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2241
Prognosis, Survival and Management of Pediatric Patients With Neuroblastoma: A 12-Year Experience From a Single Center Study
Published 2023-08-01“…Primary tumors were located mostly in the adrenal glands (42.34%) and abdomen (29.20%), respectively. …”
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2242
Molecular characterization and differential mRNA tissue distribution of rabbit apolipoprotein D.
Published 1990-11-01“…The highest levels of mRNA were found in spleen, adrenal glands, lungs, brain, testis, and kidneys. Moderate or low concentrations were detected in all the other organs tested including liver and small intestine. …”
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2243
Impact of Extrahepatic Metastases on Overall Survival in Patients with Advanced Liver Dominant Hepatocellular Carcinoma: A Subanalysis of the SORAMIC Trial
Published 2020-11-01“…Seventeen patients with distant organ metastases (bone, n = 11; adrenal glands, n = 5; peritoneum, n = 1) and 262 without distant metastases at study entry were analyzed in this substudy. …”
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2244
The Relative Prevalence of Testicular Adrenal Rest Tumors in Fewer than 20-Years-Old Boys with Congenital Adrenal Hyperplasia
Published 2014-09-01“…Background: Testicular adrenal rest tumor (TART) is the presence of unspecified adrenocortical cells in the testis of patients with congenital adrenal hyperplasia (CAH) and is similar to the hyperplastic adrenal glands. These tumors are usually benign; but, due to the tumor site in testicles, can lead to seminiferous tubule obstruction, gonadal dysfunction and infertility. …”
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2245
A novel method for comparison of arterial remodeling in hypertension: Quantification of arterial trees and recognition of remodeling patterns on histological sections.
Published 2019-01-01“…We performed a novel and comprehensive morphometric analysis of terminal arteries in the brain, heart, lung, liver, kidney, spleen, stomach, intestine, skin, skeletal muscle, and adrenal glands of control and Goldblatt hypertensive rats on routinely processed tissue sections. …”
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2246
Effect of neonatal dexamethasone treatment on cognitive abilities of adult male mice and gene expression in the hypothalamus
Published 2019-07-01“…In adult male mice with neonatal dexamethasone treatment, an increase in the relative weight of the adrenal glands and a decrease in body weight were observed, while the basal level of corticosterone remained unchanged. …”
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2247
Brain-Derived Steroids, Behavior and Endocrine Conflicts Across Life History Stages in Birds: A Perspective
Published 2018-06-01“…Biological steroids were traditionally thought to be synthesized exclusively by the adrenal glands and gonads. Recent decades have seen the discovery of neurosteroid production that acts locally within the central nervous system to affect physiology and behavior. …”
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2248
Non-classical congenital adrenal hyperplasia. Clinical case
Published 2023-03-01“…Congenital adrenal hyperplasia (CAH) is an autosomal recessive disease emerging from mutations of genes for enzymes that lead to the biochemical shifts in the production of glucocorticoids, mineralocorticoids, or sex steroids from cholesterol by the adrenal glands. Universal newborn screening for CAH is recommended for early diagnosis and initiation of therapy. …”
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2249
Glycogen storage disease presenting as Cushing syndrome
Published 2019-05-01“…This is in contrast to typical CS, which is due to excessive adrenocorticotropic hormone (ACTH) or cortisol secretion from neoplastic pituitary or adrenal glands, ectopic secretion of ACTH or corticotropin‐releasing hormone (CRH), or exogenous administration of corticosteroid or ACTH. …”
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2250
Adrenal insufficiency in immunochemotherapy for small-cell lung cancer with ectopic ACTH syndrome
Published 2021-10-01“…Chest and abdominal CT revealed a right lower lobe tumour with multiple metastases on the hilar lymph nodes, liver, lumbar spine, and bilateral enlarged adrenal glands. The patient was diagnosed with stage 4B SCLC with EAS. …”
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2251
Different Clinical Manifestations Related to Subvirilization in Three XY Patients With the Same Pathogenic Variant of Steroidogenic Factor 1
Published 2021-03-01“…Objective: During the prenatal period, steroidogenic factor 1 is required for the development of the adrenal glands and for gonadal determination and differentiation, and after birth, it regulates gonadal progenitor cell formation and their survival. …”
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2252
A randomized, placebo-controlled, double-blind study to confirm the reversal of hepatorenal syndrome type 1 with terlipressin: the REVERSE trial design
Published 2012-07-01“…Type 1 HRS is a rapidly progressive acute kidney injury that develops shortly after a precipitating event, followed by a deterioration of function of other organs (eg, heart, brain, liver, adrenal glands). Presently, no approved drug therapies exist for HRS type 1 in the USA, Canada, or Australia. …”
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2253
Feline coronavirus-associated myocarditis in a domestic longhair cat
Published 2019-10-01“…Necropsy revealed multifocal pyogranulomatous lesions involving multiple organs (adrenal glands, kidneys, lungs, brain, myocardium, lymph nodes, liver), compatible with the diagnosis of FIP. …”
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2254
Devastating salt‐wasting crisis in a four‐month‐old male child with congenital adrenal hyperplasia, highlighting the essence of neonatal screening
Published 2022-07-01“…Abstract Congenital adrenal hyperplasia (CAH) is a rare condition usually referred to as a group of genetic disorders resulting due to a deficiency of steroid enzymes required by adrenal glands to produce cortisol and mineralocorticoid hormones. …”
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2255
Postmenopausal hyperandrogenism due to an ovarian sex cord-stromal tumour causing elevated dehydroepiandrosterone sulphate: a case report
Published 2022-07-01“…Contrast-enhanced computed tomography of the abdomen and pelvis showed a heterogeneously enhancing complex mass measuring 11 × 8 cm in the left adnexal region. Adrenal glands were normal. She underwent total abdominal hysterectomy, bilateral salphingo-oophorectomy, and omentectomy. …”
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2256
Neuroimmunomodulation of adrenoblockers during liver cirrhosis: modulation of hepatic stellate cell activity
Published 2023-12-01“…The sympathetic nervous system regulates hepatic fibrosis through sympathetic fibres and adrenaline from the adrenal glands through the blood. When there is liver damage, the sympathetic nervous system is activated locally and systemically through proinflammatory cytokines that induce the production of epinephrine and norepinephrine. …”
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2257
Use of oral contraceptives in the management of acne
Published 2011-11-01“…Androgens originate from the gonads and adrenal glands, but can also be locally produced within the sebaceous gland from dehydroepiandrosterone sulfate. …”
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2258
Polycystic ovary syndrome (PCOS) - risk factor, diagnostic and current treatment
Published 2020-09-01“…</p><p><strong>Description of the state of knowledge:</strong><strong></strong></p><p> PCOS is characterized by an excessive secretion of androgens from the ovaries and / or adrenal glands. Intrinsic ovarian factors, such as altered steroidogenesis, and factors external to the ovary, such as hyperinsulinemia, contribute to the ovarian overproduction of androgens. …”
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2259
Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression.
Published 2018-01-01“…These genes were not differentially expressed in ASP mice with CGP antagonism. In the adrenal glands of ASP-exposed mice, GABA and Glutamate receptor subunit genes were amongst those most highly upregulated. …”
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2260
The PI3K/AKT/mTOR signaling pathway is overactivated in primary aldosteronism.
Published 2013-01-01“…To answer this question, we investigated the activity of the PI3K/AKT/mTOR signaling pathway in normal adrenal glands (NAGs), primary aldosteronism (PA) patients and NCI-H295R cells. …”
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