Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia. by Tolmachova, T, Wavre-Shapton, S, Barnard, A, Maclaren, R, Futter, C, Seabra, M

Conditional ablation of the choroideremia gene causes age-related changes in mouse retinal pigment epithelium. by Silène T Wavre-Shapton, Tanya Tolmachova, Mafalda Lopes da Silva, Clare E Futter, Miguel C Seabra

Get full text

Respiratory infections cause the release of extracellular vesicles: implications in exacerbation of asthma/COPD by Eltom, S, Dale, N, Raemdonck, K, Stevenson, C, Snelgrove, R, Sacitharan, P, Recchi, C, Wavre-Shapton, S, McAuley, D, O'Kane, C, Belvisi, M, Birrell, M

Respiratory infections cause the release of extracellular vesicles: implications in exacerbation of asthma/COPD. by Suffwan Eltom, Nicole Dale, Kristof R G Raemdonck, Christopher S Stevenson, Robert J Snelgrove, Pradeep K Sacitharan, Chiara Recchi, Silene Wavre-Shapton, Daniel F McAuley, Cecilia O'Kane, Maria G Belvisi, Mark A Birrell

Get full text

Adjuvant-Associated Peripheral Blood mRNA Profiles and Kinetics Induced by the Adjuvanted Recombinant Protein Candidate Tuberculosis Vaccine M72/AS01 in Bacillus Calmette–Guérin-Va... by Robert A. van den Berg, Laurane De Mot, Geert Leroux-Roels, Viviane Bechtold, Frédéric Clement, Margherita Coccia, Erik Jongert, Thomas G. Evans, Paul Gillard, Robbert G. van der Most

Get full text

Investigating Reports of Complex Regional Pain Syndrome: An Analysis of HPV-16/18-Adjuvanted Vaccine Post-Licensure Data by Frank Huygen, Kristin Verschueren, Candida McCabe, Jens-Ulrich Stegmann, Julia Zima, Olivia Mahaux, Lionel Van Holle, Maria-Genalin Angelo

Get full text

Knowledge, Attitudes, and Practices of European Healthcare Professionals towards Hepatitis A and Hepatitis B Vaccination in at-Risk Adults by Dasha Shamarina, Martina Sluga-O’Callaghan, George Kassianos, Alen Marijam, Vaidehi Dave, Eric Davenport, Anar Andani, Desmond Curran, Pavitra Dewda, Robert Steffen

Get full text

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers by Jean-Philippe Defour, Emilie Leroy, Sharmila Dass, Thomas Balligand, Gabriel Levy, Ian C Brett, Nicolas Papadopoulos, Céline Mouton, Lidvine Genet, Christian Pecquet, Judith Staerk, Steven O Smith, Stefan N Constantinescu

Get full text

Cost-effectiveness of the recombinant zoster vaccine in the German population aged ≥60 years old by Desirée Van Oorschot, Anastassia Anastassopoulou, Barbara Poulsen Nautrup, Lijoy Varghese, Alfred von Krempelhuber, Mohamed Neine, Stéphane Lorenc, Desmond Curran

Get full text

A phase III randomized, open-label, non-inferiority clinical trial comparing liquid and lyophilized formulations of oral live attenuated human rotavirus vaccine (HRV) in Indian inf... by Catherine Cohet, Brigitte Cheuvart, Leentje Moerman, Dan Bi, Adrian Caplanusi, Mallesh Kariyappa, Sanjay Lalwani, Monjori Mitra, Amita Sapru, Shruti Saha, P.V. Varughese, Rajeev Zachariah Kompithra, Sanjay Gandhi

Get full text

Recombinant zoster vaccine in immunocompetent and immunocompromised adults: A review of clinical studies by Agnes Mwakingwe-Omari, Nicolas Lecrenier, Abdi Naficy, Desmond Curran, Inga Posiuniene

