Rare Glutamic Acid Methyl Ester Peptaibols from <i>Sepedonium ampullosporum</i> Damon KSH 534 Exhibit Promising Antifungal and Anticancer Activity by Yen T. H. Lam, Manuel G. Ricardo, Robert Rennert, Andrej Frolov, Andrea Porzel, Wolfgang Brandt, Pauline Stark, Bernhard Westermann, Norbert Arnold

“…Fungal species of genus <i>Sepedonium</i> are rich sources of diverse secondary metabolites (e.g., alkaloids, peptaibols), which exhibit variable biological activities. …”
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Estudo ecogeográfico da poaia [Psychotria ipecacuanha (Brot.) Stokes] Ecogeographic study of "poaia" Psychotria ipecacuanha (Brot.) Stokes by E.R. Martins, L.O. Oliveira, J.T.L.S. Maia, I.J.C. Vieira

“…Ethnobotanical analysis consisted of a survey on therapeutic and homeopathic forms, as well as on the popular knowledge related to "poaia" use. The levels of the alkaloids emetine and cephaeline were determined using high performance liquid chromatography (HPLC). …”
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UHPLC-MS/MS phytochemical screening, polyphenolic content and antioxidant potential of Diplorhynchus condylocarpon (Müll.Arg.) Pichon (Apocynaceae), a medicinal plant by Chibuye Bitwell, Singh Indra Sen, Chimuka Luke, Maseka Kenneth Kakoma

“…The preliminary phytochemical screening revealed the presence of antioxidants, polyphenols, and other valuable phytocompounds such as alkaloids, saponins, and terpenoids. The LCMS/MS polyphenolic screening revealed the presence of mainly polyphenolic metabolites. …”
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Comparative Metabolomics Profiling Reveals Key Metabolites and Associated Pathways Regulating Tuber Dormancy in White Yam (<i>Dioscorea rotundata</i> Poir.) by Jeremiah S. Nwogha, Abtew G. Wosene, Muthurajan Raveendran, Jude E. Obidiegwu, Happiness O. Oselebe, Rohit Kambale, Cynthia A. Chilaka, Veera Ranjani Rajagopalan

“…Amines and biogenic polyamines, amino acids and derivatives, alcohols, flavonoids, alkaloids, phenols, esters, coumarins, and phytohormone positively regulated yam tuber dormancy induction and maintenance, whereas fatty acids, lipids, nucleotides, carboxylic acids, sugars, terpenoids, benzoquinones, and benzene derivatives positively regulated dormancy breaking and sprouting in tubers of both yam genotypes. …”
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<i>N</i>,<i>N</i>-Dimethyl-anthranilic Acid from <i>Calvatia nipponica</i> Mushroom Fruiting Bodies Induces Apoptotic Effects on MDA-MB-231 Human Breast Cancer Cells by Dahae Lee, Seulah Lee, Yoon Seo Jang, Rhim Ryoo, Jung Kyu Kim, Ki Sung Kang, Ki Hyun Kim

“…Bioactivity-guided fractionation of the methanol (MeOH) extract and chemical investigation of the active fractions resulted in the isolation of fourteen compounds (<b>1</b>–<b>14</b>), including six alkaloids (<b>1</b>–<b>3</b>, <b>5</b>, <b>7</b>, and <b>8</b>), two phenolic compounds (<b>4</b> and <b>6</b>), one fatty acid (<b>9</b>), and five steroids (<b>10</b>–<b>14</b>). …”
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Tap the sap – investigation of latex-bearing plants in the search of potential anticancer biopharmaceuticals by Oliwia Mazur, Sophia Bałdysz, Alicja Warowicka, Alicja Warowicka, Robert Nawrot

“…The molecules, to which this cytotoxic effect can be attributed, include alkaloids, flavonoids, tannins, terpenoids, proteases, nucleases and many novel compounds, which still remain to be characterized. …”
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Benefits of sea buckthorn juice consumption in women of productive age with hypercholesterolemia by Jana Kopčeková, Jana Mrázová, Katarína Fatrcová-Šramková, Marta Habánová, Martina Gažarová, Petra Lenártová

