Acute promyelocytic leukemia : molecular genetics, mouse models and targeted therapy / by Pandolfi, Pier Paolo, Vogt, P. K. (Peter K.), 1932-

Acute promyelocytic leukemia : [electronic resorces] molecular genetics, mouse models and targeted therapy by Pandolfi, Pier Paolo, Vogt, Peter K., SpringerLink (Online service)

Get full text

A Case of T-Cell Acute Lymphoblastic Leukemia after Treatment of Acute Promyelocytic Leukemia by Bee, P.C., Gan, G.G., Sangkar, J.V., Teh, A., Goh, K.Y.

“…We diagnosed T-cell acute lymphoblastic leukemia (T-ALL) with multiple cytogenetic abnormalities in a 17-year-old girl a year after she had received a diagnosis of acute promyelocytic leukemia (APML). After the diagnosis of APML in June 2001, the patient was treated with idarubicin and all-trans-retinoic acid. …”

Myeloid Sarcoma: An Unusual Presentation of Acute Promyelocytic Leukemia Causing Spinal Cord Compression by Kyaw, T.Z., Maniam, J.A.S., Bee, P.C., Chin, E.F., Nadarajan, V.S., Shanmugam, H., Abd Kadir, K.A.

“…Acute promyelocytic leukemia with concurrent myeloid sarcoma is a rare clinical event. …”

Cytotoxic effects of commercial wheatgrass and fiber towards human acute promyelocytic leukemia cells (HL60). by Mohamed Alitheen, Noorjahan Banu, Chuah , Li Oon, Yeap, Swee Keong, Tan, Kee Chuan, Ho, Ket Li, Ho, Wan Yong

Get full text

Myocardial infarction with intracardiac thrombosis as the presentation of acute promyelocytic leukemia: diagnosis and follow-up by cardiac magnetic resonance imaging. by Cahill, T, Chowdhury, O, Myerson, S, Ormerod, O, Herring, N, Grimwade, D, Littlewood, T, Peniket, A

Blumea balsamifera (L.) DC. elicit anti-kinase, anti-phosphatase and cytotoxic activities against acute promyelocytic leukemia cells (HL-60) by Nurul A. Ismail, Azlinah Matawali, Lee, Ping Chin, How, Siew-Eng, Lee, Boon H., Goh, Lucky Poh Wah, Jualang Azlan Gansau

“…These substances have the potential to be used as treatment agent for acute promyelocytic leukemia.…”
Get full text
Get full text

Attenuated arsenic trioxide plus ATRA therapy for newly diagnosed and relapsed APL: Long-term follow-up of the AML17 trial by Russell, N, Burnett, A, Hills, R, Betteridge, S, Dennis, M, Jovanovic, J, Dillon, R, Grimwade, D

“…We have previously reported on the results of the United Kingdom National Cancer Research Institute (NCRI) AML17 trial, which, for acute promyelocytic leukemia (APL) of all risk groups, compared anthracycline + all-trans retinoic acid (ATRA) (AIDA) vs arsenic trioxide (ATO) + ATRA using an attenuated schedule of ATO.1 Here, we present long-term survival results for randomized patients and for 32 patients who received the same schedule of ATO + ATRA after relapsing from the AIDA arm.…”

Bioassay-guided isolation and identification of antimicrobial and cytotoxic compounds from the leaves of Muntingia calabura / Adila Sahida Sufian by Sufian, Adila Sahida

“…MCEA, which appeared to be the most active extract against MSS A (S. aureus 25923) (MIC - 125 μg/mL) and HL60 cell line (human acute promyelocytic leukemia) (IC50 = 17.26 μg/mL), was further fractionated using vacuum liquid chromatography (VLC) to afford seven fractions (F1-F7).…”
Get full text

Assessment of minimal residual disease in acute myeloid leukemia. by Grimwade, D, Vyas, P, Freeman, S

“…Moreover, sequential MRD monitoring using an internationally standardized PML-RARA RQ-PCR assay has been successfully used to guide molecularly targeted therapy in acute promyelocytic leukemia (APL). There have also been significant advances in multiparameter flow cytometry (MFC) to detect MRD, with introduction of 6-10 color technology and improved understanding of the immunophenotype of leukemic stem cells. …”

Arsenic trioxide rescues structural p53 mutations through a cryptic allosteric site by Chen, S, Wu, J-L, Liang, Y, Tang, Y-G, Song, H-X, Wu, L-L, Xing, Y-F, Yan, N, Li, Y-T, Wang, Z-Y, Xiao, S-J, Lu, X, Chen, S-J, Lu, M

“…Here we report the identification of small molecules, including arsenic trioxide (ATO), an established agent in treating acute promyelocytic leukemia, as cysteine-reactive compounds that rescue structural p53 mutations. …”

Advances in malignant hematology / by Saba, Hussain I. 536043, Mufti, G. J. 536044

Genome-wide analysis for genomic alteration in acute promyelocytic leukaemia by Hassan, Rosline

“…Acute Promyelocytic Leukemia (APL) is a subset of acute myeloid leukemias (AML), and is commonly associated with the presence of chromosomal translocations leading to the expression of the PML-RARA fusion protein. …”
Get full text

Effects of Damnacanthal, Nordamnacanthal, Betulinic Acid and Zerumbone Isolated from Local Medicinal Plants on Leukemia Cell Lines and Immune Cells by Abd Rahman, Mashitoh

“…Toxicity study was performed on HL-60 (Human acute promyelocytic leukemia), CEM-SS (Human T-lymphoblastic leukemia), WEHI-3B (Mouse myelomonocyte leukemia), 3T3 (Mouse embryo fibroblast) and human peripheral blood mononuclear cell (PBMC) by using MTT assay and cell cycle analysis. …”
Get full text

Green synthesis, characterization, and anticancer activity of hyaluronan/zinc oxide nanocomposites by Namvar, Farideh, Azizi, Susan, Rahman, Heshu Sulaiman, Mohamad, Rosfarizan, Rasedee, Abdullah, Soltani, Mozhgan, Abdul Rahim, Raha

“…In the cytotoxicity study, cancer cells, pancreatic adenocarcinoma (PANC-1), ovarian adenocarcinoma (CaOV-3), colonic adenocarcinoma (COLO205), and acute promyelocytic leukemia (HL-60) cells were treated with HA/ZnO nanocomposite. …”
Get full text