Effect of Endotoxemia in Suckling Rats on Pancreatic Integrity and Exocrine Function in Adults: A Review Report by Jolanta Jaworek, Barbara Tudek, Paweł Kowalczyk, Michalina Kot, Joanna Szklarczyk, Anna Leja-Szpak, Piotr Pierzchalski, Joanna Bonior, Artur Dembiński, Piotr Ceranowicz, Zygmunt Warzecha, Katarzyna Nawrot-Porąbka, Krzysztof Gil

“…The effects of LPS applied to the suckling rats on the pancreas of adult animals have not been previously explored. We present the impact of neonatal endotoxemia on the pancreatic exocrine function and on the acute pancreatitis which has been investigated in the adult animals. …”
Get full text

Effects of Viewing Cute Pictures on Quiet Eye Duration and Fine Motor Task Performance by Naoki Yoshikawa, Hiroshi Nittono, Hiroaki Masaki

“…We randomly assigned participants to either the baby-animal pictures group or the adult-animal pictures group, based on pictures viewed prior to the task. …”
Get full text

Effect of gold and silver nanoparticles on the morpho-functional state of the epididymis and prostate gland in rats by V. Y. Kalynovskyi, A. S. Pustovalov, G. Y. Grodzyuk, N. S. Andriushyna, M. E. Dzerzhynsky

“…At the same time, nanogold caused more morphometric changes in adult animals. Similar results were obtained from the nanosilver groups. …”
Get full text

PHGDH supports liver ceramide synthesis and sustains lipid homeostasis by Yun Pyo Kang, Aimee Falzone, Min Liu, Paloma González-Sánchez, Bo-Hyun Choi, Jonathan L. Coloff, James J. Saller, Florian A. Karreth, Gina M. DeNicola

“…With this model, PHGDH depletion can be globally induced in adult animals, while sparing the brain due to poor doxycycline delivery. …”
Get full text

Inducible and reversible inhibition of miRNA-mediated gene repression in vivo by Gaspare La Rocca, Bryan King, Bing Shui, Xiaoyi Li, Minsi Zhang, Kemal M Akat, Paul Ogrodowski, Chiara Mastroleo, Kevin Chen, Vincenzo Cavalieri, Yilun Ma, Viviana Anelli, Doron Betel, Joana Vidigal, Thomas Tuschl, Gunter Meister, Craig B Thompson, Tullia Lindsten, Kevin Haigis, Andrea Ventura

“…We demonstrate the usefulness of this strategy by investigating the consequences of acute inhibition of miRNA function in adult animals. We find that different tissues and organs respond differently to global loss of miRNA function. …”
Get full text

Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia. by Celine Saint-Laurent, Stephanie Garcia, Vincent Sarrazy, Karine Dumas, Florence Authier, Sophie Sore, Albert Tran, Philippe Gual, Isabelle Gennero, Jean-Pierre Salles, Elvire Gouze

“…Treating Fgfr3ach/+ mice with soluble FGFR3 during the growth period, prevented the development of these metabolic deregulations in adult animals and restored lean-over-fat tissues ratio as well as glucose metabolism in adult animals.This study demonstrate that achondroplasia patients develop an atypical obesity with preferential abdominal obesity not associated with classical complications. …”
Get full text

Long-Term Hypercaloric Diet Consumption Exacerbates Age-Induced Dysmetabolism and Carotid Body Dysfunction: Beneficial Effects of CSN Denervation by Bernardete F. Melo, Joana F. Sacramento, Adriana M. Capucho, Dinis Sampaio-Pires, Cláudia S. Prego, Silvia V. Conde

“…Adult animals showed decreased type I cells and IR and GLP-1R staining without altering the number of type II cells and HIF-1α. …”
Get full text

Are there differences in the growth adaptation processes of growing and mature organism models of short bowel syndrome? by Ana Cristina Aoun Tannuri, ĺtalo Geraldo Rotondo, Guilherme Garcia Barros, Victor Van Vaisberg, Cícero Mendes-Neto, Vitor Ribeiro Paes, Maria Cecilia Mendonça Coelho, Josiane Gonçalves, Suellen Serafini, Uenis Tannuri

“…OBJECTIVES: The purpose of this study was to present an experimental model of short bowel syndrome (SBS) in weaning rats and to compare the adaptative mechanisms of the remaining bowel in weaning rats and adult animals by means of morphometric, histologic and molecular methods. …”
Get full text

Distribution of the stx1 and stx2 genes in Escherichia coli isolated from milk cattle according to season, age, and production scale in southwestern region of Goiás, Brazil by M.R.A. Ferreira, A.E. Stella, E.G. Freitas-Filho, T.S. Silva, K.A. Nascimento, J.F.N. Pinto, M. Dias, C.N. Moreira

“…The most predominant phylogenetic groups in adult animals were B1, A, and D, while groups A and B1 prevailed in calves. …”
Get full text

