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Development of a prototype of monitor for alpha and beta radiation in water using new silicone-based contamination-safe detectors
Published 2023-01-01“…Even an extremely low contamination of the surface can therefore destroy the detector performance, while protecting the detector with a layer of passive material will reduce the detection efficiency, in particular for alpha particles, and the passive layer can get contaminated itself, making necessary its substitution and representing an important limitation to the realization of a radioactivity monitor that should work continuously for years. …”
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342
High Performance Pd/4H-SiC Epitaxial Schottky Barrier Radiation Detectors for Harsh Environment Applications
Published 2023-07-01“…The Pd/4H-SiC SBD radiation detectors showed a very high energy resolution of 1.9% and 0.49% under self- and optimized bias, respectively, for 5486 keV alpha particles. The SBDs demonstrated a built-in voltage (<i>V<sub>bi</sub></i>) of 2.03 V and a hole diffusion length (<i>L<sub>d</sub></i>) of 30.8 µm. …”
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343
Crosstalk correction for determination of gross alpha and beta radioactivities in drinking water using a low background scintillation counter
Published 2021-09-01“…Finally, comparisons of the gross α and β radioactivities without and with the crosstalk corrections in drinking water samples were performed to verify the crosstalk correction.ResultsIt is shown that, while pulses arising from alpha particles can get into β channel, the opposite is not typically done. …”
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344
Comparing absorbed doses and radiation risk of the α-emitting bone-seekers [223Ra]RaCl2 and [224Ra]RaCl2
Published 2023-01-01“…[223Ra]RaCl2 and [224Ra]RaCl2 are bone seekers, emitting high LET, and short range (< 100 μm) alpha-particles. Both radionuclides show similar decay properties; the total alpha energies are comparable (223Ra: ≈28 MeV, 224Ra: ≈26 MeV). [224Ra]RaCl2 has been used from the mid-1940s until 1990 for treating different bone and joint diseases with activities of up to approximately 50 MBq [224Ra]RaCl2. …”
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345
A GATE simulation study for dosimetry in cancer cell and micrometastasis from the 225Ac decay chain
Published 2023-08-01“…The successive emission of four alpha particles in the 225Ac decay chain leads to highly targeted and effective cancer cell death. …”
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346
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Li–Pd–Rh-D2O electrochemistry experiments at elevated voltage
Published 2023-12-01“…Experimental results include tracks in solid-state nuclear track detectors similar in size to tracks produced by 4.7 MeV alpha particles on identical detectors exposed to radioactive Th-230; RF pulses up to 6 dB above the noise floor, which indicate that these signals were likely not background noise and not caused by known chemical reactions; and heat flux of 10 s of kJ, measured to 6σ significance, over and above input electrical energy, indicative of unknown exothermic reactions. …”
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348
Ac-EAZY! Towards GMP-Compliant Module Syntheses of <sup>225</sup>Ac-Labeled Peptides for Clinical Application
Published 2021-07-01“…Additionally, the range of alpha particles of <sup>225</sup>Ac and its daughter nuclides in tissue is much lower (47–85 μm for alpha energies E<sub>α</sub> = 5.8–8.4 MeV), which results in a very precise dose deposition within the tumor. …”
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349
Study of Monte Carlo Simulation Method for Proton Transport in NPTS Program
Published 2023-07-01“…A comparison of the stopping power of protons, deuterons and alpha particles in common materials with SRIM was carried out by the NPTS program, which proved the correctness of NPTS in calculating the stopping power of charged particles. …”
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350
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Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer
Published 2012“…Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on the nuclear capture and fission reactions that occur when non-radioactive boron-10, which is a constituent of natural elemental boron, is irradiated with low energy thermal neutrons to yield high linear energy transfer alpha particles and recoiling lithium-7 nuclei. Clinical interest in BNCT has focused primarily on the treatment of high grade gliomas, recurrent cancers of the head and neck region and either primary or metastatic melanoma. …”
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Ionizing Radiation and Estrogen Affecting Growth Factor Genes in an Experimental Breast Cancer Model
Published 2022-11-01“…The MCF-10F cell line was analyzed in different stages of transformation after being irradiated with either a single 60 cGy dose or 60/60 cGy doses of alpha particles. In the present report, the profiling of differentially expressed genes associated with growth factors was analyzed in their relationship with clinical parameters. …”
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354
A Review of Experiments Reporting Non-Conventional Phenomena in Nuclear Matter Aiming at Identifying Common Features in View of Possible Interpretation
Published 2023-07-01“…Examples of such unexpected evidences (named also non-conventional or weird) evidences are: excess heat generation, isotope production, reduction of radioactivity levels, and production of neutrons or alpha particles. These evidences are classified taking into account both the material where the evidence takes place (solutions, metals, rocks and artificial materials) and the stimulation techniques (supply of electric voltage, irradiation by photons, mechanical pressure) used to generate the evidences (which do not appear in the absence of such stimuli at an appropriate intensity). …”
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355
First preclinical evaluation of [225Ac]Ac-DOTA-JR11 and comparison with [177Lu]Lu-DOTA-JR11, alpha versus beta radionuclide therapy of NETs
Published 2023-06-01“…Furthermore, treatment with alpha emitters showed improvement of the therapeutic index of PRRT due to the high LET offered by the alpha particles compared to beta emitters. Therefore, [225Ac]Ac-DOTA-JR11 can be a potential candidate to improve the treatment of NETs (Graphical abstract). …”
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356
AlphaBet: Combination of Radium-223 and [177Lu]Lu-PSMA-I&T in men with metastatic castration-resistant prostate cancer (clinical trial protocol)
Published 2022-11-01“…The range of emitted alpha particles in soft tissue is much shorter (≤100 μm) with high linear energy transfer, likely more lethal for osseous micrometastases. …”
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357
A phase IB and randomised phase IIA trial of CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases: CARBON trial results
Published 2022-08-01“…Radium-223 (Ra223) is an alpha-emitting radiopharmaceutical that is preferentially taken up into bone at sites of increased osteoblastic activity where it emits high-energy, short-range alpha-particles that could provide a targeted anti-tumour effect on bone metastases. …”
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358
Electron Temperature Anisotropy Effects on Alpha/Proton Instability in the Solar Wind
Published 2022-09-01“…In situ recordings by the solar Wind spacecraft reveal the ubiquitousness of alpha particles, whose drift velocities to the background proton <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>v</mi><mi>α</mi></msub></semantics></math></inline-formula> are generally less than or equal to the local Alfvén velocity <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>v</mi><mi>A</mi></msub></semantics></math></inline-formula>. …”
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