“…Sea buckthorn contains almost 200 nutrients and bioactive substances, including phenolic compounds such as flavonoids, vitamins, proteins, amino acids, minerals, alkaloids, chlorophyll derivatives, amines, organic acids, fatty acids and phytosterols. …”
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Bcl-xL activity influences outcome of the mitotic arrest by M. Suleimenov, S. Bekbayev, S. Bekbayev, M. Ten, M. Ten, N. Suleimenova, M. Tlegenova, A. Nurmagambetova, A. Nurmagambetova, S. Kauanova, S. Kauanova, I. Vorobjev, I. Vorobjev

“…Microtubule-targeting (MT) drugs taxanes and vinca alkaloids are widely used as chemotherapeutic agents against different tumors for more than 30 years because of their ability to block mitotic progression by disrupting the mitotic spindle and activating the spindle assembly checkpoint (SAC) for a prolonged period of time. …”
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Biochemical profiling of selected plant extracts and their antifungal activity in comparison with fungicides against Colletotrichum capsici L. causing anthracnose of Chilli by Syeda Noureen Fatima, Zarrin Fatima Rizvi, Sajjad Hyder, Amjad Shahzad Gondal, Muhammad Latif, Hafiza Mamona Nazir, Nadia Riaz, Fazal-e Habib

“…Biochemical profiling and phytochemical characterization indicated the presence of tannins, phenols, terpenoids, flavonoids, alkaloids, reducing sugars and anthraquinones in ginger and chicory extracts. …”
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The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo by Lili Cui, Chaorui Peng, Jun Li, Xin Cheng, Xiao Fan, Jingyu Li, Zixian Yang, Yuancui Zhao, Yunshu Ma

“…Ethnopharmacological relevance: Crebanine (Cre) and Stephanine (Step) are isoquinoline aporphine-type alkaloids that are extracted from Stephania yunnanenses H. …”
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Discrimination of Baphicacanthis Cusiae Rhizoma et radix and its adulterant species and establishment of an assay method for quality control by Yue Li, Qiong-Xi Yu, Lee-Fong Yau, Guo-Kai Huang, Jing-Guang Lu, Xiao-Xiao Liu, Zhi-Hong Jiang, Jing-Rong Wang

“…Results A total of 73 compounds belonging to six classes were assigned in NBLG, with alkaloids being the most abundant and diverse species. …”
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Sustainable Production of <i>N-</i>methylphenylalanine by Reductive Methylamination of Phenylpyruvate Using Engineered <i>Corynebacterium glutamicum</i> by Anastasia Kerbs, Melanie Mindt, Lynn Schwardmann, Volker F. Wendisch

“…Fermentative routes to <i>N-</i>alkylated amino acids like <i>N-</i>methyl-<span style="font-variant: small-caps;">l</span>-alanine or <i>N-</i>methylantranilate, a precursor of acridone alkaloids, have been established using engineered <i>Corynebacterium glutamicum</i>, which has been used for the industrial production of amino acids for decades. …”
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<title language="spa">Efecto antioxidante y contenido polifenólico de Syringodium filiforme (Cymodoceaceae) by Kethia L González García, Olga Valdés Iglesias, Abilio Laguna, Maylín Díaz Martínez, José Antonio González Lavaut

“…The phytochemical screening of the different extracts detected the presence of high concentrations of flavonoids, phenols, terpenes, antocyaninns, reducing sugars and alkaloids. The total extract and methanol fraction showed significant free radical scavenging properties, while the petroleum ether fraction showed moderate activity, and the chloroform fraction and the aqueous soluble precipitate (residual salt) obtained didn’t show antioxidant properties against free radicals. …”
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Amelioration of cyclophosphamide-induced DNA damage, oxidative stress, and hepato- and neurotoxicity by Piper longum extract in rats: The role of γH2AX and 8-OHdG by Vaishali Yadav, Anuja Krishnan, Sultan Zahiruddin, Sayeed Ahmad, Divya Vohora

“…Piperine and piperlongumine are the major alkaloids quantified along with the presence of flavonoids in the ethanol extract and the presence of fatty acids and terpenoids in the hexane fraction of Piper longum.Conclusion: Our investigation confirms the genoprotective action of Piper longum by reducing cyclophosphamide-associated cytogenotoxicity, oxidative stress, hepato- and neurotoxicity, oxidative DNA damage, and DNA double-strand breaks. …”
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Phytochemistry, Bioactivities, Pharmacokinetics and Toxicity Prediction of <i>Selaginella repanda</i> with Its Anticancer Potential against Human Lung, Breast and Colorectal Carcin... by Mohd Adnan, Arif Jamal Siddiqui, Walid Sabri Hamadou, Mitesh Patel, Syed Amir Ashraf, Arshad Jamal, Amir Mahgoub Awadelkareem, Manojkumar Sachidanandan, Mejdi Snoussi, Vincenzo De Feo

