Direct endothelial ENaC activation mitigates vasculopathy induced by SARS-CoV2 spike protein by Maritza J. Romero, Maritza J. Romero, Qian Yue, Bhupesh Singla, Jürg Hamacher, Jürg Hamacher, Jürg Hamacher, Supriya Sridhar, Auriel S. Moseley, Chang Song, Mobarak A. Mraheil, Bernhard Fischer, Markus Zeitlinger, Trinad Chakraborty, David Fulton, David Fulton, Lin Gan, Brian H. Annex, Gabor Csanyi, Gabor Csanyi, Douglas C. Eaton, Rudolf Lucas, Rudolf Lucas, Rudolf Lucas, Rudolf Lucas

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Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer Via Downregulation of Nuclear p65 and HIF-1α by Alaa A. A. Aljabali, Hamid A. Bakshi, Faruck L. Hakkim, Yusuf A. Haggag, Khalid M. Al-Batanyeh, Mazhar S. Al Zoubi, Bahaa Al-Trad, Mohamed M. Nasef, Saurabh Satija, Meenu Mehta, Kavita Pabreja, Vijay Mishra, Mohammed Khan, Salem Abobaker, Ibrahim M. Azzouz, Harish Dureja, Ritesh M. Pabari, Ashref Ali K. Dardouri, Prashant Kesharwani, Gaurav Gupta, Shakti Dhar Shukla, Parteek Prasher, Nitin B. Charbe, Poonam Negi, Deepak N. Kapoor, Dinesh Kumar Chellappan, Mateus Webba da Silva, Paul Thompson, Kamal Dua, Paul McCarron, Murtaza M. Tambuwala

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LIONS PREY: A New Logistic Scoring System for the Prediction of Malignant Pulmonary Nodules by Fabian Doerr, Annika Giese, Katja Höpker, Hruy Menghesha, Georg Schlachtenberger, Konstantinos Grapatsas, Natalie Baldes, Christian J. Baldus, Lars Hagmeyer, Hazem Fallouh, Daniel Pinto dos Santos, Edward M. Bender, Alexander Quaas, Matthias Heldwein, Thorsten Wahlers, Hubertus Hautzel, Kaid Darwiche, Christian Taube, Martin Schuler, Khosro Hekmat, Servet Bölükbas

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Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening by Florian Milatz, Jens Klotsche, Martina Niewerth, Claudia Sengler, Daniel Windschall, Tilmann Kallinich, Frank Dressler, Ralf Trauzeddel, Reinhard W. Holl, Ivan Foeldvari, Normi Brück, Svenja Temming, Toni Hospach, Petra Warschburger, Rainer Berendes, Gabriele Erbis, Jasmin B. Kuemmerle-Deschner, Frank Weller-Heinemann, Johannes-Peter Haas, Annabel S. Müller-Stierlin, Agnes Mutter, Thomas Meissner, Harald Baumeister, Kirsten Minden

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Meta-Analysis of Mutations in <i>ALOX12B</i> or <i>ALOXE3</i> Identified in a Large Cohort of 224 Patients by Alrun Hotz, Julia Kopp, Emmanuelle Bourrat, Vinzenz Oji, Katalin Komlosi, Kathrin Giehl, Bakar Bouadjar, Anette Bygum, Iliana Tantcheva-Poor, Maritta Hellström Pigg, Cristina Has, Zhou Yang, Alan D. Irvine, Regina C. Betz, Giovanna Zambruno, Gianluca Tadini, Kira Süßmuth, Robert Gruber, Matthias Schmuth, Juliette Mazereeuw-Hautier, Natalie Jonca, Sophie Guez, Michela Brena, Angela Hernandez-Martin, Peter van den Akker, Maria C. Bolling, Katariina Hannula-Jouppi, Andreas D. Zimmer, Svenja Alter, Anders Vahlquist, Judith Fischer

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Sustained Effectiveness of Benralizumab in Na&iuml;ve and Biologics-Experienced Severe Eosinophilic Asthma Patients: Results from the ANANKE Study by Cameli P, Aliani M, Altieri E, Bracciale P, Brussino L, Caiaffa MF, Canonica GW, Caruso C, Centanni S, D'Amato M, De Michele F, Del Giacco S, Di Marco F, Pelaia G, Rogliani P, Romagnoli M, Schino P, Schroeder JW, Senna G, Vultaggio A, Benci M, Boarino S, Menzella F

