WNT3A‐loaded exosomes enable cartilage repair by Bethan L. Thomas, Suzanne E. Eldridge, Babak Nosrati, Mario Alvarez, Anne‐Sophie Thorup, Giovanna Nalesso, Sara Caxaria, Aida Barawi, James G. Nicholson, Mauro Perretti, Carles Gaston‐Massuet, Costantino Pitzalis, Alison Maloney, Adrian Moore, Ray Jupp, Francesco Dell'Accio

Get full text

Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans by Angelica Gualtieri, Nikolina Kyprianou, Louise C. Gregory, Maria Lillina Vignola, James G. Nicholson, Rachael Tan, Shin-ichi Inoue, Valeria Scagliotti, Pedro Casado, James Blackburn, Fernando Abollo-Jimenez, Eugenia Marinelli, Rachael E. J. Besser, Wolfgang Högler, I. Karen Temple, Justin H. Davies, Andrey Gagunashvili, Iain C.A.F. Robinson, Sally A. Camper, Shannon W. Davis, Pedro R. Cutillas, Evelien F. Gevers, Yoko Aoki, Mehul T. Dattani, Carles Gaston-Massuet

Get full text

Sex-specific differences in cardiac function, inflammation and injury during early polymicrobial sepsis by Sophie L. M. Walker, Chand Muthoo, Jenifer Sanchez, Ana Gutierrez Del Arroyo, Gareth L. Ackland

Get full text

Whole exome sequencing identifies deleterious rare variants in CCDC141 in familial self-limited delayed puberty by Tansit Saengkaew, Gerard Ruiz-Babot, Alessia David, Alessandra Mancini, Katia Mariniello, Claudia P. Cabrera, Michael R. Barnes, Leo Dunkel, Leonardo Guasti, Sasha R. Howard

Get full text

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice by Yusuke Shintani, Tomoya Ito, Laura Fields, Manabu Shiraishi, Yuki Ichihara, Nobuhiko Sato, Mihai Podaru, Satoshi Kainuma, Hiroyuki Tanaka, Ken Suzuki

Get full text

Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis by Esteban A. Gomez, Romain A. Colas, Patricia R. Souza, Rebecca Hands, Myles J. Lewis, Conrad Bessant, Costantino Pitzalis, Jesmond Dalli

Get full text

Allogeneic Mesenchymal Stromal Cells Transplanted Onto the Heart Surface Achieve Therapeutic Myocardial Repair Despite Immunologic Responses in Rats by Nobuko Tano, Masahiro Kaneko, Yuki Ichihara, Chiho Ikebe, Steven R. Coppen, Manabu Shiraishi, Yasunori Shintani, Kenta Yashiro, Anthony Warrens, Ken Suzuki

Get full text

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes by Myles J. Lewis, Michael R. Barnes, Kevin Blighe, Katriona Goldmann, Sharmila Rana, Jason A. Hackney, Nandhini Ramamoorthi, Christopher R. John, David S. Watson, Sarah K. Kummerfeld, Rebecca Hands, Sudeh Riahi, Vidalba Rocher-Ros, Felice Rivellese, Frances Humby, Stephen Kelly, Michele Bombardieri, Nora Ng, Maria DiCicco, Désirée van der Heijde, Robert Landewé, Annette van der Helm-van Mil, Alberto Cauli, Iain B. McInnes, Christopher D. Buckley, Ernest Choy, Peter C. Taylor, Michael J. Townsend, Costantino Pitzalis

Get full text

Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis by Guanmei Wen, Weiwei An, Jiangyong Chen, Eithne M. Maguire, Qishan Chen, Feng Yang, Stuart W. A. Pearce, Maria Kyriakides, Li Zhang, Shu Ye, Sussan Nourshargh, Qingzhong Xiao

Get full text

Invasive rhino-orbito-cerebral mucormycosis in a diabetic patient – the need for prompt treatment by Vanessa Chow, Sheema Khan, Adeola Balogun, David Mitchell, Fritz A. Mühlschlegel

Get full text

Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis by Florence L. Johnson, Nimesh S. A. Patel, Gareth S. D. Purvis, Fausto Chiazza, Jianmin Chen, Regina Sordi, Guillaume Hache, Viktoria V. Merezhko, Massimo Collino, Muhammed M. Yaqoob, Christoph Thiemermann

Get full text

Pneumococcal pulmonary valve endocarditis by Apostolos Vrettos, Paula Mota, James Nash, Iain Thorp, Max Baghai, Adam Marzetti

Get full text

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1 by Jale Yuzugulen, Julie A. Douthwaite, Elizabeth G. Wood, Inmaculada C. Villar, Nimesh S. A. Patel, James Jegard, Hubert Gaertner, Irène Rossitto-Borlat, Keith Rose, Oliver Hartley, Pedro R. Cutillas, Amrita Ahluwalia, Roger Corder

Get full text

Reaching the End-Game for GWAS: Machine Learning Approaches for the Prioritization of Complex Disease Loci by Hannah L. Nicholls, Hannah L. Nicholls, Christopher R. John, Christopher R. John, David S. Watson, David S. Watson, Patricia B. Munroe, Patricia B. Munroe, Michael R. Barnes, Michael R. Barnes, Michael R. Barnes, Michael R. Barnes, Claudia P. Cabrera, Claudia P. Cabrera, Claudia P. Cabrera

Get full text

Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis by Mathieu Ferrari, Shimobi C. Onuoha, Liliane Fossati-Jimack, Alessandra Nerviani, Pedro L. Alves, Sara Pagani, Cecilia Deantonio, Federico Colombo, Claudio Santoro, Daniele Sblattero, Costantino Pitzalis

Get full text

Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation by Dijue Sun, Urszula Stopka-Farooqui, Sayka Barry, Ezra Aksoy, Gregory Parsonage, Anna Vossenkämper, Melania Capasso, Xinyu Wan, Sherine Norris, Jennifer L. Marshall, Andrew Clear, John Gribben, Thomas T. MacDonald, Christopher D. Buckley, Márta Korbonits, Oliver Haworth

Get full text

NCK Associated Protein 1 Modulated by miRNA‐214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia by Tayyab Adeel Afzal, Le Anh Luong, Dan Chen, Cheng Zhang, Feng Yang, Qishan Chen, Weiwei An, Edmund Wilkes, Kenta Yashiro, Pedro R. Cutillas, Li Zhang, Qingzhong Xiao

Get full text

A Subset of CCL25-Induced Gut-Homing T Cells Affects Intestinal Immunity to Infection and Cancer by Hongmei Fu, Maryam Jangani, Aleesha Parmar, Guosu Wang, David Coe, Sarah Spear, Inga Sandrock, Melania Capasso, Mark Coles, Georgina Cornish, Helena Helmby, Federica M. Marelli-Berg

Get full text

ACTH signalling and adrenal development: lessons from mouse models by Tatiana V Novoselova, Peter J King, Leonardo Guasti, Louise A Metherell, Adrian J L Clark, Li F Chan

Get full text

Impact of enriched environment on murine T cell differentiation and gene expression profile by Lorenza Rattazzi, Giuseppa Piras, Samuel Brod, Koval Smith, Masahiro Ono, Fulvio D'Acquisto

Get full text