N-acetyl transferase 2 polymorphism and advanced stages of endometriosis in South Indian women. by Babu, K, Rao, K, Reddy, N, Kanakavalli, M, Zondervan, K, Deenadayal, M, Singh, A, Shivaji, S, Kennedy, S

“…Aylamine-N-acetyl transferase is a phase II detoxification enzyme encoded by the gene NAT2. …”

Association between endometriosis and N-acetyl transferase 2 polymorphisms in a UK population. by Nakago, S, Hadfield, R, Zondervan, K, Mardon, H, Manek, S, Weeks, D, Barlow, D, Kennedy, S

“…Homozygotes for the NAT 2 *4 wild type allele are fast NAT acetylators, while heterozygotes with one wild-type allele and a variant NAT 2 *5, *6 or *7 allele have reduced enzyme activity, and individuals with two variant alleles are slow acetylators. …”

Beneficial effects of acetyl-DL-Leucine (ADLL) in a mouse model of Sandhoff disease by Kaya, E, Smith, D, Smith, C, Boland, B, Strupp , M, Platt, F

“…Here, we explored the efficacy of acetyl-DL-leucine (ADLL), which has been shown to improve ataxia in observational studies in patients with Niemann–Pick Type C1 and other cerebellar ataxias. …”

Early increase in the neuronal marker N-acetyl-aspartate with antidepressant treatment of major depression by Taylor, M, Godlewska, B, Norbury, R, Selvaraj, S, Near, J, Cowen, P

Cohesin's DNA exit gate is distinct from its entrance gate and is regulated by acetylation. by Chan, K, Roig, M, Hu, B, Beckouët, F, Metson, J, Nasmyth, K

“…According to this notion, the function of Smc3 acetylation is to block its dissociation from α-kleisin. …”

Influence of Hydrophobicity of Acetylated Nanocellulose on the Mechanical Performance of Nitrile Butadiene Rubber (NBR) Composites by Taib, Mohamad Nurul Azman Mohammad, Yehye, Wageeh Abdulhadi, Julkapli, Nurhidayatullaili Muhd, Hamid, Sharifah Bee Abd

“…The Fourier transform infra-red (FTIR) showed the existent of acetyl groups on surface of the NCC after treatment by existent of the peak 1736 cm-1 that attributed to carbonyl groups some peaks were observed at 1430, 1361 and 1248 cm-1 and confirmed on the acetylation process. …”

Bis(2-acetyl-5-hydroxyphenolato-κ2O,O′)copper(II) by Ali, Hapipah Mohd, Ng, S.W., Halim, S.N.A.

Glycerol acetylation into acetins over SnO2-based bimetallic oxide catalyst by Azami, Ain Arisya, Ramli, Irmawati, Mohamad Rasid, Shera Farisya, Khairul Lail, Muhammad Shamirul, Zakaria, Mohd Rafein, Iqbal, Sarwat

“…These catalysts were tested for the acetylation of glycerol to monoacetin (MA), diacetin (DA) and triacetin (TA) in a batch reactor at a molar ratio of glycerol: acetic acid of 1:6 w/v, a temperature of 100°C, a reaction time of 2 h and a catalyst loading of 0.5 g. …”
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Entamoeba histolytica acetyl-CoA synthetase: biomarker of acute amoebic liver abscess by Lim, Boon Huat, Alfonso, Olivos Garcia, Tan, Zi Ning, Wong, Weng Kin, Noordin, Rahmah, Anaqi Azham, Siti Shafiqah, Lee, Zhi Jie, Guee, Cher Ching, Foo, Phiaw Chong, Pim, Chau Dam

“…Objective: To characterize the Entamoeba histolytica (E. histolytica) antigen(moribound amoebic liver abscess hamsters. s) recognized by Methods: Crude soluble antigen of E. histolytica was probed with sera of moribund hamsters isnp e1cDtr-o manedtr y2 Da-naWlyessitse.r nT hbel octo arrneaslpyosnesd.i nTgh eg eannet iwgeansi cc lopnroetde iann wd aesx pthreenss esden itn f oErs ctahnerdiecmhi am caoslsi BprLo2t1e-inA.I to produce the recombinant E. histolytica ADP-forming acetyl-CoA synthetase (EhACS) recombinAa nctu psrtootmeiins.ed ELISA was developed to evaluate the sensitivity and specificity of the Results: A ~75 kDa protein band with a pI value of 5.91-6.5 was found to be antigenic; and not dtheete pctreodte biny tsoe rbae o tfh hea 7m7s tkeDrsa iEn . thheis tcoolnyttricoal gAroDuPp-. fToramndinegm amceatsysl -spCeocAt rsoymnetthreyt aasnea l(yEshisA rCeSv)e. aTlhede icnufsetcotmedi s(end= 3E1L) aISnAd croensutrlotsl grreovuepa lheadm 1s0te0r%s (sne=n5s)i stievriutym asnadm p10le0s%, rsepsepceicftiicvietyly .w hen tested against Conclusions: This finding suggested the significant role of EhACS as a biomarker for moribund shtaumdisetse resx pwliothre athcue tpeo atemnotieabl irco lleivs eorf aEbhsAcCeSss i n(A bLeAtt)e rin ufnecdteirosnta. nItd iinsg d teheem peadth pogeertnineseinst o tfh AaLt Afu; taunrde in the development of vaccine and diagnostic tests to control ALA in human populations.…”