“…Garbagnate Milanese, Garbagnate Milanese (MI), Italy; 4Reparto di Pneumologia, Ospedale Ostuni, Ostuni (BR), Italy; 5Dipartimento di Scienze Mediche, Università degli Studi di Torino; SCDU Immunologia e Allergologia, AO Ordine Mauriziano Umberto I, Torino, Italy; 6Cattedra e Scuola di Allergologia e Immunologia Clinica, Dipartimento di Scienze Mediche, Università di Foggia, Foggia, Italy; 7Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (MI), Italy; 8Personalized Medicine Center: Asthma and Allergology, Humanitas Research Hospital, Rozzano (MI), Italy; 9Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico A. …”
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Postoperative Tobacco Cessation Improves Quality of Life, Lung Function and Long-Term Survival in Non-Small-Cell Lung Cancer Patients by Fabian Doerr, Tobias Leschczyk, Konstantinos Grapatsas, Hruy Menghesha, Natalie Baldes, Georg Schlachtenberger, Matthias B. Heldwein, Maximilian Michel, Alexander Quaas, Lars Hagmeyer, Katja Höpker, Thorsten Wahlers, Kaid Darwiche, Christian Taube, Martin Schuler, Khosro Hekmat, Servet Bölükbas

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Immunogenicity and Safety of a Combined Intramuscular/Intranasal Recombinant Spike Protein COVID-19 Vaccine (RCP) in Healthy Adults Aged 18 to 55 Years Old: A Randomized, Double-Bl... by Masoud Solaymani Dodaran, Seyed Reza Banihashemi, Ali Es-haghi, Mohammad Hossein Fallah Mehrabadi, Mojtaba Nofeli, Ali Rezaei Mokarram, Ladan Mokhberalsafa, Fariba Sadeghi, Alireza Ranjbar, Akram Ansarifar, Arash Mohazzab, Seyed Amin Setarehdan, Fahimeh Bagheri Amiri, Vahideh Mohseni, Monireh Hajimoradi, Neda Ghahremanzadeh, Seyed Hossein Razzaz, Safdar Masoomi, Maryam Taghdiri, Mohsen Bagheri, Mohsen Lofti, Akbar Khorasani, Masoud Ghader, Shiva Safari, Masumeh Shahsavn, Saeed Kalantari

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The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey by Casper M. Kersten, Sergei M. Hermelijn, Dhanya Mullassery, Nagarajan Muthialu, Nazan Cobanoglu, Silvia Gartner, Pietro Bagolan, Carmen Mesas Burgos, Alberto Sgrò, Stijn Heyman, Holger Till, Janne Suominen, Maarten Schurink, Liesbeth Desender, Paul Losty, Henri Steyaert, Suzanne Terheggen-Lagro, Martin Metzelder, Arnaud Bonnard, Rony Sfeir, Michael Singh, Iain Yardley, Noor R. V. M. Rikkers-Mutsaerts, Cornelis K. van der Ent, Niels Qvist, Des W. Cox, Robert Peters, Michiel A. G. E. Bannier, Lucas Wessel, Marijke Proesmans, Michael Stanton, Edward Hannon, Marco Zampoli, Francesco Morini, Harm A. W. M. Tiddens, René M. H. Wijnen, Johannes M. Schnater

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Still’s disease continuum from childhood to elderly: data from the international AIDA Network Still’s disease registry by Micol Frassi, Marcello Govoni, Annamaria Iagnocco, Florenzo Iannone, Paola Triggianese, Corrado Campochiaro, Sara Monti, Maria G Tektonidou, Eduardo Martin-Nares, Piero Ruscitti, Roberto Giacomelli, Luca Cantarini, Giuseppe Lopalco, Lorenzo Dagna, Francesco Carubbi, Alma Nunzia Olivieri, Antonio Vitale, Ombretta Viapiana, Fatma Alibaz-Öner, Haner Direskeneli, Petros P Sfikakis, Giacomo Emmi, Claudia Fabiani, Gabriele Simonini, Francesco Ciccia, Elena Bartoloni, Alessandro Tomelleri, Daniela Iacono, Riza Can Kardas, Bruno Frediani, Benson Ogunjimi, Amato de Paulis, Onorina Berardicurti, Alessandro Conforti, Ilenia Di Cola, Anastasios Karamanakos, Katerina Laskari, Abdurrahman Tufan, Stefania Costi, José Hernández-Rodríguez, Lampros Fotis, Jurgen Sota, Antonio Gidaro, Ewa Wiesik-Szewczyk, Gian Domenico Sebastiani, Jiram Torres-Ruiz, Paolo Sfriso, Giovanni Conti, Luca Navarini, Francesco La Torre, Samar Tharwat, Andrea Hinojosa-Azaola, Alberto Lo Gullo, Valeria Caggiano, Ibrahim A Almaghlouth, Kazi Asfina, Gafaar Ragab, Maria Cristina Maggio, Joanna Makowska, Emanuela Del Giudice, Armin Maier, Sukran Erten, Henrique A Mayrink Giardini, Maria Morrone, Isabele Parente de Brito Antonelli, Marilia Ambiel Dagostin, Martina Patrone, Fehaid Alanazi, Carla Gaggiano, Hamit Kucuk, Ayman Abdel-Monem Ahmed Mahmoud, Katerina Kourtesi, Maria Tarsia, Verónica Gómez-Caverzaschi, Angela Mauro, Alberto Balistreri

