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Alkaloids from Piper sarmentosum and Piper nigrum
Published 2009“…Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids. The roots of P. sarmentosum gave a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1). …”
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Dicentrine: The Major Alkaloid of Cyclea laxiflara Miers
Published 1991“…The major alkaloid of Cyclea laxiflora Miers. was isolated and identified as dicentrine from its spectral and physical data.…”
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Alkaloids from Piper nigrum and Piper betle
Published 2009“…An investigation, on the roots of Piper nigrum and the aerial parts of Piper betle, has yielded several alkaloids. The dried root sample of Piper nigrum was extracted using various solvents in increasing polarity. …”
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Hispidacine, an unusual 8,4′-oxyneolignan-alkaloid with vasorelaxant activity, and hispiloscine, an antiproliferative phenanthroindolizidine alkaloid, from Ficus hispida Linn.
Published 2015“…Hispidacine, an 8,4′-oxyneolignan featuring incorporation of an unusual 2-hydroxyethylamine moiety at C-7, and hispiloscine, a phenanthroindolizidine alkaloid, were isolated from the stem-bark and leaves of the Malaysian Ficus hispida Linn. …”
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The synthesis of 4-substituted indoles and their elaboration to the ergot alkaloids
Published 2005Subjects: Get full text
Thesis -
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Human alkaloid biosynthesis : chemical inducers of Parkinson's disease?
Published 2007Get full text
Thesis -
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Substrate analogs to investigate alkaloid biosynthesis in Catharanthus roseus
Published 2009Get full text
Thesis -
69
Opportunities in metabolic engineering to facilitate scalable alkaloid production
Published 2012“…In this Perspective, we discuss the opportunities and challenges of implementing metabolic engineering in various platforms for the synthesis of natural and unnatural plant alkaloids.…”
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Dimerization of functional pyrroloindolizines for the synthesis of complex myrmicarin alkaloids
Published 2012“…The union of functionalized pyrroloindolizines for the synthesis of heterodimeric products relevant to myrmicarin alkaloids is described. Design and synthesis of tricyclic substrates and new methods for their union enable the investigation of late-stage cyclopentannulation strategies. …”
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Synthesis and Anticancer Activity of All Known (−)-Agelastatin Alkaloids
Published 2015“…Our concise synthesis of these alkaloids exploits the intrinsic chemistry of plausible biosynthetic precursors and capitalizes on a late-stage synthesis of the C-ring. …”
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Aza-Tryptamine Substrates in Monoterpene Indole Alkaloid Biosynthesis
Published 2015“…Here we have altered tryptamine, which serves as the starting substrate for a variety of alkaloid biosynthetic pathways, by replacing the indole with one of four aza-indole isomers. …”
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Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids
Published 2015“…It is with this ethos that our group has taken an interest in and pursued the synthesis of a complex family of natural products termed the dimeric epipolythiodiketopiperazine (ETP) alkaloids. We present here an Account of the highly complex target molecules to which we pegged our ambitions, our systematic and relentless efforts toward those goals, the chemistry we developed in their pursuit, and the insight we have gained for their translational potential as potent anticancer molecules.…”
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Synthesis of the sedum and related alkaloids : a personal perspective
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Cytotoxicity and antimicrobial activities of alkaloid from Tabernaemontana corymbosa
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Cytotoxic and antimicrobial activities of alkaloids from tabernaemontana corymbosa
Published 2011“…The investigations were made based on the fact that alkaloids from Apocynaceae family are potential for medicinal purposes. …”
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Benzyltetrahydroisoquinoline and bis-benzyltetrahydroisoquinoline alkaloids as anti-parasitic agents
Published 2023Subjects:Thesis -
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