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261
Mitigation of Single Event Upset Effects in Nanosheet FET 6T SRAM Cell
Published 2024-01-01“…The effects of single event upset (SEU) by alpha particles and heavy ions on the data flip of a 3 nm technology node gate-all-around (GAA) nanosheet field-effect transistor (NSFET) 6T static random-access memory (SRAM) cell was studied through technology computer-aided design (TCAD) simulations. …”
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262
Ultrastructural Analysis of Cancer Cells Treated with the Radiopharmaceutical Radium Dichloride ([<sup>223</sup>Ra]RaCl<sub>2</sub>): Understanding the Effect on Cell Structure
Published 2023-01-01“…The use of alpha-particle (α-particle) radionuclides, especially [<sup>223</sup>Ra]RaCl<sub>2</sub> (radium dichloride), for targeted alpha therapy is steadily increasing. …”
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263
Nicotine interacts with DNA lesions induced by alpha radiation which may contribute to erroneous repair in human lung epithelial cells
Published 2024-10-01“…Nicotine had a modest effect on reactive oxygen species induction, but tended to increase alpha particle-induced pro-inflammatory IL-6 and IL-1β (4 Gy). …”
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264
Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma
Published 2022-11-01“…The efficacy and toxicity of the PARP inhibitor parthanatine, radiolabeled with the alpha particle emitter astatine-211, in 11 patient derived neuroblastoma murine xenografts is investigated.…”
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265
Search for toroids in excited nuclear material
Published 2024-01-01“…This potential evidence for toroidal states was reported in the alpha particle disassembly of 28Si after collision with a 12C target at 35 MeV/nucleon. …”
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266
Estimation of relative biological effectiveness of 225Ac compared to 177Lu during [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy using TOPAS/TOPAS-nBio/MEDRAS
Published 2023-09-01“…Abstract Aim Over recent years, [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy have evolved as a promising treatment option for advanced prostate cancer. Especially for alpha particle emitter treatments, there is still a need for improving dosimetry, which requires accurate values of relative biological effectiveness (RBE). …”
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267
Isotope effects and Alfvén eigenmode stability in JET H, D, T, DT, and He plasmas
Published 2024-01-01“…In particular, if radiative damping plays a significant role in overall stability, some AEs could be more easily destabilized in D/T plasmas than their H/He reference pulses, even before considering fast ion and alpha particle drive. Active MHD spectroscopy is also employed on select HD, HT, and DT plasmas to infer the effective ion mass, thereby closing the loop on isotope analysis and demonstrating a complementary method to typical diagnosis of the isotope ratio.…”
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268
Formation of hot spots at end-on pre-compressed isochoric fuels for fast ignition
Published 2023-01-01“…A semi-analytical model is proposed including $\alpha $ particle induced burning, hot spot collapse and other energy loss processes. …”
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269
The Statistical Properties of Solar Wind Temperature Parameters Near 1 au
Published 2018-01-01“…We present a long-duration (∼10 yr) statistical analysis of the temperatures, plasma betas, and temperature ratios for the electron, proton, and alpha-particle populations observed by the Wind spacecraft near 1 au. …”
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270
In vitro and in vivo evaluation of a tetrazine-conjugated poly-L-lysine effector molecule labeled with astatine-211
Published 2024-05-01“…Among alpha-particle emitters, 211At stands out with its 7.2 hour half-life and 100% alpha emission decay. …”
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271
Assessment of the Central Effects of Natural Uranium via Behavioural Performances and the Cerebrospinal Fluid Metabolome
Published 2016-01-01“…Natural uranium (NU), a component of the earth’s crust, is not only a heavy metal but also an alpha particle emitter, with chemical and radiological toxicity. …”
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272
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273
Lithium-doped two-dimensional perovskite scintillator for wide-range radiation detection
Published 2023“…Additionally, our Li-doped crystal shows a clear alpha particle/gamma-ray discrimination and promising thermal neutron detection through 6Li enrichment. …”
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274
Dosimetry of [<sup>212</sup>Pb]VMT01, a MC1R-Targeted Alpha Therapeutic Compound, and Effect of Free <sup>208</sup>Tl on Tissue Absorbed Doses
Published 2022-09-01“…[<sup>212</sup>Pb]VMT01 is a melanocortin 1 receptor (MC1R) targeted theranostic ligand in clinical development for alpha particle therapy for melanoma. <sup>212</sup>Pb has an elementally matched gamma-emitting isotope <sup>203</sup>Pb; thus, [<sup>203</sup>Pb]VMT01 can be used as an imaging surrogate for [<sup>212</sup>Pb]VMT01. …”
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275
Compositional Metrics of Fast and Slow Alfvénic Solar Wind Emerging from Coronal Holes and Their Boundaries
Published 2024-01-01“…We identify two FSW streams emerging from small equatorial CHs with low ion charge state ratios, low FIP bias, high Alfvénicity, and low footpoint brightness, yet anomalously low alpha particle abundance for both streams. We identify high-Alfvénicity slow solar wind emerging from the overexpanded boundary of a CH having intermediate alpha abundance, high Alfvénicity, and dips in ion charge state ratios corresponding to CH boundaries. …”
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276
Active control of Alfvén eigenmodes by external magnetic perturbations with different spatial spectra
Published 2024-01-01“…The results presented here may help to control fast-ion driven Alfvénic instabilities in future burning plasmas with a significant fusion born alpha particle population.…”
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277
A kinetic study of fusion burn waves in compressed deuterium–tritium and proton–boron plasmas
Published 2024-09-01“…This allows us to self-consistently capture the alpha particle heating and radiative losses in the expanding hot-spot and surrounding cold fuel. …”
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278
Using the photon isoeffective dose formalism to compare and combine BNCT and CIRT in a head and neck tumour
Published 2024-01-01“…The neutron capture releases two high-LET charged particles (i.e., an alpha particle and a lithium ion), losing their energy in a distance comparable to the average dimension of one cell. …”
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279
SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression.
Published 2022-11-01“…This property may result in delayed degradation of VOC Alpha particle infectivity in conditions typical of mucosal fluids of the upper respiratory tract that may be recapitulated in NCI-H1299 cells closer than in highly ACE2-expressing cell lines and models. …”
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280
Bursting core-localized ellipticity-induced Alfvén eigenmodes driven by energetic electrons during EAST ohmic discharges
Published 2024-01-01“…These novel experimental results of the wave-particle interaction between EAEs and EEs are helpful for extrapolating alpha particle physics that are characterized by small orbit width with respect to machine size in future fusion reactors.…”
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