NO SAFETY CONCERNS OBSERVED WHEN THE ADJUVANTED RECOMBINANT ZOSTER VACCINE (RZV) AND THE COVID-19 MRNA-1273 BOOSTER WERE CO-ADMINISTERED IN ≥50-YEAR-OLDS by A. Naficy, P. Pirrotta, A. Kuxhausen, J. Miller, B. Leav, A. Mwakingwe-Omari

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Identification of subclinical tuberculosis in household contacts using exposure scores and contact investigations by Gry Klouman Bekken, Christian Ritz, Sumithra Selvam, Nelson Jesuraj, Anneke C. Hesseling, T. Mark Doherty, Harleen M. S. Grewal, Mario Vaz, Synne Jenum

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Combined Blockade of GARP:TGF-β1 and PD-1 Increases Infiltration of T Cells and Density of Pericyte-Covered GARP+ Blood Vessels in Mouse MC38 Tumors by Charlotte Bertrand, Pierre Van Meerbeeck, Grégoire de Streel, Noora Vaherto-Bleeckx, Fatima Benhaddi, Loïc Rouaud, Agnès Noël, Pierre G. Coulie, Nicolas van Baren, Sophie Lucas, Sophie Lucas

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Continuing to Confront COPD International Physician Survey: physician knowledge and application of COPD management guidelines in 12 countries by Davis KJ, Landis SH, Oh YM, Mannino DM, Han MK, van der Molen T, Aisanov Z, Menezes AM, Ichinose M, Muellerova H

“…Kourtney J Davis,1 Sarah H Landis,2 Yeon-Mok Oh,3 David M Mannino,4 MeiLan K Han,5 Thys van der Molen,6 Zaurbek Aisanov,7 Ana M Menezes,8 Masakazu Ichinose,9 Hana Muellerova11Worldwide Epidemiology, GlaxoSmithKline, Wavre, Belgium; 2Worldwide Epidemiology, GlaxoSmithKline, Uxbridge, UK; 3University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea; 4University of Kentucky College of Public Health, Lexington, KY, USA; 5Division of Pulmonary and Critical Care, University of Michigan, Ann Arbor, MI, USA; 6University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; 7Pulmonology Research Institute, Moscow, Russia; 8Federal University of Pelotas, Pelotas, Brazil; 9Tohoku University Graduate School of Medicine, Sendai, JapanAim: Utilizing data from the Continuing to Confront COPD (chronic obstructive pulmonary disease) International Physician Survey, this study aimed to describe physicians’ knowledge and application of the GOLD (Global initiative for chronic Obstructive Lung Disease) Global Strategy for the Diagnosis, Management and Prevention of COPD diagnosis and treatment recommendations and compare performance between primary care physicians (PCPs) and respiratory specialists.Materials and methods: Physicians from 12 countries were sampled from in-country professional databases; 1,307 physicians (PCP to respiratory specialist ratio three to one) who regularly consult with COPD, emphysema, or chronic bronchitis patients were interviewed online, by telephone or face to face. …”
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HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes by Valerie Vandenbempt, Sema Elif Eski, Manoja K. Brahma, Ao Li, Javier Negueruela, Ylke Bruggeman, Stéphane Demine, Peng Xiao, Alessandra K. Cardozo, Nicolas Baeyens, Luciano G. Martelotto, Sumeet Pal Singh, Eliana Mariño, Conny Gysemans, Esteban N. Gurzov

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Impact of a Powdered Meal Replacement on Metabolism and Gut Microbiota (PREMIUM) in individuals with excessive body weight: a study protocol for a randomised controlled trial by Patrice D Cani, Sunita Ghosh, Arya M Sharma, Caroline Richard, Jens Walter, Carla M Prado, Julia Montenegro, Camila L P Oliveira, Anissa M Armet, Aloys Berg, Laurie Mereu, Cristiane Cominetti, Nguyen Khoi Nguyen

