Effect of ketorolac tromethamine combined with dezocine prior administration on hemodynamics and postoperative analgesia in patients undergoing laparoscopic hernia repair by Yu Wu, MD, Zenghua Cai, MD, Yanli Li, MD, Yuling Kang, MD, Bohan Fu, MD, Jinbao Wang, MD, Halil Cetingok.

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Inflammation Profiling of Critically Ill Coronavirus Disease 2019 Patients by Douglas D. Fraser, MD, PhD, Gediminas Cepinskas, DVM, PhD, Marat Slessarev, MD, MSc, Claudio Martin, MD, MSc, Mark Daley, PhD, Michael R. Miller, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, Eric K. Patterson, PhD, Claudia C. dos Santos, MD, MSc, on behalf of the Lawson COVID-19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn

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Emergency Department During Long Public Holidays by Seda DAGAR, Sibel SAHIN, Yunus YILMAZ, Ugur DURAK

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Comparing the Clinical Frailty Scale and an International Classification of Diseases-10 Modified Frailty Index in Predicting Long-Term Survival in Critically Ill Patients by Ashwin Subramaniam, MBBS, MMed, FRACP, FCICM, Ryo Ueno, MD, Ravindranath Tiruvoipati, MBBS, MS, MCh, FRCSEd, MSc, FCICM, EDIC, PhD, Jai Darvall, FANZCA, FCICM, PhD, Velandai Srikanth, MBBS, FRACP, PhD, Michael Bailey, PhD, MSc(statistics), BSc(hons), David Pilcher, MBBS MRCP(UK) FRACP FCICM, Rinaldo Bellomo, MBBS (Hons), MD, PhD, FRACP, FCICM

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Prognostic Accuracy of Presepsis and Intrasepsis Characteristics for Prediction of Cardiovascular Events After a Sepsis Hospitalization by Allan J. Walkey, MD, MSc, Daniel B. Knox, MD, Laura C. Myers, MD, MPH, Khanh K. Thai, MS, Jason R. Jacobs, PhD, Patricia Kipnis, PhD, Manisha Desai, PhD, Alan S. Go, MD, Yun Lu, MPH, Samuel M. Brown, MD, Adriana Martinez, BA, Heather Clancy, MPH, Ycar Devis, BS, Vincent X. Liu, MD, MS

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Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model by Yanqin Du, Hu Yan, Shi Zou, Tanvi Khera, Jia Li, Meihong Han, Xiaoli Yang, Baoju Wang, Jia Liu, Shuilin Sun, Xin Zheng, Ulf Dittmer, Mengji Lu, Dongliang Yang, Heiner Wedemeyer, Jun Wu

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Expression of inflammatory cytokine and inducible nitric oxide synthase genes in the small intestine and mesenteric lymph node tissues of pauci- and multibacillary sheep naturally... by Ganesh G Sonawane, Bhupendra Nath Tripathi

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Accuracy for Mortality Prediction With Additive Biomarkers Including Interleukin-6 in Critically Ill Patients: A Multicenter Prospective Observational Study by Ryo Yamamoto, MD, Junichi Sasaki, MD, Takayuki Shibusawa, MD, Taka-aki Nakada, MD, Toshihiko Mayumi, MD, Osamu Takasu, MD, Kenichi Matsuda, MD, Takashi Shimazui, MD, Hiroki Otsubo, MD, Yuto Teshima, MD, Masakazu Nabeta, MD, Takeshi Moriguchi, MD, Shigeto Oda, MD

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Major Publications in the Critical Care Pharmacotherapy Literature: 2022 by Payal K. Gurnani, PharmD, FCCM, Brooke Barlow, PharmD, Bryan Boling, DNP, FCCM, Laurence W. Busse, MD, MBA, FCCM, Jose L. Diaz-Gomez, MD, FCCM, Jenna Ford, MD, Gabrielle A. Gibson, PharmD, Ashish K. Khanna, MD, MS, FCCM, Jennifer S. Lee, PharmD, Ryan M. Rivosecchi, PharmD, Katherine M. Spezzano, PharmD, MBA, Nathan Thornton, DNP, Saraschandra Vallabhajosyula, MD, MSc, FCCM, Corey J. Witenko, PharmD, FCCM, Patrick M. Wieruszewski, PharmD

