Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products by Solida Long, Diana I. S. P. Resende, Anake Kijjoa, Artur M. S. Silva, André Pina, Tamara Fernández-Marcelo, M. Helena Vasconcelos, Emília Sousa, Madalena M. M. Pinto

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Development and application of new strategies for synthesis of complex diketopiperazine alkaloids by Nelson, Brandon M. (Brandon Michael)

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Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture by O'Connor, Sarah Ellen, Maresh, Justin J., Runguphan, Weerawat

“…To exploit this chemically silent background, we introduced an unnatural tryptamine analog to the production media and demonstrated that the silenced plant culture could produce a variety of novel products derived from this unnatural starting substrate. The novel alkaloids were not contaminated by the presence of the natural alkaloids normally present in C. roseus. …”
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Total synthesis of Class II and Class III Galbulimima Alkaloids by Tjandra, Meiliana

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Reprogramming alkaloid biosynthesis in Catharanthus roseus : synthetic biology in plants by Runguphan, Weerawat

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Radical-mediated Dimerization and Oxidation Reactions for the Synthesis of Complex Alkaloids by Lathrop, Stephen, Kim, Justin, Movassaghi, Mohammad

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Antinociceptive effects of alkaloids rich fraction of aidia densiflora in mice by Soib, Husnul Hanani, Wan Sulaiman, Wan Mohd. Azizi, Darnis, Deny Susanti, Tg Zakaria, Tg Muhammad Faris Syafiq, Edueng, Khadijah, Bakhtiar, M. Taher

“…Four groups of mice were separated and treated with alkaloids extract from AD at increasing doses of 100, 200, 500, 1000 mg/kg. …”
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Isolation of the pyrrolizidine alkaloid 1-epialexine from Castanospermum australe by Jones, L, Hollinshead, J, Fleet, G, Thompson, A, Watkin, D, Gal, Z, Jenkinson, S, Kato, A, Nash, R

“…The Australian leguminous tree Castanospermum australe contains the anti-viral glucose analogue indolizidine alkaloid castanospermine. As the result of a search for new bioactive carbohydrate-like compounds we now report the isolation of the novel polyhydroxylated pyrrolizidine alkaloid, 1-epialexine, from the leaves and stems of C. australe. 1-Epialexine is a weak inhibitor of β-mannosidase from Cellullomonas fimi. © 2010 Phytochemical Society of Europe.…”

A practical and scaleable total synthesis of the jaborandi alkaloid (+)-pilocarpine by Davies, S, Roberts, P, Stephenson, P, Storr, H, Thomson, J

Total synthesis of the pyrrolizidine alkaloid natural product NP25302 by Stevens, K, Robertson, J

Investigation into the absolute stereochemistry of the marine sponge alkaloid pyrinodemin A by Romeril, S, Lee, V, Baldwin, J, Claridge, T, Odell, B

“…The absolute configuration of the marine sponge alkaloid pyrinodemin A is established by organic synthesis. © 2003 Elsevier Ltd. …”

ORGN 549-Cascade approaches to the total synthesis of the lepadin alkaloids by Thompson, S, Smith, M

Bifunctional organo/metal cooperative catalysis with cinchona alkaloid scaffolds by Stegbauer, L, Sladojevich, F, Dixon, D

“…This review discusses recent developments (the last 10 years) in the field of cooperative catalysis using cinchona alkaloid derivatives in combination with metal ions, highlighting the potential of this new research area and the many challenges that still remain for the future. …”

Steviamine, a new indolizidine alkaloid from Stevia rebaudiana by Michalik, A, Hollinshead, J, Jones, L, Fleet, G, Yu, C, Hu, X, van Well, R, Horne, G, Wilson, F, Kato, A, Jenkinson, S, Nash, R

“…This is the first report of an indolizidine iminosugar alkaloid from the Asteraceae and Hyacinthaceae. Steviamine may occur in some Stevia products and influence taste. © 2010 Phytochemical Society of Europe.…”

Total synthesis of cytotoxic sponge alkaloids hachijodines F and G by Goundry, W, Lee, V, Baldwin, J

“…The total synthesis of two cytotoxic sponge alkaloids hachijodines F (1) and G (2) via a common intermediate 3 is described. © 2002 Elsevier Science Ltd. …”

Asymmetric syntheses of the homalium alkaloids (-)-(S,S)-homaline and (-)-(R,R)-hopromine. by Davies, S, Lee, J, Roberts, P, Stonehouse, J, Thomson, J

“…The highly diastereoselective conjugate additions of the novel lithium amide reagents lithium (R)-N-(3-chloropropyl)-N-(α-methylbenzyl)amide and lithium (R)-N-(3-chloropropyl)-N-(α-methyl-p-methoxybenzyl)amide to α,β-unsaturated esters were used as the key steps in syntheses of the homalium alkaloids (-)-(S,S)-homaline and (-)-(R,R)-hopromine. …”

Strategies towards the synthesis of calyciphylline A-type Daphniphyllum alkaloids. by Kang, B, Jakubec, P, Dixon, D

“…The Daphniphyllum alkaloids are a diverse family of natural products rich in number and structural diversity that have been known for many decades. …”

GLYCOSIDASE INHIBITION BY PLANT ALKALOIDS WHICH ARE STRUCTURAL ANALOGS OF MONOSACCHARIDES by Evans, S, Fellows, L, Shing, T, Fleet, G

“…]The inhibitory activities of three plant alkaloids, deoxynojirimycin, 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine and 1,5 dideoxy-1,5-imino-D-mannitol towards glycosidases from several sources have been compared. …”

Total synthesis of cytotoxic sponge alkaloids Motuporamines A and B by Baldwin, J, Vollmer, H, Lee, V

“…The synthesis of two sponge alkaloids, Motuporamines A and B is reported. The key step involved a reductive amination using sodium triacetoxyborohydride.…”

Total synthesis of cytotoxic sponge alkaloids hachijodines F and G by Goundry, W, Baldwin, J, Lee, V

“…The total synthesis of two cytotoxic sponge alkaloids hachijodines F and G has been achieved. The synthesis of both compounds utilises a common intermediate alkyne. …”