P1130: ACALABRUTINIB IN TREATMENT-NAIVE OR RELAPSED/REFRACTORY WALDENSTRÖM MACROGLOBULINEMIA: 5-YEAR FOLLOW-UP OF A PHASE 2, SINGLE-ARM STUDY by R. Owen, H. McCarthy, S. Rule, S. D’Sa, S. Thomas, O. Tournilhac, F. Forconi, M. José Kersten, P. Luigi Zinzani, S. Iyengar, J. Kothari, M. Minnema, E. Kastritis, B. Cheson, H. Walter, D. Greewald, R. Calvo, C.-C. Wun, R. Furman

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P1097: CD20 CAR-T THERAPY WITH MB-106 FOR BTK INHIBITOR-REFRACTORY WALDENSTRÖM MACROGLOBULINEMIA (WM)/ LYMPHOPLASMACYTIC LYMPHOMA (LPL) – SINGLE INSTITUTION STUDY by Mazyar Shadman, Cecilia Yeung, Mary W Redman, Sang Yun Lee, Dong Hoon Lee, Susan Ra, David H Qian, Bruce Dezube, Aude Chapuis, Damian Green, Andrew Cowan, Ryan Cassaday, Hans-Peter Kiem, Houston E Warren, Filippo Milano, Jordan Gauthier, Alexandre Hirayama, Mary Kwok, Chaitra Ujjani, David Maloney, Ajay Gopal, Brian Till

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P1111: WALDENSTRÖM MACROGLOBULINEMIA IN THE VERY ELDERLY (≥75-YEAR-OLD): DESCRIPTION OF CLINICAL FEATURES AND SURVIVAL OUTCOMES IN A CASE SERIES FROM AN ITALIAN ACADEMIC CENTER by Nicolò Danesin, Mariella Lo Schirico, Greta Scapinello, Marco Carraro, Laura Bonaldi, Roberta Bertorelle, Andrea Visentin, Tamara Berno, Antonio Branca, Marcello Riva, Renato Zambello, Fabrizio Vianello, Carmela Gurrieri, Livio Trentin, Francesco Piazza

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Waldenström macroglobulinemia with secondary pure red cell aplasia in a patient with metastatic castrate resistant prostate cancer receiving an immune checkpoint inhibitor: a case report by Vaibhav Kumar, Nathan D. Montgomery, Hendrik W. van Deventer, Young E. Whang

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IgM-Associated Cryoglobulinaemia by Jahanzaib Khwaja, Simon J. Salter, Shirley D’Sa

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Defining an Ultra-Low Risk Group in Asymptomatic IgM Monoclonal Gammopathy by David F. Moreno, Arturo Pereira, Natalia Tovar, María Teresa Cibeira, Laura Magnano, María Rozman, Mónica López-Guerra, Dolors Colomer, Beatriz Martín-Antonio, Raquel Jiménez-Segura, Ignacio Isola, Luis Gerardo Rodríguez-Lobato, Aina Oliver-Caldés, Mari Pau Mena, Laura Rosiñol, Joan Bladé, Carlos Fernández de Larrea

Subjects: “…smoldering Waldenström macroglobulinemia…”
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Waldenström makroglobulinemili bir hastada mandibuler inatçı enfeksiyon olgusu by Şakir Katı, Cahit Üçok, Muhit Özcan, Selami Toprak

Subjects: “…waldenström macroglobulinemia…”
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Waldenstrom's macroglobulinemia-like B cell lymphoma with MYD88 L265P mutation and t(14;18)(q32;q21) involving IGH-MALT1 by Rie Furuta, Hiro Tatetsu, Jun-ichirou Yasunaga, Mitsunori Ueno, Kento Oshiro, Satoshi Kumanomido, Yawara Kawano, Yusuke Higuchi, Yumi Honda, Yoshiki Mikami, Kisato Nosaka, Masao Matsuoka

“…Although the MYD88 L265P mutation was identified in bone marrow mononuclear cells, which suggested the diagnosis of Waldenstrom's macroglobulinemia (WM), a fusion signal of IgH-MALT1, which is commonly observed in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) lymphoma, was also identified. …”
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Bing-Neel Syndrome with Detectable MYD88 L265P Gene Mutation as a Late Relapse Following Autologous Hematopoietic Stem Cell Transplantation for Waldenström's Macroglobulinemia by Anna J. Kopinska, Grzegorz Helbig, Anna Koclega, Slawomira Kyrcz Krzemien

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Bing–Neel Syndrome and Coexisting Pituitary Macroadenoma in a Patient with Waldenström Macroglobulinemia Revealed by ¹⁸F-FDG and ⁶⁸Ga-Pentixafor PET/CT by Qingqing Pan, Yaping Luo, Xinxin Cao, Jian Li, Jun Feng

