Genetic Diversity among Four Populations of <i>Aedes aegypti</i> (Diptera: Culicidae) from Honduras as Revealed by Mitochondrial DNA Cytochrome Oxidase I by Denis Escobar, Bryan Ortiz, Oscar Urrutia, Gustavo Fontecha

“…<i>Ae. aegypti</i> is the main vector of several febrile diseases called arboviruses (dengue, yellow fever, chikungunya, and zika viruses), which represent an important public health problem. …”
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Transcriptional and Translational Dynamics of Zika and Dengue Virus Infection by Kamini Singh, Maria Guadalupe Martinez, Jianan Lin, James Gregory, Trang Uyen Nguyen, Rawan Abdelaal, Kristy Kang, Kristen Brennand, Arnold Grünweller, Zhengqing Ouyang, Hemali Phatnani, Margaret Kielian, Hans-Guido Wendel

“…Zika virus (ZIKV) and dengue virus (DENV) are members of the Flaviviridae family of RNA viruses and cause severe disease in humans. …”
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In Vitro and In Vivo Models to Study the Zoonotic Mosquito-Borne Usutu Virus by Emna Benzarti, Mutien Garigliany

“…Whilst USUV actually appears less threatening than some other emergent arboviruses, the lessons learned from Chikungunya, Dengue, and Zika viruses during the past few years should not be ignored. …”
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The first record of the invasive mosquito species Aedes albopictus in Chişinӑu, Republic of Moldova, 2020 by Tatiana Șuleșco, Galina Bușmachiu, Unchana Lange, Jonas Schmidt-Chanasit, Renke Lühken

“…Abstract Background In Europe, Aedes albopictus is an important vector of chikungunya virus and Dirofilaria nematodes and has been involved in local autochthonous circulation of dengue and Zika viruses. Due to the ongoing spread, targeted field surveillance at potential points of entry of invasive Aedes mosquitoes was initiated by the Republic of Moldova in 2020 as part of the transboundary “Invasive Aedes Mosquitoes COST-Action project.” …”
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Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro by Sheli R. Radoshitzky, Patrick Iversen, Xianghan Lu, Jing Zou, Suzanne J. F. Kaptein, Kelly S. Stuthman, Sean A. Van Tongeren, Jesse Steffens, Ruoyu Gong, Hoa Truong, Annapurna A. Sapre, Huiling Yang, Xiaodong Xie, Jia Jun Chia, Zhijuan J. Song, Stacey M. Leventhal, Josolyn Chan, Alex Shornikov, Xin Zhang, David Cowfer, Helen Yu, Travis Warren, Tomas Cihlar, Danielle P. Porter, Johan Neyts, Pei-Yong Shi, Jay Wells, John P. Bilello, Joy Y. Feng

“…Using cell-based assays, we show that remdesivir can inhibit infection of flaviviruses (such as dengue 1–4, West Nile, yellow fever, Zika viruses), picornaviruses (such as enterovirus and rhinovirus), and filoviruses (such as various Ebola, Marburg, and Sudan virus isolates, including novel geographic isolates), but is ineffective or is significantly less effective against orthomyxoviruses (influenza A and B viruses), or hepadnaviruses B, D, and E. …”
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Assessment of immunogenicity and efficacy of a Zika vaccine using modified vaccinia Ankara virus as carriers by López-Camacho, C, Kim, Y, Abbink, P, Larocca, R, Huiskonen, J, Barouch, D, Reyes-Sandoval, A

“…Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has spread to more than 70 countries worldwide since 2015. …”

Consensus and uncertainty in the geographic range of Aedes aegypti and Aedes albopictus in the contiguous United States: Multi-model assessment and synthesis. by Andrew J Monaghan, Rebecca J Eisen, Lars Eisen, Janet McAllister, Harry M Savage, John-Paul Mutebi, Michael A Johansson

“…(Stegomyia) albopictus (Skuse) mosquitoes can transmit dengue, chikungunya, yellow fever, and Zika viruses. Limited surveillance has led to uncertainty regarding the geographic ranges of these vectors globally, and particularly in regions at the present-day margins of habitat suitability such as the contiguous United States. …”
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A peridomestic Aedes malayensis population in Singapore can transmit yellow fever virus. by Elliott F Miot, Fabien Aubry, Stéphanie Dabo, Ian H Mendenhall, Sébastien Marcombe, Cheong H Tan, Lee C Ng, Anna-Bella Failloux, Julien Pompon, Paul T Brey, Louis Lambrechts

“…Effective control of the main domestic mosquito vector Aedes aegypti in Singapore has failed to prevent re-emergence of dengue, chikungunya and Zika viruses in the last two decades, raising suspicions that peridomestic mosquito species untargeted by domestic vector control measures may contribute to arbovirus transmission. …”
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In silico design of a multi-epitope Chimera from Aedes aegypti salivary proteins OBP 22 and OBP 10: A promising candidate vaccine by Sathish Sankar

“…Background & objectives: The emergence and re-emergence of arboviruses such as dengue, Chikungunya and Zika viruses causing morbidity and mortality around the globe are of serious concern. …”
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Immunization with different recombinant West Nile virus envelope proteins induces varying levels of serological cross-reactivity and protection from infection by Rebecca Weiß, Leila Issmail, Alexandra Rockstroh, Thomas Grunwald, Jasmin Fertey, Sebastian Ulbert

“…These antibodies can lead to enhancement of infection with heterologous flaviviruses, which is a major concern for potential vaccines in areas with co-circulation of different flaviviruses, e.g. Dengue or Zika viruses.MaterialTo reduce the potential of inducing cross-reactive antibodies, we performed an immunization study in mice using WNV E proteins with either wild type sequence or a mutated FL, and WNV E domain III which does not contain the FL at all.Results and discussionOur data show that all antigens induce high levels of WNV-binding antibodies. …”
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Ecological processes underlying the emergence of novel enzootic cycles: Arboviruses in the neotropics as a case study. by Sarah Guth, Kathryn A Hanley, Benjamin M Althouse, Mike Boots

