentation of Waldenström Macroglobulinemia—A Multicenter Report by the Polish Lymphoma Research Group by Joanna Drozd-Sokołowska, Anna Waszczuk-Gajda, Magdalena Witkowska, Elżbieta Sienkiewicz, Anna Kopińska, Agnieszka Kołkowska-Leśniak, Joanna Barankiewicz, Monika Długosz-Danecka, Piotr Smolewski, Grzegorz Helbig, Ewa Lech-Marańda, Wojciech Jurczak, Przemysław Biecek, Sebastian Giebel, Wiesław Wiktor-Jędrzejczak, Grzegorz Basak

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Case report: Circulating tumor DNA technology displays temporal and spatial heterogeneity in Waldenström macroglobulinemia during treatment with BTK inhibitors by Jingjing Zhu, Xinyu Zhu, Fengyang Xie, Yi Ding, Huina Lu, Yan Dong, Ping Li, Jianfei Fu, Aibin Liang, Yu Zeng, Bing Xiu

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Waldenström Macroglobulinemia in Very Elderly (≥75-year-old) Patients: A 33-year-retrospective Cohort Study in an Italian University Hospital by Nicolò Danesin, Mariella Lo Schirico, Greta Scapinello, Angela Grassi, Marcello Riva, Tamara Berno, Antonio Branca, Andrea Visentin, Marco Carraro, Laura Pavan, Sabrina Manni, Laura Bonaldi, Annalisa Martines, Roberta Bertorelle, Fabrizio Vianello, Carmela Gurrieri, Chiara Briani, Renato Zambello, Livio Trentin, Francesco Piazza

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A recurrent activating missense mutation in Waldenström macroglobulinemia affects the DNA binding of the ETS transcription factor SPI1 and enhances proliferation by Roos-Weil, D, Decaudin, C, Armand, M, Della-Valle, V, Diop, M, Ghamlouch, H, Ropars, V, Herate, C, Lara, D, Durot, E, Haddad, R, Mylonas, E, Damm, F, Pflumio, F, Stoilova, B, Metzner, M, Elemento, O, Dessen, P, Camara-Clayette, V, Cosset, F, Verhoeyen, E, Leblond, V, Ribrag, V, Cornillet-Lefebvre, P, Rameau, P, Azar, N, Charlotte, F, Morel, P, Charbonnier, J, Vyas, P, Mercher, T, Aoufouchi, S, Droin, N, Guillouf, C, Nguyen-Khac, F, Bernard, O

“…We identified a recurrent somatic mutation (Q226E) in PU.1/SPI1 in Waldenstrom macroglobulinemia, a B-cell lymphoproliferative disorder. …”

PB2087: EFFICACY OF A 3RD COVID VACCINE, INCLUDING DURING A BTKI PAUSE, IN INDIVIDUALS WITH WALDENSTRÖM MACROGLOBULINEMIA AND FOLLICULAR LYMPHOMA by K. Rankin, B. Beaton, S. Sasson, J. Raedemaecker, A. Wong, P. Hastak, C. Phetsouphanh, A. Warden, M. Patel, V. Klemm, C. M. L. Munier, A. Carey Hoppe, F. Tea, A. Pillay, A. Ospina, A. Aggarwal, O. Lavee, I. D. Caterson, S. Turville, A. D. Kelleher, F. Brilot, J. Trotman

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Case report: A rare case of coexisting Waldenstrom Macroglobulinemia and B-cell acute lymphoblastic leukemia with KMT2D and MECOM mutations by Lingling Wang, Jiao Tang, Jun Feng, Yongfen Huang, Yuexin Cheng, Hao Xu, Yuqing Miao

Subjects: “…Waldenstrom Macroglobulinemia…”
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Nephrotic Syndrome and Waldenstrom’s Macroglobulinemia: A Case Report by Ana Isabel Oliveira, Ana Azevedo, Teresa Stock da Cunha, Mário Góis, Ana Pidal

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Diagnosing, imaging, and successfully treating a debilitating case of Bing–Neel syndrome: A multidisciplinary feat by Robert N. Kerley, Niamh O'Donnell, Fiona Lynott, Riona Mulcahy, Brian Hennessy

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Diagnostic Criteria for Macular Edema Associated with Venous Occlusions by A. G. Shchuko, V. V. Bukina, A. V. Borisova, T. N. Iureva

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