Sirt6-Mediated Endothelial-to-Mesenchymal Transition Contributes Toward Diabetic Cardiomyopathy via the Notch1 Signaling Pathway by Zhang Y, Dong Y, Xiong Z, Zhu Z, Gao F, Wang T, Man W, Sun D, Lin J, Li T, Li C, Zhao Z, Shen M, Sun D, Fan Y

“…Yan Zhang,1,* Yuan Dong,1,* Zhenyu Xiong,1,* Zhengru Zhu,2 Fanya Gao,3 Tingting Wang,1 Wanrong Man,1 Dong Sun,1 Jie Lin,1 Tongbin Li,1 Congye Li,1 Zhijing Zhao,1 Min Shen,1 Dongdong Sun,1 Yanhong Fan1 1Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, First Hospital of Lanzhou University, Lanzhou, People’s Republic of China; 3Department of Cardiology, Shaanxi Provincial People’s Hospital, Xi’an Medical University, Xi’an, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dongdong Sun; Yanhong FanDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, 127 West Changle Road, Xi’an, Shaanxi 710032, People’s Republic of ChinaTel +86 18691569930; +86 18829395402Email wintersun3@gmail.com; 18829395402@189.cnBackground: Endothelial-to-mesenchymal transition (EndMT) is an important source of myofibroblasts that directly affects cardiac function in diabetic cardiomyopathy (DCM) via an unknown underlying mechanism. …”
Get full text