Reply to Letter to the Editor: Total Hip Arthroplasty in the Ultrayoung by Matthew Mazur, MD, Kevin Steelman, MD, Zain Sayeed, MD, MHA, Chaoyang Chen, MD, Hussein Darwiche, MD, Bryan Little, MD

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Needs assessment in a rural haitian community: Assessing the socioeconomic and cultural determinants of health by N. Othman, E. Ulrich, S. Keene, M. Smith, C. Chuang

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Differential Functional Connectivity in Anterior and Posterior Hippocampus Supporting the Development of Memory Formation by Lingfei Tang, Lingfei Tang, Patrick J. Pruitt, Qijing Yu, Qijing Yu, Roya Homayouni, Roya Homayouni, Ana M. Daugherty, Ana M. Daugherty, Ana M. Daugherty, Jessica S. Damoiseaux, Jessica S. Damoiseaux, Noa Ofen, Noa Ofen, Noa Ofen

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Non-O1, non-O139 Vibrio cholerae bacteremia in an urban academic medical center in the United States by John Shanley, Amjad Kanj, Said El Zein, Hussam Tabaja, Brett Trzcinski, Julian Horman, Hossein Salimnia, Marilynn Fairfax, Manmeet Singh

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COVID-19 Vaccine Hesitancy among Arab Americans by Mira H. Kheil, Deepti Jain, Jamil Jomaa, Brandon Askar, Yasmeen Alcodray, Shatha Wahbi, Salar Brikho, Ali Kadouh, Deanna Harajli, Zain N. Jawad, Ziad Fehmi, Malaak Elhage, Tala Tawil, Omar Fehmi, Suma J. Alzouhayli, Deema Ujayli, Noor Suleiman, Omar Kazziha, Rawan Saleh, Evi Abada, Anita Shallal, Seongho Kim, Vijaya Arun Kumar, Marcus Zervos, Michele L. Cote, Rouba Ali-Fehmi

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Dermatomal eruption as the first clinical manifestation of recurrent metastatic pancreatic cancer by Redina Bardhi, BS, Taylor Adlam, MD, Kayla St. Claire, MD, MBA, Sarah Utz Petry, MD, Meena Moossavi, MD, MPH

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EFFECT OF LONG-TERM EXPOSURE TO LOWER LOW-DENSILIPOPROTEIN CHOLESTEROL BEGINNING EARLY IN LIFE ON THE RISK OF CORONARY HEART DISEASE. A MENDELIAN RANDOMIZATION ANALYSIS by B. A. Ference, W. Yoo, I. Alesh, N. Mahajan, K. K. Mirowska, A. Mewada, J. Kahn, L. Afonso, K. A. Williams, J. M. Flack

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The UPR Transducer IRE1 Promotes Breast Cancer Malignancy by Degrading Tumor Suppressor microRNAs by Kezhong Zhang, Hui Liu, Zhenfeng Song, Yuanyuan Jiang, Hyunbae Kim, Lobelia Samavati, Hien M. Nguyen, Zeng-Quan Yang

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Mixtures of per- and polyfluoroalkyl substances (PFAS) alter sperm methylation and long-term reprogramming of offspring liver and fat transcriptome by DruAnne L. Maxwell, Oladele A Oluwayiose, Emily Houle, Katherine Roth, Karolina Nowak, Savni Sawant, Amanda L. Paskavitz, Wanqing Liu, Katherine Gurdziel, Michael C. Petriello, J. Richard Pilsner

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Radiation-Induced Esophagitis is Mitigated by Soy Isoflavones by Matthew D Fountain, Matthew D Fountain, Lisa M Abernathy, Lisa M Abernathy, Fulvio Lonardo, Shoshana E Rothstein, Michael M Dominello, Wei Chen, Shirish M Gadgeel, Michael C Joiner, Gilda Gali Hillman

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Oxidation-Responsive, EuII/III-Based, Multimodal Contrast Agent for Magnetic Resonance and Photoacoustic Imaging by Lina A. Basal, Yan Yan, Yimin Shen, E. Mark Haacke, Mohammad Mehrmohammadi, Matthew J. Allen