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Is a Preservation Solution for Living Donor Liver Transplantation Needed? Adding a New Chapter in LDLT! by Abdul Wahab Dogar, MBBS, FCPS, Kaleem Ullah, MBBS, FCPS, Shams-ud-din, MBBS, FCPS, Syed Hasnain Abbas, MBBS, FCPS, Azhar Hussain, MBBS, MD, Abdul Ghaffar, MBBS, FCPS, Hafiz Bilal, MBBS, FCPS, Siraj-ud-din, MBBS, FCPS, Azam Shoaib, MBBS, FCPS, Bilal Ahmed, MBBS, FCPS, MS, Hamid Raza, MBBS, FCPS, Ameer Hamza, MBBS, FCPS, Abu Bakar Hafeez Bhatti, MBBS, FRCS, FCPS, Subash Gupta, MBBS, FRCS, Sylvester M. Black, MD, PhD, Khalid Mumtaz, MBBS, MSc

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QS4: Optimizing The Decellularization Of The Rodent Epigastric Free Flap: A Comparison Of Automated SDS-based Protocols by Benjamin K. Schilling, MS, Lei Chen, MD, Chiaki Komatsu, MD, Fuat Baris Bengur, MD, Kacey G. Marra, PhD, Lauren E. Kokai, PhD, Mario G. Solari, MD

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MicroRNA‐10a Impairs Liver Metabolism in Hepatitis C Virus‐Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Tra... by Rika Horii, Masao Honda, Takayoshi Shirasaki, Tetsuro Shimakami, Ryogo Shimizu, Souma Yamanaka, Kazuhisa Murai, Kazunori Kawaguchi, Kuniaki Arai, Tatsuya Yamashita, Yoshio Sakai, Taro Yamashita, Hikari Okada, Mikiko Nakamura, Eishiro Mizukoshi, Shuichi Kaneko

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Association Between Tracheostomy and Functional, Neuropsychological, and Healthcare Utilization Outcomes in the RECOVER Cohort by Sangeeta Mehta, MD, Anita Brondani, MD, George Tomlinson, PhD, Leslie Chu, BSc, Stacey Burns, RN, Andrea Matte, BSc, Jill I. Cameron, PhD, Jan O. Friedrich, MD, Jill Rudkowski, MD, Priscila Robles, PhD, Yoanna Skrobik, MD, Margaret Herridge, MD, Neill K. J. Adhikari, MD, for the Canadian RECOVER Program Investigators and the Canadian Critical Care Trials Group (CCCTG)

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Immune Checkpoint Axes Are Dysregulated in Patients With Alcoholic Hepatitis by Wei Li, Ying Xia, Jing Yang, Haitao Guo, Guoqing Sun, Arun J. Sanyal, Vijay H. Shah, Yongliang Lou, Xiaoqun Zheng, Naga Chalasani, Qigui Yu

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A Higher Fluid Balance in the Days After Septic Shock Reversal Is Associated With Increased Mortality: An Observational Cohort Study by Niels van Mourik, MD, Bart F. Geerts, MD, PhD, MSc, MBA, Jan M. Binnekade, PhD, Denise P. Veelo, MD, PhD, Lieuwe D. J. Bos, , MD, PhD, MSc, W. Joost Wiersinga, MD, PhD, MBA, Tom van der Poll, MD, PhD, Olaf L. Cremer, MD, PhD, Marcus J. Schultz, MD, PhD, Alexander P. J. Vlaar, MD, PhD, MBA, on behalf of the MARS consortium, Laura R. A. Schouten, Lonneke A. van Vught, Maryse A. Wiewel, David S. Y. Ong, Jos F. Frencken, Marc Bonten, Peter M. C. Klein Klouwenberg, Roosmarijn T. M. van Hooijdonk, Mischa A. Huson, Marleen Straat, Esther Witteveen, Gerie J. Glas, Luuk Wieske, Brendon P. Scicluna, Hakima Belkasim-Bohoudi, Arie J. Hoogendijk

