Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Molecular Mechanism of Triptolide in the Treatment of Membranous Nephropathy by Zhang PN, Tang JY, Yang KZ, Zheng QY, Dong ZC, Geng YL, Liu YN, Liu WJ

“…Ping Na Zhang,1,* Jing Yi Tang,1,* Ke Zhen Yang,2,* Qi Yan Zheng,1 Zhao Cheng Dong,1 Yun Ling Geng,1 Yu Ning Liu,1 Wei Jing Liu1 1Renal Research Institution of Beijing University of Chinese Medicine, and Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu Ning Liu; Wei Jing Liu, Renal Research Institution of Beijing University of Chinese Medicine, and Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, People’s Republic of China, Tel/Fax +86-10-84013190, Email liuyn2021@126.com; liuweijing-1977@hotmail.comBackground: Triptolide, a major active ingredient isolated from Tripterygium wilfordii Hook f., is effective in the treatment of membranous nephropathy (MN); however, its pharmacological mechanism of action has not yet been clarified. …”
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A Systematic Review and Meta-Analysis Protocol on How Best to Use Non-Pharmacologic Therapies to Manage Chronic Low Back Pain and Associated Depression by Guo Y, Ma Q, Zhou X, Yang J, He K, Shen L, Zhao C, Chen Z, Tan CIC, Chen J

“…Yu Guo,1,* Qingyu Ma,1,* Xuan Zhou,1 Juan Yang,2 Kejie He,3 Longbin Shen,4 Canghuan Zhao,3 Zhuoming Chen,4 Celia Ia Choo Tan,5 Jiaxu Chen1 1Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Jinan University, Guangzhou City, People’s Republic of China; 2Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA; 3Department of Acupuncture, First Affiliated Hospital of Jinan University, Guangzhou City, People’s Republic of China; 4Rehabilitation Medicine Center, First Affiliated Hospital of Jinan University, Guangzhou City, People’s Republic of China; 5Department of Physiotherapy, Singapore General Hospital, Singapore, Singapore*These authors contributed equally to this workCorrespondence: Jiaxu Chen, Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Jinan University, No. 601 Huangpu Road West, Tianhe District, Guangzhou City, People’s Republic of China, Email chenjiaxu@hotmail.comPurpose: To evaluate the efficacy of different non-pharmacologic therapies (NPTs) on relieving depressive symptoms and pain intensity in individuals living with chronic low back pain (LBP) and associated depression.Methods: A comprehensive search of seven English databases and two Chinese databases from inception to the search date will be undertaken. …”
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Electroacupuncture inhibits dendritic spine remodeling through the srGAP3-Rac1 signaling pathway in rats with SNL by Qiaoyun Wu, Chenchen Cai, Xinwang Ying, Yujun Zheng, Jiaying Yu, Xiaoxue Gu, Wenzhan Tu, Xinfa Lou, Guanhu Yang, Ming Li, Songhe Jiang

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The effect of robot-assisted gait training for patients with spinal cord injury: a systematic review and meta-analysis by Luo Bin, Xiaoping Wang, Hu Jiatong, Fan Donghua, Wang Qiang, Shen Yingchao, Miao Yiming, Ma Yong, Ma Yong

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Panax notoginseng saponins promotes cerebral recovery from ischemic injury by downregulating LINGO-1 and activating the EGFR/PI3K/AKT signaling pathways in vivo by Tiantian Yang, Qi Guo, Xiaowei Shi, Shuang Wu, Ya Li, Yikun Sun, Yizhou Zhao, Limin Chai, Yonghong Gao, Lixia Lou, Bin Dong, Lingqun Zhu

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Hypoglycemic Effect of an Herbal Decoction (Modified Gangsimtang) in a Patient with Severe Type 2 Diabetes Mellitus Refusing Oral Anti-Diabetic Medication: A Case Report by Sungjun Joo, Hyonjun Chun, Jisu Lee, Seungmin Seo, Jungmin Lee, Jungtae Leem

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Comparison of Concordance between Chuna Manual Therapy Diagnostic Methods (Palpation, X-ray, Artificial Intelligence Program) in Lumbar Spine: An Exploratory, Cross-Sectional Clini... by Jin-Hyun Lee, Hyeonjun Woo, Jun-Su Jang, Joong Il Kim, Young Cheol Na, Kwang-Ryeol Kim, Eunbyul Cho, Jung-Han Lee, Tae-Yong Park

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The Effect of 3-Liver Pressure Point on Postpartum Severity of Pain: randomized clinical trial by Mahdieh Abouei Mehrizi, Reza Heshmat, Parisa Reza Nezhad, Malihe Nasiri, Afsar Tabatabaie Bafghi, Atiyeh Javaheri, Giti Ozgoli

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Effects of electroacupuncture on the kisspeptin-gonadotropin-releasing hormone (GnRH) /luteinizing hormone (LH) neural circuit abnormalities and androgen receptor expression of kis... by Ge Xu, Xuedan Zhao, Zhihao Li, Junwei Hu, Xu Li, Juanjuan Li, Yuelai Chen

“…Thus, the results provide an experimental basis for acupuncture as an adjuvant medical therapy on PCOS.…”
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Emotional freedom technique versus written exposure therapy versus waiting list for post-traumatic stress disorder: protocol for a randomised clinical MRI study by Hyungjun Kim, Yujin Choi, Yunna Kim, Sunyoung Choi, Young-Eun Choi, Ojin Kwon, Do-Hyung Kwon, Seung-Ho Lee, Seung-Hun Cho

“…Introduction The emotional freedom technique (EFT) is an acupuncture-based psychotherapy that combines tapping on acupoints with cognitive reframing. …”
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Prediction Score for Clinical Outcome of Chinese Patients with Cerebral Venous Thrombosis by Li M, Zhang B, Xie J, Meng R, Ji X