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Outcome Prediction in Patients with Severe COVID-19 Requiring Extracorporeal Membrane Oxygenation—A Retrospective International Multicenter Study by Alexander Supady, Jeff DellaVolpe, Fabio Silvio Taccone, Dominik Scharpf, Matthias Ulmer, Philipp M. Lepper, Maximilian Halbe, Stephan Ziegeler, Alexander Vogt, Raj Ramanan, David Boldt, Stephanie-Susanne Stecher, Andrea Montisci, Tobias Spangenberg, Olivier Marggraf, Chandra Kunavarapu, Lorenzo Peluso, Sebastian Muenz, Monica Buerle, Naveen G. Nagaraj, Sebastian Nuding, Catalin Toma, Vadim Gudzenko, Hans Joachim Stemmler, Federico Pappalardo, Georg Trummer, Christoph Benk, Guido Michels, Daniel Duerschmied, Constantin von zur Muehlen, Christoph Bode, Klaus Kaier, Daniel Brodie, Tobias Wengenmayer, Dawid L. Staudacher

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Clinical Features and Efficacy of Benralizumab in Patients with Blood Eosinophil Count Between 300 and 450 Cells/mm3: A Post Hoc Analysis from the ANANKE Study by Senna G, Aliani M, Altieri E, Bracciale P, Brussino L, Caiaffa MF, Cameli P, Canonica GW, Caruso C, D'Amato M, De Michele F, Del Giacco S, Di Marco F, Menzella F, Pelaia G, Rogliani P, Romagnoli M, Schino P, Schroeder JW, Vultaggio A, Rizzoli S, Zullo A, Boarino S, Palmisano M, Rossi A, Vitiello G, Centanni S

“…Gianenrico Senna,1,2 Maria Aliani,3 Elena Altieri,4 Pietro Bracciale,5 Luisa Brussino,6 Maria Filomena Caiaffa,7 Paolo Cameli,8 Giorgio Walter Canonica,9,10 Cristiano Caruso,11 Maria D’Amato,12 Fausto De Michele,13 Stefano Del Giacco,14 Fabiano Di Marco,15 Francesco Menzella,16 Girolamo Pelaia,17 Paola Rogliani,18,19 Micaela Romagnoli,20 Pietro Schino,21 Jan Walter Schroeder,22 Alessandra Vultaggio,23 Sara Rizzoli,24 Alessandro Zullo,24 Silvia Boarino,25 Marilena Palmisano,26 Alessandra Rossi,26 Gianfranco Vitiello,26 Stefano Centanni27 1Department of Medicine, University of Verona, Verona, Italy; 2Allergy Unit and Asthma Center, Verona University Hospital, Verona, Italy; 3UO Pneumologia e Pneumologia Riabilitativa, ICS Maugeri, IRCCS Bari, Bari, Italy; 4Reparto di Pneumologia, P.O., Garbagnate Milanese, Italy; 5Reparto di Pneumologia, Ospedale Ostuni, Ostuni, BR, Italy; 6Dipartimento di Scienze Mediche, SSDDU Allergologia e Immunologia Clinica, Università degli Studi di Torino, AO Ordine Mauriziano Umberto I, Torino, Italy; 7Cattedra e Scuola di Allergologia e Immunologia Clinica, Dipartimento di Scienze Mediche, Università di Foggia, Foggia, Italy; 8Respiratory Diseases and Lung Transplantation, Department of Medical and Surgical Sciences & Neurosciences, Siena University Hospital, Siena, Italy; 9Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy; 10Personalized Medicine Center: Asthma and Allergology, Humanitas Research Hospital, Rozzano, MI, Italy; 11Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico A. …”
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Metabolic Profiling at COVID-19 Onset Shows Disease Severity and Sex-Specific Dysregulation by Francisco C. Ceballos, Ana Virseda-Berdices, Salvador Resino, Salvador Resino, Pablo Ryan, Pablo Ryan, Oscar Martínez-González, Oscar Martínez-González, Felipe Peréz-García, Felipe Peréz-García, María Martin-Vicente, María Martin-Vicente, Oscar Brochado-Kith, Oscar Brochado-Kith, Rafael Blancas, Rafael Blancas, Sofía Bartolome-Sánchez, Erick Joan Vidal-Alcántara, Oihane Elena Albóniga-Díez, Juan Cuadros-González, Juan Cuadros-González, Natalia Blanca-López, Isidoro Martínez, Isidoro Martínez, Ignacio Ramirez Martinez-Acitores, Coral Barbas, Amanda Fernández-Rodríguez, Amanda Fernández-Rodríguez, María Ángeles Jiménez-Sousa, María Ángeles Jiménez-Sousa

