A New Cytotoxic Steroidal Glycoalkaloid from the Methanol Extract of Blumea lacera Leaves by Raushanara Akter, Shaikh J. Uddin, Joe Tiralongo, I. Darren Grice, Evelin Tiralongo

“…Cytotoxic activity of 1 and seven SGA analogues and steroidal alkaloids (SAs), (β-solamarine, α-solanine, β-solamargine, α-solasonine, khasianine, solasodine, tomatidine HCl) were evaluated for their cytotoxicity against two healthy (NIH3T3 and VERO) and four human cancer (AGS, HT-29, MCF-7 and MDA-MB-231) cell lines using the MTT assay. …”
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Analysis of antidiabetic, antiulcer and analgesic potential of traditional ethnomedicinal plant Emex spinosa (L.) Campd. from Azad Jammu and Kashmir by Muhammad Ajaib, Saiqa Ishtiaq, Muhammad Ishtiaq, Mehwish Maqbool, Khizar Hayat Bhatti, Afsheen Khan, Afeera Afreen, Tanveer Hussain, Tauqeer Sardar, Alia Gul, Muhammad Azeem

“…The quantitative phytochemical analysis of the extract revealed flavonoids were highest in leaf extract (15.63±0.93 mg/mL) and with (11.5±0.57 mg/mL) in stem. Alkaloids and tanins were also present in the samples in various conc. while saponins were absent. …”
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Restoration of Hepatic and Intestinal Integrity by <i>Phyllanthus amarus</i> Is Dependent on Bax/Caspase 3 Modulation in Intestinal Ischemia-/Reperfusion-Induced Injury by Ayobami Oladele Afolabi, Tunmise Maryanne Akhigbe, Adeyemi Fatai Odetayo, Davinson Chuka Anyogu, Moses Agbomhere Hamed, Roland Eghoghosoa Akhigbe

“…The beneficial effects of <i>Phyllanthus</i> <i>amarus</i> may be ascribed to its constituent bioactive molecules, especially tannins, anthocyanin, alkaloids, and phenolics.…”
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Evaluation of the effect of jasmonic acid elicitation on composition of pigments and biological activities in green callus of neem (Azadirachta indica) by Nurul Syazwani Ahmad Fauzi, Muhamad Hafiz Abd Rahim, Nazia Abdul Majid, Rashidi Othman, Jamilah Syafawati Yaacob, Jamilah Syafawati Yaacob

“…Phytochemical screening revealed the presence of alkaloids, flavonoids, phenols, tannins, and terpenoids in all 4- and 8-week-old samples elicited with 2, 4 and 6 mg/L JA. …”
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Effectiveness of Drug Repurposing and Natural Products Against SARS-CoV-2: A Comprehensive Review by Velásquez PA, Hernandez JC, Galeano E, Hincapié-García J, Rugeles MT, Zapata-Builes W

“…Additionally, therapeutic options have been sought in natural products (terpenoids, alkaloids, saponins and phenolics) with promising in vitro and in silico results for use in COVID-19 disease. …”
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Analysis of antidiabetic, antiulcer and analgesic potential of traditional ethnomedicinal plant Emex spinosa (L.) Campd. from Azad Jammu and Kashmir. by Muhammad Ajaib, Saiqa Ishtiaq, Muhammad Ishtiaq, Mehwish Maqbool, Khizar Hayat Bhatti, Afsheen Khan, Afeera Afreen, Tanveer Hussain, Tauqeer Sardar, Alia Gul, Muhammad Azeem

“…The quantitative phytochemical analysis of the extract revealed flavonoids were highest in leaf extract (15.63±0.93 mg/mL) and with (11.5±0.57 mg/mL) in stem. Alkaloids and tanins were also present in the samples in various conc. while saponins were absent. …”
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Metabolomic Reconfiguration in Primed Barley (<i>Hordeum vulgare</i>) Plants in Response to <i>Pyrenophora teres</i> f. <i>teres</i> Infection by Claude Y. Hamany Djande, Fidele Tugizimana, Paul A. Steenkamp, Lizelle A. Piater, Ian A. Dubery

