Hormone therapy after the Women's Health Initiative: a qualitative study by Holtrop Jodi S, Smith Mindy A, French Linda M, Holmes-Rovner Margaret

“…<p>Abstract</p> <p>Background</p> <p>Publication of results from the Women's Health Initiative study in July 2002 was a landmark event in biomedical science related to postmenopausal women. …”
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Body composition and physical function in the Women's Health Initiative Observational Study by Jennifer W. Bea, Scott B. Going, Betsy C. Wertheim, Tamsen L. Bassford, Andrea Z. LaCroix, Nicole C. Wright, Jennifer S. Nicholas, Steven B. Heymsfield, Zhao Chen

“…We hypothesized that higher total lean mass is associated with higher physical function, and body fat inversely associated, among postmenopausal women. Women's Health Initiative Observational Study participants at Pittsburgh, PA; Birmingham, AL; and Tucson-Phoenix, AZ (1993–1998) completed dual-energy X-ray absorptiometry scans and the Rand SF-36 questionnaire at baseline and 3 y (N = 4526). …”
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Factors Associated With New‐Onset Depression Following Ischemic Stroke: The Women's Health Initiative by Joel Salinas, Roberta M. Ray, Rami Nassir, Kamakshi Lakshminarayan, Christina Dording, Jordan Smoller, Sylvia Wassertheil‐Smoller, Jonathan Rosand, Erin C. Dunn, Jacques Rossouw, Shari Ludlam, Dale Burwen, Joan McGowan, Leslie Ford, Nancy Geller, Garnet Anderson, Ross Prentice, Andrea LaCroix, Charles Kooperberg, JoAnn E. Manson, Barbara V. Howard, Marcia L. Stefanick, Rebecca Jackson, Cynthia A. Thomson, Jean Wactawski‐Wende, Marian Limacher, Robert Wallace, Lewis Kuller, Sally Shumaker

“…Methods and ResultsUsing the Women's Health Initiative, we analyzed 1424 respondents who were stroke‐free at enrollment and had no self‐reported history of depression from enrollment to their nonfatal ischemic stroke based on initiation of treatment for depression or the Burnam screening instrument for detecting depressive disorders. …”
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Rural?Urban Residence and Stroke Risk and Severity in Postmenopausal Women: The Women's Health Initiative by Shawnita Sealy-Jefferson, Molly Roseland, Michele L. Cote, Amy Lehman, Eric A. Whitsel, Jason Booza, Michael S. Simon

“…Methods: We used data from the Women's Health Initiative (WHI) (1993?2014; n?=?155,186) to test the hypothesis that women who live in rural compared with urban areas have higher stroke risk and worse stroke outcomes than urban women. …”
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Healthy Lifestyle and Clonal Hematopoiesis of Indeterminate Potential: Results From the Women's Health Initiative by Bernhard Haring, Alexander P. Reiner, Jingmin Liu, Deirdre K. Tobias, Eric Whitsel, Jeffrey S. Berger, Pinkal Desai, Sylvia Wassertheil‐Smoller, Michael J. LaMonte, Kathleen M. Hayden, Alexander G. Bick, Pradeep Natarajan, Joshua S. Weinstock, Patricia K. Nguyen, Marcia Stefanick, Michael S. Simon, Charles B. Eaton, Charles Kooperberg, JoAnn E. Manson

“…Methods and Results This analysis included 8709 postmenopausal women (mean age, 66.5 years) enrolled in the WHI (Women's Health Initiative), free of cancer or cardiovascular disease, with deep‐coverage whole genome sequencing data available. …”
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Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women's Health Initiative by Lisette T. Jacobson, Erinn M. Hade, Tracie C. Collins, Karen L. Margolis, Molly E. Waring, Linda V. Van Horn, Brian Silver, Maryam Sattari, Chloe E. Bird, Kim Kimminau, Karen Wambach, Marcia L. Stefanick

“…Of the 80 191 parous women in the Women's Health Initiative Observational Study, 2699 (3.4%) had experienced a stroke within a follow‐up period of 12.6 years. …”
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Accuracy of self‐reported treated hypertension in the women's health initiative: Comparisons with medication inventories by Michael J. LaMonte, Grace M. Milton, Connor R. Miller, Kathleen M. Hovey, Ahmed Soliman, Amy E. Millen, Jean Wactawski‐Wende