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Divalent metal content in diet affects severity of manganese toxicity in Drosophila by Zahraa A. Ghosn, Kailynn M. Sparks, Jacob L. Spaulding, Sanjana Vutukuri, Mirza J. J. Ahmed, Mark F. A. VanBerkum

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Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment by Adrianne Wallace-Povirk, Lisa Rubinsak, Agnes Malysa, Sijana H. Dzinic, Manasa Ravindra, Mathew Schneider, James Glassbrook, Carrie O’Connor, Zhanjun Hou, Seongho Kim, Jessica Back, Lisa Polin, Robert T. Morris, Aleem Gangjee, Heather Gibson, Larry H. Matherly

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A Novel Role of Connective Tissue Growth Factor in the Regulation of the Epithelial Phenotype by Radhika P. Gogoi, Sandra Galoforo, Alexandra Fox, Colton Morris, Harry Ramos, Vir K. Gogoi, Hussein Chehade, Nicholas K. Adzibolosu, Chenjun Shi, Jitao Zhang, Roslyn Tedja, Robert Morris, Ayesha B. Alvero, Gil Mor

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Identification of actionable targets for breast cancer intervention using a diversity outbred mouse model by Jennifer B. Jacob, Kuang-Chung Wei, Gerold Bepler, Joyce D. Reyes, Andi Cani, Lisa Polin, Kathryn White, Seongho Kim, Nerissa Viola, Julie McGrath, Anthony Guastella, CongCong Yin, Qing-Shen Mi, Benjamin L. Kidder, Kay-Uwe Wagner, Stuart Ratner, Victoria Phillips, Joanne Xiu, Prahlad Parajuli, Wei-Zen Wei

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Atomically dispersed Pb ionic sites in PbCdSe quantum dot gels enhance room-temperature NO2 sensing by Xin Geng, Shuwei Li, Lalani Mawella-Vithanage, Tao Ma, Mohamed Kilani, Bingwen Wang, Lu Ma, Chathuranga C. Hewa-Rahinduwage, Alina Shafikova, Eranda Nikolla, Guangzhao Mao, Stephanie L. Brock, Liang Zhang, Long Luo

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Calcium Release-Activated Calcium (CRAC) Channel Inhibition Suppresses Pancreatic Ductal Adenocarcinoma Cell Proliferation and Patient-Derived Tumor Growth by Husain Yar Khan, Gabriel B. Mpilla, Rachel Sexton, Srikant Viswanadha, Kumar V. Penmetsa, Amro Aboukameel, Maria Diab, Mandana Kamgar, Mohammed Najeeb Al-Hallak, Mark Szlaczky, Anteneh Tesfaye, Steve Kim, Philip A. Philip, Ramzi M. Mohammad, Asfar S. Azmi

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Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle by Paul T. Morse, Gonzalo Pérez-Mejías, Junmei Wan, Alice A. Turner, Inmaculada Márquez, Hasini A. Kalpage, Asmita Vaishnav, Matthew P. Zurek, Philipp P. Huettemann, Katherine Kim, Tasnim Arroum, Miguel A. De la Rosa, Dipanwita Dutta Chowdhury, Icksoo Lee, Joseph S. Brunzelle, Thomas H. Sanderson, Moh H. Malek, David Meierhofer, Brian F. P. Edwards, Irene Díaz-Moreno, Maik Hüttemann

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529 Impact of histology and PD-L1 status on immune checkpoint inhibitors in the treatment of non-small cell lung cancer by Seongho Kim, Tarik Hadid, Hirva Mamdani, Khalil Choucair, Hyejong Jang, Shadia I Jalal, Dipesh Uprety

Identification of PP1c-PPP1R12A Substrates Using Kinase-Catalyzed Biotinylation to Identify Phosphatase Substrates by Pavithra M. Dedigama-Arachchige, Nuwan P.N. Acharige, Xiangmin Zhang, Hannah J. Bremer, Zhengping Yi, Mary Kay H. Pflum

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