“…For targeted studies, selected metabolites from the amino acids, phenolic acids, and alkaloids classes were quantified using multiple reaction monitoring (MRM) mass spectrometry. 3,5-DCAA was effective as a priming agent in delaying the onset and intensity of symptoms but could not prevent the progression of the disease. …”
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Arctium lappa root extract based emulgels attenuate inducible cytokines and prostaglandins formation: Potential in the management of chronic inflammatory disorders by Adeola Tawakalitu Kola-Mustapha, Muhammed Olawale Abdulrahman, Ismail O. Ishola

“…Results: The preliminary qualitative phytochemical analysis of Arctium lappa root extract gave tannins, saponins, phenolics, steroids, glycosides, flavonoids, anthocyanin, terpenoids, and alkaloids as its contents. The extract's inhibitory activities on PGE-2, COX-2 and TNF-α were dose dependent. …”
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Ligusticum chuanxiong Hort as a medicinal and edible plant foods: Antioxidant, anti-aging and neuroprotective properties in Caenorhabditis elegans by Yihan Qin, Fangfang Chen, Zizhong Tang, Hongjiao Ren, Qing Wang, Nayu Shen, Wenjie Lin, Yirong Xiao, Ming Yuan, Hui Chen, Tongliang Bu, Qingfeng Li, Lin Huang

“…In this study, we detected 74 and 78 compounds from CXR and CXL, respectively, including phthalides, alkaloids, organic acids, terpenes, polyphenols and others. …”
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Phytochemical study of Malaysian Uncaria cord at a var. Ferruginea (Bl.) RIDSD and its anti-hyperglycemic potential / Nur Hakimah Abdullah by Abdullah, Nur Hakimah

“…This is also the first report on the non-alkaloidal constituents of the plant. Their in vitro anti-hyperglycemic potential have provided some scientific evidence on the traditional use of the plant for diabetes.…”
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The synthesis of azetidine and piperidine iminosugars from monosaccharides by Lenagh-Snow, G, Gabriel M.J. Lenagh-Snow

“…<p>Iminosugars are polyhydroxylated alkaloids, and can be generally defined as sugar mimetics in which the endocyclic oxygen atom has been replaced with a basic nitrogen. …”

Asymmetric fluorocyclizations of alkenes. by Wolstenhulme, JR, Gouverneur, V

“…The body of work on asymmetric fluorination using chiral cationic [NF](+) reagents prepared by fluorine transfer from the dicationic [NF](2+) reagent Selectfluor to quinuclidines, inspired the development of asymmetric F(+)-induced fluorocyclizations catalyzed by cinchona alkaloids; for catalysis, the use of N-fluorobenzenesulfonimide, which is less reactive than Selectfluor, ensures that the achiral F(+) source remains unreactive toward the alkene. …”

Characterization of the anti-inflammatory and antinociceptive activities of Erythroxylum cuneatum (Miq.) Kurz / Siti Rohani Saleh by Saleh, Siti Rohani

“…Phytochemical screening revealed that the hexane, dichloromethane, ethyl acetate and butanol extracts contained alkaloids, flavonoids, tannins and saponins. These compounds have been found to possess antioxidant properties with strong ferrous ion chelating activity (EC50: 615.9 (ig/mL) however, ECAE appeared not to have any effect on xanthine oxidase inhibitory assay. …”
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Antiproliferative mechanism of cervical cancer cells (hela) treated with biological-active subfraction from quercus infectoria extract by Abdullah, Hasmah

“…As for the phytochemical analysis of QIEA extract, it was revealed the presence of tannin, alkaloids, glycosides, saponins, terpenoids, flavonoids and phenolic compounds The QIEA extract was then purified and resulted two compounds 4-0 methylgallic acid (MGA) and gallic acid (GA). …”
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Compound Analysis of Jing Liqueur and nrf2 Activation by Jing Liqueur—One of the Most Popular Beverages in China by You-Sheng Cai, Jian Xu, Mosi Chen, Daoqing Wang, Yuejun Yang, Arulmani Manavalan, Xiaohua Wu, Yuancai Liu, Shugeng Cao

