Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases by Shu Shen, Yaxian Zhang, Zhiyun Yin, Qiong Zhu, Jingyuan Zhang, Tiantian Wang, Yaohui Fang, Xiaoli Wu, Yuan Bai, Shiyu Dai, Xijia Liu, Jiayin Jin, Shuang Tang, Jia Liu, Manli Wang, Yu Guo, Fei Deng

“…Moreover, anidulafungin exerts an antiviral effect in inhibiting the entry of other viruses including SARS-CoV-2, SFTSV-related Guertu virus and Heartland virus, Crimean-Congo hemorrhagic fever virus, Zika virus, and Herpes simplex virus 1. Conclusions The results demonstrated that the antifungal drug, anidulafungin, could effectively inhibit virus infection by interfering with virus entry, suggesting it may be utilized for the clinical treatment of infectious viral diseases, in addition to its FDA-approved use as an antifungal. …”
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Infectious Disease Transmission in Solid Organ Transplantation: Donor Evaluation, Recipient Risk, and Outcomes of Transmission by Sarah L. White, PhD, William Rawlinson, FRACP, FRCPA, PhD, Peter Boan, FRACP, FRCPA, Vicky Sheppeard, FAFPHM, Germaine Wong, FRACP, PhD, Karen Waller, MBBS, Helen Opdam, FRACP, FCICM, John Kaldor, PhD, Michael Fink, MD, FRACS, Deborah Verran, MD, FRACS, Angela Webster, PhD, FRCP, FRACP, Kate Wyburn, FRACP, PhD, Lindsay Grayson, MD, FRACP, FAFPHM, FRCP, FIDSA, Allan Glanville, MD, FRACP, Nick Cross, MD, PhD, Ashley Irish, FRACP, Toby Coates, FRACP, PhD, Anthony Griffin, FRACS, Greg Snell, MD, FRACP, Stephen I. Alexander, MD, FRACP, Scott Campbell, FRACP, PhD, Steven Chadban, FRACP, PhD, Peter Macdonald, MD, FRACP, PhD, Paul Manley, FRACP, Eva Mehakovic, Vidya Ramachandran, MBBS, Alicia Mitchell, PhD, Michael Ison, MD

“…The review also covers emerging risks associated with recent epidemics (eg, Zika virus) and the risk of transmission of nonendemic pathogens related to donor travel history or country of origin. …”
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Molecular basis of the chikungunya virus replication complex assembly: platform for antiviral discovery by Tan, Yaw Bia

“…CHIKV is often misdiagnosed as dengue and zika virus infections due to the same transmission vector (Aedes mosquitoes) and their similarity in clinical symptoms. …”
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Antimicrobial Activity of Cyclic-Monomeric and Dimeric Derivatives of the Snail-Derived Peptide Cm-p5 against Viral and Multidrug-Resistant Bacterial Strains by Melaine González-García, Fidel Morales-Vicente, Erbio Díaz Pico, Hilda Garay, Daniel G. Rivera, Mark Grieshober, Lia Raluca Olari, Rüdiger Groß, Carina Conzelmann, Franziska Krüger, Fabian Zech, Caterina Prelli Bozzo, Janis A. Müller, Alexander Zelikin, Heinz Raber, Dennis Kubiczek, Frank Rosenau, Jan Münch, Steffen Stenger, Barbara Spellerberg, Octavio L. Franco, Armando A. Rodriguez Alfonso, Ludger Ständker, Anselmo J. Otero-Gonzalez

