Decursinol-mediated antinociception and anti-allodynia in acute and neuropathic pain models in male mice: Tolerance and receptor profiling by LaTaijah C. Crawford, LaTaijah C. Crawford, Sangyub Kim, Deepkamal Karelia, Diana E. Sepulveda, Daniel J. Morgan, Junxuan Lü, Junxuan Lü, Angela N. Henderson-Redmond

“…Korean scientists have shown that oral administration of Angelica gigas Nakai (AGN) root alcoholic extract and the metabolite of its pyranocoumarins, decursinol, have antinociceptive properties across various thermal and acute inflammatory pain models. …”
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Identification of Anti-Inflammatory Compounds from <i>Peucedanum praeruptorum</i> Roots by Using Nitric Oxide-Producing Rat Hepatocytes Stimulated by Interleukin 1β by Hiromu Ozaki, Yuto Nishidono, Airi Fujii, Tetsuya Okuyama, Kaito Nakamura, Takanori Maesako, Saki Shirako, Richi Nakatake, Ken Tanaka, Yukinobu Ikeya, Mikio Nishizawa

“…The roots of <i>Peucedanum praeruptorum</i> Dunn and <i>Angelica decursiva</i> Franchet et Savatier are designated <i>Zenko</i>, which is a crude drug defined by the Japanese Pharmacopoeia. …”
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Morphological, molecular, and biological characterization of bulb rot pathogens in stored Lanzhou lily and the in vitro antifungal efficacy of three plant essential oils by Chaoqun Liu, Yinquan Wang, Yinquan Wang, Ling Jin, Ling Jin, Yan Wang, Dongling Liu

“…Among the three essential oils tested, cinnamon essential oil displayed superior antifungal efficacy against F. oxysporum, whereas angelica essential oil and tea tree essential oil also exhibited moderate inhibitory effects against this pathogen. …”
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An Overview of Herbal Nutraceuticals, Their Extraction, Formulation, Therapeutic Effects and Potential Toxicity by Vaishnavi Bommakanti, Amruthamol Puthenparambil Ajikumar, Chelssa Maria Sivi, Geethika Prakash, Anjaly Shanker Mundanat, Faraz Ahmad, Shafiul Haque, Miguel Angel Prieto, Sandeep Singh Rana

“…The current review enlists various traditional as well as unexplored herbs including angelica, burnet, caraway, laurel, parsley, yarrow, and zedoary, which are rich sources of bioactive components, such as aloesin, angelicin, trans-anethole, and cholesteric-7-en-3β-ol. …”
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Pharmacokinetics and Brain Distribution of the Active Components of DA-9805, Saikosaponin A, Paeonol, and Imperatorin in Rats by Mi Hye Kwon, Jin Seok Jeong, Jayoung Ryu, Young Woong Cho, Hee Eun Kang

“…DA-9805 is a botanical anti-Parkinson&rsquo;s drug candidate formulated from ethanol extracts of the root of Bupleurum falcatum, the root cortex of Paeonia suffruticosa, and the root of Angelica dahurica. The pharmacokinetics (PKs) and brain distribution of active/representative ingredients of DA-9805, Saikosaponin a (SSa; 1.1&ndash;4.6 mg/kg), Paeonol (PA; 14.8&ndash;59.2 mg/kg), and Imperatorin (IMP; 1.4&ndash;11.5 mg/kg) were evaluated following the intravenous or oral administration of each pure component and the equivalent dose of DA-9805 in rats. …”
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Astragalus and its formulas as a therapeutic option for fibrotic diseases: Pharmacology and mechanisms by Yi Zhu, Yilu Chai, Guojin Xiao, Yufei Liu, Xiaohong Xie, Wei Xiao, Pengcheng Zhou, Wei Ma, Chuantao Zhang, Liuying Li, Liuying Li

“…We also review formulas that contain Astragalus with anti-fibrotic effects, in which Astragalus and Salvia miltiorrhiza Bunge, Astragalus and Angelica sinensis (Oliv.) Diels are the most commonly used combinations. …”
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Traditional Chinese medicine Zhusha Anshen Wan: protective effects on liver, kidney, and intestine of the individual drugs using 1H NMR metabolomics by Dalu Wang, Chong Yu, Beixing Liu, Haifeng Wang