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Knowledge, attitude, and practice toward herpes zoster (HZ) and HZ vaccination: Concept elicitation findings from a multi-country study in the Asia Pacific by Jing Chen, Sumitra Shantakumar, Jennifer Si, Regina Gowindah, Raunak Parikh, Felix Chan, Macy Chan, Won Suk Choi, Erick Huang, Kuo-Chin Huang, Li-Min Huang, Hyungwoo Kim, Choon Kit Leong, Hoe-Nam Leong, Yubin Seo, Charles Williams, Andrew TY Wong

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Continuing to Confront COPD International Patient Survey: methods, COPD prevalence, and disease burden in 2012–2013 by Landis SH, Muellerova H, Mannino DM, Menezes AM, Han MK, van der Molen T, Ichinose M, Aisanov Z, Oh YM, Davis KJ

“…Sarah H Landis,1 Hana Muellerova,1 David M Mannino,2 Ana M Menezes,3 MeiLan K Han,4 Thys van der Molen,5 Masakazu Ichinose,6 Zaurbek Aisanov,7 Yeon-Mok Oh,8 Kourtney J Davis,9 1Worldwide Epidemiology, GlaxoSmithKline, Uxbridge, UK; 2University of Kentucky College of Public Health, Lexington, KY, USA; 3Federal University of Pelotas, Pelotas, Brazil; 4Division of Pulmonary and Critical Care, University of Michigan, Ann Arbor, MI, USA; 5University Medical Center Groningen, Groningen, Netherlands; 6Tohoku University Graduate School of Medicine, Sendai, Japan; 7Pulmonology Research Institute, Moscow, Russia; 8University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea; 9Worldwide Epidemiology, GlaxoSmithKline, Wavre, Belgium Purpose: The Continuing to Confront COPD International Patient Survey aimed to estimate the prevalence and burden of COPD globally and to update findings from the Confronting COPD International Survey conducted in 1999–2000. …”
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Improving Assignments for Therapeutic and Prophylactic Treatment Within TB Households. A Potential for Immuno-Diagnosis? by Dhanasekaran Sivakumaran, Dhanasekaran Sivakumaran, Synne Jenum, Christian Ritz, Christian Ritz, Mario Vaz, Mario Vaz, Timothy Mark Doherty, Harleen M. S. Grewal, Harleen M. S. Grewal

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Single and combined impacts of irradiation and surgery on lymphatic vasculature and fibrosis associated to secondary lymphedema by F. Buntinx, A. Lebeau, L. Gillot, L. Baudin, R. Ndong Penda, F. Morfoisse, F. Lallemand, F. Lallemand, G. Vottero, C. Nizet, J. L. Nizet, S. Blacher, A. Noel, A. Noel

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Country score tool to assess readiness and guide evidence generation of immunization programs in aging adults in Europe by Thi Hao Pham, Thi Hao Pham, Ekkehard Beck, Maarten J. Postma, Maarten J. Postma, Maarten J. Postma, Bertalan Németh, Tamás Ágh, Chiara de Waure, David M. Salisbury, Nynke Nutma, Jurjen van der Schans, Jurjen van der Schans

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Improving Patient Involvement in the Lifecycle of Medicines: Insights From the EUPATI BE Survey by Lynda Grine, Lynda Grine, Rosanne Janssens, Rosanne Janssens, Eline van Overbeeke, Eline van Overbeeke, Danielle Derijcke, Danielle Derijcke, Mitchell Silva, Belinda Delys, Belinda Delys, Isabelle Dusart, Isabelle Dusart, Veerle Aertsen, Veerle Aertsen, Magali Mertens de Wilmars, Magali Mertens de Wilmars, Joanna Robaczewska, Hilde Stevens, Hilde Stevens

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HELIOS-expressing human CD8 T cells exhibit limited effector functions by Damien Neyens, Thibault Hirsch, Achraqat Abdel Aziz Issa Abdel Hadi, Nicolas Dauguet, Christophe Vanhaver, Alexandre Bayard, Claude Wildmann, Mathieu Luyckx, Mathieu Luyckx, Jean-Luc Squifflet, Jean-Luc Squifflet, Quentin D’Hondt, Céline Duhamel, Antoine Huaux, Virginie Montiel, Mélanie Dechamps, Pierre van der Bruggen, Pierre van der Bruggen