“…Min Li,1,2,* Binlong Zhang,3,* Jiangbo Xie,4 Ran Meng,1,2 Xunming Ji2,5 1Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing Institute for Brain Disorders, Capital Medical University, Beijing, People’s Republic of China; 3Department of Acupuncture, Moxibustion, and Neurology, Guang’anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 4Department of Neurology, Weifang Traditional Chinese Hospital, Weifang, Shandong, People’s Republic of China; 5Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ran Meng, Department of Neurology, Xuanwu Hospital, Capital Medical University, 45 Changchun Road, Xicheng District, Beijing, 100053, People’s Republic of China, Tel +86-13693080599, Email ranmeng2011@126.com Xunming Ji, Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Road, Xicheng District, Beijing, 100053, People’s Republic of China, Tel +86-13911077166, Email jixm@ccmu.edu.cnBackground: Although numerous prognostic markers for cerebral venous thrombosis (CVT) have been reported, inconsistencies exist in their predictive values, leading to contradictory forecasts. …”
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Short-term efficacy of non-pharmacological interventions for global population with elevated blood pressure: A network meta-analysis by Taihang Shao, Leyi Liang, Chengchao Zhou, Yaqian Tang, Wenqing Gao, Yusi Tu, Yue Yin, Daniel C. Malone, Wenxi Tang, Wenxi Tang

“…For DBP, relaxation was the most advantageous intervention group when compared with usual care (mean difference = −4.99 mmHg, 95% CI −7.03 to −2.96), and acupuncture, meditation, and combination exercise were the three most effective specific interventions. …”
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Efficacy and Mechanism of Action of Wuyintiaoshen Therapy in Patients with Post-stroke Insomnia by Chenchen GUO, Haifeng LU, He ZHUANG, Li LI, Congan WANG, Yi DING

“…Besides usual rehabilitation training and basic medical treatment, experimental group received Wuyintiaoshen therapy〔listening to the music symbolizing the five elements (metal, wood, water, fire, and earth) in Chinese philosophy〕 plus acupuncture treatment with Baihui, Shenting, and Yintang acupoints, and the control group received oral alprazolam before sleeping. …”
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Effect of "Iran's Health System Evolution" And "Tariff Change" based on relative values book on Performance of Obstetrics and Gynecology Department: A case study in a Big Hospital by Hosein Ebrahimipour, Samira Olyani, Alireza Rezazadeh, Ali Khorsand Vakilzadeh, Somayeh Fazaeli, Mina Jafari, Arezoo Shabanifar, Mehdi Yousefi

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Acupoint transplantation versus non-acupoint transplantation using autologous peripheral blood mononuclear cells in treating peripheral arterial disease by Wenjing Guo, Ling Pan, Ruiyu Yang, Jiali Sun, Qinglin Hu, Pingping Huang

“…Numerous studies have discussed the therapeutic outcomes of using cell therapy or acupuncture to treat peripheral artery disease (PAD). …”
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Exploring the active ingredients and potential mechanisms of action of sinomenium acutum in the treatment of rheumatoid arthritis based on systems biology and network pharmacology by Nan Gong, Nan Gong, Lin Wang, Lili An, YuanKun Xu, YuanKun Xu

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Preferences for childbirth delivery and pain relief methods among pregnant women in Vietnam by Nguyen, Tham Thi, Nguyen, Long Hoang, Nguyen, Ha Thu Thi, Dam, Vu Anh Trong, Vu, Thuc Minh Thi, Latkin, Carl A., Zhang, Melvyn, Ho, Roger C. M., Ho, Cyrus S. H.

“…Most of the sample did not have any preferences for specific pharmacological pain relief methods (70.1%), while support from partner/relatives was the most preferable non-pharmacological method (61.3%), following by water birth (11.1%) and acupuncture (9.9%). Desire to have another baby, relatives’ experience, selection date of birth, and instrumental social support were major drivers of the cesarean section selection. …”
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Self-reported home exercise adherence – fact or fiction? A validity and reliability study using concealed accelerometry among people with knee osteoarthritis by Nicolson, P, Hinman, R, Wrigley, T, Stratford, P, Bennell, K

“…Sleep interventions were cognitive behavioural therapy (CBT) (n ¼ 8), pillows (n ¼ 4), sleep medication (n ¼ 3), exercise (n ¼ 2), massage (n ¼ 2), music (n ¼ 1), acupuncture (n ¼ 1), and mattresses (n ¼ 1). Intervention periods ranged from four to ten weeks. …”

OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January... by Zhang, W, Nuki, G, Moskowitz, R, Abramson, S, Altman, R, Arden, N, Bierma-Zeinstra, S, Brandt, K, Croft, P, Doherty, M, Dougados, M, Hochberg, M, Hunter, D, Kwoh, K, Lohmander, L, Tugwell, P

“…Among non-pharmacological therapies, ES for pain relief was unchanged for self-management, education, exercise and acupuncture. However, with new evidence the ES for pain relief for weight reduction reached statistical significance, increasing from 0.13 [95% confidence interval (CI) -0.12, 0.36] in 2006 to 0.20 (95% CI 0.00, 0.39) in 2009. …”

The Abuse Potential of Novel Synthetic Phencyclidine Derivative 1-(1-(4-Fluorophenyl)Cyclohexyl)Piperidine (4′-F-PCP) in Rodents by In Soo Ryu, Oc-Hee Kim, Young Eun Lee, Ji Sun Kim, Zhan-Hui Li, Tae Wan Kim, Ri-Na Lim, Young Ju Lee, Jae Hoon Cheong, Hee Jin Kim, Yong Sup Lee, Scott C. Steffensen, Bong Hyo Lee, Joung-Wook Seo, Eun Young Jang

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