Effect of Acetyl Group on Mechanical Properties of Chitin/Chitosan Nanocrystal: A Molecular Dynamics Study by Cui, Junhe, Yu, Zechuan, Lau, Denvid

“…In order to understand how the acetyl group enhances the fracture resistance capability of chitin fiber, we constructed atomistic models of chitin with varied acetylation degree and analyzed the hydrogen bonding pattern, fracture, and stress-strain behavior of these models. …”
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Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase by Cohen, Steven E, Can, Mehmet, Wittenborn, Elizabeth C, Hendrickson, Rachel A, Ragsdale, Stephen W, Drennan, Catherine L

“…The Wood-Ljungdahl pathway allows for autotrophic bacterial growth on carbon dioxide, with the last step in acetyl-CoA synthesis catalyzed by the bifunctional enzyme carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS). …”
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Constructing an ethanol utilization pathway in Escherichia coli to produce acetyl-CoA derived compounds by Liang, Hong, Ma, Xiaoqiang, Ning, Wenbo, Liu, Yurou, Sinskey, Anthony J, Stephanopoulos, Gregory, Zhou, Kang

“…This EUP can convert ethanol into acetyl-CoA without ATP consumption, and generate two molecules of NADH per molecule of ethanol. …”
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Constructing an ethanol utilization pathway in Escherichia coli to produce acetyl-CoA derived compounds by Liang, Hong, Ma, Xiaoqiang, Ning, Wenbo, Liu, Yurou, Sinksey, Anthony J., Stephanopoulos, Gregory, Zhou, Kang

“…This EUP can convert ethanol into acetyl-CoA without ATP consumption, and generate two molecules of NADH per molecule of ethanol. …”
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Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival by Yi, Caroline H., Pan, Heling, Seebacher, Jan, Jang, Il-Ho, Hyberts, Sven G., Heffron, Gregory J., Vander Heiden, Matthew G., Yang, Renliang, Li, Fupeng, Locasale, Jason W., Sharfi, Hadar, Zhai, Bo, Rodriguez-Mias, Ricard, Luithardt, Harry, Cantley, Lewis C., Daley, George Q., Asara, John M., Gygi, Steven P., Wagner, Gerhard, Liu, Chuan-Fa, Yuan, Junying

“…Here, we describe a biochemical assay to detect the acetylation status of proteins and demonstrate that protein N-alpha-acetylation is regulated by the availability of acetyl-CoA. …”
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Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus by Chaudhary, Deepika, Singh, Avantika, Marzuki, Mardiana, Ghosh, Abhirupa, Kidwai, Saqib, Gosain, Tannu Priya, Chawla, Kiran, Gupta, Sonu Kumar, Agarwal, Nisheeth, Saha, Sudipto, Kumar, Yashwant, Thakur, Krishan Gopal, Singhal, Amit, Singh, Ramandeep

“…We have determined steady state kinetic parameters for the acetylation of L-homoserine by Rv3341. We show that the recombinant enzyme followed Michaelis-Menten kinetics and utilizes both acetyl-CoA and propionyl-CoA as acyl-donors. …”
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Histone 4 lysine 8 acetylation regulates proliferation and host–pathogen interaction in Plasmodium falciparum by Gupta, Archana P., Zhu, Lei, Tripathi, Jaishree, Kucharski, Michal, Patra, Alok, Bozdech, Zbynek

“…Results: Using a dominant-negative transgenic approach, we showed that acetylations of histone H4 play a direct role in transcription. …”
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CYCLISATION-ACETYLATION KINETICOF (R)-(+)-CITRONELLAL BY Zn2+-NATURAL ZEOLITE AS SOLID SOLVENT CATALYST by Perpustakaan UGM, i-lib

“…ABSTRACT Kinetic in cyc/isation-acetylation of (R)-(+)-citronellal with acetic anhydride was investigated over Zn2+_ Natural zeolite (Zn2+-Natzeo)as a catalyst. …”

A multifunctional acetyl-CoA carboxylase gene confers freesing tolerance in arabidopsis thaliana by Amid, Azura, Warren, Garreth J.

“…Through mapping, sequencing and transgenic complementation, sfr3-1 was revealed as a missense mutation in ACC1, which is an essential gene encoding multifunctional acetyl-CoA carboxylase. Suppression of ACC1 expression by RNA interference produced a freezing-sensitive phenotype with some similarity to that of sfr3-1. …”
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Acetylation and phosphorylation control both local and global stability of the chloroplast F1 ATP synthase. by Schmidt, C, Beilsten-Edmands, V, Mohammed, S, Robinson, C

“…We identified multiple phosphorylation and acetylation sites and found that both modifications stabilise binding of ε and δ subunits. …”

The Interaction of Alba, a Conserved Archaeal Chromatin Protein, with Sir2 and Its Regulation by Acetylation by Bell, S