“…Participants were postmenopausal women enrolled in the Osteoporosis and Periodontal Disease (OsteoPerio) study, an ancillary investigation of the Women's Health Initiative Observational Study (WHI‐OS) at the Buffalo, New York, clinical site. …”
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Sedentary Behavior and Physical Function Decline in Older Women: Findings from the Women's Health Initiative by Rebecca Seguin, Michael LaMonte, Lesley Tinker, Jingmin Liu, Nancy Woods, Yvonne L. Michael, Cheryl Bushnell, Andrea Z. LaCroix

“…This study evaluated the association between sedentary time and physical function among postmenopausal women in the Women's Health Initiative Observational Study. Data for this prospective cohort study were collected between 1993–1998 (enrollment) and 2009, with an average of 12.3 follow-up years. …”
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Premorbid predictors of death at initial presentation of coronary heart disease in the Women's Health Initiative study by Ming-Li Chen, Jin Li, Kruthika R. Iyer, Catherine Tcheandjieu, Shirin Jimenez, Elias Levy Itshak Salfati, Liana C. Del Gobbo, Marcia L Stefanick, Manisha Desai, Xiaonan Xue, Themistocles L Assimes

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Red Blood Cell Fatty Acids and Incident Diabetes Mellitus in the Women's Health Initiative Memory Study. by William S Harris, Juhua Luo, James V Pottala, Karen L Margolis, Mark A Espeland, Jennifer G Robinson

“…DESIGN:Prospective observational cohort study nested in the Women's Health Initiative Memory Study. SETTING:General population. …”
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Cardiovascular disease and mortality after breast cancer in postmenopausal women: Results from the Women's Health Initiative. by Na-Jin Park, Yuefang Chang, Catherine Bender, Yvette Conley, Rowan T Chlebowski, G J van Londen, Randi Foraker, Sylvia Wassertheil-Smoller, Marcia L Stefanick, Lewis H Kuller

“…We hypothesized that older postmenopausal women with breast cancer would be at a higher risk of CVD than similar aged women without breast cancer and that CVD would be a major contributor to the subsequent morbidity and mortality.In a prospective Women's Health Initiative study, incident CVD events and total and cause-specific death rates were compared between postmenopausal women with (n = 4,340) and without (n = 97,576) incident invasive breast cancer over 10 years post-diagnosis, stratified by 3 age groups (50-59, 60-69, and 70-79).Postmenopausal women, regardless of breast cancer diagnosis, had similar and high levels of CVD risk factors (e.g., smoking and hypertension) at baseline prior to breast cancer, which were strong predictors of CVD and total mortality over time. …”
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Air pollution and decreased bone mineral density among Women's Health Initiative participantsResearch in context by Diddier Prada, Carolyn J. Crandall, Allison Kupsco, Marianthi-Anna Kioumourtzoglou, James D. Stewart, Duanping Liao, Jeff D. Yanosky, Andrea Ramirez, Jean Wactawski-Wende, Yike Shen, Gary Miller, Iuliana Ionita-Laza, Eric A. Whitsel, Andrea A. Baccarelli

“…Methods: We conducted a prospective observational study using data from the ethnically diverse Women's Health Initiative Study (WHI) (enrollment, September 1994–December 1998; data analysis, January 2020 to August 2022). …”
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Pregnancy loss and risk of incident CVD within 5 years: Findings from the Women's Health Initiative by Catherine E. Wright, Daniel A. Enquobahrie, Daniel A. Enquobahrie, Sarah Prager, Ian Painter, Ian Painter, Charles Kooperberg, Charles Kooperberg, Robert A. Wild, Robert A. Wild, Ki Park, Shawnita Sealy-Jefferson, Mary A. Kernic