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P1108: EFFICACY OF PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON-COVALENT (REVERSIBLE) BTK INHIBITOR IN RELAPSED/REFRACTORY WALDENSTRÖM MACROGLOBULINEMIA: RESULTS FROM THE PHASE 1/2 BRUIN STUDY by Lydia Scarfò, Manish R. Patel, Toby A. Eyre, Wojciech Jurczak, David Lewis, Thomas Gastinne, Shuo MA, Jonathon B. Cohen, Krish Patel, Jennifer R. Brown, Talha Munir, Ewa Lech-Maranda, Marc S. Hoffmann, Chaitra S. Ujjani, Bita Fakhri, Michael Wang, Koji Izutsu, Hirokazu Nagai, Constantine S. Tam, John F. Seymour, Joanna Rhodes, Julie Vose, Matthew Mckinney, James N. Gerson, Minal A. Barve, Bryone Kuss, Youngil Koh, Wei Gao, Amy S. Ruppert, Richard A. Walgren, Donald E. Tsai, Binoj Nair, Katherine Bao, Anthony R. Mato, Chan Y. Cheah, M Lia Palomba

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P1161: ASPEN: LONG-TERM FOLLOW-UP RESULTS OF A PHASE 3 RANDOMIZED TRIAL OF ZANUBRUTINIB (ZANU) VS IBRUTINIB (IBR) IN PATIENTS (PTS) WITH WALDENSTRÖM MACROGLOBULINEMIA (WM) by M. Dimopoulos, S. Opat, S. D’Sa, W. Jurczak, H.-P. Lee, G. Cull, R. G. Owen, P. Marlton, B. E. Wahlin, R. Garcia-Sanz, H. McCarthy, S. Mulligan, A. Tedeschi, J. J. Castillo, J. Czyz, C. Fernandez De Larrea Rodriguez, D. Belada, E. Libby, J. Matous, M. Motta, T. Siddiqi, M. Tani, M. Trneny, M. Minnema, C. Buske, V. Leblond, S. P. Treon, J. Trotman, W. Y. Chan, J. Schneider, H. Allewelt, A. Cohen, J. Huang, C. S. Tam

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<i>MYD88</i> Wild Type in IgM Monoclonal Gammopathies: From Molecular Mechanisms to Clinical Challenges by Tina Bagratuni, Alexandra Papadimou, Kostantina Taouxi, Meletios A. Dimopoulos, Efstathios Kastritis

Subjects: “…Waldenström macroglobulinemia…”
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Lymphoplasmacytic lymphoma and marginal zone lymphoma involving bone marrow: A diagnostic dilemma. Useful clinicopathological features to accurate the diagnosis by Patricia García‐Abellás, Ana Ferrer Gómez, Diego Bueno Sacristán, Miguel Piris Villaespesa, María Talavera Yagüe, María Eugenia Reguero Callejas, Mónica García‐Cosío

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Identification of a Candidate Gene Set Signature for the Risk of Progression in IgM MGUS to Smoldering/Symptomatic Waldenström Macroglobulinemia (WM) by a Comparative Transcriptome Analysis of B Cells and Plasma Cells by Alessandra Trojani, Barbara Di Camillo, Luca Emanuele Bossi, Livia Leuzzi, Antonino Greco, Alessandra Tedeschi, Anna Maria Frustaci, Marina Deodato, Giulia Zamprogna, Alessandro Beghini, Roberto Cairoli

Subjects: “…Waldenström Macroglobulinemia…”
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Primary central nervous system diffuse large B‐cell lymphoma masqueraded as Bing‐Neel syndrome: Steps in management and review of future directions by Lukas Delasos, Deep Phachu, Nishka Shetty, Melissa Sepulveda‐Ramos, James Vredenburgh

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Relapsed Waldenstrom’s Macroglobulinemia and Therapy-Related Myelodysplastic Syndrome with Complex Cytogenetics: A Treatment Dilemma by Shreyas Kalantri, Inderpreet Singh, Long Yang, Khadega A. Abuelgasim

Subjects: “…waldenstrom macroglobulinemia…”
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P1679: HEALTH-RELATED QUALITY OF LIFE IN PATIENTS (PTS) WITH WALDENSTRÖM MACROGLOBULINEMIA (WM) TREATED WITH ZANUBRUTINIB (ZANU) VS IBRUTINIB (IBR): RESULTS FROM THE PHASE 3 ASPEN TRIAL LONG-TERM FOLLOW-UP by Alessandra Tedeschi, Constantine Tam, Roger Owen, Christian Buske, Véronique Leblond, Meletios A. Dimopoulos, Ramón García-Sanz, Jorge Castillo, Judith Trotman, Steven Treon, Keri Yang, Boxiong Tang, Heather Allewelt, Sheel Patel, Wai Chan, Aileen Cohen, Jingjing Yan Schneider, Gisoo Barnes

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IgM-Related Immunoglobulin Light Chain (AL) Amyloidosis by Shayna Sarosiek, Andrew R. Branagan, Steven P. Treon, Jorge J. Castillo

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Diffuse large B-cell lymphoma with continuously elevated immunoglobulin M following treatment: a case report with pathologic, immunophenotypic, and molecular analyses by Fei Xiao, Yong-Mei Cai, Jian-Chen Fang, Yan-Ying Shen, Bao-Hua Yu, Yi-Wei Zhang, Di Zhu, Zi-Hua Li, Guo-Qing Li, Jian Hou, Min-Yue Zhang, Hong-Hui Huang

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