Real Time, in vivo Observation of Oxidative Carbohydrate Metabolism Reveals the Key Regulatory Role of Acetyl-Carnitine as a Substrate Buffer in the Heart by Schroeder, M, Atherton, H, Dodd, M, Clarke, K, Radda, G, Tyler, D

Early increase in marker of neuronal integrity with antidepressant treatment of major depression: 1H-magnetic resonance spectroscopy of N-acetyl-aspartate. by Taylor, M, Godlewska, B, Norbury, R, Selvaraj, S, Near, J, Cowen, P

“…This study used magnetic resonance spectroscopy to assess effects of short-term treatment with escitalopram on N-acetyl-aspartate (NAA), a marker of neuronal integrity. …”

1-[5-Acetyl-4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridin-3-yl]eth anone monohydrate by Reddy, P.B., Vijayakumar, V., Sarveswari, S., Narasimhamurthy, T., Tiekink, E.R.T.

1-(2-Hydr­oxy-5-methyl­phen­yl)ethanone [(1H-indol-3-­yl)acet­yl]hydrazone by Ali, Hapipah Mohd, Kadir, Zuraini, Basirun, Wan Jefrey, Rizal, Mohd Razali, Ng, Seik Weng

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Evaluation of entamoeba histolytica acetyl co-a synthetase recombinant protein (rehacs) for diagnosis of acute amoebic liver abscess in moribund hamsters by Ching, Guee Cher

“…This study aimed to evaluate the diagnostic potential of a well-defined recombinant protein of E. histolytica acetyl-Co-A synthetase (rEhACS) using serum samples from hamsters with acute fatal ALA. …”
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Negative-Stain Electron Microscopy Reveals Dramatic Structural Rearrangements in Ni-Fe-S-Dependent Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase by Cohen, Steven E, Brignole, Edward J, Wittenborn, Elizabeth C, Can, Mehmet, Thompson, Samuel, Ragsdale, Stephen W, Drennan, Catherine L

“…© 2020 Elsevier Ltd Cohen et al. demonstrate that carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) undergoes wider conformational changes than previously reported. …”
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Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine) and its C(2)-epimer by Abraham, E, Candela-Lena, J, Davies, S, Georgiou, M, Nicholson, R, Roberts, P, Russell, A, Sanchez-Fernandez, E, Smith, A, Thomson, J

“…The highly diastereoselective conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide to a γ-silyloxy-α,β-unsaturated ester and in situ enolate oxidation with (+)-(camphorsulfonyl)oxaziridine has been used as the key step in the asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine) and its C(2)-epimer. © 2007 Elsevier Ltd. …”

5-Acetyl-3-hydroxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one by Rida, M., Alsubari, A., Essassi, E.M., Zouihri, H., Ng, S.W.

“…The amino group of the ring system is a hydrogen-bond donor to the oxo O atom of an inversion-related molecule, and the hydroxy group is a hydrogen-bond donor to the acetyl O atom of another inversion-related molecule. …”

2-[4-Acetyl-5-(biphenyl-4-yl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]phenyl acetate by Yehye, W.A., Ariffin, A., Rahman, N.A., Ng, S.W.

2- 4-Acetyl-5-(biphenyl-4-yl)-4,5-dihydro-1,3,4-oxadiazol-2-yl phenyl acetate by Ariffin, Azhar, Ng, S.W., Yehye, W.A., Rahman, N.A.

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Dynamic simulation on the recovery of 2-acetyl pyrroline (2-ap) in a packed bed column using rice husk char as solid adsorbent by Carla Goncalves De Olievera Sarmento, Mohd Hardyianto Vai Bahrun, Jidon Janaun, Awang Bono, Duduku Krishnaiah

“…Fragrant rice is known to contain the aromatic compound of 2-Acetyl Pyrroline (2-AP). This compound has been known as a major compound that gives fragrant characteristics in rice. …”
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Evaluation of Entamoeba histolytica Acetyl Co-A Synthetase Recombinant Protein (rEhACS) for Serodiagnosis of Acute Amoebic Liver Abscess in Humans by Sith, Nur Shafiqa Md

“…This study was done to evaluate the diagnostic potential of a well-defined recombinant protein of E. histolytica acetyl-Co-A synthetase (rEhACS) using serum samples from patients warded in HUSM who were diagnosed with ALA based on clinical symptoms, ultrasound imaging, and positive serology with commercial indirect haemagglutination kit, IHA (Cellognost® Amebiasis Kit, Dade Behring Marburg GmbH, Germany). …”
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Ionic strength and PH effects in the kinetically controlled synthesis of benzylpenicillin by nucleophilic deacylation of free and immobilized phenyl-acetyl-penicillin amidase with 6-aminopenicillanic acid/ by 416857 Kasche, Volker, Galunsky, B.

