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181
Analysis of radiation shielding effectiveness of hydride and borohydride metals for nuclear industry
Published 2023-03-01“…Secondly, the charged particle (electron, proton and alpha particle) interactions were examined by using ESTAR (Stopping Powers and Ranges for Electrons) and SRIM (The Stopping and Range of Ions in Matter) programs. …”
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182
Human epidermal growth factor receptor 2 expression in women with uterine cervix adenocarcinoma from Appalachian Kentucky
Published 2023-01-01“…IntroductionHigh-risk human epidermal growth factor receptor 2 (HER2)-positive adenocarcinomas associate with early recurrence and death, prompting consideration of novel radiotherapeutic options like a trastuzumab-linked thorium-227 alpha-particle emitting radionuclide.MethodsWe conducted a retrospective pilot biomarker study of uterine cervix cancers among patients in Appalachian Kentucky, to characterize an exploitable triage biomarker like HER2 expression before starting a prospective phase 0 trial.ResultsMost (60%) adenocarcinomas showed HER2 cell-surface overexpression, whereas squamous cell carcinomas (4%) did not do so.DiscussionFurther validation tests of HER2 expression as a triage biomarker for radiopharmaceutical selection are warranted.…”
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183
<sup>6</sup>LiF Converters for Neutron Detection: Production Procedures and Detector Tests
Published 2022-12-01“…Several methods to detect thermal neutrons make use of the naturally occurring <sup>6</sup>Li isotope, as it has a rather high cross-section for neutron capture followed by a decay into an alpha particle and a triton. Due to the high chemical reactivity of lithium, the use of the stable isotopic salt <sup>6</sup>LiF is generally preferred to the pure <sup>6</sup>Li. …”
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184
Does the Mott problem extend to Geiger counters?
Published 2023-10-01“…The Mott problem is a simpler version of the quantum measurement problem that asks: Is there a microscopic physical mechanism – based (explicitly or implicitly) only on Schroedinger’s equation – that explains why a single alpha particle emitted in a single spherically symmetric s-wave nuclear decay produces a manifestly nonspherically symmetric single track in a cloud chamber? …”
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185
Proton and alpha radiation-induced mutational profiles in human cells
Published 2023-06-01“…To this end, we exposed cultured cell lines from the human blood, breast and lung to fractionated proton and alpha particle (helium nuclei) beams at doses sufficient to considerably affect cell viability. …”
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186
Thoron activity concentration in Malaysian soil gas: geogenic impact assessment
Published 2022“…Nevertheless, in a thorium (232Th) rich environment potential hazard does exist, in particular regarding prolonged duration exposures to 220Rn and its short-lived alpha-particle emitting progeny [polonium (216Po)]. Herein, concerning the geology and major soil types in the Malaysian state of Perak, an activity concentration map has been established for 220Rn in soil gas, with the use made of a RAD7 detector and the THORON protocol for in-situ measurements. …”
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187
Effects of ion composition on escape and morphology on Mars
Published 2023-09-01“…Here, we investigate in a case study the effects on escape estimates of assumed ionospheric ion composition, solar-wind alpha-particle concentration and temperature, solar-wind velocity aberration, and solar-wind electron temperature. …”
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Assessment of radium and supported radon in ground water from Cameron Highlands area / Nor Shazlina Zainal
Published 2014“…If this water is inhaled or ingested by human, they may be exposed to the emission of energetic alpha particle from radium and supported 222Rn decaying process in this water. …”
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190
Tumor growth inhibition and immune system activation following treatment with thorium-227 conjugates and PD-1 check-point inhibition in the MC-38 murine model
Published 2022-11-01“…The radiolabeled conjugate functions as an effective delivery system of alpha-particle radiation to the surface of the tumor cell inducing difficult to repair complex DNA damage and cell death. …”
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191
Efficacy of Transistor Interleaving in DICE Flip-Flops at a 22 nm FD SOI Technology Node
Published 2022-04-01“…Comparisons were made between a standard DICE design and two other designs making use of the new Continuous Active (CnRx) Diffusion construct and guard-gate transistor stacking through alpha particle and heavy ion irradiation. Designs making use of the CnRx construct for performance improvements were more likely to experience upsets due to higher collected charges in the increased diffusion regions. …”
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192
Updates to TRACK_TEST and TRACK_VISION Computer Programs
Published 2021-02-01“…Discrepancies were within ~10% and <14% for incident alpha-particle energies of 1 MeV and >1 MeV, respectively. …”
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193
Recent preclinical and clinical advances in radioimmunotherapy for non-Hodgkin’s lymphoma
Published 2024-02-01“…RIT is constantly evolving with the identification of novel targets and novel therapeutic strategies using newer radionuclides such as alpha-particle isotopes. Alpha-particles show very short path lengths and high linear energy transfer. …”
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194
Alpha Radiation-Induced Luminescence by Am-241 in Aqueous Nitric Acid Solution
Published 2019-04-01“…When exposed to air, alpha particles cause the production of light by exciting the molecules surrounding them. …”
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195
Effect of the Synthesis Conditions on the Morphology, Luminescence and Scintillation Properties of a New Light Scintillation Material Li<sub>2</sub>CaSiO<sub>4</sub>:Eu<sup>2+</sup...
Published 2022-08-01“…These properties and the transparency in the visible spectrum make it possible to produce scintillation screens with a coating of Li<sub>2</sub>CaSiO<sub>4</sub> for detecting neutrons, alpha particles and low-energy beta radiation. The low Z<sub>eff</sub> (~15) of this compound makes it less sensitive to gamma rays. …”
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196
Oxidation of <i>p</i>-[<sup>125</sup>I]Iodobenzoic Acid and <i>p</i>-[<sup>211</sup>At]Astatobenzoic Acid Derivatives and Evaluation In Vivo
Published 2022-09-01“…The alpha particle-emitting radionuclide astatine-211 (<sup>211</sup>At) is of interest for targeted radiotherapy; however, low in vivo stability of many <sup>211</sup>At-labeled cancer-targeting molecules has limited its potential. …”
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197
Ion pulse ionization chamber for online measurements of the radon activity concentration
Published 2021-04-01“…The radon content in the air was measured in different locations, and the effective signals and counts were obtained.Results & ConclusionsThe measurement results show that the full width at half maximum (FWHM) of the 241Am alpha particle energy resolution is 17% under the detector's working voltage range of -400 to -1 200 V. …”
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198
Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy
Published 2024-01-01“…The radiation detection performance of prototypes has been tested by ion beam induced charge (IBIC) microscopy using a 5.5 MeV alpha particle microbeam. We also carried out the HDR Ir-192 radiation source tracking at different depths and angular dose dependence in a water equivalent phantom. …”
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199
Effect of proton irradiation induced localized defect clusters on recovery time and leakage current in silicon photoconductive semiconductor switches
Published 2023-10-01“…For decades, fabrication and irradiation techniques, such as Au- and Pt-diffusion, and energized electron-, proton-, and alpha particle-beam bombardment have been used to adjust minority carrier lifetime in silicon. …”
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200
A model for the Global Quantum Efficiency for a TPB-based wavelength-shifting system used with photomultiplier tubes in liquid argon in MicroBooNE
Published 2019“…We compare results from four measurements of the NPE determined using alpha-particle sources placed at two distances from a TPB-coated plate in a liquid argon cryostat test stand. …”
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