Role of FAAH-like anandamide transporter in anandamide inactivation. by Kwannok Leung, Matthew W Elmes, Sherrye T Glaser, Dale G Deutsch, Martin Kaczocha

“…The endocannabinoid system modulates numerous physiological processes including nociception and reproduction. Anandamide (AEA) is an endocannabinoid that is inactivated by cellular uptake followed by intracellular hydrolysis by fatty acid amide hydrolase (FAAH). …”
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The endocannabinoid anandamide is an airway relaxant in health and disease by Annika Simon, Thomas von Einem, Alexander Seidinger, Michaela Matthey, Laura Bindila, Daniela Wenzel

“…Here, the authors identify the endocannabinoid anandamide (AEA) as an airway relaxant under physiological and pathophysiological conditions that can be locally applied to the lung as an aerosol in mice.…”
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Altered Anandamide Degradation in Attention Deficit Hyperactivity Disorder by J Gordon Millichap

Subjects: “…anandamide…”
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High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. by Orison O Woolcott, Joyce M Richey, Morvarid Kabir, Robert H Chow, Malini S Iyer, Erlinda L Kirkman, Darko Stefanovski, Maya Lottati, Stella P Kim, L Nicole Harrison, Viorica Ionut, Dan Zheng, Isabel R Hsu, Karyn J Catalano, Jenny D Chiu, Heather Bradshaw, Qiang Wu, Cathryn M Kolka, Richard N Bergman

“…BACKGROUND:Obesity has been associated with elevated plasma anandamide levels. In addition, anandamide has been shown to stimulate insulin secretion in vitro, suggesting that anandamide might be linked to hyperinsulinemia. …”
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The correlation of anandamide with gonadotrophin and sex steroid hormones during the menstrual cycle by Na Cui, Luning Wang, Wei Wang, Jie Zhang, Yueming Xu, Lei Jiang, Guimin Hao

Subjects: “…Anandamide…”
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The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and Differentiation. by Marie Smith, Richard Wilson, Sally O'Brien, Cristina Tufarelli, Susan I Anderson, Saoirse Elizabeth O'Sullivan

“…Human osteoblasts were treated from seeding with increasing concentrations of anandamide or 2-arachidonoylglycerol for between 1 and 21 days. …”
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The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. by Eric Di Pasquale, Henri Chahinian, Patrick Sanchez, Jacques Fantini

“…Anandamide is a lipid neurotransmitter which belongs to a class of molecules termed the endocannabinoids involved in multiple physiological functions. …”
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Effects of intracerebroventricular anandamide administration on feed intake and milk yield of dairy cows by Björn Kuhla, Isabel van Ackern

“…Among the endocannabinoids, N-arachidonylethanolamide (AEA; anandamide) plays a key role in regulating energy homeostasis and energy intake. …”
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Direct Anandamide Activation of TRPV1 Produces Divergent Calcium and Current Responses by Axel J. Fenwick, Daniel K. Fowler, Shaw-Wen Wu, Forrest J. Shaffer, Jonathan E. M. Lindberg, Dallas C. Kinch, James H. Peters

“…The endogenous membrane lipid anandamide (AEA) is a putative TRPV1 agonist in the brain, yet the extent to which AEA activation of TRPV1 has a neurophysiological consequence is not well established. …”
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Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats by Roxana N. Peroni, Tamara Abramoff, Isabel Neuman, Ernesto J. Podestá, Edda Adler-Graschinsky

“…Oral treatment with phytoestrogens also restored the vascular effects of anandamide as well as the mesenteric content of calcitonin gene-related peptide (CGRP) that were reduced after ovariectomy. …”
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Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. by María Gracia Gervasi, Claudia Osycka-Salut, Julieta Caballero, Mónica Vazquez-Levin, Elba Pereyra, Silvia Billi, Ana Franchi, Silvina Perez-Martinez