“…The metabolic profiles of the urine and serum of the rats in the CGU (treated with cinnabar and Glycyrrhiza uralensis Fisch) and CCC (treated with cinnabar and Coptis chinensis French) groups were remarkably similar to those of the control group, while those of the CRG (treated with cinnabar and Rehmannia glutinosa Libosch) and CAS (treated with cinnabar and Angelica sinensis) groups were close to those of the cinnabar group. …”
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Derma-Hc, a New Developed Herbal Formula, Ameliorates Cutaneous Lichenification in Atopic Dermatitis by Yeon Kyung Nam, Mi Hye Kim, In Jin Ha, Woong Mo Yang

“…Derma-Hc is composed of five natural herbs with anti-AD effects, such as <i>Astragalus membranaceus</i> BUNGE, <i>Schizonepeta tenuifolia</i> Briq., <i>Cryptotympana pustulata</i> Fabr., <i>Angelica sinensis</i> Diels, <i>Arctium lappa</i> L. …”
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Polycystic Ovary Syndrome: A Disorder of Reproductive Age, Its Pathogenesis, and a Discussion on the Emerging Role of Herbal Remedies by Ling-Hui Zeng, Saba Rana, Liaqat Hussain, Muhammad Asif, Malik Hassan Mehmood, Imran Imran, Anam Younas, Amina Mahdy, Fakhria A. Al-Joufi, Shaymaa Najm Abed

“…[Ranunculaceae], and Angelica sinensis (Oliv.) Diels [Apiaceae] are effective and harmless. …”
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Low-Frequency Imaging of Fields at High Galactic Latitude with the Murchison Widefield Array 32 Element Prototype by Williams, Christopher Leigh, Hewitt, Jacqueline N, Levine, Alan M

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Traditional Chinese Medicine Shi-Bi-Man ameliorates psoriasis via inhibiting IL-23/Th17 axis and CXCL16-mediated endothelial activation by Chenyang Zhang, Xinran Cao, Lixin Zhao, Zitong Ni, Haojie Du, Jiao Qu, Jianxia Zhu, Haiyan Sun, Yang Sun, Zijun Ouyang

“…Shi-Bi-Man (SBM) is a safe herbal supplement sourced from various natural plants, including ginseng, angelica sinensis, polygonum multiflorum, and aloe vera. …”
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Effects of Danggui Buxue decoction on host gut microbiota and metabolism in GK rats with type 2 diabetes by Wen-kai Wang, Wen-kai Wang, Lu Fan, Fan Ge, Zihang Li, Jingtian Zhu, Kai Yin, Jinyan Xia, Mei Xue

“…Danggui Buxue decoction (DBD), a classical Chinese herbal formula composed of Astragalus membranaceus (Huangqi) and Angelica sinensis (Danggui), has been widely used in the clinical treatment of diabetes and its complications. …”
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A comprehensive review of the anticancer effects of decursin by Yueming Chu, Yueming Chu, Qiang Yuan, Qiang Yuan, Hangyu Jiang, Hangyu Jiang, Liang Wu, Yutao Xie, Yutao Xie, Xiaofen Zhang, Lin Li, Lin Li

“…Decursin, a coumarin analog mainly derived from the roots of the medicinal plant Angelica sinensis, has a wide range of biological activities, including anti-inflammatory, antioxidant, neuroprotective, and especially anticancer activities. …”
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Adherence to Subcutaneous Anti-Tumour Necrosis Factor Treatment in a Cohort of Patients with Rheumatoid Arthritis Before and After the Implementation of a Comprehensive Care Model by Santos-Moreno P, Sánchez-Vanegas G, Monterrosa-Blanco A, Rodríguez-Vargas GS, Rivero M, Rodriguez P, Calixto OJ, Rojas-Villarraga A, Castro CA