“…In conclusion, Jing liqueur contains different classes of compounds including flavonoids, terpenoids, alkaloids, coumarins, cinnamic acid or coumaric acid, and phenyl ethanol (or acetic acid) derivatives, benzoquinone, naphthoquinone, anthraquinones or phenanphrene derivatives, xanthones, chromone, and &#947;-pyrone derivatives, lignans, other aromatic compounds, and others. …”
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Copper boosts the biostimulant activity of a vegetal-derived protein hydrolysate in basil: morpho-physiological and metabolomics insights by Youssef Rouphael, Petronia Carillo, Michele Ciriello, Luigi Formisano, Christophe El-Nakhel, Paola Ganugi, Paola Ganugi, Andrea Fiorini, Begoña Miras Moreno, Leilei Zhang, Mariateresa Cardarelli, Luigi Lucini, Luigi Lucini, Giuseppe Colla

“…Consistently, the untargeted metabolomics also pointed out a distinctive modulation of phytochemical signatures as a function of the treatment. An accumulation of alkaloids, terpenoids, and phenylpropanoids was observed following Cu treatment, suggesting an oxidative imbalance upon metal exposure. …”
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Hypoglycemic, antidiabetic and toxicological evaluation of leaf extract of Xylopia parviflora (A. rich.) Benth by Farouk Adedeji Oladoja, Emmanuel S. Irokosu, Elijah O. Oyinloye, Akanji A. Murtala, Marcus D. Ayoola, Aderonke A. Aderinola, Gift Crucifix Pender, Ololade A. Popoola

“…Analysis of Variance (ANOVA) and the Dunnett multiple comparison tests were used for the statistical analysis, with a significance level of p < 0.05 Results: Preliminary phytochemical analysis of the leaf extract revealed the presence of tannins, flavonoids, saponins, alkaloids, terpenoids, deoxy-sugars, and anthraquinones. …”
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Untargeted Phytochemical Profile, Antioxidant Capacity and Enzyme Inhibitory Activity of Cultivated and Wild Lupin Seeds from Tunisia by Amna Ben Hassine, Gabriele Rocchetti, Leilei Zhang, Biancamaria Senizza, Gökhan Zengin, Mohamad Fawzi Mahomoodally, Mossadok Ben-Attia, Youssef Rouphael, Luigi Lucini, Safia El-Bok

“…Untargeted metabolomic profiling allowed to identify 249 compounds, with a great abundance of phenolics and alkaloids. In this regard, the species <i>L. cossentinii</i> showed the highest phenolic content, being 6.54 mg/g DW, followed by <i>L. luteus</i> (1.60 mg/g DW) and <i>L. albus</i> (1.14 mg/g DW). …”
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Anti-MRSA Constituents from <i>Ruta chalepensis</i> (Rutaceae) Grown in Iraq, and <i>In Silico</i> Studies on Two of Most Active Compounds, Chalepensin and 6-Hydroxy-rutin 3′,7-Dim... by Shaymaa Al-Majmaie, Lutfun Nahar, M. Mukhlesur Rahman, Sushmita Nath, Priyanka Saha, Anupam Das Talukdar, George P. Sharples, Satyajit D. Sarker

“…Phytochemical investigation afforded 19 compounds, including alkaloids, coumarins, flavonoid glycosides, a cinnamic acid derivative and a long-chain alkane. …”
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The Mechanism of Polygonum Hydropiper L-Coptis Chinensis in the Treatment of Ulcerative Colitis Based on Network Pharmacology and Experimental Validation by Feifei Zhu, Yunyun Zhi, Yonghui Li, Haiyan Niu, Shouzhong Ren

“…Study confirmed that flavonoids in PH and alkaloids in CC alleviated inflammation to inhibit the development of intestinal inflammation. …”
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