Immune Evasion Strategies of Ranaviruses and Innate Immune Responses to These Emerging Pathogens by Leon Grayfer, Francisco De Jesús Andino, Guangchun Chen, Gregory V. Chinchar, Jacques Robert

“…Concurrently, by using animal infection models with extensively characterized immune systems, such as the African clawed frog, <em>Xenopus laevis</em>, it is becoming evident that components of innate immunity are at the forefront of virus-host interactions. …”
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Identifying the evolutionary building blocks of the cardiac conduction system. by Bjarke Jensen, Bastiaan J D Boukens, Alex V Postma, Quinn D Gunst, Maurice J B van den Hoff, Antoon F M Moorman, Tobias Wang, Vincent M Christoffels

“…Using conserved genetic markers, we found that the conduction system design of lizard (Anolis carolinensis and A. sagrei), frog (Xenopus laevis) and zebrafish (Danio rerio) adults is strikingly similar to that of embryos of mammals (mouse Mus musculus, and man) and chicken (Gallus gallus). …”
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A circadian-dependent preference for light displayed by Xenopus tadpoles is modulated by serotonin by John R. Bruno, Uwemedimo G. Udoh, Jason G. Landen, Paige O. Osborn, Carson J. Asher, Jasper E. Hunt, Kara G. Pratt

“…Here, we investigate the modulation of the innate preference for light displayed by the Xenopus laevis tadpole, an exceptionally invasive and well-studied organism that is known to display several different innate visually guided behaviors. …”
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Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel. by Konstas, A, Koch, J, Tucker, S, Korbmacher, C

“…We hypothesized that CFTR may provide a regulatory link between ENaC and Kir1.1. In Xenopus laevis oocytes co-expressing both ENaC and CFTR, the CFTR currents were 3-fold larger than those in oocytes expressing CFTR alone due to an increased expression of CFTR in the plasma membrane. …”

Effects of S-adenosylmethionine decarboxylase, polyamines, amino acids, and weak bases (amines and ammonia) on development and ribosomal RNA synthesis in Xenopus embryos. by Shiokawa, K, Aso, M, Kondo, T, Takai, J, Yoshida, J, Mishina, T, Fuchimukai, K, Ogasawara, T, Kariya, T, Tashiro, K, Igarashi, K

“…We have been studying control mechanisms of gene expression in early embryogenesis in a South African clawed toad Xenopus laevis, especially during the period of midblastula transition (MBT), or the transition from the phase of active cell division (cleavage stage) to the phase of extensive morphogenesis (post-blastular stages). …”

Regulation of neuronal high-voltage activated CaV2 Ca2+ channels by the small GTPase RhoA by Rousset, M, Cens, T, Menard, C, Bowerman, M, Bellis, M, Brusés, J, Raoul, C, Scamps, F, Charnet, P

“…Using heterologous expression in Xenopus laevis oocytes, we show that RhoA activity reduces Ba(2+) currents through CaV2.1, CaV2.2 and CaV2.3 Ca(2+) channels independently of CaVβ subunit. …”

DNA replication licensing in somatic and germ cells. by Eward, K, Obermann, E, Shreeram, S, Loddo, M, Fanshawe, T, Williams, C, Jung, H, Prevost, A, Blow, J, Stoeber, K, Williams, G

“…Studies in yeast, Drosophila melanogaster and Xenopus laevis have characterised the molecular machinery that constitutes the licensing system, but it remains to be determined how this important evolutionary conserved pathway is regulated in Homo sapiens. …”

DNA replication licensing in somatic and germ cells by Eward, K, Obermann, E, Shreeram, S, Loddo, M, Fanshawe, T, Williams, C, Jung, H, Prevost, A, Blow, J, Stoeber, K, Williams, G

“…Studies in yeast, Drosophila melanogaster and Xenopus laevis have characterised the molecular machinery that constitutes the licensing system, but it remains to be determined how this important evolutionary conserved pathway is regulated in Homo sapiens. …”

Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics. by Adèle Salin-Cantegrel, Masoud Shekarabi, Sarah Rasheed, François M Charron, Janet Laganière, Rebecca Gaudet, Patrick A Dion, Jean-Yves Lapointe, Guy A Rouleau

“…We identified a highly conserved proline-rich sequence within the C-terminus of the cotransporter which when mutated leads to loss of the KCC3-dependent regulatory volume decrease (RVD) response in Xenopus Laevis oocytes. Using SH3 domain arrays, we found that this poly-proline motif is a binding site for SH3-domain containing proteins in vitro. …”
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Mammalian odorant receptor tuning breadth persists across distinct odorant panels. by Devin Kepchia, Benjamin Sherman, Rafi Haddad, Charles W Luetje

“…ORs were expressed in Xenopus laevis oocytes and assayed by two-electrode voltage clamp electrophysiology. …”
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Engineering of <i>Saccharomyces cerevisiae</i> for 24-Methylene-Cholesterol Production by Jiao Yang, Changfu Li, Yansheng Zhang

