Hepcidin is regulated by promoter-associated histone acetylation and HDAC3 by Pasricha, S, Lim, P, Duarte, T, Casu, C, Oosterhuis, D, Mleczko-Sanecka, K, Suciu, M, Rita da Silva, A, Al-Hourani, K, Arezes, J, McHugh, K, Gooding, S, Frost, J, Wray, K, Santos, A, Porto, G, Repapi, E, Gray, N, Draper, S, Ashley, N, Soilleux, E, Olinga, P, Muckenthaler, M, Hughes, J, Rivella, S, Milne, T, Armitage, A, Drakesmith, A

The therapeutic potential of acetyl-lysine and methyl-lysine effector domains by Brennan, P, Filippakopoulos, P, Knapp, S

Small molecules as tools to study the chemical epigenetics of lysine acetylation by Schiedel, M, Conway, S

“…Lysine acetylation has emerged as a key post-translational modification found at many sites throughout the cell. …”

Acetyl-Leucine slows disease progression in lysosomal storage disorders by Kaya, E, Smith, DA, Smith, C, Morris, L, Fineran, P, Morten, KJ, Poulton, J, Frances Platt

“…Acetyl-DL-leucine is a derivative of the branched chain amino acid leucine. …”

Acetyl-Leucine slows disease progression in lysosomal storage disorders by Kaya, E, Smith, DE, Smith, C, Morris, L, Bremova-Ertl, T, Cortina-Borja, M, Fineran, P, Morten, KJ, Poulton, J, Spencer, J, Strupp, ML, Platt, F

The therapeutic potential of acetyl-lysine and methyl-lysine effector domains by Brennan, P, Filippakopoulos, P, Knapp, S

“…This review focusses on reader domains that recognize acetylated and methylated lysine and arginine residues. …”

Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis by Finkemeier, I, Laxa, M, Miguet, L, Howden, A, Sweetlove, L

“…Furthermore, our study suggests that Lys acetylation may be an important posttransitional modification in the chloroplast, since four Calvin cycle enzymes were acetylated. …”

Bromodomains control amyloid-like aggregation of aberrantly acetylated proteins by Olzscha, H, Fedorov, O, Kessler, B, Knapp, S, La Thangue, N

Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis. by Finkemeier, I, Laxa, M, Miguet, L, Howden, A, Sweetlove, L

“…Furthermore, our study suggests that Lys acetylation may be an important posttranslational modification in the chloroplast, since four Calvin cycle enzymes were acetylated. …”

Pathway engineering and metabolic flux analysis of acetyl-coA biosynthesis. by Hee, Kai Sheng.

“…Acetyl-CoA is a highly energetic molecule which serves as a precursor for both catabolic and anabolic process in a cell. …”
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Absence of relationship between isoniazid-induced hepatic disturbances and acetylator phenotype by Perpustakaan UGM, i-lib

“…Key Words: isoniazid, hepatic disturbance, acetylator phenotype…”

Tuning transcription factor availability through acetylation-mediated genomic redistribution by Louphrasitthiphol, P, Siddaway, R, Loffreda, A, Pogenberg, V, Friedrichsen, H, Schepsky, A, Faria-Shayler, P, Zeng, Z, Lu, M, Strub, T, Freter, R, Lisle, R, Suer, E, Thomas, B, Schuster-Boeckler, P, Filippakopoulos, P, Middleton, M, Lu, X, Patton, EE, Davidson, I, Lambert, J-P, Wilmanns, M, Steingrímsson, E, Mazza, D, Goding, C

“…The results reveal a paradoxical acetylation-mediated molecular clutch that tunes transcription factor availability via genome-wide redistribution and couples BRAF to tumorigenesis. …”

Druggability analysis and structural classification of bromodomain acetyl-lysine binding sites. by Vidler, L, Brown, N, Knapp, S, Hoelder, S

“…Bromodomains are readers of the epigenetic code that specifically bind acetyl-lysine containing recognition sites on proteins. …”

CONFORMATIONAL-ANALYSES FOR ACETYL AND FORMYL LIGANDS BOUND TO TRANSITION-METAL AUXILIARIES by Davies, S, Smallridge, A

“…Conformational analyses for acetyl and formyl ligands bound to transition metal auxiliaries reveal that, after considering primary stereoelectronic effects where appropriate, the conformations adopted by acetyl ligands are determined primarily by steric interactions while the corresponding formyl conformations are determined primarily by dipolar and electrostatic forces. …”

An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion. by Beckouët, F, Hu, B, Roig, M, Sutani, T, Komata, M, Uluocak, P, Katis, V, Shirahige, K, Nasmyth, K

“…Establishment of cohesion during S phase depends on acetylation of Smc3's nucleotide-binding domain (NBD) by the Eco1 acetyl transferase. …”

Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases. by Chen, D, Vollmar, M, Rossi, M, Phillips, C, Kraehenbuehl, R, Slade, D, Mehrotra, P, von Delft, F, Crosthwaite, S, Gileadi, O, Denu, J, Ahel, I

“…Sirtuins utilize NAD(+) to deacetylate proteins, yielding O-acetyl-ADP-ribose (OAADPr) as a reaction product. …”

Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases. by Chen, D, Vollmar, M, Rossi, M, Phillips, C, Kraehenbuehl, R, Slade, D, Mehrotra, P, von Delft, F, Crosthwaite, S, Gileadi, O, Denu, J, Ahel, I

“…Sirtuins utilize NAD+ to deacetylate proteins, yieldingO-acetyl-ADP-ribose (OAADPr) as a reaction product. …”

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands by Hewings, D, Wang, M, Philpott, M, Fedorov, O, Uttarkar, S, Filippakopoulos, P, Picaud, S, Vuppusetty, C, Marsden, B, Knapp, S, Conway, S, Heightman, T, American Chemical Society

“…Bromodomains bind acetylated lysines, acting as readers of the histone-acetylation code. …”

Acetylation of 5-aminosalicylic acid by isolated human colonic epithelial cells. by Ireland, A, Priddle, J, Jewell, D

“…This study investigates the acetylation of 5-aminosalicylic acid by isolated human colonic epithelial cells. 2. …”

Cracking the histone code: Developing inhibitors of bromodomain-acetyl-lysine interactions by Conway, S