Electron spin resonance evidence for electro-generated hydroxyl radicals by Pei, Shuzhao, You, Shijie, Ma, Jun, Chen, Xiaodong, Ren, Nanqi

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Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity by Davey, Curt Alexander, Adhireksan, Zenita, Davey, Gabriela E., Campomanes, Pablo, Groessl, Michael, Clavel, Catherine M., Yu, Haojie, Nazarov, Alexey A., Yeo, Charmian Hui Fang, Ang, Wee Han, Dröge, Peter, Rothlisberger, Ursula, Dyson, Paul J.

“…Here we study two prototypical ruthenium-arene agents—the cytotoxic antiprimary tumour compound [(η6-p-cymene)Ru(ethylene-diamine)Cl]PF6 and the relatively non-cytotoxic antimetastasis compound [(η6-p-cymene)Ru(1,3,5-triaza-7-phosphaadamantane)Cl2]—and discover that the former targets the DNA of chromatin, while the latter preferentially forms adducts on the histone proteins. Using a novel ‘atom-to-cell’ approach, we establish the basis for the surprisingly site-selective adduct formation behaviour and distinct cellular impact of these two chemically similar anticancer agents, which suggests that the cytotoxic effects arise largely from DNA lesions, whereas the protein adducts may be linked to the other therapeutic activities. …”
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Alkaline earth complexes supported by chelating diamido ligands by Haynes, M

“…These were compared with a series of THF adducts characterised in collaboration with Prof. …”

Systematic Studies on the Chelating Ligand Effects of Novel Borafluoronium Ions by Allen, Marissa D.

“…Further investigations into the coordination of other bisphosphine ligands, such as dppe, rac-BINAP, and Xantphos, resulted in the formation of Lewis adducts rather than the desired borafluoronium ions. …”
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Molecular recognition in protein-DNA assemblies by Davey, Curt Alexander

“…Although DNA sequence seemed to dominate site preference, histone octamer association was capable of modulating adduct formation by both inhibiting or promoting platination at certain sites. …”
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An unusual [4 + 4] cycloadduct from an o-quinodimethane : characterisation and computational studies by Mohamed Husaini Abdul Rahman, Ramabhadran, Raghunath O., Collier, Steven J., Storr, Richard C., Bates, Roderick Wayland

“…Trapping of a pyrimidinone-derived o-quinodimethane with tetraphenylcyclopentadienone gives a mixture of the [4 + 2] and formal [4 + 4] adducts. Computational studies show that the latter arises by a sequence of [4 + 2] cycloaddition, homolysis, radical recombination to a spiro-tetrahydrofuran and Claisen rearrangement under the thermolytic conditions.…”
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GROUP III permethylindenyl-phenoxy complexes for biorenewable polymer synthesis by Hayden, JA

“…Coordination complexes of 4-coodinate PHENI* scandium monomer adducts of <em>L</em>-lactide, ϵ-caprolactone, and ω-pentadecalactone are discussed.…”

Synthesis, structural studies and ligand influence on the stability of aryl-NHC stabilised trimethylaluminium complexes by Wu, Melissa M., Gill, Arran M., Lu, Yunpeng, Laura, Falivene, Li, Yongxin, Rakesh, Ganguly, Luigi, Cavallo, Felipe, García

“…Treatment of a series of aromatic NHCs (IMes, SIMes, IPr and SIPr) with trimethylaluminium produced their corresponding Lewis acid–base adducts: IMes·AlMe3 (1), SIMes·AlMe3 (2), IPr·AlMe3 (3), and SIPr·AlMe3 (4). …”
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Asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with α-fluoro-β-keto esters by Yan, Lin, Han, Zhiqiang, Zhu, Bo, Yang, Caiyun, Tan, Choon-Hong, Jiang, Zhiyong

“…A series of important fluorinated adducts, with chiral quaternary carbon centres containing a fluorine atom, was achieved in good yields (up to 93%), with good to excellent enantioselectivities (up to 96% ee) and moderate diastereoselectivities (up to 4:1 dr).…”
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Novel bisisoquinolines : synthesis, resolution and application in asymmetric Henry reaction by Yao, Qiong Ji

“…Application of the enantiopure 1,3- and 1,2-diposed bisisoquinolines in catalysis of asymmetric henry reaction was examined, C1-1’,2’,3’,4’-terahydro-1,1’-bisisoquinoline’s copper(I) complex proved to be the most efficient catalyst for the enantioselective Henry reaction between aldehydes and nitromethane. β-nitroalcohol adducts were obtained in high yields and enatioselectivities. …”
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1,3,2,5-Diazadiborinine featuring nucleophilic and electrophilic boron centres by Wu, Di, Kong, Lingbing, Li, Yongxin, Ganguly, Rakesh, Kinjo, Rei

