Showing 221 - 240 results of 7,210 for search '"alkaloid"', query time: 0.09s Refine Results
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    The Impact of Storage Temperature and Time on Ergot Alkaloid Concentrations by Jensen E. Cherewyk, Taylor J. Grusie-Ogilvie, Sarah E. Parker, Barry R. Blakley, Ahmad N. Al-Dissi

    Published 2023-08-01
    “…Ergot sclerotia produce toxic secondary metabolites, ergot alkaloids, that infect cereal crops and grasses. Ergot alkaloids have two isomeric configurations: the C-8-<i>R</i>-isomer (<i>R</i>-epimer), and the C-8-<i>S</i>-isomer (<i>S</i>-epimer). …”
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    Opportunities in metabolic engineering to facilitate scalable alkaloid production by Leonard, Effendi, Runguphan, Weerawat, O'Connor, Sarah Ellen, Prather, Kristala L. Jones

    Published 2012
    “…In this Perspective, we discuss the opportunities and challenges of implementing metabolic engineering in various platforms for the synthesis of natural and unnatural plant alkaloids.…”
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  16. 236

    Dimerization of functional pyrroloindolizines for the synthesis of complex myrmicarin alkaloids by Ondrus, Alison E., Kaniskan, Husnu Umit, Movassaghi, Mohammad

    Published 2012
    “…The union of functionalized pyrroloindolizines for the synthesis of heterodimeric products relevant to myrmicarin alkaloids is described. Design and synthesis of tricyclic substrates and new methods for their union enable the investigation of late-stage cyclopentannulation strategies. …”
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  17. 237

    Synthesis and Anticancer Activity of All Known (−)-Agelastatin Alkaloids by Han, Sunkyu, Siegel, Dustin S., Morrison, Karen C., Hergenrother, Paul J., Movassaghi, Mohammad

    Published 2015
    “…Our concise synthesis of these alkaloids exploits the intrinsic chemistry of plausible biosynthetic precursors and capitalizes on a late-stage synthesis of the C-ring. …”
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    Aza-Tryptamine Substrates in Monoterpene Indole Alkaloid Biosynthesis by Lee, Hyang-Yeol, Yerkes, Nancy Mary, O'Connor, Sarah Ellen, Yerkes, Nancy Mary

    Published 2015
    “…Here we have altered tryptamine, which serves as the starting substrate for a variety of alkaloid biosynthetic pathways, by replacing the indole with one of four aza-indole isomers. …”
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    Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids by Kim, Justin, Movassaghi, Mohammad

    Published 2015
    “…It is with this ethos that our group has taken an interest in and pursued the synthesis of a complex family of natural products termed the dimeric epipolythiodiketopiperazine (ETP) alkaloids. We present here an Account of the highly complex target molecules to which we pegged our ambitions, our systematic and relentless efforts toward those goals, the chemistry we developed in their pursuit, and the insight we have gained for their translational potential as potent anticancer molecules.…”
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