CONTRASTING LIGAND PHOTOLABILISATIONS IN THE ACETYL COMPLEXES [(ETA(5)-C(5)R(5))FE(CO)(PPH(3))COME] (R=H, ME) by Davies, S, Watkins, W

Synthesis, Characterization, X-ray crystallography, acetyl cholinesterase inhibition and antioxidant activities of some novel ketone derivatives of gallic hydrazide-derived schiff bases by Gwaram, N.S., Abdelwahab, S.I., Khaledi, H., Hassandarvish, P., Hadi, A.H.A., Yehye, W.A., Alhadi, A.A., Othman, R., Chung, L.Y., Sukumaran, S.D., Buckle, M.J.C., Abdulla, M.A., Ali, Hapipah Mohd

“…N-(1-(5-bromo-2-hydroxyphenyl)-ethylidene)-3,4,5-trihydroxybenzohydrazide (2) was the most potent inhibitor of human acetyl cholinesterase, giving an inhibition rate of 77% at 100 mu M. …”
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Effect of low temperature blanching, cysteine-HCI, N-acetyl-L-cysteine, Na metabisulphite and drying temperatures on the firmness and nutrient content of dried carrots by Mohamed, Suhaila, Hussein, Rosli

“…LTLT blanching allows pectin methyl esterase to deesterify pectin which can then react with calcium to form salt bridges. 0.3% L-cysteine-HCl was found to be most effective in preventing ascorbic acid loss and obtaining a product with the highest rehydration ability, compared to pretreatments with 0.3% N-acetyl-L-cysteine and 0.1% sodium metabisulphite. …”

Diastereoselective conjugate reduction with samarium diiodide: asymmetric synthesis of methyl (2S,3R)-N-acetyl-2-amino-2,3-dideuterio-3-phenylpropionate. by Davies, S, Rodríguez-Solla, H, Tamayo, J, Garner, A, Smith, A

“…A highly diastereoselective conjugate reduction using SmI2 and D2O has been demonstrated on a homochiral benzylidene diketopiperazine template, giving methyl (2S,3R)-N-acetyl-2-amino-2,3-dideuterio-3-phenylpropionate in 93% de and 90% ee after deprotection, hydrolysis and N-acetylation.…”

1-(2,4-dihydroxyphenyl)ethanone (1H-indol-3-yl)acetyl hydrazone-2-(1H-indol-3-yl)aceto-hydrazide(1/1) by Ali, Hapipah Mohd, Ng, S.W., Jefrey, B.W., Zuraini, K.

A master protocol to investigate a novel therapy acetyl-L-leucine for three ultra-rare neurodegenerative diseases: Niemann-Pick type C, the GM2 gangliosidoses, and ataxia telangiectasia by Fields, T, Patterson, M, Bremova-Ertl, T, Belcher, G, Billington, I, Churchill, GC, Davis, W, Evans, W, Flint, S, Galione, A, Granzer, U, Greenfield, J, Karl, R, Kay, R, Lewi, D, Mathieson, T, Meyer, T, Pangonis, D, Platt, FM, Tsang, L, Verburg, C, Factor, M, Strupp, M

“…To investigate both the symptomatic and disease-modifying effects of treatment, N-acetyl-L-leucine is assessed during two treatment sequences: a 6-week parent study and 1-year extension phase. …”

Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition. by Abraham, E, Brock, E, Candela-Lena, J, Davies, S, Georgiou, M, Nicholson, R, Perkins, J, Roberts, P, Russell, A, Sánchez-Fernández, E, Scott, P, Smith, A, Thomson, J

“…The highly diastereoselective anti-aminohydroxylation of (E)-gamma-tri-iso-propylsilyloxy-alpha,beta-unsaturated esters, via conjugate addition of lithium (S)-N-benzyl-N-(alpha-methylbenzyl)amide and subsequent in situ enolate oxidation with (+)-(camphorsulfonyl)oxaziridine, has been used as the key step in the asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine (20% yield over 7 steps), the anhydrophytosphingosine jaspine B (10% yield over 9 steps), 2-epi-jaspine B (14% yield over 9 steps), and the Prosopis alkaloid deoxoprosophylline (26% yield over 7 steps).…”