Targeting Pharmacological and Nanotechnology Based Therapeutics for Management of Hirsutism: A Comprehensive State-of-the-Art by Ishrat Zahoor, Sukhbir Singh, Neelam Sharma, Ikmeet Kaur Grewal, Shahid Nazir Wani

“…Hirsutism is the result of an overabundance of androgens being secreted by the ovaries or adrenal glands. This article offers a comprehensive review of numerous causes that might provoke hirsutism which includes polycystic ovarian syndrome, Cushing syndrome, idiopathic hirsutism, insulin resistance, congenital adrenal hyperplasia, ovarian or adrenal tumors, menopause, and the use of certain drugs. …”
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Folate Supplementation in Rats: Does it Cause Behavioural and Electrophysiological Changes? by Baydar Terken, Papp Andras, Nagymajtényr Laszlo, Schulz Horst, Sahin Gonul

“…Among the investigated organs, significant differences were observed in relative weight of kidneys and adrenal glands among the folic acid treatment at both the doses and the control groups (p<0.05).…”
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Microvillar channels: a unique plasma membrane compartment for concentrating lipoproteins on the surface of rat adrenal cortical cells. by E Reaven, M Spicher, S Azhar

“…In rats made acutely deficient in plasma lipoproteins (by treatment with 4-aminopyrazolo[3,4-d]pyrimidine (4-APP) for 1 day), particles within the microvillar channels are decreased in number. When adrenal glands of these rats are perfused with media lacking plasma lipoproteins, many but not all of these HDL-like particles are washed out. …”
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Body and organ weight data in 28-day toxicological studies in two mouse strains by Heike Antje Marxfeld, Karin Küttler, Martina Dammann, Sibylle Gröters, Bennard van Ravenzwaay

“…Data collected: terminal body weight, organ weights of adrenal glands, brain, epididymides, heart, kidneys, liver, ovaries, prostate, seminal vesicles (with coagulating glands), spleen, testes, thymus, uterus.b) Eight immunotoxicity studies (duration of 28 days) performed according to EPA Health Effects Test Guidelines OPPTS 870.7800 with mice from Janvier C57BL/j Rj (J). 48 control females and 16 control males 5–7 weeks old at the beginning of the studies. …”
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Multiorgan detection and characterization of protease-resistant prion protein in a case of variant CJD examined in the United States. by Silvio Notari, Francisco J Moleres, Stephen B Hunter, Ermias D Belay, Lawrence B Schonberger, Ignazio Cali, Piero Parchi, Wun-Ju Shieh, Paul Brown, Sherif Zaki, Wen-Quan Zou, Pierluigi Gambetti

“…In addition to the brain and other organs known to be prion positive in vCJD, such as the lymphoreticular system, pituitary and adrenal glands, and gastrointestinal tract, PrP(res) was also detected for the first time in the dura mater, liver, pancreas, kidney, ovary, uterus, and skin.…”
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A challenging case of Cushing’s disease complicated with multiple thrombotic phenomena following trans-sphenoidal surgery; a case report by Piyumi Sachindra Alwis Wijewickrama, Vithiya Ratnasamy, Noel P. Somasundaram, Manilka Sumanatilleke, Sathyajith Buddhika Ambawatte

“…Abstract Background Cushing’s syndrome occurs due to overproduction of cortisol from adrenal glands. Endogenous hypercortisolemia can occur secondary to adrenocorticotropic hormone (ACTH) dependent as well as independent causes. …”
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Learned helplessness and social avoidance in the Wistar-Kyoto rat by Hyungwoo eNam, Hyungwoo eNam, Sarah M Clinton, Nateka L Jackson, Ilan A Kerman

“…WKYs also showed greater social avoidance, along with enlarged adrenal glands and hearts relative to other strains. We next tested whether neonatal handling or early-life maternal separation stress influenced WKYs’ behavior. …”
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Molecular study of developmental sex disorders in children by Soheir S. AboElella, Maha A.M. Tawfik, Wafaa moustafa M. Abo El-fotoh

“…Also NR5A1 gene plays an important role in the development of gonads and the adrenal glands. Aim of the study include clinical assessment of children with disorders of sex development, molecular analyses for SRY, SOX9 and NR5A1 genes and genetic counseling for the patients and their families. …”
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Metastasis of hepatocellular carcinoma presented as a tumor of the maxillary sinus and retrobulbar tumor by Kolarević Daniela, Tomašević Zorica, Boričić Ivan, Rašić Dejan M., Anđelić-Dekić Nataša, Milovanović Zorka, Jelić Svetislav

“…Extrahepatic metastasis of HCC is an indicator of a poor prognosis and the most common sites are lungs, bones, lymph nodes, kidneys and adrenal glands. We reported a case of isolated metastasis in the right maxilla, which had been found initially, before the tumor in the liver was diagnosed. …”
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On the determination of reducing corticosteroids by Luiz Augusto de Abreu, Regina Raposo de Abreu

