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41
A Microscale Analysis of Millimeter-wave Induced Vitrified Basalt for Use in Enhanced Geothermal Energy Systems
Cyhoeddwyd 2024“...The results presented in this thesis show the creation of a non-crystalline amorphous solid that has relatively high strength values with slight evidence of micro-cracking. ...”
Cael y testun llawn
Traethawd Ymchwil -
42
Injectable sustained-release hydrogel for high-concentration antibody delivery
Cyhoeddwyd 2025“...Hydrogel encapsulation of amorphous solid antibodies has been proven to improve the stability and injectability of high-concentration antibody formulations. ...”
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Erthygl -
43
Pressure-induced amorphization and polyamorphism: Inorganic and biochemical systems
Cyhoeddwyd 2014“...Pressure-induced amorphization (PIA) is a phenomenon that involves an abrupt transition between a crystalline material and an amorphous solid through application of pressure at temperatures well below the melting point or glass transition range. ...”
Journal article -
44
In Situ Characterization of Pharmaceutical Formulations by Dynamic Nuclear Polarization Enhanced MAS NMR
Cyhoeddwyd 2018“...Here, we demonstrate that DNP polarizing agents can be added in situ during the preparation of amorphous solid dispersions (ASDs) via spray drying and hot-melt extrusion so that ASDs can be examined during drug development. ...”
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Erthygl -
45
A trade-off between solubility enhancement and physical stability upon simultaneous amorphization and nanonization of curcumin in comparison to amorphization alone
Cyhoeddwyd 2018“...While amorphization of CUR via amorphous solid dispersion (ASD) represents a well-established CUR solubility enhancement strategy, simultaneous amorphization and nanonization of CUR via amorphous CUR nanoparticles (or nano-CUR in short) have emerged only recently as the plausibly superior alternative to ASD. ...”
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Cael y testun llawn
Journal Article -
46
Amorphous drug-polyelectrolyte nanoparticle complex with controlled release functionality, enhanced amorphous stability, and its continuous production platform
Cyhoeddwyd 2020“...below 80:20) were proved to exhibit sustained CIP release compared to the native CIP and the binary CIP-DXT nanoplex in SGJ. Though the amorphous solid drug formation represents an attractive approach to enhance the solubility of poorly soluble drugs, they have a trait that the amorphous solid drug tends to become crystalline during storage due to the inherent thermodynamic instability. ...”
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Thesis-Doctor of Philosophy -
47
New Tools for Structural Biology and Biophysics: High-Throughput Fluorine Solid-State NMR and Applications to Membrane Proteins
Cyhoeddwyd 2022“...Solid-State Nuclear Magnetic Resonance (SSNMR) spectroscopy is a powerful method for characterizing the structure and dynamics of crystalline and amorphous solid compounds, materials, and biological systems. ...”
Cael y testun llawn
Cael y testun llawn
Traethawd Ymchwil -
48
Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models
Cyhoeddwyd 2019“...The purpose of this study was to assess whether 5 daily sub-cutaneous (s.c.) injections of standard flubendazole (FBZ) suspension (10mg/kg), a single s.c. injection (10mg/kg) or 5 daily repeated oral doses of FBZ amorphous solid dispersion (ASD) formulation (0.2, 1.5 or 15mg/kg) mediated macrofilaricidal efficacy against O. ochengi male worms implanted into SCID mice. ...”
Journal article -
49
A study of material condensation on liquid substrates
Cyhoeddwyd 2016“...The influence of a liquid substrate is explored by a comparative study with an amorphous solid counterpart. Simultaneous gold vapor deposition onto both silicone oil and amorphous carbon was carried out and the morphologies were found to be highly dissimilar. ...”
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Traethawd Ymchwil -
50
Wonders of glass: synthesis, elasticity and application
Cyhoeddwyd 2011“...Glass is one type of amorphous solid material which also shows property of softening progressively and continuously when heated. ...”
Cael y testun llawn
Cael y testun llawn
Inaugural Lecture -
51
Elastic, structural and optical properties of zinc borotellurite glass system doped with europium oxide co-doped silver oxide nanoparticles
Cyhoeddwyd 2022“...The XRD results show a board hump at lower diffraction angles ranging from 20° to 40° (2θ), with no sharp peaks, indicating an amorphous solid characteristic. FTIR results revealed structural units of TeO3, TeO4, BO3, and BO4. ...”
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Traethawd Ymchwil