Implication of CXCR2-Src axis in the angiogenic and osteogenic effects of FP-TEB by Sihao He, Tianyong Hou, Jiangling Zhou, Bo Yu, Juan Cai, Fei Luo, Jianzhong Xu, Junchao Xing

“…In conclusion, FP-TEBs promoted EC migration, angiogenesis, and osteogenesis via the CXCR2-Src-Map4k4-p38 MAPK axis.…”
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C3a-C3aR signaling promotes breast cancer lung metastasis via modulating carcinoma associated fibroblasts by Chi Shu, Haoran Zha, Haixia Long, Xinxin Wang, Fei Yang, Jianbao Gao, Chunyan Hu, Li Zhou, Bo Guo, Bo Zhu

“…Abstract Background Mounting evidence suggests that complement components promote tumor progression via modulating immune suppression, angiogenesis, or tumor cell proliferation. However, the role of C3a-C3aR signaling in regulating lung metastasis of breast cancer remains unknown. …”
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Advancements in diabetic foot ulcer research: Focus on mesenchymal stem cells and their exosomes by ShuHui Wu, ZhongSheng Zhou, Yang Li, Jinlan Jiang

“…Presently, MSCs have been validated as a highly promising cellular therapeutic approach for DFU, capable of effectuating cellular repair, epithelialization, granulation tissue formation, and neovascularization by means of targeted differentiation, angiogenesis promotion, immunomodulation, and paracrine activities, thereby fostering wound healing. …”
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Frontier Review of the Molecular Mechanisms and Current Approaches of Stem Cell-Derived Exosomes by Liang-Yun Chen, Ting-Wan Kao, Chang-Cyuan Chen, Noreen Niaz, Hsin-Lun Lee, Yu-Hsin Chen, Chia-Chun Kuo, Yao-An Shen

“…They are shown to possess the capacity to affect cell proliferation, migration, anti-apoptosis, anti-scarring, and angiogenesis, via the action of transporting molecular components. …”
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Cytotoxicity Effectiveness of Biosynthesized Silver Nanoparticles on Breast Cancer T47D Cell Line, Using Macro Algae Laurencia caspica Extract by Ali Salehzadeh, Ataollah Sadat Shandiz, Akram Sadat Naeemi

“…Introduction: Over the past years, silver nanoparticles (AgNPs) due to their anti-angiogenesis, anti-bacterial, and anti-cancer activity have attracted researchers’ interests. …”
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Tumor Necrosis Factor-α (TNFα) Stimulates Triple-Negative Breast Cancer Stem Cells to Promote Intratumoral Invasion and Neovasculogenesis in the Liver of a Xenograft Model by Harini Narasimhan, Francesca Ferraro, Andreas Bleilevens, Ralf Weiskirchen, Elmar Stickeler, Jochen Maurer

“…However, the causes and effects of tumor angiogenesis are still poorly understood. In this study, we demonstrate TNFα effects on primary triple-negative breast cancer stem cells (BCSCs). …”
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Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment by Franck Verrecchia, Françoise Rédini

“…TGF-β can thus exert its protumorigenic function in primary bone tumors by promoting angiogenesis, bone remodeling and cell migration, and by inhibiting immunosurveillance. …”
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Metastatic rectal cancer to papillary thyroid carcinoma: a case report and review of literature by Min Luo, Yu Huang, Yongqiang Li, Yumei Zhang

“…The patient received levothyroxine supplementation therapy and palliative chemotherapy with irinotecan and anti-angiogenesis for the metastatic rectal adenocarcinoma. …”
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Discovery of Notch Pathway-Related Genes for Predicting Prognosis and Tumor Microenvironment Status in Bladder Cancer by Xianchao Sun, Shiyong Xin, Weiyi Li, Ying Zhang, Lin Ye

“…An abnormally activated Notch signaling pathway contributes to almost all of the key features of cancer, including tumor angiogenesis, stemness, and epithelial-mesenchymal transition. …”
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The healing effects of herbal preparations from Sambucus ebulus and Urtica dioica in full-thickness wound models by Esmaeil Babaei, Mohammad Hossein Asghari, Fatemeh Mehdikhani, Milad Moloudizargari, Emad Ghobadi, Seyedeh Rokhsane Hosseini Pouya

“…Several factors including the number of fibroblasts, new vessel formation (angiogenesis), thickness of the granulomatous tissues (GT), and the overlying epithelium were analyzed. …”
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2-Methoxyestradiol Exhibits a Biphasic Effect on VEGF-A in Tumor Cells and Upregulation Is Mediated Through ER-α: A Possible Signaling Pathway Associated with the Impact of 2-ME2 o... by Samarendra N. Banerjee, Krishanu Sengupta, Snigdha Banerjee, Neela K. Saxena, Sushanta K. Banerjee