“…Moreover, they inhibited Herpes Simplex Virus 2 (HSV-2) infection in a concentration-dependent manner, but had no effect on infection by the Zika Virus (ZIKV) or pseudoparticles of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2). …”
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Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells by Luiz Carlos Caires-Júnior, Ernesto Goulart, Uirá Souto Melo, Bruno Henrique Silva Araujo, Lucas Alvizi, Alessandra Soares-Schanoski, Danyllo Felipe de Oliveira, Gerson Shigeru Kobayashi, Karina Griesi-Oliveira, Camila Manso Musso, Murilo Sena Amaral, Lucas Ferreira daSilva, Renato Mancini Astray, Sandra Fernanda Suárez-Patiño, Daniella Cristina Ventini, Sérgio Gomes da Silva, Guilherme Lopes Yamamoto, Suzana Ezquina, Michel Satya Naslavsky, Kayque Alves Telles-Silva, Karina Weinmann, Vanessa van der Linden, Helio van der Linden, João Ricardo Mendes de Oliveira, Nivia Maria Rodrigues Arrais, Adriana Melo, Thalita Figueiredo, Silvana Santos, Joanna Goes Castro Meira, Saulo Duarte Passos, Roque Pacheco de Almeida, Ana Jovina Barreto Bispo, Esper Abrão Cavalheiro, Jorge Kalil, Edécio Cunha-Neto, Helder Nakaya, Robert Andreata-Santos, Luis Carlos de Souza Ferreira, Sergio Verjovski-Almeida, Paulo Lee Ho, Maria Rita Passos-Bueno, Mayana Zatz

“…Zika virus (ZIKV) infection can cause congenital Zika syndrome (CZS), but the underlying mechanisms are poorly understood. …”
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Causes of death in children with congenital Zika syndrome in Brazil, 2015 to 2018: A nationwide record linkage study by Maria da Conceição N. Costa, Luciana Lobato Cardim, Cynthia A. Moore, Eliene dos Santos de Jesus, Rita Carvalho-Sauer, Mauricio L. Barreto, Laura C. Rodrigues, Liam Smeeth, Lavínia Schuler-Faccini, Elizabeth B. Brickley, Wanderson K. Oliveira, Eduardo Hage Carmo, Julia Moreira Pescarini, Roberto F. S. Andrade, Moreno M. S. Rodrigues, Rafael V. Veiga, Larissa C. Costa, Giovanny V. A. França, Maria Gloria Teixeira, Enny S. Paixão

“…It is necessary to develop evidence-based health protocols and raising awareness of conditions associated with high mortality in children affected by congenital Zika virus infection to guide health professionals responsible for caring for these children.…”
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Does the human placenta express the canonical cell entry mediators for SARS-CoV-2? by Roger Pique-Regi, Roberto Romero, Adi L Tarca, Francesca Luca, Yi Xu, Adnan Alazizi, Yaozhu Leng, Chaur-Dong Hsu, Nardhy Gomez-Lopez

“…By contrast, receptors for Zika virus and cytomegalovirus, which cause congenital infections, are highly expressed by placental cell types. …”
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HOW CAN THE PUBLIC BE BETTER PROTECTED AGAINST COVID-19? by Connie CR Gan, Febi Dwirahmadi

“…Although a series of emerging and re-emerging infectious diseases, from Avian flu to Zika virus, may have created more public awareness, whether leaders can translate this newfound awareness into meaningful policies and action is debatable. …”
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La infección por virus Zika: una nueva emergencia de salud pública con gran impacto mediático by Joan A. Caylà, Ángela Domínguez, Elena Rodríguez Valín, Fernando de Ory, Ana Vázquez, Claudia Fortuny

“…Abstract: Infection with Zika virus (ZV) has become a new epidemic, with great impact on the media, and is having a strong effect in Latin American countries. …”
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Isogenic human trophectoderm cells demonstrate the role of NDUFA4 and associated variants in ZIKV infection by Liuliu Yang, Yuling Han, Ting Zhou, Lauretta A. Lacko, Mohsan Saeed, Christina Tan, Ron Danziger, Jiajun Zhu, Zeping Zhao, Clare Cahir, Alice Maria Giani, Yang Li, Xue Dong, Dorota Moroziewicz, Daniel Paull, Zhengming Chen, Aaron Zhong, Scott A. Noggle, Charles M. Rice, Qibin Qi, Todd Evans, Shuibing Chen

“…Recently, we reported a human induced pluripotent stem cell (hiPSC) array-based GWAS method, identifying NDUFA4 as a host factor for Zika virus (ZIKV) infection. In this study, we extended our analysis to trophectoderm cells, which constitute one of the major routes of mother-to-fetus transmission of ZIKV during pregnancy. …”
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NSUN2-mediated m5C methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections by Hongyun Wang, Jiangpeng Feng, Cong Zeng, Jiejie Liu, Zhiying Fu, Dehe Wang, Yafen Wang, Lu Zhang, Jiali Li, Ao Jiang, Miao He, Yuanyuan Cao, Kun Yan, Hao Tang, Deyin Guo, Ke Xu, Xiang Zhou, Li Zhou, Ke Lan, Yu Zhou, Yu Chen