“…High resolution-liquid chromatography–mass spectrometry (HR-LC–MS) data of <i>S. repanda</i> crude extract revealed the presence of diverse bioactive/chemical components, including fatty acids, alcohol, sugar, flavonoids, alkaloids, terpenoids, coumarins and phenolics, which can be the basis and major cause for its bioactive potential. …”
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Gui Shao Tea Extracts Inhibit Gastric Cancer Growth in Vitro and in Vivo and Prolong Survival in Nude Mice by Yue Liu, Zhouyue Jiang, Hongwei Yang, Jingyi Yuan, Jiali Zeng, Jiayan Wu, Zhijian Xu

“…Results: The ingredients in GST, mostly terpenes and their derivatives, were novel and more concentrated than those in tea made from the branches and leaves of the same plant species, Camellia sinensis, picked and produced the same year, while the levels of polyphenols and alkaloids were significantly reduced. In BGC-823, MGC-803, and SGC-7901 gastric cancer cells, GST extracts significantly inhibited proliferation (p = 0.037), induced G0/G1 arrest (p < 0.001) and promoted early apoptosis (p = 0.041). …”
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Factors associated with acute medication overuse in people with migraine: results from the 2017 migraine in America symptoms and treatment (MAST) study by Todd J. Schwedt, Aftab Alam, Michael L. Reed, Kristina M. Fanning, Sagar Munjal, Dawn C. Buse, David W. Dodick, Richard B. Lipton

“…Compared with those not overusing medications, respondents with AMO were significantly more likely to be taking triptans (31.3% vs 14.2%), opioids (23.8% vs 8.0%), barbiturates (7.8% vs 2.7%), and ergot alkaloids (3.1% vs 0.6%) and significantly less likely to be taking NSAIDs (63.3% vs 69.8%) (p < 0.001 for all comparisons). …”
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Evaluation of Antioxidant Properties and Cytotoxic Effect of Scutellaria Pinnatifida Extract on Survival and Expression of Genes Involved in Cell Cycle (P53 and CDK2) in Kidney Can... by Zahra Pakravan, Narges Nikoonahad Lotfabadi, Seyed Mohsen Miresmaeili

“…Results: According to the results obtained from the phytochemical tests, the spike plate plant extract contains flavonoids, triterpenoids, asteroids, sterols, and glycosides, but it does not contain alkaloids, tannins, and saponins. MTT assay showed that Scutellaria pinnatifida extract has a lethal effect on ACHN cells and this effect is dose and time-dependent. …”
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De novo sequencing, assembly, and characterization of Asparagus racemosus transcriptome and analysis of expression profile of genes involved in the flavonoid biosynthesis pathway by Chanchal Malik, Sudhanshu Dwivedi, Tilahun Rabuma, Tilahun Rabuma, Ravinder Kumar, Nitesh Singh, Anil Kumar, Rajesh Yogi, Vinod Chhokar

“…Asparagus racemosus is known for its diverse content of secondary metabolites, i.e., saponins, alkaloids, and a wide range of flavonoids. Flavonoids, including phenols and polyphenols, have a significant role in plant physiology and are synthesized in several tissues. …”
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Evaluation of Antimicrobial and Anticancer Activities of Selected Medicinal Plants of Himalayas, Pakistan by Farzana Kausar, Kyung-Hwan Kim, Hafiz Muhammad Umer Farooqi, Muhammad Awais Farooqi, Muhammad Kaleem, Rooma Waqar, Atif Ali Khan Khalil, Fazli Khuda, Chethikkattuveli Salih Abdul Rahim, Kinam Hyun, Kyung-Hyun Choi, Abdul Samad Mumtaz

“…The preliminary phytochemical screening showed the presence of secondary metabolites such as alkaloids, tannins, saponins, flavonoids, glycosides, and quinones. …”
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