“…Three versions of DHCR7 originating from different organisms—including the DHCR7 from <i>Physalis angulata</i> (PhDHCR7) newly discovered in this study, as well as the previously reported OsDHCR7 from <i>Oryza sativa</i> and XlDHCR7 from <i>Xenopus laevis</i>—were assessed for their ability to produce 24-methylene-cholesterol. …”
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Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome. by Tobias D Schneider, Jose M Arteaga-Salas, Edith Mentele, Robert David, Dario Nicetto, Axel Imhof, Ralph A W Rupp

“…To investigate this issue we analysed histones isolated from four different developmental stages of Xenopus laevis by mass spectrometry. In toto, we quantified 59 modification states on core histones H3 and H4 from blastula to tadpole stages. …”
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Spadin Selectively Antagonizes Arachidonic Acid Activation of TREK-1 Channels by Ruolin Ma, Anthony Lewis

“…Heterologous expression in Xenopus laevis oocytes and electrophysiological analysis using two-electrode voltage clamp in standard bath solutions was used to characterize the pharmacological profile of wild-type and mutant murine TREK-1 and TREK-2 channels using previously established human K2P activators; arachidonic acid (AA), cis-4,7,10,13,16,19-docosahexaenoic acid (DHA), BL-1249, and cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) and inhibitors; spadin and barium (Ba2+). …”
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Differential expression of anterior gradient gene AGR2 in prostate cancer by Knutzen Laura A, Bagryanova Lora, Liebeskind Emily S, Horvath Steve, Alavi Mohammad, Mah Vei, Maresh Erin L, Zhou Yong, Chia David, Liu Alvin Y, Goodglick Lee

“…<p>Abstract</p> <p>Background</p> <p>The protein AGR2 is a putative member of the protein disulfide isomerase family and was first identified as a homolog of the <it>Xenopus laevis </it>gene XAG-2. AGR2 has been implicated in a number of human cancers. …”
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SINE RNA induces severe developmental defects in Arabidopsis thaliana and interacts with HYL1 (DRB1), a key member of the DCL1 complex. by Marie-Noëlle Pouch-Pélissier, Thierry Pélissier, Taline Elmayan, Hervé Vaucheret, Drasko Boko, Michael F Jantsch, Jean-Marc Deragon

“…We also show that HYL1, upon binding to RNA substrates, induces conformational changes that force single-stranded RNA regions to adopt a structured helix-like conformation. Xenopus laevis ADAR1, but not Arabidopsis DRB4, binds SB1 RNA in the same region as HYL1, suggesting that SINE RNAs bind only a subset of dsRBPs. …”
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An update on MyoD evolution in teleosts and a proposed consensus nomenclature to accommodate the tetraploidization of different vertebrate genomes. by Daniel J Macqueen, Ian A Johnston

“…Additionally, two MyoD paralogues have been characterised in the allotetraploid frog, Xenopus laevis. This has lead to a confusing nomenclature since MyoD paralogues have been named outside of an appropriate phylogenetic framework. …”
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An archetype and scaling of developmental tissue dynamics across species by Yoshihiro Morishita, Sang-Woo Lee, Takayuki Suzuki, Hitoshi Yokoyama, Yasuhiro Kamei, Koji Tamura, Aiko Kawasumi-Kita

“…Here, we address this issue by focusing on limb morphogenesis in Gallus gallus domesticus (chicken) and Xenopus laevis (African clawed frog). To compare the deformation dynamics between tissues with different sizes/shapes as well as their developmental rates, we introduce a species-specific rescaled spatial coordinate and a common clock necessary for cross-species synchronization of developmental times. …”
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Vestibular Influence on Vertebrate Skeletal Symmetry and Body Shape by Clayton Gordy, Clayton Gordy, Hans Straka

“…This role has been validated by removal of otolith signals on one side during a specific developmental period in Xenopus laevis tadpoles. This intervention causes severe scoliotic deformations that remain permanent and extend into adulthood. …”
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Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function by Charlotte Heymans, Ophélie Delcorte, Catherine Spourquet, Mylah Villacorte-Tabelin, Sébastien Dupasquier, Younes Achouri, Siam Mahibullah, Pascale Lemoine, Maria S. Balda, Karl Matter, Christophe E. Pierreux

“…MarvelD3 is a tight junction protein expressed in adult epithelial and endothelial cells. In Xenopus laevis, MarvelD3 morphants present differentiation defects of several ectodermal derivatives. …”
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Simplified Method for Rapid Purification of Soluble Histones by Nives Ivić, Bernhard Groschup, Silvija Bilokapić, Mario Halić

“…In the present study, we show that co-expression of <i>Xenopus laevis</i> histone pairs leads to production of soluble H2AH2B heterodimer and (H3H4)2 heterotetramer. …”
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