“…Moreover, infection with Sendai virus (SeV), vesicular stomatitis virus (VSV), herpes simplex virus 1 (HSV-1), or Zika virus (ZIKV) resulted in a reduction of endogenous NSUN2 levels. …”
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A Placenta Derived C-Terminal Fragment of β-Hemoglobin With Combined Antibacterial and Antiviral Activity by Rüdiger Groß, Richard Bauer, Franziska Krüger, Elke Rücker-Braun, Lia-Raluca Olari, Ludger Ständker, Nico Preising, Armando A. Rodríguez, Armando A. Rodríguez, Carina Conzelmann, Fabian Gerbl, Daniel Sauter, Frank Kirchhoff, Benjamin Hagemann, Jasmina Gačanin, Jasmina Gačanin, Tanja Weil, Tanja Weil, Yasser B. Ruiz-Blanco, Elsa Sanchez-Garcia, Wolf-Georg Forssmann, Annette Mankertz, Sabine Santibanez, Steffen Stenger, Paul Walther, Sebastian Wiese, Barbara Spellerberg, Jan Münch, Jan Münch

“…The peptide was inactive against Human Immunodeficiency Virus Type 1, Rubella and Zika virus infection, suggesting a specific anti-HSV-2 mechanism. …”
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Factors that impact on recruitment to vaccine trials in the context of a pandemic or epidemic: a qualitative evidence synthesis by Meskell, P, Biesty, LM, Dowling, M, Roche, K, Meehan, E, Glenton, C, Devane, D, Shepperd, S, Booth, A, Cox, R, Chan, XHS, Houghton, C

“…The other studies related to Ebola virus, tuberculosis, Zika virus and COVID‐19. We developed 20 key findings, under three broad themes (with seven subthemes), that described the factors that people consider when deciding whether to take part in a vaccine trial for a pandemic or epidemic disease. …”

Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil by Bruno H. G. A. Milhim, Leonardo C. da Rocha, Ana C. B. Terzian, Carolina C. P. Mazaro, Marcos T. Augusto, Adriana Luchs, Nathalia Zini, Livia Sacchetto, Barbara F. dos Santos, Pedro H. C. Garcia, Rodrigo S. Rocha, Elisabete Liso, Vânia M. S. Brienze, Gislaine C. D. da Silva, Nikos Vasilakis, Cássia F. Estofolete, Maurício L. Nogueira

“…A total of 255 cerebrospinal fluid (CSF) samples collected from January 2016 to December 2017 were tested for dengue virus (DENV 1-4), Zika virus (ZIKV), and Chikungunya virus (CHIKV) in addition to other neurotropic arboviruses of interest, using genetic and serologic assays. …”
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Rapid viral metagenomics using SMART-9N amplification and nanopore sequencing [version 2; peer review: 2 approved] by Ingra M. Claro, Thais M. Coletti, Mariana S. Ramundo, Ian N. Valenca, Camila A. M. da Silva, Flavia C. S. Sales, Darlan S. Candido, Jaqueline G. de Jesus, Erika R. Manuli, Alvina Clara Felix, Anderson de Paula, Mariana C. Pinho, Pamela dos Santos Andrade, Mariene R. Amorim, William M. Souza, Joshua Quick, Esper G. Kallas, José Luiz Proenca-Modena, Nuno Rodrigues Faria, José Eduardo Levi, Nicholas J. Loman, Ester C. Sabino

