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201
Engineering biosynthesis of the anticancer alkaloid noscapine in yeast
Published 2016-07-01Get full text
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202
Pyrrolizidine alkaloids of senecio sp from Peru
Published 2011-01-01Subjects: Get full text
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203
Research Progress on Neuroprotective Effects of Isoquinoline Alkaloids
Published 2023-06-01Subjects: “…isoquinoline alkaloids…”
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204
A Many-Faced Alkaloid: Polymorphism of (–)-Monophyllidin
Published 2020-01-01Subjects: Get full text
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205
Pyrrolizidine alkaloids: An update on their metabolism and hepatotoxicity mechanism
Published 2019-12-01“…Pyrrolizidine alkaloids (PAs) are among the most hepatotoxic natural compounds that are widely distributed throughout the world. …”
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206
Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production
Published 2019-02-01Subjects: “…tropane alkaloids…”
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207
Biological Activities of Alkaloids: From Toxicology to Pharmacology
Published 2020-03-01Get full text
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208
Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae
Published 2015-12-01“…ABSTRACT This study assessed the occurrence and distribution of tropane alkaloids and calystegines in genera of the family Solanaceae to identify patterns of distribution and make evolutionary inferences. …”
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209
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Application of hydroformylation for the stereoselective synthesis of piperidine alkaloids
Published 2014“…The second and third chapters describe the synthesis of pseudoconhydrine and azimic acid using a common methodology that incorporates hydroformylation, for a simple yet efficient stereoselective synthesis of these types of piperidine alkaloids. The fourth chapter explores the advantages of application of hydroformylation in flow chemistry. …”
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211
Synthesis of polyhydroxylated alkaloids via allene cyclisation
Published 2014“…Polyhydroxylated alkaloids, a class of natural products prevalent in plants, have attracted the interest of many due to their rich biological activities and complex chemical structures. …”
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212
Enantioselective desymmetrisation towards the synthesis of daphniphyllum alkaloids
Published 2019“…<p>Chapter One introduces the Daphniphyllum alkaloids and the Calyciphylline A- type alkaloid sub-family, including proposed biosyntheses and recently reported total syntheses. …”
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213
The Aza-Bohlmann cyclisation and the synthesis of Pandanus alkaloids
Published 2011“…</p><p>The first total synthesis of the spiroaminoacetal alkaloid pandamarilactone-1 is discussed, via an aza-Bohlmann cyclisation, in 13 steps and 3% overall yield from 4-pentyn-1-ol.…”
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214
Polyhydroxylated alkaloids -- natural occurrence and therapeutic applications.
Published 2001“…Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. …”
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215
Inhibition of mammalian digestive disaccharidases by polyhydroxy alkaloids.
Published 1986“…Several polyhydroxy alkaloids, including the eight presently known to occur in plants, have been compared as inhibitors of mouse gut digestive disaccharidases. …”
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216
Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis
Published 2016“…This review covers the isolation and structure of new pyrrolizidines; pyrrolizidine biosynthesis; biological activity, including the occurrence of pyrrolizidines as toxic components or contaminants in foods and beverages; and formal and total syntheses of naturally-occurring pyrrolizidine alkaloids and closely related non-natural analogues.…”
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217
Asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C
Published 2013“…The first asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C is described. This synthesis employs the conjugate addition of lithium dibenzylamide to an N-α-phenylacryloyl SuperQuat derivative followed by diastereoselective protonation of the intermediate enolate using 2-pyridone as the key step to introduce the stereochemistry. (-)-(S)-Nakinadine C was isolated in 13% yield over 9 steps from commercially available atropic acid, 98:2 dr [(Z):(E) ratio] and >99% ee. © 2013 Elsevier Ltd. …”
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218
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Development of an alkaloid–pyrone annulation: synthesis of pleiomaltinine
Published 2012“…The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine.…”
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220
Alkaloids from Fissistigma latifolium (Dunal) Merr
Published 2010“…A phytochemical study of the bark of Fissistigma latifolium (Annonaceae) yielded a new aporphine alkaloid, (-)-N-methylguattescidine (1), and eight known alkaloids: liriodenine (2), oxoxylopine (3), (-)-asimilobine (4), dimethyltryptamine (5), (-)-remerine (6), (-)-anonaine (7), columbamine (8) and lysicamine (9). …”
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