A COMPARATIVE EVALUATION OF THE LEAD II ELECTROCARDIOGRAM IN YOUNG AND ADULT CROSSBRED COWS OF ODISHA by Swagat Mohapatra, Sunil Kumar Mohapatra, Subhashree Sarangi, Tushar Jyotiranjan, Pravas Ranjan Sahoo, Akshya Kumar Kundu

“…The P wave had a positive configuration in both young and adult animals. As far as the amplitude of P-wave was concerned, the young animals recorded significantly higher values than adults. …”
Get full text

<b>Testis evaluation of adult Wistar rats after neonatal treatment with fluoxetine</b> - doi: 10.4025/actascibiolsci.v35i1.10946 by Valdemiro Amaro da Silva Junior, Waldo Oliveira Monteiro Filho, Catarina Ferreira Pinto, Sandra Maria de Torres, Bruno Mendes Tenorio

“…However, testicular parameters, such as daily sperm production (DSP), spermatogenesis efficiency (DSP/g/testis) and cell population in stage VII of adult animals, were not influenced by fluoxetine chlorohydrate usage during neonatal period. …”
Get full text

The CRISPR revolution and its impact on cancer research by Ram Kannan, Andrea Ventura

“…By providing simple, flexible, and cost-effective ways to edit and manipulate the genome of somatic cells of adult animals, these new methods present the opportunity to model cancer progression in vivowith an unprecedented degree of sophistication. …”
Get full text

Culture of adult mouse neurons by Lars Eide, Cynthia T. McMurray

“…Successful culturing of neurons from adult animals, however, has been historically difficult, if not impossible. …”
Get full text

Gene Expression Changes after Parental Exposure to Metals in the Sea Urchin Affect Timing of Genetic Programme of Embryo Development by Tiziana Masullo, Girolama Biondo, Marilena Di Natale, Marcello Tagliavia, Carmelo Daniele Bennici, Marianna Musco, Maria Antonietta Ragusa, Salvatore Costa, Angela Cuttitta, Aldo Nicosia

“…To assess if the exposure of adult animals could result in effects on the offspring, the Mediterranean sea urchin and its well-characterized gene regulatory networks (GRNs) was chosen as a model. …”
Get full text

Morphological, metabolic and functional repercussions after orchiectomy in rats by Denny Fabrício Magalhães Veloso, Luiz Ronaldo Alberti, Juliano Alves Figueiredo, Fernando Henrique Oliveira Carmo Rodrigues, Andy Petroianu

“…Cconclusions: Castration reduces blood levels of triglycerides and VLDL cholesterol in young rats. In adult animals, it increases arterial pressure and is related to smaller weight gain.…”
Get full text

Projection neurons are necessary for the maintenance of the mouse olfactory circuit by Luis Sánchez-Guardado, Peyman Razavi, Bo Wang, Antuca Callejas-Marín, Carlos Lois

“…Moreover, ablating the M/Ts in adult animals also resulted in similar structural changes in the projections of remaining M/Ts and axons from OSNs. …”
Get full text

Auditory training during development mitigates a hearing loss-induced perceptual deficit. by Ramanjot eKang, Emma eSarro, Dan eSanes, Dan eSanes

“…In the auditory system, early induction of conductive hearing loss (CHL) leads to deficits in central auditory coding properties in adult animals, and this is accompanied by diminished perceptual thresholds. …”
Get full text

Eficácia de anti-helmínticos no controle de parasitas gastrintestinais de ovinos no Alto Sertão da Paraíba, Brasil by José Gabriel Gonçalves Lins, Amélia Lizziane Leite Duarte, Talles Luann Abrantes Ferreira, Amaíra Casimiro do Nascimento, Paloma Nascimento Pedrosa, Wellitania Inácia da Silva

“…In P1 each group was formed by three young and three adult animals, while in P2 each group was formed by two young and three adult animals. …”
Get full text

C. elegans Notch Signaling Regulates Adult Chemosensory Response and Larval Molting Quiescence by Singh, Komudi, Chao, Michael Y., Somers, Gerard A., Komatsu, Hidetoshi, Corkins, Mark E., Larkins-Ford, Jonah, Tucey, Tim, Dionne, Heather M., Walsh, Melissa B., Beaumont, Emma K., Hart, Douglas, Lockery, Shawn R., Hart, Anne C.

“…In adult animals, overexpression of osm-11 and consequent Notch receptor activation induces anachronistic sleep-like quiescence. …”
Get full text
Get full text

Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents by Rajneesh Chaudhary, Kislay Roy, Rupinder Kaur Kanwar, Ken Walder, Jagat Rakesh Kanwar

“…MRI scans of contrast agent injected animal revealed significant arterial narrowing and a significantly higher T2 (p < 0.05, 1.71-fold) contrast in adult animals when compared to juvenile and control animals. …”
Get full text