“…The methods were developed using viral isolates, clinical samples, and compared to a gold-standard amplicon-based method. From a Zika virus isolate the SMART-9N approach recovered 10kb of the 10.8kb RNA genome in a single nanopore read. …”
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Isolation of Flaviviruses and Alphaviruses with Encephalitogenic Potential Diagnosed by Evandro Chagas Institute (Pará, Brazil) in the Period of 1954–2022: Six Decades of Discoveri... by Ana Lucia Monteiro Wanzeller, Fabio Silva da Silva, Leonardo Henrique Almeida Hernández, Landerson Junior Leopoldino Barros, Maria Nazaré Oliveira Freitas, Maissa Maia Santos, Ercília de Jesus Gonçalves, Jamilla Augusta Sousa Pantoja, Creuza de Sousa Lima, Maxwell Furtado Lima, Luiz Roberto Oliveira Costa, Liliane Leal das Chagas, Iveraldo Ferreira Silva, Tania Cristina Alves da Silveira da Cunha, Bruna Lais Sena do Nascimento, Helena Baldez Vasconcelos, Elizabeth Salbe Travassos da Rosa, Sueli Guerreiro Rodrigues, Raimunda do Socorro da Silva Azevedo, Lívia Carício Martins, Lívia Medeiros Neves Casseb, Jannifer Oliveira Chiang, Joaquim Pinto Nunes Neto, Ana Cecília Ribeiro Cruz, Valéria Lima Carvalho, Pedro Fernando da Costa Vasconcelos, Eliana Vieira Pinto da Silva

“…Viruses with encephalitogenic potential can cause neurological conditions of clinical and epidemiological importance, such as <i>Saint Louis encephalitis virus</i>, <i>Venezuelan equine encephalitis virus</i>, <i>Eastern equine encephalitis virus</i>, <i>Western equine encephalitis virus</i>, <i>Dengue virus</i>, <i>Zika virus</i>, <i>Chikungunya virus</i>, <i>Mayaro virus</i> and <i>West Nile virus</i>. …”
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Conocimiento sobre dengue en una región endémica de Perú. Estudio de base poblacional by César Gutiérrez, Juan José Montenegro-Idrogo

“…Alternative vector control methods to manage the Zika virus outbreak: more haste, less speed. Lancet Glob Health. 2016;4(6):e364.   4. …”
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The Ethics of Brazilian Abortion Law in the Age of Zika by Alix Masters

“…Web. 03 July 2017. [6] "Zika Virus." Centers for Disease Control and Prevention. …”
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Secretory pathways and multiple functions of nonstructural protein 1 in flavivirus infection by Senzhao Zhang, Senzhao Zhang, Senzhao Zhang, Yu He, Yu He, Yu He, Zhen Wu, Zhen Wu, Zhen Wu, Mingshu Wang, Mingshu Wang, Mingshu Wang, Renyong Jia, Renyong Jia, Renyong Jia, Dekang Zhu, Dekang Zhu, Dekang Zhu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Juan Huang, Juan Huang, Juan Huang, Xumin Ou, Xumin Ou, Xumin Ou, Qun Gao, Qun Gao, Qun Gao, Di Sun, Di Sun, Di Sun, Ling Zhang, Yanling Yu, Shun Chen, Shun Chen, Shun Chen, Anchun Cheng, Anchun Cheng, Anchun Cheng

“…The genus Flavivirus contains a wide variety of viruses that cause severe disease in humans, including dengue virus, yellow fever virus, Zika virus, West Nile virus, Japanese encephalitis virus and tick-borne encephalitis virus. …”
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Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes by Rajeshwer S. Sankhala, Vincent Dussupt, Gina Donofrio, Gregory D. Gromowski, Rafael A. De La Barrera, Rafael A. Larocca, Letzibeth Mendez-Rivera, Anna Lee, Misook Choe, Weam Zaky, Grace Mantus, Jaime L. Jensen, Wei-Hung Chen, Neelakshi Gohain, Hongjun Bai, Michael K. McCracken, Rosemarie D. Mason, David Leggat, Bonnie M. Slike, Ursula Tran, Ningbo Jian, Peter Abbink, Rebecca Peterson, Eric Araujo Mendes, Rafael Freitas de Oliveira Franca, Guilherme Amaral Calvet, Ana Maria Bispo de Filippis, Adrian McDermott, Mario Roederer, Mayda Hernandez, Amie Albertus, Edgar Davidson, Benjamin J. Doranz, Morgane Rolland, Merlin L. Robb, Rebecca M. Lynch, Dan H. Barouch, Richard G. Jarman, Stephen J. Thomas, Kayvon Modjarrad, Nelson L. Michael, Shelly J. Krebs, M. Gordon Joyce

“…Summary: Zika virus (ZIKV) is an emerging pathogen that causes devastating congenital defects. …”
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