“…Pedro Santos-Moreno,1 Guillermo Sánchez-Vanegas,2 Angélica Monterrosa-Blanco,3 Gabriel-Santiago Rodríguez-Vargas,1 Manuel Rivero,1 Pedro Rodriguez,1 Omar-Javier Calixto,4 Adriana Rojas-Villarraga,5 Carlos Alberto Castro3 1Rheumatology Department, Biomab IPS, Bogotá, Colombia; 2Scientific Direction Department, Hospital Universitario Mayor Mederi, Universidad del Rosario, Bogotá, Colombia; 3Research and Health Education Department, Comprehensive Solutions for Health Research and Education-SIIES, Bogotá, Colombia; 4Rheumatology and Immunology Department, Hospital Militar Central, Bogotá, Colombia; 5Research Institute, Fundación Universitaria de Ciencias de la Salud–FUCS, Bogotá, ColombiaCorrespondence: Pedro Santos-Moreno, Rheumatology Department, Biomab IPS, Calle 48 &num; 13-86, Bogotá, Colombia, Tel +57 320 8094232, Email pedrosantosmoreno@hotmail.comPurpose: To assess, in a cohort of patients with rheumatoid arthritis (RA) treated with subcutaneous antitumor necrosis factor drugs (anti-TNFs), the levels of treatment adherence before and after implementing a comprehensive care model (CCM).Patients and Methods: An observational study including RA patients under treatment with subcutaneous anti-TNFs (adalimumab, etanercept, and golimumab) selected at convenience was performed; a sample size of 125 patients was calculated. …”
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Breakfast Consumption Habit and Its Nutritional Contribution in Latin America: Results from the ELANS Study by Mauro Fisberg, Irina Kovalskys, Agatha Nogueira Previdelli, Jaqueline Lopes Pereira, Ioná Zalcman Zimberg, Regina Fisberg, Gerson Ferrari, Viviana Guajardo, the ELANS Study Group

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Comparative efficacy of Jaungo, a traditional herbal ointment, and a water-in-oil type non-steroidal moisturizer for radiation-induced dermatitis in patients with breast cancer: a... by Eun Hye Kim, Su Bin Park, Hayun Jin, Weon Kuu Chung, Seong Woo Yoon

“…Therefore, this study aimed to evaluate the comparative efficacy and safety of Jaungo (mainly composed of Lithospermum erythrorhizon Siebold &amp; Zucc. and Angelica sinensis (Oliv.) Diel) and the water-in-oil-type non-steroidal moisturizer for the prevention of RID in patients with breast cancer (BC).Methods: This is a prospective, single-blind, pilot randomized controlled trial. …”
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Climate-induced changes in essential oil production and terpene composition in alpine aromatic plants by Pradeep Dobhal, Vijay Kant Purohit, Sudeep Chandra, Sandeep Rawat, P. Prasad, Ujjwal Bhandari, Vijay Laxmi Trivedi, M.C. Nautiyal

“…This study examines the impacts of elevated CO2 (eCO2) and combined effects of elevated CO2 and temperature (eCO2+T) on two alpine aromatic herbs, namely Angelica glauca and Nardostachys jatamansi. These species were raised in open-top chambers (OTCs) and treated with elevated CO2 (600 ppm) and temperature (+2.0 °C from control) during 2018 to 2020. …”
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Could Natural Products Help in the Control of Obesity? Current Insights and Future Perspectives by Jiwon Park, Fahrul Nurkolis, Hyunji Won, Jiye Yang, Dayeon Oh, Hyunkyung Jo, Jinwon Choi, Sanghyun Chung, Rudy Kurniawan, Bonglee Kim

“…Several clinical studies reported that natural products showed antiobesity effects, including <i>Coffea arabica</i> (coffee), <i>Camellia sinensis</i> (green tea), <i>Caulerpa racemosa</i> (green algae), <i>Allium sativum</i> (garlic), combined <i>Ephedra intermedia</i> Schrenk, <i>Thea sinensis</i> L., and <i>Atractylodes lancea</i> DC extract (known as Gambisan), <i>Ephedra sinica</i> Stapf, Angelica Gigantis Radix, Atractylodis Rhizoma Alba, <i>Coicis semen</i>, <i>Cinnamomi cortex</i>, <i>Paeoniae radix</i> alba, and <i>Glycyrrhiza uralensis</i> (known as Euiiyin-tang formula). …”
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How parents’ feeding styles, attitudes, and multifactorial aspects are associated with feeding difficulties in children by Evelin Czarny Hasbani, Paula Victória Félix, Patricia Kawai Sauan, Priscila Maximino, Rachel Helena Vieira Machado, Gerson Ferrari, Mauro Fisberg

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An extract from the frass of swallowtail butterfly (Papilio machaon) larvae inhibits HCT116 colon cancer cell proliferation but not other cancer cell types by Miho Nakano, Takuma Sakamoto, Yoshikazu Kitano, Hidemasa Bono, Richard J. Simpson, Hiroko Tabunoki

“…In this study, we extracted the components of the frass of Papilio machaon larvae reared on Angelica keiskei, Oenanthe javanica or Foeniculum vulgare and examined the biological activity of each component. …”
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