“…Determinations made in human urine and adrenal glands of rats and guinea pigs are comparable with results obtained by other methods.…”
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Aldosterone and aldosterone receptor antagonists in patients with chronic heart failure by Nappi J, Sieg

“…Jean M Nappi, Adam SiegClinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy, Medical University of South Carolina Campus, Charleston, SC, USAAbstract: Aldosterone is a mineralocorticoid hormone synthesized by the adrenal glands that has several regulatory functions to help the body maintain normal volume status and electrolyte balance. …”
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Pheochromocytoma-Induced Hyperglycemia Leading To Misdiagnosis Of Type 1 Diabetes Mellitus by David Bole, MD, Barbara Simon, MD, FACE

“…Magnetic resonance imaging revealed bilateral enlarged adrenal glands (left 6.5 × 6.0 × 5.7 cm; right 8.3 × 8.4 × 7.9 cm) and he was diagnosed with pheochromocytoma. …”
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Prediction of Metastatic Site Based On Somatic Gene Mutations in Primary Tumors in Prostate Cancer by Paul Gomez

“…Results After executing a computational algorithm on the data set of metastatic prostate tumors, it was found that we can predict metastatic sites with the following accuracies: bone (90.9%), retroperitoneum (87.5%), liver (83.0%), kidney (80.0%), pancreas (80.0%), adrenal glands (75.0%), lung (71.1%), and brain (72.5%). …”
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An unusual case of a posterior mediastinal myelolipoma in a patient with mediterranean anemia by Piergiorgio Muriana, Giampiero Negri

“…Myelolipoma is a benign tumor usually arising in adrenal glands. Less than 50 cases of MM have been described in the literature to date. …”
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Lipopolysaccharide Challenge Reveals Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Murine Systemic Lupus Erythematosus by Grace S. Pham, Keisa W. Mathis

“…We hypothesized that chronic inflammatory processes in SLE are in part due to HPA axis dysfunction, at the level of either the afferent vagal-paraventricular nuclei (PVN) interface, the anterior pituitary, and/or at the adrenal glands. To study this, we challenged female control and SLE mice with lipopolysaccharide (LPS) and measured c-Fos expression as an index of neuronal activation, plasma adrenocorticotrophic hormone (ACTH) as an index of anterior pituitary function, and plasma corticosterone as an index of adrenal function. …”
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A rare case of hepatocellular carcinoma with right atrial invasion by Sandeep Murgi Babukumar, Vishwanth Kumbar, Gouri Kaveriappa, Ram Shenoy Basti, H B Suresh

“…Hepatocellular carcinomas (HCCs) commonly metastasizes to the lung, bone, brain, and adrenal glands. About 70% of the patients with HCCs have hepatic and portal vein invasions but encroachment into the right atrium is very rare. …”
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Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1. by You-Ying Chau, David Brownstein, Heidi Mjoseng, Wen-Chin Lee, Natalija Buza-Vidas, Claus Nerlov, Sten Eirik Jacobsen, Paul Perry, Rachel Berry, Anna Thornburn, David Sexton, Nik Morton, Peter Hohenstein, Elisabeth Freyer, Kay Samuel, Rob van't Hof, Nicholas Hastie

“…The reduction of IGF-1 did not result from a decrease in circulating GH, and there is no apparent pathology of the pituitary and adrenal glands. These findings 1) suggest that Wt1 is a major regulator of the homeostasis of some adult tissues, through both local and systemic actions; 2) highlight the differences between foetal and adult tissue regulation; 3) point to the importance of adult mesenchyme in tissue turnover.…”
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Intermittent fasting could ameliorate cognitive function against distress by regulation of inflammatory response pathway by Marjan Shojaie, Farzane Ghanbari, Nasrin Shojaie

“…Finally, the cognitive functions of all mice were evaluated by Barnes maze, their blood samples were taken to determine the plasma level of CORT, IL-6 and TNF-α, and the removed brain and adrenal glands were weighed in the third week. A significant gain in plasma level of CORT, IL-6 and TNF-α with a considerable brain hypotrophy and adrenal hypertrophy was found in distress group, whereas IF caused a remarkable reduction of the plasma inflammatory factors, especially in IF with distress mice (P ≤ 0.05). …”
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Lung adenocarcinoma with bladder metastasis: A case report and literature review by Yuying Liu, Xinyue Dong, Tao Li, Yanke Xing, Na Liu

“…Common sites of metastasis are adrenal glands, liver, bone, and brain. Bladder metastasis is rare and should prompt a careful differential consideration of primary bladder cancer.Case descriptionHere, we report a 72-year-old female who went to the hospital for “gross hematuria for one day”. …”
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Symbiosis of cardiology and endocrinology by A. F. Verbovoy, N. I. Verbovaya, Yu. A. Dolgikh

“…The article discusses endocrine diseases in which there are manifestations from the cardiovascular system - disorders of carbohydrate metabolism, pathology of the thyroid gland, adrenal glands and acromegaly. These diseases reduce the quality of life of patients and increase the risks of cardiovascular complications. …”
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