“…We ground our discussion in the neotropics, where four arthropod-borne viruses (arboviruses) of zoonotic origin-yellow fever, dengue, chikungunya, and Zika viruses-have separately been introduced into the human population. …”
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Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti. by Lucie Danet, Guillaume Beauclair, Michèle Berthet, Gonzalo Moratorio, Ségolène Gracias, Frédéric Tangy, Valérie Choumet, Nolwenn Jouvenet

“…Yellow fever virus (YFV) belongs to the genus Flavivirus, which includes human viruses transmitted by Aedes mosquitoes, such as dengue and Zika viruses. The live-attenuated YFV-17D vaccine has been used safely and efficiently on a large scale since the end of World War II. …”
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Geographic shifts in the bioclimatic suitability for Aedes aegypti under climate change scenarios in Colombia by Cristiam Victoriano Portilla Cabrera, John Josephraj Selvaraj

“…The Dengue, Chikungunya and Zika viruses are arboviruses predominantly transmitted to humans through the bite of the female mosquito Aedes aegypti. …”
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Aedes albopictus in a recently invaded area in Spain: effects of trap type, locality, and season on mosquito captures by Mario Garrido, Jesús Veiga, Marta Garrigós, Manuel Morales-Yuste, Jesús Recuero-Gil, Josué Martínez-de la Puente

“…Recent findings incriminate Ae. albopictus in the local transmission of several pathogens causing human diseases, including dengue, chikungunya, and Zika viruses and worm parasites as Dirofilaria. In Spain, the establishment of Ae. albopictus occurred in 2004 and it rapidly expanded, currently reaching southern provinces and creating novel epidemiological scenarios in recently invaded areas. …”
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Assessing the Potential Interactions between Cellular miRNA and Arboviral Genomic RNA in the Yellow Fever Mosquito, <i>Aedes aegypti</i> by Pei-Shi Yen, Chun-Hong Chen, Vattipally Sreenu, Alain Kohl, Anna-Bella Failloux

“…Here, we carried out genomic analyses to identify <i>Aedes aegypti</i> miRNAs that potentially interact with various lineages and genotypes of chikungunya, dengue, and Zika viruses. By using prediction tools with distinct algorithms, several miRNA binding sites were commonly found within different genotypes/and or lineages of each arbovirus. …”
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Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development by Megan A. Files, Clairissa A. Hansen, Vanessa C. Herrera, Craig Schindewolf, Alan D. T. Barrett, David W. C. Beasley, Nigel Bourne, Gregg N. Milligan

“…We suggest that OROV is an undervalued pathogen much like chikungunya, Schmallenberg, and Zika viruses were before they emerged. Overall, OROV is an important emerging disease that has been under-investigated and has the potential to cause large epidemics in the future. …”
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Broad-spectrum monoclonal antibodies against chikungunya virus structural proteins: Promising candidates for antibody-based rapid diagnostic test development. by Aekkachai Tuekprakhon, Orapim Puiprom, Tadahiro Sasaki, Johan Michiels, Koen Bartholomeeusen, Emi E Nakayama, Michael K Meno, Juthamas Phadungsombat, Ralph Huits, Kevin K Ariën, Natthanej Luplertlop, Tatsuo Shioda, Pornsawan Leaungwutiwong

“…These mAbs possessed broad reactivity to all three CHIKV genotypes, while most of the mAbs lacked cross-reactivity towards Sindbis, dengue, and Zika viruses. Two of the mAbs also lacked cross-reactivity towards other alphaviruses, including O'nyong-nyong, Ross River, Mayaro, Western Equine Encephalitis, Eastern Equine Encephalitis, and Venezuelan Equine Encephalitis viruses. …”
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Larvicidal activity of Ocimum campechianum, Ocotea quixos and Piper aduncum essential oils against Aedes aegypti by Scalvenzi Laura, Radice Matteo, Toma Luciano, Severini Francesco, Boccolini Daniela, Bella Antonino, Guerrini Alessandra, Tacchini Massimo, Sacchetti Gianni, Chiurato Matteo, Romi Roberto, Di Luca Marco

“…Aedes aegypti, the main arbovirus vector of the Yellow fever, Dengue, Chikungunya and Zika viruses, is widely distributed in tropical and subtropical areas throughout the world. …”
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Design and Testing of Novel Lethal Ovitrap to Reduce Populations of Aedes Mosquitoes: Community-Based Participatory Research between Industry, Academia and Communities in Peru and... by Valerie A Paz-Soldan, Josh Yukich, Amara Soonthorndhada, Maziel Giron, Charles S Apperson, Loganathan Ponnusamy, Coby Schal, Amy C Morrison, Joseph Keating, Dawn M Wesson

“…Dengue virus (and Chikungunya and Zika viruses) is transmitted by Aedes aegypti and Aedes albopictus mosquitoes and causes considerable human morbidity and mortality. …”
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Permethrin resistance in Aedes aegypti: Genomic variants that confer knockdown resistance, recovery, and death. by Karla Saavedra-Rodriguez, Corey L Campbell, Saul Lozano, Patricia Penilla-Navarro, Alma Lopez-Solis, Francisco Solis-Santoyo, Americo D Rodriguez, Rushika Perera, William C Black Iv

“…Pyrethroids are one of the few classes of insecticides available to control Aedes aegypti, the major vector of dengue, chikungunya, and Zika viruses. Unfortunately, evolving mechanisms of pyrethroid resistance in mosquito populations threaten our ability to control disease outbreaks. …”
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