Get full text

Prospective, multi-center post-marketing surveillance cohort study to monitor the safety of the human papillomavirus-16/18 AS04-adjuvanted vaccine in Chinese girls and women aged 9... by Qianhui Wu, Mengcen Qian, Sarah Welby, Adrienne Guignard, Dominique Rosillon, Kusuma Gopala, Yuan Xu, Keruo Liu, Yunkun He, Ning Jiang, Qin Tan, Jiamin Xie, Taoying Zhu, Qizhang Wang, Yingzi Pan, Ruikun Zeng, Jie Yang, Xiaoqian Zhao, Man Zhou, Adoración Navarro-Torné, Hongjie Yu, Dorota Borys

Get full text

Further available immunization option to prevent pneumococcal disease [v1; ref status: indexed, http://f1000r.es/4y0] by Ivo Vojtek, Bernard Hoet

Get full text

Antibody persistence up to 5 y after vaccination with a quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine in adolescents by Beatriz P. Quiambao, Ashish Bavdekar, Anand Prakash Dubey, Hemant Jain, Devayani Kolhe, Véronique Bianco, Jacqueline M. Miller, Marie Van der Wielen

Get full text

Risk factors for cervical cancer in women in China: A meta-model by Samuel Aballéa, Ekkehard Beck, Xiao Cheng, Nadia Demarteau, Xiao Li, Fangfang Ma, Mohamed Neine, Fang-Hui Zhao

Get full text

Vaccine Adjuvants: from 1920 to 2015 and Beyond by Alberta Di Pasquale, Scott Preiss, Fernanda Tavares Da Silva, Nathalie Garçon

Get full text

Immunogenicity and safety of 10-valent pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) co-administered with routine childhood vaccines in Tai... by Tzou-Yien Lin, Chun-Yi Lu, Luan-Yin Chang, Cheng-Hsun Chiu, Yhu-Chering Huang, Hans L. Bock, Haiwen Tang, Nancy François, Marta Moreira, Lode Schuerman, Li-Min Huang

Get full text

Rule of Prevention: a potential framework to evaluate preventive interventions for rare diseases by Eddie Gibson, Daniel A. Ollendorf, Steven Simoens, David E Bloom, Federico Martinón-Torres, David Salisbury, Johan Louis Severens, Mondher Toumi, Daniel Molnar, Kinga Meszaros, Woo-Yun Sohn, Najida Begum

Get full text

The potential public health impact of the respiratory syncytial virus prefusion F protein vaccine in people aged ≥60 years in Japan: results of a Markov model analysis by Daisuke Kurai, Akiko Mizukami, Victor Preckler, Frederik Verelst, Daniel Molnar, Taizo Matsuki, Yufan Ho, Ataru Igarashi

Get full text

Burden of Pertussis in Individuals with a Diagnosis of Asthma: A Retrospective Database Study in England by Bhavsar A, Aris E, Harrington L, Simeone JC, Ramond A, Lambrelli D, Papi A, Boulet LP, Meszaros K, Jamet N, Sergerie Y, Mukherjee P

“…Amit Bhavsar,1 Emmanuel Aris,2 Lauriane Harrington,3 Jason C Simeone,4 Anna Ramond,5 Dimitra Lambrelli,5 Alberto Papi,6 Louis-Philippe Boulet,7 Kinga Meszaros,8 Nicolas Jamet,8 Yan Sergerie,3 Piyali Mukherjee3 1Europe Medical Affairs, GSK, Wavre, Belgium; 2Real-World Analytics, GSK, Wavre, Belgium; 3Global Medical Affairs, GSK, Wavre, Belgium; 4Real-World Evidence, Evidera Inc., Waltham, MA, USA; 5Real-World Evidence, Evidera Ltd, London, UK; 6Respiratory Medicine, University of Ferrara, Ferrara, Italy; 7Department of Medicine, Laval University, Quebec City, Quebec, Canada; 8Value Evidence and Outcomes, GSK, Wavre, BelgiumCorrespondence: Amit Bhavsar Tel +32 10 85 51 11Email amit.b.bhavsar@gsk.comPurpose: The impact of pertussis in individuals with asthma is not fully understood. …”
Get full text