“…We conducted an age-stratified analysis of pregnancy loss history and incident CVD in a large cohort of postmenopausal women aged 50–79 years old.MethodsAssociations between a history of pregnancy loss and incident CVD were examined among participants in the Women's Health Initiative Observational Study. Exposures were any history of pregnancy loss (miscarriage and/or stillbirth), recurrent (2+) loss, and a history of stillbirth. …”
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Promotional tone in reviews of menopausal hormone therapy after the Women's Health Initiative: an analysis of published articles. by Adriane Fugh-Berman, Christina Pike McDonald, Alicia M Bell, Emily Catherine Bethards, Anthony R Scialli

“…<h4>Background</h4>Even after the Women's Health Initiative (WHI) found that the risks of menopausal hormone therapy (hormone therapy) outweighed benefit for asymptomatic women, about half of gynecologists in the United States continued to believe that hormones benefited women's health. …”
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Pre‐diagnosis lipid levels and mortality after obesity‐related cancer diagnosis in the Women's Health Initiative cardiovascular disease biomarker cohort by Gayane Hovsepyan, Ana Barac, Theodore M. Brasky, Aladdin H. Shadyab, Amy Lehman, Eric M. McLaughlin, Nazmus Saquib, Neil M. Iyengar, Robert A. Wild, Bette J. Caan, Pinkal Desai, Jennifer Beebe Dimmer, Cynthia A. Thomson, Michael S. Simon

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Diet Quality and Cardiovascular Disease Risk in Postmenopausal Women With Type 2 Diabetes Mellitus: The Women's Health Initiative by Kristin M. Hirahatake, Luohua Jiang, Nathan D. Wong, James M. Shikany, Charles B. Eaton, Matthew A. Allison, Lisa Martin, Lorena Garcia, Oleg Zaslavsky, Andrew O. Odegaard

“…Methods and Results We analyzed prospective data from 5809 women with prevalent type 2 diabetes mellitus at baseline from the Women's Health Initiative. Diet quality was defined using alternate Mediterranean, Dietary Approach to Stop Hypertension, Paleolithic, and American Diabetes Association dietary pattern scores calculated from a validated food frequency questionnaire. …”
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Factors associated with long-term gastrointestinal symptoms in colorectal cancer survivors in the women's health initiatives (WHI study). by Claire J Han, Kerryn W Reding, Matthew F Kalady, Rachel Yung, Heather Greenlee, Electra D Paskett

“…<h4>Methods</h4>A cross-sectional study utilized data from the Women's Health Initiative (WHI) Life and Longevity After Cancer (LILAC) study that recruited postmenopausal women. …”
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Menopausal hormone therapy and the incidence of carpal tunnel syndrome in postmenopausal women: Findings from the Women's Health Initiative. by Tala Al-Rousan, Jeffrey A Sparks, Mary Pettinger, Rowan Chlebowski, JoAnn E Manson, Andrew M Kauntiz, Robert Wallace

“…<h4>Design</h4>We conducted a secondary analysis of the Women's Health Initiative's (WHI) HT trials linked to Medicare claims data. …”
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Admixture mapping of pelvic organ prolapse in African Americans from the Women's Health Initiative Hormone Therapy trial. by Ayush Giri, Katherine E Hartmann, Melinda C Aldrich, Renee M Ward, Jennifer M Wu, Amy J Park, Mariaelisa Graff, Lihong Qi, Rami Nassir, Robert B Wallace, Mary J O'Sullivan, Kari E North, Digna R Velez Edwards, Todd L Edwards

“…Here we evaluate the association between genetic ancestry and POP in AA women from the Women's Health Initiative Hormone Therapy trial. Women with grade 1 or higher classification, and grade 2 or higher classification for uterine prolapse, cystocele or rectocele at baseline or during follow-up were considered to have any POP (N = 805) and moderate/severe POP (N = 156), respectively. …”
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Factors Predicting Rubella Vaccination and Antibody in Pregnant Women in Japan: A Report from Pregnant Women Health Initiative by Akiko Iwata, Kentaro Kurasawa, Kazumi Kubota, Mizuha Odagami, Shigeru Aoki, Mika Okuda, Etsuko Miyagi

“…We used the results of the nationwide questionnaire survey conducted at obstetric facilities in the Pregnant Women Health Initiative Project (PWHI), with 23 participating hospitals recruiting pregnant women from June 2018–November 2019. …”
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