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21
Analysis of behaviour of rhabdomyosarcoma cells under electrical stimulation
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Thesis -
22
Genetic relatedness of Candida strains isolated from women with vaginal candidiasis in Malaysia
Published 2003“…Six yeast species were detected: Candida albicans, Candida glabrata, Candida lusitaniae, Candida famata, Candida krusei and Candida parapsilosis. …”
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23
Exploring microbial diversity in green honey from Pulau Banggi Sabah: a preliminary study
Published 2024“…Molds were only detected in raw green honey, while osmophilic yeast counts were higher in raw green honey (16000 ± 0.03 cfu/g) compared to processed green honey (120 ± 0.02 cfu/g). …”
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Article -
24
Roles of the actin cytoskeleton in structuring the cortical endoplasmic reticulum.
Published 2011“…This rearrangement is thought to be dependent on actin cytoskeleton in yeast. The actin cytoskeleton consists of three structures: actin cables, actin patches and actomyosin rings. …”
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Thesis -
25
Development and evaluation of a loop-mediated isothermal amplification (LAMP) method for Candida glabrata detection
Published 2024“…The “gold standard” culture method for yeast detection, has low sensitivity with severe consequences, increasing morbidity and mortality rates. …”
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26
Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity
Published 2020“…In addition, studies in yeast found HMGA2 to prevent the formation of a potentially topologically driven, pathological fork structure, thereby preventing fork collapse and hinting at a possible mechanism of fork protection. …”
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Thesis-Doctor of Philosophy -
27
Use of co-cultivation method to stimulate the production of antimicrobial natural products from mangrove microorganisms
Published 2015“…Cryptic gene clusters from actinomycetes are suspected to harbor potential in producing bioactive products, and in this study, co-cultivation is utilized to stimulate these cryptic gene clusters in novel antibiotics production. 10 actinomycete strains isolated from Sungei Buloh Wetland Reserve were co-cultured with Mycobacterium Abscessus and Asperigillus Westerdijikiae in two liquid mediums, Glucose-Yeast extract-Malt extract (GYM) and Minimum Media (MM). …”
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Final Year Project (FYP) -
28
Structural basis of RNA binding by leucine zipper GCN4
Published 2013“…To support further mechanistic studies, herein, we elucidated RNA binding interface of the GCN4 leucine zipper motif from yeast. Solution NMR experiments showed that the LZ-RNA interaction interface is located in the first two heptads of LZ moiety, and that only the dimeric (coiled coil) LZ conformation is capable of binding RNA. …”
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Journal Article -
29
A regulatory role for repeated decoy transcription factor binding sites in target gene expression
Published 2024“…Using a synthetic system in budding yeast, we demonstrate that repeated decoy sites inhibit gene expression by sequestering a transcriptional activator and converting the graded dose–response of target promoters to a sharper, sigmoidal‐like response. …”
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Article -
30
Discovery of stabilized functional mutants of human aquaporin 1
Published 2016“…A cell-based freeze-thaw functionality assay that was developed by the lab was conducted on yeast Saccharomyces cerevisiae cells transformed with the plasmids to identify the functional mutants, i.e., mutants that express the mutated AQP1 protein that would allow them to exhibit a protective effect in response to rapid freezing. ~ 5% of mutants from a total of 2816 screened from thirty-three 96-well plates were identified after a series of initial and verification screens. …”
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Final Year Project (FYP) -
31
Optimization of carbon and nitrogen sources for phytase production by Mitsuokella jalaludinii, a new rumen bacterial species
Published 2002“…Methods and Results: Replacement of glucose, cellobiose and starch in MF1 medium by RB or palm kernel cake and replacement of trypticase peptone and yeast extract in the medium by SM or enzymatic digested soybean milk significantly increased the phytase production by M. jalaludinii. …”
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Article -
32
Phase separation of a microtubule plus-end tracking protein into a fluid fractal network
Published 2025“…Here, we have study the phase separation of Bik1, a CLIP-170 family member and key +TIP involved in budding yeast cell division. Bik1 is a dimer with a rod-shaped conformation primarily defined by its central coiled-coil domain. …”
Journal article -
33
Modelling pH dynamics, SCOBY biomass formation, and acetic acid production of Kombucha fermentation using black, green, and Oolong Teas
Published 2024“…Kombucha is a traditional, fermented beverage made with an essential biomaterial known as SCOBY (symbiotic culture of bacteria and yeast). Three different tea types, namely black, green, and oolong, were compared in kombucha fermentation in terms of pH dynamics, the formation of SCOBY biomass, and the production of acetic acid. …”
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Article -
34
Application of scoby bacterial cellulose as hydrocolloids on physicochemical, textural and sensory characteristics of mango jam
Published 2024“…BACKGROUND: The scoby pellicle of symbiotic culture of bacteria and yeast is a by-product from kombucha fermentation. …”
Article -
35
Development of fed-batch strategy to produce bacteria cellulose
Published 2023“…First, batch fermentation mode was carried out to determine the glucose consumption profile of Gluconacetobacter xylinus using Yeast Extract Glucose Chloramphenicol Medium (YGC). …”
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Article -
36
Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs
Published 2024“…During the COVID-19 pandemic in Qatar, many patients who were severely ill were colonized and infected by Candida auris, an invasive multidrug-resistant yeast pathogen that spreads through nosocomial transmission within healthcare facilities. …”
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Journal Article -
37
Legionella pneumophila filamentous morphological form and the generation of novel spherical form upon interaction with protozoan hosts
Published 2012“…Our investigation showed that filamentation cannot be neatly pegged to a single dominant factor but is promoted under a concerted influence of environmental conditions leaning towards (i) higher than ambient temperatures, at 37-42°C, (ii) static fluid movement, and (iii) with at least a minimal organic content of 5% buffered yeast extract, or equivalent. In the course of investigating interaction of the filamentous form with protozoan hosts, a spherical form was discovered. …”
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Thesis -
38
Characterization of the near native conformational states of the SAM domain of Ste11 protein by NMR spectroscopy
Published 2016“…SAM domain of the Ste11 protein of budding yeast plays important roles in mitogen-activated protein kinase cascades. …”
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Journal Article -
39
On the total synthesis of complex alkaloids
Published 2024“…Following a concerted investigation into C−H oxidation for the former and a transfer of chirality approach for the latter, a Baker’s yeast reduction is adopted as an efficient route towards an enantioenriched, oxidised pyrrolidine building block which is advanced to a pentacyclic intermediate.…”
Thesis -
40
The bHLH transcription factor OsPRI1 activates the Setaria viridis PEPC1 promoter in rice
Published 2024“…To engineer C<sub>4</sub> into a C<sub>3</sub> plant, it is essential to understand how C<sub>4</sub> genes, such as <i>phosphoenolpyruvate carboxylase (PEPC1)</i>, are regulated to be expressed at high levels and in a cell-specific manner.</li> <li>Yeast one-hybrid screening was used to show that OsPRI1, a rice bHLH transcription factor involved in iron homeostasis, binds to the <i>Setaria viridis PEPC1</i> promoter. …”
Journal article