Showing 401 - 420 results of 3,105 for search '"amyotrophic lateral sclerosis"', query time: 0.13s Refine Results
  1. 401

    Amyotrophic lateral sclerosis: pathogenetic mechanisms and new approaches to pharmacotherapy (literature review) by T. M. Alekseeva, T. R. Stuchevskaya, V. S. Demeshonok

    Published 2019-01-01
    “…Amyotrophic lateral sclerosis is a neurodegenerative disease, resulting in the loss of self-service and death of the middle-aged and elderly people. …”
    Get full text
    Article
  2. 402

    Interleukin-1 Antagonist Anakinra in Amyotrophic Lateral Sclerosis--A Pilot Study. by André Maier, Nikolaus Deigendesch, Kathrin Müller, Jochen H Weishaupt, Alexander Krannich, Robert Röhle, Felix Meissner, Kaaweh Molawi, Christoph Münch, Teresa Holm, Robert Meyer, Thomas Meyer, Arturo Zychlinsky

    Published 2015-01-01
    “…Preclinical studies show that blocking Interleukin-1 (IL-1) retards the progression of Amyotrophic Lateral Sclerosis (ALS). We assessed the safety of Anakinra (ANA), an IL-1 receptor antagonist, in ALS patients. …”
    Get full text
    Article
  3. 403
  4. 404

    Acute retigabine‐induced effects on myelinated motor axons in amyotrophic lateral sclerosis by Boudewijn T. H. M. Sleutjes, Diederik J. L. Stikvoort García, Maria O. Kovalchuk, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Hessel Franssen, Leonard H. van denBerg

    Published 2022-08-01
    “…Abstract Altered motor neuron excitability in patients with amyotrophic lateral sclerosis (ALS) has been suggested to be an early pathophysiological mechanism associated with motor neuron death. …”
    Get full text
    Article
  5. 405
  6. 406
  7. 407

    Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia by Francesco Antoniani, Marco Cimino, Laura Mediani, Jonathan Vinet, Enza M. Verde, Valentina Secco, Alfred Yamoah, Priyanka Tripathi, Eleonora Aronica, Maria E. Cicardi, Davide Trotti, Jared Sterneckert, Anand Goswami, Serena Carra

    Published 2023-07-01
    “…Abstract Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are two neurodegenerative disorders that share genetic causes and pathogenic mechanisms. …”
    Get full text
    Article
  8. 408

    The promise of stem cells in amyotrophic lateral sclerosis: a review of clinical trials by Muhammad Usman Khalid, Taleaa Masroor

    Published 2023-01-01
    “…Keywords: Amyotrophic Lateral Sclerosis. Biocompatible Materials, Neural, Stem Cells …”
    Get full text
    Article
  9. 409
  10. 410
  11. 411
  12. 412

    How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients by Jesus Sancho, Santos Ferrer

    Published 2023-03-01
    “…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. …”
    Get full text
    Article
  13. 413
  14. 414
  15. 415

    SOMAscan Proteomics Identifies Novel Plasma Proteins in Amyotrophic Lateral Sclerosis Patients by Elena Berrone, Giovanna Chiorino, Francesca Guana, Valerio Benedetti, Claudia Palmitessa, Marina Gallo, Andrea Calvo, Federico Casale, Umberto Manera, Alessandra Favole, Paola Crociara, Camilla Testori, Valerio Carta, Carlotta Tessarolo, Antonio D’Angelo, Giovanni De Marco, Maria Caramelli, Adriano Chiò, Cristina Casalone, Cristiano Corona

    Published 2023-01-01
    “…Amyotrophic lateral sclerosis (ALS) is a complex disease characterized by the interplay of genetic and environmental factors for which, despite decades of intense research, diagnosis remains rather delayed, and most therapeutic options fail. …”
    Get full text
    Article
  16. 416
  17. 417
  18. 418
  19. 419

    Protein kinetics of superoxide dismutase‐1 in familial and sporadic amyotrophic lateral sclerosis by Cindy V. Ly, Margaret D. Ireland, Wade K. Self, James Bollinger, Jennifer Jockel‐Balsarotti, Hillary Herzog, Peggy Allred, Leah Miller, Michael Doyle, Isabel Anez‐Bruzual, Bhavesh Trikamji, Ted Hyman, Tyler Kung, Katherine Nicholson, Robert C. Bucelli, Bruce W. Patterson, Randall J. Bateman, Timothy M. Miller

    Published 2023-06-01
    “…Abstract Objective Accumulation of misfolded superoxide dismutase‐1 (SOD1) is a pathological hallmark of SOD1‐related amyotrophic lateral sclerosis (ALS) and is observed in sporadic ALS where its role in pathogenesis is controversial. …”
    Get full text
    Article
  20. 420