Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation. by Corre, S, Primot, A, Baron, Y, Le Seyec, J, Goding, C, Galibert, MD

“…Here we show that, in response to DNA damage, oxidative stress and cellular infection USF-1 is acetylated in a phospho-Thr-153-dependent fashion. Phospho-acetylated USF-1 is nuclear and interacts with DNA but displays altered gene regulatory properties. …”

CBP/p300 bromodomains regulate amyloid-like protein aggregation upon aberrant lysine acetylation by Olzscha, H, Fedorov, O, Kessler, B, Knapp, S, La Thangue, N

“…Lysine acetylation is becoming increasingly recognized as a general biological principle in cellular homeostasis, and is subject to abnormal control in different human pathologies. …”

2,5-Di-O-acetyl-3-C-methyl-D-lyxono-1,4-lactone by Bream, R, Watkin, D, Soengas, R, Eastwick-Field, V, Fleet, G

Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration. by Arbely, E, Natan, E, Brandt, T, Allen, MD, Veprintsev, D, Robinson, C, Chin, J, Joerger, A, Fersht, A

“…Lys120 in the DNA-binding domain (DBD) of p53 becomes acetylated in response to DNA damage. But, the role and effects of acetylation are obscure. …”

Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster. by Anguita, E, Johnson, C, Wood, W, Turner, B, Higgs, D

“…We have analyzed the pattern of core histone acetylation across 250 kb of the telomeric region of the short arm of human chromosome 16. …”

MRS reveals additional hexose N-acetyl resonances in the brain of a mouse model for Sandhoff disease. by Lowe, J, Stuckey, D, Awan, F, Jeyakumar, M, Neville, D, Platt, F, Griffin, J, Styles, P, Blamire, A, Sibson, N

“…Sandhoff disease, one of several related lysosomal storage disorders, results from the build up of N-acetyl-containing glycosphingolipids in the brain and is caused by mutations in the genes encoding the hexosaminidase beta-subunit. …”

Assessment on the Effect of Sulfuric Acid Concentration on Physicochemical Properties of Sulfated-Titania Catalyst and Glycerol Acetylation Performance by Mohamad Rasid Shera Farisya, Ramli Irmawati, Ishak Nor Shafizah, Yap, Taufiq Yun Hin, Ernee Noryana Muhamad, Siew, Ling Lee, Nurrulhidayah Salamun

“…The synthesized catalysts were tested on glycerol acetylation reaction at conditions: 0.5 g catalyst loading, 100–120 ◦C temperature, 1:6 glycerol/acetic acid molar ratios, and 2–4 h reaction time. …”
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Synthesis and characterization of sulfonated carbon catalysts derived from biomass waste and its evaluation in glycerol acetylation by Nda-Umar, Usman Idris, Ramli, Irmawati, Muhamad, Ernee Noryana, Azri, Norsahida

“…The synthesized acid catalysts were evaluated in glycerol acetylation with acetic acid (molar ratio 1:6) in a batch liquid phase reaction under atmospheric pressure at 120 °C, 450 rpm for 1 h, 3 h, and 5 h respectively. …”

Acetylation of glycerol over carbon supported yttrium oxide catalysts and optimization analysis by response surface methodology by Amadi, Uchenna Fidelis

“…The use of homogeneous catalysts in glycerol acetylation have been associated with several shortcomings hence the growing interest in the use of heterogeneous catalysts such as metal oxide. …”
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Assessment on the effect of sulfuric acid concentration on physicochemical properties of sulfated-titania catalyst and glycerol acetylation performance by Mohamad Rasid, Shera Farisya, Ramli, Irmawati, Ishak, Nor Shafizah, Yap, Taufiq Yun Hin, Muhamad, Ernee Noryana, Lee, Siew Ling, Salamun, Nurrulhidayah

“…The synthesized catalysts were tested on glycerol acetylation reaction at conditions: 0.5 g catalyst loading, 100–120 °C temperature, 1:6 glycerol/acetic acid molar ratios, and 2–4 h reaction time. …”

Genome-Wide Profiling of H3K56 Acetylation and Transcription Factor Binding Sites in Human Adipocytes by Lo, Kinyui Alice, Bauchmann, Mary K., Baumann, Amy P., Donahue, Christopher J., Thiede, Mark A., Hayes, Lisa S., Des Etages, Shelley Ann G., Fraenkel, Ernest

