Showing 201 - 220 results of 11,268 for search '"alkaloid"', query time: 0.18s Refine Results
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    Pyrrolizidine alkaloids: An update on their metabolism and hepatotoxicity mechanism by Jie Xu, Weiqian Wang, Xiao Yang, Aizhen Xiong, Li Yang, Zhengtao Wang

    Published 2019-12-01
    “…Pyrrolizidine alkaloids (PAs) are among the most hepatotoxic natural compounds that are widely distributed throughout the world. …”
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    Article
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    Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae by Aline G.S. Pigatto, Carolina C. Blanco, Lilian A. Mentz, Geraldo L.G. Soares

    Published 2015-12-01
    “…ABSTRACT This study assessed the occurrence and distribution of tropane alkaloids and calystegines in genera of the family Solanaceae to identify patterns of distribution and make evolutionary inferences. …”
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    Article
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    Application of hydroformylation for the stereoselective synthesis of piperidine alkaloids by Sivarajan Kasinathan

    Published 2014
    “…The second and third chapters describe the synthesis of pseudoconhydrine and azimic acid using a common methodology that incorporates hydroformylation, for a simple yet efficient stereoselective synthesis of these types of piperidine alkaloids. The fourth chapter explores the advantages of application of hydroformylation in flow chemistry. …”
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    Thesis
  11. 211

    Synthesis of polyhydroxylated alkaloids via allene cyclisation by Ng, Pearly Shuyi

    Published 2014
    “…Polyhydroxylated alkaloids, a class of natural products prevalent in plants, have attracted the interest of many due to their rich biological activities and complex chemical structures. …”
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    Thesis
  12. 212

    Enantioselective desymmetrisation towards the synthesis of daphniphyllum alkaloids by Ellis, SR

    Published 2019
    “…<p>Chapter One introduces the Daphniphyllum alkaloids and the Calyciphylline A- type alkaloid sub-family, including proposed biosyntheses and recently reported total syntheses. …”
    Thesis
  13. 213

    The Aza-Bohlmann cyclisation and the synthesis of Pandanus alkaloids by Macnaughton, S, Sarah Macnaughton

    Published 2011
    “…</p><p>The first total synthesis of the spiroaminoacetal alkaloid pandamarilactone-1 is discussed, via an aza-Bohlmann cyclisation, in 13 steps and 3% overall yield from 4-pentyn-1-ol.…”
    Thesis
  14. 214

    Polyhydroxylated alkaloids -- natural occurrence and therapeutic applications. by Watson, A, Fleet, G, Asano, N, Molyneux, R, Nash, R

    Published 2001
    “…Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. …”
    Journal article
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    Inhibition of mammalian digestive disaccharidases by polyhydroxy alkaloids. by Scofield, A, Fellows, L, Nash, R, Fleet, G

    Published 1986
    “…Several polyhydroxy alkaloids, including the eight presently known to occur in plants, have been compared as inhibitors of mouse gut digestive disaccharidases. …”
    Journal article
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    Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis by Robertson, J, Stevens, K

    Published 2016
    “…This review covers the isolation and structure of new pyrrolizidines; pyrrolizidine biosynthesis; biological activity, including the occurrence of pyrrolizidines as toxic components or contaminants in foods and beverages; and formal and total syntheses of naturally-occurring pyrrolizidine alkaloids and closely related non-natural analogues.…”
    Journal article
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    Asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C by Davies, S, Roberts, P, Shah, R, Thomson, J

    Published 2013
    “…The first asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C is described. This synthesis employs the conjugate addition of lithium dibenzylamide to an N-α-phenylacryloyl SuperQuat derivative followed by diastereoselective protonation of the intermediate enolate using 2-pyridone as the key step to introduce the stereochemistry. (-)-(S)-Nakinadine C was isolated in 13% yield over 9 steps from commercially available atropic acid, 98:2 dr [(Z):(E) ratio] and &gt;99% ee. © 2013 Elsevier Ltd. …”
    Journal article
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    Development of an alkaloid–pyrone annulation: synthesis of pleiomaltinine by Kam, T.S., Ziegler, R.E., Tan, S.J., Porco Jr., J.A.

    Published 2012
    “…The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine.…”
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    Article
  20. 220

    Alkaloids from Fissistigma latifolium (Dunal) Merr by Alias, A., Hazni, H., Jaafar, F.M., Awang, K., Ismail, N.H.

    Published 2010
    “…A phytochemical study of the bark of Fissistigma latifolium (Annonaceae) yielded a new aporphine alkaloid, (-)-N-methylguattescidine (1), and eight known alkaloids: liriodenine (2), oxoxylopine (3), (-)-asimilobine (4), dimethyltryptamine (5), (-)-remerine (6), (-)-anonaine (7), columbamine (8) and lysicamine (9). …”
    Article