Pathophysiological Correlation between Cigarette Smoking and Amyotrophic Lateral Sclerosis by Spiro Menounos, Philip M. Hansbro, Ashish D. Diwan, Abhirup Das

Subjects: “…amyotrophic lateral sclerosis (ALS)…”
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The role of astrocytes with genetic mutations linked to amyotrophic lateral sclerosis by D. Brash-Arias, G.E. Aranda-Abreu, F. Rojas-Durán, M.E. Hernández-Aguilar, M.R. Toledo-Cárdenas, C.A. Pérez-Estudillo, A. Ortega, L.D. Chi-Castañeda

“…Despite advances in the understanding of genetic and molecular aspects of Amyotrophic Lateral Sclerosis (ALS), a rapidly progressive and fatal neurodegenerative disease, the exact pathogenic mechanisms are still largely unknown. …”
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Misfolding at the synapse: A role in amyotrophic lateral sclerosis pathogenesis? by Jeremy S. Lum, Jeremy S. Lum, Justin J. Yerbury, Justin J. Yerbury

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The Link between VAPB Loss of Function and Amyotrophic Lateral Sclerosis by Nica Borgese, Nicola Iacomino, Sara Francesca Colombo, Francesca Navone

“…In 2004, it was discovered that a mutation (p.P56S) in the <i>VAPB</i> paralogue causes a rare form of dominantly inherited familial amyotrophic lateral sclerosis (ALS8). The mutant protein is aggregation-prone, non-functional and unstable, and its expression from a single allele appears to be insufficient to support toxic gain-of-function effects within motor neurons. …”
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Frontotemporal dementia in amyotrophic lateral sclerosis: from rarity to reality? by Marco Orsini, Ana Carolina Andorinho de Freitas Ferreira, Osvaldo J.M. Nascimento, Jano Alves de Souza, Thaís Nascimento Magalhães, Anna Carolina Damm de Assis, Larissa Kozow Westin, Bruno L. Pessoa, Acary Bulle Oliveira, Rossano Fiorelli, Marcos R.G. de Freitas, Juliana Bittencourt, Stenio Fiorelli, Maria Fernanda Freitas Ferreira Moreira, Pedro Ribeiro

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Paraneoplastic Amyotrophic Lateral Sclerosis: Case Series and Literature Review by Zhao Yang, Lu He, Manli Ren, Yizhou Lu, Huanyu Meng, Dou Yin, Sheng Chen, Qinming Zhou

Subjects: “…paraneoplastic amyotrophic lateral sclerosis…”
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Current State and Future Directions in the Diagnosis of Amyotrophic Lateral Sclerosis by Maximilian Vidovic, Lars Hendrik Müschen, Svenja Brakemeier, Gerrit Machetanz, Marcel Naumann, Sergio Castro-Gomez

Subjects: “…amyotrophic lateral sclerosis…”
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Strengths and Weaknesses of Children Witnessing Relatives with Amyotrophic Lateral Sclerosis by Ines Testoni, Lorenza Palazzo, Lucia Ronconi, Tamara Macelloni, Vincenzo Calvo

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Potential Diets to Improve Mitochondrial Activity in Amyotrophic Lateral Sclerosis by Sayuri Yoshikawa, Kurumi Taniguchi, Haruka Sawamura, Yuka Ikeda, Ai Tsuji, Satoru Matsuda

“…Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease, the pathogenesis of which is based on alternations in the mitochondria of motor neurons, causing their progressive death. …”
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MRI-Based Mapping of Cerebral Propagation in Amyotrophic Lateral Sclerosis by Hans-Peter Müller, Jan Kassubek

Subjects: “…amyotrophic lateral sclerosis…”
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Identification of Regulatory Factors and Prognostic Markers in Amyotrophic Lateral Sclerosis by Hualin Sun, Ming Li, Yanan Ji, Jianwei Zhu, Zehao Chen, Lilei Zhang, Chunyan Deng, Qiong Cheng, Wei Wang, Yuntian Shen, Dingding Shen

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle atrophy, paralysis and even death. …”
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Behavior matters--cognitive predictors of survival in amyotrophic lateral sclerosis. by William T Hu, Matthew Shelnutt, Ashley Wilson, Nicole Yarab, Crystal Kelly, Murray Grossman, David J Libon, Jaffar Khan, James J Lah, Allan I Levey, Jonathan Glass

“…It is difficult to longitudinally characterize cognitive impairment in amyotrophic lateral sclerosis (ALS) due to motor deficits, and existing instruments aren't comparable with assessments in other dementias.The ALS Brief Cognitive Assessment (ALS-BCA) was validated in 70 subjects (37 with ALS) who also underwent detailed neuropsychological analysis. …”
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Intracellular Conformation of Amyotrophic Lateral Sclerosis-Causative TDP-43 by Akira Kitamura, Sachiko Yuno, Rintaro Kawamura, Masataka Kinjo

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The preferences of people with amyotrophic lateral sclerosis on riluzole treatment in Europe by Albert C. Ludolph, Harish Grandjean, Evy Reviers, Valentina De Micheli, Cosetta Bianchi, Leonardo Cardosi, Hermann Russ, Vincenzo Silani

“…Abstract The Patient Preference Survey aims to understand unmet needs related to riluzole management in people with Amyotrophic Lateral Sclerosis (ALS) and to identify which characteristics of a new formulation could better match their preferences. …”
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Sleep disorders of insomnia type in patients with amyotrophic lateral sclerosis by G. N. Levitskiy, M. G. Poluektov

“…Objective: to evaluate the rate of sleep disorders of insomnia type among patients with amyotrophic lateral sclerosis (ALS) and to study the connection between these disorders and clinical characteristics of the disease. …”
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Dextromethorphan/quinidine for the treatment of bulbar impairment in amyotrophic lateral sclerosis by Lauren Tabor Gray, Eduardo Locatelli, Terrie Vasilopoulos, James Wymer, Emily K. Plowman

“…Abstract Objective No efficacious treatments exist to improve or prolong bulbar functions of speech and swallowing in persons with amyotrophic lateral sclerosis (pALS). This study evaluated the short‐term impact of dextromethorphan/quinidine (DMQ) treatment on speech and swallowing function in pALS. …”
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What is the right moment for noninvasive ventilation in amyotrophic lateral sclerosis? by Jovana Maskovic, Aleksandra Ilic, Vladimir Zugic, Zorica Stevic, Mihailo I. Stjepanovic

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Amyotrophic Lateral Sclerosis Genes in <i>Drosophila melanogaster</i> by Sophie Layalle, Laetitia They, Sarah Ourghani, Cédric Raoul, Laurent Soustelle

Subjects: “…amyotrophic lateral sclerosis…”
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Advances and challenges in understanding the multifaceted pathogenesis of amyotrophic lateral sclerosis by Florent Laferriere, Magdalini Polymenidou

Subjects: “…amyotrophic lateral sclerosis…”
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Efficacy of transdermal scopolamine for sialorrhea in patients with amyotrophic lateral sclerosis by Kiyomi Odachi, Yugo Narita, Yuka Machino, Tomomi Yamada, Yuki Nishimura, Yasuyuki Ota, Satoshi Tamaru, Hidekazu Tomimoto

“…Background: Sialorrhea, the excessive flow of saliva from the mouth, causes distress in about half of patients with amyotrophic lateral sclerosis (ALS). Treatments of sialorrhea in ALS include systemic anticholinergic drugs, amitriptyline, botulinum toxin injection, and salivary gland radiotherapy, although each has limitations. …”
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