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Assay Harmonization and Use of Biological Standards To Improve the Reproducibility of the Hemagglutination Inhibition Assay: a FLUCOP Collaborative Study by Joanna Waldock, Lingyi Zheng, Edmond J. Remarque, Alexandre Civet, Branda Hu, Sarah Lartey Jalloh, Rebecca Jane Cox, Sammy Ho, Katja Hoschler, Thierry Ollinger, Claudia Maria Trombetta, Othmar G. Engelhardt, Catherine Caillet

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A Multicenter Study To Evaluate the Performance of High-Throughput Sequencing for Virus Detection by Arifa S. Khan, Siemon H. S. Ng, Olivier Vandeputte, Aisha Aljanahi, Avisek Deyati, Jean-Pol Cassart, Robert L. Charlebois, Lanyn P. Taliaferro

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Host blood-based biosignatures for subclinical TB and incipient TB: A prospective study of adult TB household contacts in Southern India by Dhanasekaran Sivakumaran, Dhanasekaran Sivakumaran, Synne Jenum, Aashish Srivastava, Vidar M. Steen, Mario Vaz, Timothy Mark Doherty, Christian Ritz, Christian Ritz, Harleen M. S. Grewal, Harleen M. S. Grewal

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Gastroenteritis attributable to rotavirus in hospitalized Saudi Arabian children in the period 2007–2008 by Khalil M, Azhar E, Kao M, Al-Kaiedi N, Alhani H, Al Olayan I, Pawinski R, Gopala K, Kandeil W, Anis S, Van Doorn LJ, DeAntonio R

“…Mohamed Khalil,1 Esam Azhar,2,3 Moujahed Kao,3 Noura Al-Kaiedi,3 Hatim Alhani,4 Ibrahim Al Olayan,5 Robert Pawinski,6,7 Kusuma Gopala,8 Walid Kandeil,7 Sameh Anis,7,9 Leen Jan Van Doorn,10 Rodrigo DeAntonio7 1Public Health and Research Development, Ministry of Health, Riyadh, Saudi Arabia; 2Medical Laboratory Technology Department, Faculty of Applied Medical Sciences, 3Special Infectious Agents Unit, Bio-Safety Level 3, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; 4Maternity and Children’s Hospital, Dammam, Saudi Arabia; 5Maternity and Children’s Hospital, Qassim, Saudi Arabia; 6Reckitt Benckiser Pharmaceuticals, Slough, UK; 7GlaxoSmithKline Vaccines, Wavre, Belgium; 8GlaxoSmithKline Pharmaceuticals Ltd, Bangalore, Karnataka, India; 9AbbVie Biopharmaceuticals GmbH, Dubai, United Arab Emirates; 10DDL Diagnostic Laboratory, Rijswijk, the Netherlands Purpose: Rotavirus (RV) is a leading cause of severe gastroenteritis (GE) in children across the world. …”
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Drug-drug interactions with antiretroviral therapy among people living with HIV in Asia and other regions: Risk factors and impact on indicators of health-related quality of life by Sejun Park, Yu-Hsiang Hsiao, Fei Yu, Keita Kambara, Brent Allan, Garry Brough, Ta-Fen Hwang, Nathalie Dang, Benjamin Young, Rickesh Patel, Andres Maldonado, Chinyere Okoli

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Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells by Marie Le Moine, Abdulkader Azouz, Guillem Sanchez Sanchez, Solange Dejolier, Muriel Nguyen, Séverine Thomas, Valdrin Shala, Hacene Dreidi, Sébastien Denanglaire, Frédérick Libert, David Vermijlen, Fabienne Andris, Stanislas Goriely

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Transcriptional drifts associated with environmental changes in endothelial cells by Yalda Afshar, Feyiang Ma, Austin Quach, Anhyo Jeong, Hannah L Sunshine, Vanessa Freitas, Yasaman Jami-Alahmadi, Raphael Helaers, Xinmin Li, Matteo Pellegrini, James A Wohlschlegel, Casey E Romanoski, Miikka Vikkula, M Luisa Iruela-Arispe

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