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4721
Personalised depression forecasting using mobile sensor data and ecological momentary assessment
Published 2022-11-01“…In current forecasting approaches, models are often trained on an entire population, resulting in a general model that works overall, but does not translate well to each individual in clinically heterogeneous, real-world populations. Model fairness across patient subgroups is also frequently overlooked. …”
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4722
FAKTOR-FAKTOR YANG MEMPENGARUHI DERAJAT MIOPIA PADA REMAJA (STUDI DI SMA NEGERI 2 TEMANGGUNG KABUPATEN TEMANGGUNG)
Published 2016-04-01“…Myopia as refractive error will be the most common cause of visual impairment over the world until half of the world's populations are suffer from myopia in 2020. All of age groups can get it, especially in adolescents. …”
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4723
Assessment of Groundwater Crisis in Arid and Semiarid Areas (Case Study: Jaghin and Tokahor Plain)
Published 2019-09-01“…The index of the water crisis in Iran, considering its presence in a dry and semi-arid region, is more unfavorable than the average level in the world, in other words, up to one percent of world populations live in Iran while its portion from sweet water resources is just 0.36 %. …”
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4724
The arrhythmogenic cardiotoxicity of the quinoline and structurally related antimalarial drugs: a systematic review
Published 2018-11-01“…While these findings provide further evidence of the rarity of serious cardiovascular events after treatment with these drugs, they also underscore the need for continued strengthening of pharmacovigilance systems for robust detection of rare drug adverse events in real-world populations. A standardised approach to measurement and reporting of ECG data in malaria trials is also needed. …”
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4725
Effectiveness and Safety of Dabigatran Reversal with Idarucizumab in the Taiwanese Population: A Comparison Based on Eligibility for Inclusion in Clinical Trials
Published 2023-05-01“…As the prescription of dabigatran has become increasingly popular, the generalizability of the results to real-world populations has come into question due to the broad variability of real-world patients receiving dabigatran. …”
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4726
Understanding the genetic history of the Malay and Orang Asli populations in Peninsular Malaysia by killer cell immunolobulin-like receptors (KIR)
Published 2018“…Comprehensive datasets generated from this research demonstrate the value of KIR genes content and allelic polymorphisms in elucidating genetic relationships between the Malays and OA with other world populations.…”
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4727
Genetic Diversity and Low Stratification of the Population of the United Arab Emirates
Published 2020-06-01“…Furthermore, from the 2.3 million allele frequencies obtained from genotype arrays, we identified 46,481 loci with allele frequencies that were significantly different with respect to other world populations. This comparison of allele frequencies facilitates variant prioritization in common diseases. …”
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4728
Real-World Treatment Patterns and Effectiveness of Targeted and Immune Checkpoint Inhibitor-Based Systemic Therapy in BRAF Mutation-Positive NSCLC
Published 2023-03-01“…Both dual-targeted BRAF/MEK inhibition and ICI-based regimens have evidence of benefit in this population revealing that real-world populations can experience similar clinical response and outcome to clinical trial cohorts on these treatment regimens. …”
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4729
Disease progression strikingly differs in research and real-world Parkinson’s populations
Published 2024-03-01“…. >10, p < 0.001; mini-mental state exam median decline 0.28 vs. 0.11, p < 0.001; and clinically recognized cognitive decline, p = 0.001). In real-world populations, patients are diagnosed more than eleven years later (RWD mean of 72.2 vs. research mean of 60.4, p < 0.001). …”
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4730
Paired associated SARS-CoV-2 spike variable positions: a network analysis approach to emerging variants
Published 2023-08-01“…Cliques of different sizes represented theoretical combinations of changing residues in sequence space, allowing the identification of significant aminoacidic combinations in single sequences of real-world populations. Our analytic approach that links network structural aspects to mutational aminoacidic combinations in the spike sequence population offers a novel way to understand virus epidemiology and evolution.…”
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4731
Climate change favours connectivity between virus-bearing pest and rice cultivations in sub-Saharan Africa, depressing local economies
Published 2021-11-01“…Aims Rice is a staple food for many countries, being fundamental for a large part of the worlds’ population. In sub-Saharan Africa, its importance is currently high and is likely to become even more relevant, considering that the number of people and the per-capita consumption are both predicted to increase. …”
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4732
Novel genetic association of the Furin gene polymorphism rs1981458 with COVID-19 severity among Indian populations
Published 2024-04-01“…Additionally, we examined the Furin gene using next-generation sequencing (NGS) data from 393 diverse global samples, with a particular emphasis on South Asia, to investigate its Phylogeographic structure among diverse world populations. We found a significant positive association for the SNP rs1981458 with COVID-19 CFR (p < 0.05) among diverse Indian populations at different timelines of the first and second waves. …”
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4733
Swiss experience of atezolizumab for platinum-pretreated urinary tract carcinoma: the SAUL study in real-world practice
Published 2020-05-01“…The global SAUL study evaluated atezolizumab in a broader patient population more representative of real-world populations. Among approximately 1000 patients treated in SAUL, 25 were treated in Swiss oncology centres. …”
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4734
Parametric study of portable solar-powered heat exchanger using computational fluid dynamics
Published 2016“…Its importance is highlighted by the United Nation as decade for clean water in the world populations suffer lack of portable water in stressed area such as Africa and South East Asia. …”
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4735
Ancestry informative markers single nucleotide polymorphisms panel for ancestry estimation in the Malay population
Published 2021“…The genetic structure of the Malay population can be differentiated from the other world populations used in this study using the 1250 and 2240 AIM-SNP panels selected by ipPCA-FST and 2000 AIM-SNP panels selected by In and PCAIM.…”
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4736
A quantitative systems pharmacology model for certolizumab pegol treatment in moderate-to-severe psoriasis
Published 2023-09-01“…We applied different modelling approaches: (i) an algorithm to generate vPop according to reference population values and comorbidity frequencies in real-world populations; (ii) physiologically based pharmacokinetic (PBPK) models of CZP dosing schemes in each virtual patient; and (iii) systems biology-based models of the mechanism of action (MoA) of the drug.ResultsThe combination of our different modelling approaches yielded a vPop distribution and a PBPK model that aligned with existing literature. …”
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4737
The association between ivabradine and adverse cardiovascular events in acute decompensated HFrEF patients
Published 2021-10-01“…Conclusions The current study findings suggest that ivabradine treatment is associated with reduced risks of cardiovascular mortality, all‐cause mortality, and HF rehospitalization within 1 year among patients with acute decompensated HFrEF in real‐world populations.…”
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4738
Silicate weathering and CO<sub>2</sub> consumption within agricultural landscapes, the Ohio-Tennessee River Basin, USA
Published 2012-03-01“…Natural landscapes have been reshaped into agricultural ones to meet food needs for growing world populations. These processes modify soil properties, alter hydrology, affect erosion, and consequently impact water-soil-rock interactions such as chemical weathering. …”
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4739
First report of Burkholderia gladioli causing bacterial panicle blight of rice in Malaysia
Published 2022“…Rice (Oryza sativa) is a staple food for most of the world's populations, particularly in Asia (Gumma et al. 2011). …”
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4740
Seroprevalence and risk factors for hepatitis B virus infection among general population in Northern India Soroprevalência e fatores de risco para infecção pelo vírus da hepatite B...
Published 2008-06-01“…Epidemiological data reveals that there are 360 million carriers of hepatitis-B virus throughout the globe and 78% of the world populations’ hail from Asia. Though several studies from Indian sub-continent have provided an estimate of the prevalence of this viral infection, there exist only few studies, which reflect the status in the general population. …”
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