“…Anandamide (AEA), a major endocannabinoid, binds to cannabinoid and vanilloid receptors (CB1, CB2 and TRPV1) and affects many reproductive functions. …”
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Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder by Isabel Baenas, Neus Solé-Morata, Roser Granero, Fernando Fernández-Aranda, Mitona Pujadas, Bernat Mora-Maltas, Ignacio Lucas, Mónica Gómez-Peña, Laura Moragas, Amparo del Pino-Gutiérrez, Javier Tapia, Rafael de la Torre, Marc N. Potenza, Susana Jiménez-Murcia

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The Influence of Anandamide on the Anterior Pituitary Hormone Secretion in Ewes—Ex Vivo Study by Dorota Tomaszewska-Zaremba, Karolina Wojtulewicz, Kamila Paczesna, Monika Tomczyk, Katarzyna Biernacka, Joanna Bochenek, Andrzej Przemysław Herman

Subjects: “…anandamide…”
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Inhibition by Anandamide of 6-Hydroxydopamine-Induced Cell Death in PC12 Cells by Katarzyna Mnich, David P. Finn, Eilis Dowd, Adrienne M. Gorman

“…Together, these data demonstrate antiapoptotic effects of anandamide and also suggest a role for activation of PI3K and inhibition of JNK signalling in anandamide-mediated protection against 6-OHDA.…”
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Anandamide Effects in a Streptozotocin-Induced Alzheimer’s Disease-Like Sporadic Dementia in Rats by Daniel Moreira-Silva, Daniel C. Carrettiero, Adriele S. A. Oliveira, Samanta Rodrigues, Joyce dos Santos-Lopes, Paula M. Canas, Rodrigo A. Cunha, Rodrigo A. Cunha, Maria C. Almeida, Tatiana L. Ferreira

“…Thus, the aim of this study was to investigate the preventive effects of anandamide (N-arachidonoylethanolamine, AEA) on multiple cognitive deficits and on the levels of synaptic proteins (syntaxin 1, synaptophysin and synaptosomal-associated protein, SNAP-25), cannabinoid receptor type 1 (CB1) and molecules related to p-tau degradation machinery (heat shock protein 70, HSP70), and Bcl2-associated athanogene (BAG2) in an AD-like sporadic dementia model in rats using intracerebroventricular (icv) injection of streptozotocin (STZ). …”
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Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. by Martin Kaczocha, Mario J Rebecchi, Brian P Ralph, Yu-Han Gary Teng, William T Berger, William Galbavy, Matthew W Elmes, Sherrye T Glaser, Liqun Wang, Robert C Rizzo, Dale G Deutsch, Iwao Ojima

“…The endocannabinoid anandamide (AEA) is an antinociceptive lipid that is inactivated through cellular uptake and subsequent catabolism by fatty acid amide hydrolase (FAAH). …”
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Anandamide Alters Barrier Integrity of Bovine Vascular Endothelial Cells during Endotoxin Challenge by Carsten C. F. Walker, Lorraine M. Sordillo, G. Andres Contreras

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A zebrafish HCT116 xenograft model to predict anandamide outcomes on colorectal cancer by Francesca Maradonna, Camilla M. Fontana, Fiorenza Sella, Christian Giommi, Nicola Facchinello, Chiara Rampazzo, Micol Caichiolo, Seyed Hossein Hoseinifar, Luisa Dalla Valle, Hien Van Doan, Oliana Carnevali

“…Several in vitro studies reported anandamide’s (AEA) ability to block cancer cell proliferation and migration, but evidence from in vivo studies is still lacking. …”
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The Role of the Endocannabinoids 2-AG and Anandamide in Clinical Symptoms and Treatment Outcome in Veterans with PTSD by N.A. Leen, A.D. de Weijer, S.J.H. van Rooij, M. Kennis, J.M.P. Baas, E. Geuze

“…The present study examined whether the endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2-AG) are associated with post-treatment symptom reduction. …”
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Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamate by Finazzi-Agrò Alessandro, Bari Monica, Battista Natalia, Maccarrone Mauro

“…<p>Abstract</p> <p>Anandamide (<it>N</it>-arachidonoylethanolamine, AEA) belongs to an emerging class of endogenous lipids, called "endocannabinoids". …”
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