“…In marked contrast to the reactivity of benzene, borazine, and even azaborinines previously reported, 1,3,2,5-diazadiborinine readily forms the adducts with methyl trifluoromethanesulfonate and phenylacetylene without any catalysts. …”
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Metabolomic characterisation of low-density lipoproteins isolated from iodixanol and KBr-based density gradient ultracentrifugation by Webb, Richard, Lodge, John, Scott, Sophie, Davies, Ian

“…However, in positive mode, non-native brominated adducts were found in LDL isolated using SBUC and evidence of potential bacterial contamination was discovered in samples prepared using IGUC, both of which have the capacity to affect in vitro experiments.…”
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Methyl and dimethyl o-xylenyl-substituted fullerene acceptors for polymer solar cells by Kim, Hee Un, Park, Jong Baek, Grimsdale, Andrew Clive, Hwang, Do-Hoon

“…The lowest unoccupied molecular orbital energy levels increased with increasing number of adducts on the fullerene because of their decreasing number of sp2-hybridized carbons. …”
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Functionalized sp2 carbon-conjugated covalent organic frameworks for interfacial modulation of inverted perovskite solar cells by Abuzeid, Hesham R., Tay, Darrell Jun Jie, Febriansyah, Benny, Kanwat, Anil, Salim, Teddy, Zhumekenov, Ayan A., Pullarkat, Sumod A., Mathews, Nripan

“…Detailed characterization results highlight the role of sp2c-COF in reducing the Ni3+ defect density in NiOx films and forming Lewis acid-base adducts with undercoordinated Pb2+ on the perovskite surfaces, thereby inhibiting interfacial redox reactions and suppressing non-radiative recombination. …”
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Doped amorphous silica nanoparticles as enhancing agents for surface-assisted time-of-flight mass spectrometry by Lim, Angelina Yimei, Gu, Feng, Ma, Zhun, Ma, Jan, Rowell, Frederick

“…Alternatively in the absence of such proton donor/acceptor residues as with hydrophobic particles, the primary ions are released from the particles during desorption and form cation adducts as sodiated and potassiated species in the gas phase above the surface.…”
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Solid-State P NMR, Far-IR, and Structural Studies on Two-Coordinate (Tris(2,4,6-trimethoxyphenyl)phosphine)copper(I) Chloride and Bromide by Bowmaker, Graham A., Cotton, John D., Healy, Peter C., Kildea, John D.

“…The reactions of acetonitrile solutions of copper(I) chloride, CuCl, and copper(I) bromide, CuBr, with the sterically hindered, highly basic tertiary phosphine ligand tris(2,4,6-trimethoxyphenyl)phosphine [=P(2,4,6)3] have been shown to form 1:1 monomeric adducts, [P(2,4,6)3 cux],The two compounds are isomorphous, crystallizing in the tetragonal space group P42. for the chloride, a = 15.237 (4) A, c = 12.373 (3) A, Z = 4, and R = 0.029 for 2339 “observed” (/ > 3<r(/)) reflections, while for the bromide, a - 15.312 (8) A, c = 12.457 (6) A, Z = 4, and R = 0.052 for 2148 “observed” reflections. …”

Self-healing materials for flexible electronic devices by Tiwari, Naveen

“…The composite electrode features a layer of interconnecting AgNWs network on a polyurethane film modified with Diels–Alder adducts (PU-DA). The PU based DA polymeric electrode can heal multiple times due to the presence of DA and retro-DA mechanism, which are based on thermo-reversibility. …”
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Development of hand model and sensor placements for measuring thumb motion by Ong, Di Yong.

“…The aims of this project are to further develop a hand model that includes abduction/adduction of the thumb and to investigate the feasibility of using Optical Linear Encoder (OLE) to detect and measure the abduction/adduction (TMCabd) of the thumb.…”
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Design a partial gravity-balanced upper limb exoskeleton by Tan, Jolyn Chik Ying

“…The unwanted torques added to their joints have caused the patients to have difficulties when doing motions like arm flexion, extension, adduction, abduction and so on. Thus, a passive upper limb exoskeleton that consists of tension springs cable-pulley system is designed to counter the undesirable torques caused by the motors of the active exoskeleton. …”
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Preparation, Structural Analysis, and Reactivity Studies of Phosphenium Dications by Tay, Madelyn Qin Yi, Ilić, Gordana, Werner-Zwanziger, Ulrike, Lu, Yunpeng, Ganguly, Rakesh, Ricard, Louis, Frison, Gilles, Carmichael, Duncan, Vidović, Dragoslav

“…Initial reactivity studies between dications 3a2+/3c2+ and PMe3 show an equilibrium between the free dication and the target adduct. Furthermore, 3a2+ has been shown to be capable of O–H bond activation using water and methanol and polymerizes THF when it is dissolved in this solvent…”
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