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Acellular Perfusate is an Adequate Alternative to Packed Red Blood Cells During Normothermic Human Kidney Perfusion by Alban Longchamp, MD, PhD, Fermin M. Fontan, MD, Mohamed M. Aburawi, MD, Corey Eymard, MD, Negin Karimian, MD, PhD, Danielle Detelich, MD, Casie Pendexter, BS, Stephanie Cronin, MS, Thomas Agius, MS, Sonal Nagpal, MBA, Peony Dutta Banik, BS, Shannon N. Tessier, PhD, Sinan Ozer, MBA, Francis L. Delmonico, MD, Korkut Uygun, PhD, Heidi Yeh, MD, James F. Markmann, MD, PhD

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Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts by Ayako Sato, Sei Kakinuma, Masato Miyoshi, Akihide Kamiya, Tomoyuki Tsunoda, Shun Kaneko, Jun Tsuchiya, Taro Shimizu, Eiko Takeichi, Sayuri Nitta, Fukiko Kawai‐Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanabe

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Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP‐305, a novel farnesoid X receptor agonist by Derek J. Erstad, Christian T. Farrar, Sarani Ghoshal, Ricard Masia, Diego S. Ferreira, Yin‐Ching Iris Chen, Ji‐Kyung Choi, Lan Wei, Phillip A. Waghorn, Nicholas J. Rotile, Chuantao Tu, Katherine A. Graham‐O'Regan, Mozhdeh Sojoodi, Shen Li, Yang Li, Guogiang Wang, Kathleen E. Corey, Yat Sun Or, Lijuan Jiang, Kenneth K. Tanabe, Peter Caravan, Bryan C. Fuchs

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Revisiting Post-ICU Admission Fluid Balance Across Pediatric Sepsis Mortality Risk Strata: A Secondary Analysis of a Prospective Observational Cohort Study by Mihir R. Atreya, MD, MPH, Natalie Z. Cvijanovich, MD, Julie C. Fitzgerald, MD, PhD, Scott L. Weiss, MD, MSCE, Michael T. Bigham, MD, Parag N. Jain, MD, Kamal Abulebda, MD, Riad Lutfi, MD, Jeffrey Nowak, MD, Neal J. Thomas, MD, MSc, Torrey Baines, MD, Michael Quasney, MD, PhD, Bereketeab Haileselassie, MD, Rashmi Sahay, MS, Bin Zhang, PhD, Matthew N. Alder, MD, PhD, Natalja L. Stanski, MD, Stuart L. Goldstein, MD

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The Effects of Biological Sex on Sepsis Treatments in Animal Models: A Systematic Review and a Narrative Elaboration on Sex- and Gender-Dependent Differences in Sepsis by MengQi Zhang, BSc, Joshua Montroy, MSc, Rahul Sharma, HBSc, Dean A. Fergusson, MHA, PhD, Asher A. Mendelson, MD, PhD, FRCPC, Kimberly F. Macala, MD, FRCPC, Stephane L. Bourque, PhD, Jared M. Schlechte, BSc, Mikaela K. Eng, MSc, Braedon McDonald, MD, PhD, FRCPC, Sean E. Gill, PhD, Kirsten M. Fiest, PhD, Patricia C. Liaw, MSc, PhD, Alison Fox-Robichaud, MSc, MD, FRCPC, Manoj M. Lalu, MD, PhD, FRCPC, on behalf of the Canadian Critical Care Translational Biology Group and the Sepsis Canada National Preclinical Sepsis Platform

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