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Current expert opinion and attitudes to optimize telemedicine and achieve control in patients with asthma in post-pandemic era: The COMETA consensus by Jesús Molina Paris, Carlos Almonacid Sánchez, Marina Blanco-Aparicio, Javier Domínguez-Ortega, Jordi Giner Donaire, Navidad Sánchez Marcos, Vicente Plaza

“…Participants: A pre-selected sample of 75 experts with experience in telemedicine (pulmonology, allergology, family medicine, nursing and community pharmacy) responded to a Delphi-like questionnaire composed by six questions and 52 items. …”
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Mollusk allergy in shrimp-allergic patients: Still a complex diagnosis. An Italian real-life cross-sectional multicenter study by Enrico Scala, MD, Damiano Abeni, MD, Arianna Aruanno, MD, Elisa Boni, MD, Ignazio Brusca, MD, Francesca Cappiello, MD, Elisabetta Caprini, BD, Francesca Buzzulini, MD, Gaia Deleonardi, MD, Antongiulio Demonte, MD, Laura Farioli, MD, Fabio Lodi Rizzini, MD, Laura Michelina Losappio, MD, Donatella Macchia, MD, Giuseppina Manzotti, MD, Giorgia Meneguzzi, MD, Marcello Montagni, MD, Eleonora Nucera, MD, Rosa Onida, MD, Elide Anna Pastorello, MD, Silvia Peveri, MD, Anna Radice, MD, Federica Rivolta, MD, Angela Rizzi, MD, Mauro Giani, MD, Lorenzo Cecchi, MD, Elena Pinter, MD, Marzia Miglionico, MD, Lorenzo Vantaggio, MD, Valerio Pravettoni, MD, Danilo Villalta, MD, Riccardo Asero, MD

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Post hoc analysis examining symptom severity reduction and symptom absence during food challenges in individuals who underwent oral immunotherapy for peanut allergy: results from t... by Katharina Blumchen, Andreas Kleinheinz, Ludger Klimek, Kirsten Beyer, Aikaterini Anagnostou, Christian Vogelberg, Sergejus Butovas, Robert Ryan, David Norval, Stefan Zeitler, George Du Toit

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A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifies ANXA1 as a susceptibility locus for persistent wheezing by Raquel Granell, John A Curtin, Sadia Haider, Negusse Tadesse Kitaba, Sara A Mathie, Lisa G Gregory, Laura L Yates, Mauro Tutino, Jenny Hankinson, Mauro Perretti, Judith M Vonk, Hasan S Arshad, Paul Cullinan, Sara Fontanella, Graham C Roberts, Gerard H Koppelman, Angela Simpson, Steve W Turner, Clare S Murray, Clare M Lloyd, John W Holloway, Adnan Custovic, on behalf of UNICORN and Breathing Together investigators

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Serial echocardiographic evaluation of COVID-19 patients without prior history of structural heart disease: a 1-year follow-up CRACoV-HHS study by Agnieszka Olszanecka, Agnieszka Olszanecka, Wiktoria Wojciechowska, Wiktoria Wojciechowska, Agnieszka Bednarek, Piotr Kusak, Barbara Wizner, Barbara Wizner, Michał Terlecki, Michał Terlecki, Katarzyna Stolarz-Skrzypek, Katarzyna Stolarz-Skrzypek, Marek Klocek, Marek Klocek, Tomasz Drożdż, Tomasz Drożdż, Krzysztof Sładek, Krzysztof Sładek, Monika Bociąga-Jasik, Monika Bociąga-Jasik, Aleksander Garlicki, Aleksander Garlicki, Krzysztof Rewiuk, Krzysztof Rewiuk, Andrzej Matyja, Andrzej Matyja, Maciej Małecki, Maciej Małecki, Wojciech Sydor, Wojciech Sydor, Wojciech Sydor, Marcin Krzanowski, Marcin Krzanowski, Tomasz Grodzicki, Tomasz Grodzicki, Marek Rajzer, Marek Rajzer