“…In this study, we identified H3K56 acetylation sites in human adipocytes derived from mesenchymal stem cells. …”
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Molecular dynamics simulations demonstrate the regulation of DNA-DNA attraction by H4 histone tail acetylations and mutations by Korolev, Nikolay, Yu, Hang, Lyubartsev, Alexander P., Nordenskiöld, Lars

“…The H4 tail a. a. fragment GGAKRHRK as well as the H4 Lys16 acetylated fragment are highly flexible. The present work allows capturing typical features of the histone tail-counterion-DNA structure, interaction and dynamics.…”
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Copper and secondary amine‐catalyzed pyridine synthesis from o‐acetyl oximes and α,β-unsaturated aldehydes by Tan, Wei Wen, Wu, Bin, Wei, Ye, Yoshikai, Naohiko

“…A. Acetophenone O-acetyl oxime (1). A 250-mL, two-necked roundbottomed flask equipped with a Teflon-coated magnetic stir bar (oval, 20 x 10 mm) is charged with acetophenone (9.33 mL, 80.0 mmol, 1 equiv) (Note 2), pyridine (18 mL, 223 mmol, 2.8 equiv) (Note 3), ethanol (40 mL) (Note 4), and hydroxylamine hydrochloride (8.33 g, 120 mmol, 1.5 equiv) (Note 5). …”
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Comprehensive mapping of post-translational modifications of progesterone receptor (PR) and functional analysis of novel methylation and acetylation of PR. by Chung, Hwa Hwa.

“…K183 is identified as a novel acetylation site of PR by LC/MS/MS. Mutagenesis studies verified that K183 is the primary site of acetylation. …”
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Pengaruh pemberian N-Acetyl Cystein (NAC) dalam mencegah hipertensi dalam kehamilan menjadi preeklamsia berat by , DEVI, Adhitya Maharani, , Prof.Dr. H.M. Sulchan Sofoewan, PhD.,SpOG(K)

THE RELATIONSHIP OF ARGYROPHILIC PLAQUES AND NEUROFIBRILLARY TANGLES TO THE SEVERITY OF DEMENTIA AND CORTICAL CHOLINE ACETYL TRANSFERASE LEVELS IN ALZHEIMERS-DISEASE by Wilcock, G, Esiri, M, Bowen, D

Inhibition of endothelial NOTCH1 signaling attenuates inflammation by reducing cytokine-mediated histone acetylation at inflammatory enhancers by Poulsen, L, Edelmann, R, Krüger, S, Diéguez-Hurtado, R, Shah, A, Stav-Noraas, T, Renzi, A, Szymanska, M, Wang, J, Ehling, M, Benedito, R, Kasprzycka, M, Bækkevold, E, Sundnes, O, Midwood, K, Scott, H, Collas, P, Siebel, C, Adams, R, Haraldsen, G, Sundlisæter, E, Hol, J

“…<strong>Approach and Results—</strong>Observing that Cre/Lox-induced conditional mutations of endothelial Notch modulated inflammation in murine contact hypersensitivity, we found that IL (interleukin)-1β stimulation induced rapid recruitment of RELA to genomic sites occupied by NOTCH1-RBPJ and that NOTCH1 knockdown reduced H3K27 acetylation at a subset of NF-κB–directed inflammatory enhancers. …”

Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases. by Crabtree, MD, Fletcher, C, Churchman, M, Hodgson, S, Neale, K, Phillips, R, Tomlinson, I

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP. by Mantovani, F, Tocco, F, Girardini, J, Smith, P, Gasco, M, Lu, X, Crook, T, Del Sal, G

“…In addition, Pin1 is recruited to chromatin by p53 and stimulates binding of the p300 acetyltransferase and consequent p53 acetylation. Accordingly, tumor-associated mutations at Pin1-binding residues within the p53 proline-rich domain hamper acetylation of p53 by p300. …”

Structural and biochemical analyses reveal how ornithine acetyl transferase binds acidic and basic amino acid substrates. by Iqbal, A, Clifton, I, Chowdhury, R, Ivison, D, Domene, C, Schofield, C

“…Structural and biochemical analyses reveal how ornithine acetyl-transferases catalyse the reversible transfer of an acetyl-group from a basic (ornithine) to an acidic (glutamate) amino acid by employing a common mechanism involving an acetyl-enzyme intermediate but using different side chain binding modes.…”