“…2-Methoxyestradiol (2-ME2) was reported to elicit both stimulation and inhibition of tumor angiogenesis and growth depending on the dosage used. …”
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Subclassification of patients with acute myelogenous leukemia based on chemokine responsiveness and constitutive chemokine release by their leukemic cells by Øystein Bruserud, Anita Ryningen, Astrid Marta Olsnes, Laila Stordrange, Anne Margrete Øyan, Karl Henning Kalland, Bjørn Tore Gjertsen

“…Background and Objectives Chemokines are soluble mediators involved in angiogenesis, cellular growth control and immunomodulation. …”
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Anticancer properties and mechanisms of botanical derivatives by Sudharma Banerjee, Stella Nau, Steven N. Hochwald, Huisheng Xie, Jianliang Zhang

“…Signal cascades that are responsible for proliferation, cell cycle arrest, apoptosis, and angiogenesis are implicated in the actions and effects of medicinal plants and their derivatives. …”
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Clinical effects and mechanisms of a Chinese patent medicine, Tongxinluo capsule, as an adjuvant treatment in coronary heart disease by Jing Wang, Tian Li Li, Pei Fen Chang, Yu Qian Gao, Jia Sai Fan, Chen Hao Zhang, Hai Yan Zhu

“…In this review, the pharmacological properties of TXL include regulation of blood lipids, improvement of endothelial function, anti-inflammatory, antioxidant, inhibition of apoptosis and regulation of autophagy, anti-fibrosis, promotion of angiogenesis, and modulation of exosome communication. …”
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Lymphangiogenic responses of lymphatic endothelial cells to steady direct-current electric fields by Linbo Guan, Ping Fan, Yufeng Wang, Xinghui Liu, Rui Liu, Wandi Ma, Huai Bai

“…Steady direct-current electric fields (DC EFs) induce vascular endothelial behaviors related to angiogenesis have been observed. This study investigated the effects of DC EFs on the lymphangiogenic response of lymphatic endothelial cells (LECs). …”
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Neutrophil granulocytes: participation in homeostatic and reparative processes. Part I by I. I. Dolgushin, E. A. Mezentseva

“…Neutrophils participate in destruction of endometrial tissues during desquamation phase as well as subsequent repair and physiological angiogenesis during proliferative phase of the menstrual cycle; promote wall rupture of the preovulatory ovarian follicle and oocyte exit; contribute to degradation and resorption of the corpus luteum in pregnancy failure; play an important physiological role in vascular remodeling in pregnant uterus and developing maternal immune tolerance to semi-allogeneic fetus. …”
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Hydrogel-Based Scaffolds in Oral Tissue Engineering by Alfredo Ayala-Ham, Alfredo Ayala-Ham, Jorge López-Gutierrez, Mercedes Bermúdez, Maribel Aguilar-Medina, Juan Ignacio Sarmiento-Sánchez, César López-Camarillo, Guzman Sanchez-Schmitz, Rosalio Ramos-Payan

“…HG can induce changes in cellular processes such as chemotaxis, proliferation, angiogenesis, biomineralization, and expression of specific tissue biomarkers, enhancing the regeneration process. …”
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Anti-tumor therapy with macroencapsulated endostatin producer cells by Balduino Keli N, Chura-Chambi Rosa M, da Costa Patrícia LN, Malavasi Natália V, Chammas Roger, Rodrigues Danielle B, Morganti Ligia

“…Endostatin is a potent inhibitor of angiogenesis and tumor growth. Continuous delivery of endostatin improves the efficacy and potency of the antitumoral therapy. …”
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Myocardium-derived conditioned medium improves left ventricular function in rodent acute myocardial infarction by Yeh Kuo-Ho, Chua Sarah, Chang Li-Teh, Tsai Tzu-Hsien, Lin Yu-Chun, Sun Cheuk-Kwan, Kao Ying-Hsien, Leu Steve, Wu Chiung-Jen, Fu Morgan, Yip Hon-Kan

“…</p> <p>Conclusion</p> <p>MDCM therapy reduced cardiac fibrosis and oxidative stress, enhanced angiogenesis, and preserved 90-day LV function in a rat AMI model.…”
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Apigenin: A Bioflavonoid with a Promising Role in Disease Prevention and Treatment by Khaled S. Allemailem, Ahmad Almatroudi, Hajed Obaid A. Alharbi, Naif AlSuhaymi, Mahdi H. Alsugoor, Fahad M. Aldakheel, Amjad Ali Khan, Arshad Husain Rahmani

“…Multiple studies have reported that this compound is capable of suppressing various types of cancer through the induction of apoptosis and cell-cycle arrest, suppressing cell migration and invasion, reduction of inflammation, and inhibiting angiogenesis. When used in combination with other drugs, apigenin increases their efficacy, reduces the risk of side effects, and improves the response to chemotherapy. …”
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