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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation by Ashley Budu-Aggrey, Anna Kilanowski, Maria K. Sobczyk, 23andMe Research Team, Suyash S. Shringarpure, Ruth Mitchell, Kadri Reis, Anu Reigo, Estonian Biobank Research Team, Reedik Mägi, Mari Nelis, Nao Tanaka, Ben M. Brumpton, Laurent F. Thomas, Pol Sole-Navais, Christopher Flatley, Antonio Espuela-Ortiz, Esther Herrera-Luis, Jesus V. T. Lominchar, Jette Bork-Jensen, Ingo Marenholz, Aleix Arnau-Soler, Ayoung Jeong, Katherine A. Fawcett, Hansjorg Baurecht, Elke Rodriguez, Alexessander Couto Alves, Ashish Kumar, Patrick M. Sleiman, Xiao Chang, Carolina Medina-Gomez, Chen Hu, Cheng-jian Xu, Cancan Qi, Sarah El-Heis, Philip Titcombe, Elie Antoun, João Fadista, Carol A. Wang, Elisabeth Thiering, Baojun Wu, Sara Kress, Dilini M. Kothalawala, Latha Kadalayil, Jiasong Duan, Hongmei Zhang, Sabelo Hadebe, Thomas Hoffmann, Eric Jorgenson, Hélène Choquet, Neil Risch, Pål Njølstad, Ole A. Andreassen, Stefan Johansson, Catarina Almqvist, Tong Gong, Vilhelmina Ullemar, Robert Karlsson, Patrik K. E. Magnusson, Agnieszka Szwajda, Esteban G. Burchard, Jacob P. Thyssen, Torben Hansen, Line L. Kårhus, Thomas M. Dantoft, Alexander C.S.N. Jeanrenaud, Ahla Ghauri, Andreas Arnold, Georg Homuth, Susanne Lau, Markus M. Nöthen, Norbert Hübner, Medea Imboden, Alessia Visconti, Mario Falchi, Veronique Bataille, Pirro Hysi, Natalia Ballardini, Dorret I. Boomsma, Jouke J. Hottenga, Martina Müller-Nurasyid, Tarunveer S. Ahluwalia, Jakob Stokholm, Bo Chawes, Ann-Marie M. Schoos, Ana Esplugues, Mariona Bustamante, Benjamin Raby, Syed Arshad, Chris German, Tõnu Esko, Lili A. Milani, Andres Metspalu, Chikashi Terao, Katrina Abuabara, Mari Løset, Kristian Hveem, Bo Jacobsson, Maria Pino-Yanes, David P. Strachan, Niels Grarup, Allan Linneberg, Young-Ae Lee, Nicole Probst-Hensch, Stephan Weidinger, Marjo-Riitta Jarvelin, Erik Melén, Hakon Hakonarson, Alan D. Irvine, Deborah Jarvis, Tamar Nijsten, Liesbeth Duijts, Judith M. Vonk, Gerard H. Koppelmann, Keith M. Godfrey, Sheila J. Barton, Bjarke Feenstra, Craig E. Pennell, Peter D. Sly, Patrick G. Holt, L. Keoki Williams, Hans Bisgaard, Klaus Bønnelykke, John Curtin, Angela Simpson, Clare Murray, Tamara Schikowski, Supinda Bunyavanich, Scott T. Weiss, John W. Holloway, Josine L. Min, Sara J. Brown, Marie Standl, Lavinia Paternoster

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Harmonizing allergy care–integrated care pathways and multidisciplinary approaches by Lydia Daniels, BSc, Sally Barker, BSc, Yoon-Seok Chang, MD, PhD, Tinatin Chikovani, MD, PhD, Audrey DunnGalvin, PhD, Jennifer D. Gerdts, BComm, Roy Gerth Van Wijk, MD, PhD, Trevor Gibbs, MB. ChB, MD, Rosalaura V. Villarreal-Gonzalez, MD, Rosa I. Guzman-Avilan, MD, MHA, Heather Hanna, MSc, Elham Hossny, MD, PhD, Anastasia Kolotilina, MD, José Antonio Ortega Martell, MD, Punchama Pacharn, MD, Cindy E. de Lira Quezada, MD, Elopy Sibanda, MD, PhD, David Stukus, MD, Elizabeth Huiwen Tham, MBBS, MRCPCH, Carina Venter, PhD, RD, Sandra N. Gonzalez-Diaz, MD, PhD, Michael E. Levin, MD, PhD, Bryan Martin, DO, Daniel Munblit, MD, PhD, John O. Warner, MD

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