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Acetylcholinesterase Inhibitors in the Treatment of Neurodegenerative Diseases and the Role of Acetylcholinesterase in their Pathogenesis
Published 2021-08-01Subjects: “…acetylcholinesterase…”
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Human brain acetylcholinesterase
Published 1993“…<p>Procedures for the preparative purification of human acetylcholinesterase (AChE; EC 3.1.1.7) have been examined. …”
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Hyperchaos in acetylcholinesterase enzyme systems
Published 1997“…Burst generation via a complex bifurcation scenario is discussed using a two compartments model of an enzyme system with substrate inhibition kinetics affected by the production of hydrogen ions accompanying the reaction (e.g. acetylcholinesterase enzyme system). Evidences are given to support the existence of homoclinicity associated with this complex dynamics, including the generalised criterion developed by Rossler et al. [1] for the application of Sil'nikov's theorem in the case of four-dimensional systems. …”
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Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid-β Aggregation and Acetylcholinesterase-Amyloid Interaction
Published 2022-10-01“…One of the pathological hallmarks of Alzheimer’s disease (AD) is the formation of amyloid-β plaques. Since acetylcholinesterase (AChE) promotes the formation of such plaques, the inhibition of this enzyme could slow down the progression of amyloid-β aggregation, hence being complementary to the palliative treatment of cholinergic decline. …”
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Synthesis of Novel Chalcones as Acetylcholinesterase Inhibitors
Published 2016-07-01Subjects: Get full text
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Inhibition of Acetylcholinesterase by Novel Lupinine Derivatives
Published 2023-04-01Subjects: “…acetylcholinesterase…”
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Altered levels of acetylcholinesterase in Alzheimer plasma.
Published 2010-01-01“…BACKGROUND: Many studies have been conducted in an extensive effort to identify alterations in blood cholinesterase levels as a consequence of disease, including the analysis of acetylcholinesterase (AChE) in plasma. Conventional assays using selective cholinesterase inhibitors have not been particularly successful as excess amounts of butyrylcholinesterase (BuChE) pose a major problem. …”
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Amperometric acetylcholinesterase biosensor for physostigmine determination
Published 2018-03-01Subjects: “…acetylcholinesterase…”
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Acetylcholinesterase: Old Questions and New Developments
Published 2013-01-01Subjects: “…Acetylcholinesterase…”
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In vitro inhibition of acetylcholinesterase by acephate and methamidophos
Published 1990“…Inhibition of the acetylcholinesterase (AChE) of two insects, laboratory rat and human by acephate and methamidophos insecticides was evaluated in vitro. …”
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Acetylcholinesterase, Specific Acetylcholinesterase and Total Protein Concentrations in the Brain Regions of Broiler Chickens Fed Dietary Monosodium Glutamate
Published 2019-06-01“…The study was carried out to examine the effect of varied levels of dietary monosodium glutamate on acetylcholinesterase, specific acetylcholinesterase and total protein concentrations in the brain regions of broiler chickens. …”
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A peptide derived from the C-terminal region of acetylcholinesterase modulates extracellular concentrations of acetylcholinesterase in the rat substantia nigra.
Published 2004“…It is well established that acetylcholinesterase (AChE) has 'non-classical' functions independent of cholinergic transmission. …”
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In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase
Published 2020-07-01Subjects: Get full text
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Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition
Published 2023-10-01Subjects: Get full text
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Acetylcholinesterase of Schistosoma mansoni: an antigen of functional implications
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Why is Aged Acetylcholinesterase So Difficult to Reactivate?
Published 2017-09-01Subjects: “…acetylcholinesterase…”
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Presenilin 1 Modulates Acetylcholinesterase Trafficking and Maturation
Published 2023-01-01Subjects: Get full text
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Biocomputational Screening of Natural Compounds against Acetylcholinesterase
Published 2021-04-01“…However, there is currently no treatment for AD, as most drug-like compounds have failed in clinical trials. Acetylcholinesterase (AChE) is the target of most drugs used commercially to treat AD. …”
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Is red cell acetylcholinesterase related with arterial hypertension?
Published 1986-02-01Get full text
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A photopharmocology study with photoswitchable acetylcholinesterase inhibitors
Published 2018“…It is breakdown by acetylcholinesterase (AChE) enzymes into acetate and choline. …”
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Final Year Project (FYP)