Angiogenesis Inhibitors and Immunomodulation in Renal Cell Cancers: The Past, Present, and Future by Lawrence Kasherman, Derrick Ho Wai Siu, Rachel Woodford, Carole A. Harris

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Activity of Angiogenesis Inhibitors in Metastatic Epithelioid Hemangioendothelioma: A Case Report by Sumit Gaur, Alireza Torabi, Thomas J O'Neill

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Challenges in developing a validated biomarker for angiogenesis inhibitors: the motesanib experience. by Michael B Bass, Bin Yao, Yong-Jiang Hei, Yining Ye, Gerard J Davis, Michael T Davis, Barbara A Kaesdorf, Sabrina S Chan, Scott D Patterson

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Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish. by Antonio Mauro, Robin Ng, Jamie Yuanjun Li, Rui Guan, Youdong Wang, Krishna Kumar Singh, Xiao-Yan Wen

“…A Tg(kdrl:EGFP) line, marking endothelial cell cytoplasm, was used in this work to help develop protocols and functional algorithms for the system, with the intent of screening for angiogenesis inhibitors. Indirubin 3' Monoxime (I3M), a known angiogenesis inhibitor, was used at various concentrations to validate the protocols. …”
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Brain-specific angiogenesis inhibitor 1 is expressed in the Myo/Nog cell lineage. by Jacquelyn Gerhart, Jessica Bowers, Lindsay Gugerty, Colby Gerhart, Mark Martin, Fathma Abdalla, Arturo Bravo-Nuevo, Jonathan Tabb Sullivan, Rebecca Rimkunas, Amie Albertus, Lou Casta, Lori Getts, Robert Getts, Mindy George-Weinstein

“…G8 mAb binding to the clone expressing brain-specific angiogenesis inhibitor 1 (BAI1) was detected by flow cytometry, re-verified by sequencing and validated by transfection with the plasmid construct for BAI1. …”
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Analyzing the Electrochemical Interaction of the Angiogenesis Inhibitor Batimastat by Surface-Enhanced Raman Spectroscopy by Ewa Pięta, Czesława Paluszkiewicz, Wojciech M. Kwiatek, María Rosa López-Ramírez

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The efficacy and safety of angiogenesis inhibitors for recurrent ovarian cancer: a meta‑analysis by Chunmei Zhang, Wancheng Zhao

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Influence of Levamisole and Other Angiogenesis Inhibitors on Angiogenesis and Endothelial Cell Morphology in Vitro by Gunnar Houen, Line S. Larsen, Christine D. Bendiksen, Anne-Marie Engel, Tina Friis

“…A humanized antibody to VEGF is one of a few angiogenesis inhibitors used clinically for treatment of cancer. …”
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Study of endostatin, tumstatin and PEDF, the natural angiogenesis inhibitors, potential in avasculargenic therapy by V. G. Likhvantseva, E. V. Arutyunyan, A. I. Miroshnikov, A. Yu. Salihov, O. V. Belous, K. D. Kurtshalidze, R. S. Esipov, K. A. Bejrahova, V. N. Stepanenko

“…Purpose: To evaluate the potential of endostatin, tumstatin and PEDF in avasculargenic therapy.Methods: The avasculargenic potential of the natural angiogenesis inhibitors was explored on the model of alkaline burn, attended with angiogenesis of cornea. …”
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A Novel Angiogenesis Inhibitor Bevacizumab Induces Apoptosis in the Rat Endometriosis Model by Soysal D., Kızıldağ S., Saatlı B., Posacı C., Soysal S., Koyuncuoğlu M., Doğan Ö. E.

“…This study suggests that a novel angiogenesis inhibitor, anti-VEGF antibody bevacizumab is as effective as GnRH agonist in the regression of the endometriotic lesions in rat endometriosis model. …”
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IMMUNOREGULATORY PROPERTIES OF THROMBOSPONDIN-1, A EXTRACELLULAR MATRIX COMPONENT AND ANGIOGENESIS INHIBITOR by S. A. Kuznetsova, A. V. Krylov, E. P. Kiseleva

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Angiogenesis Inhibitors for Head and Neck Squamous Cell Carcinoma Treatment: Is There Still Hope? by Aini Hyytiäinen, Aini Hyytiäinen, Wafa Wahbi, Wafa Wahbi, Otto Väyrynen, Kauko Saarilahti, Peeter Karihtala, Tuula Salo, Tuula Salo, Tuula Salo, Tuula Salo, Tuula Salo, Ahmed Al-Samadi, Ahmed Al-Samadi

“…Among 12 angiogenesis inhibitors, bevacizumab was the most studied drug, included in 13 trials. …”
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Current Status of Angiogenesis Inhibitors as Second-Line Treatment for Unresectable Colorectal Cancer by Satoshi Otsu, Shuichi Hironaka

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Correction: challenges in developing a validated biomarker for angiogenesis inhibitors: the motesanib experience. by PLOS ONE Staff

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Brain-Specific Angiogenesis Inhibitor 3 Is Expressed in the Cochlea and Is Necessary for Hearing Function in Mice by Chika Saegusa, Wataru Kakegawa, Eriko Miura, Takahiro Aimi, Sachiyo Mogi, Tatsuhiko Harada, Taku Yamashita, Michisuke Yuzaki, Masato Fujioka

“…In this study, we examined the expression and function of brain-specific angiogenesis inhibitor 3 (Bai3), an adhesion G-protein-coupled receptor, in the cochlea. …”
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Immunopathogenetic mechanisms of skin toxic response of antitumor therapy with mul-tikinase of angiogenesis inhibitors by Shatokhina Е.А., Kruglova L.S.

“…As a result of changing the regulatory mechanisms of inhibition of the physiological renewal of epidermis, suppression of angiogenesis and repair when damaged skin there are various skin toxic reactions that are dependent on receptor targets of angiogenesis inhibitors. The study of the mechanisms of adverse events of targeted therapy is an important way of oncoimmunology and dermatology, which will further help to determine the optimal scheme of correction of dermal toxicity and maximize the effectiveness of the antitumor therapy.…”
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Synthesis and biological evaluation of novel N9-heterobivalent β-carbolines as angiogenesis inhibitors by Liang Guo, Qin Ma, Wei Chen, Wenxi Fan, Jie Zhang, Bin Dai

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Arresten, a collagen-derived angiogenesis inhibitor, suppresses invasion of squamous cell carcinoma. by Mari Aikio, Ilkka Alahuhta, Sini Nurmenniemi, Juho Suojanen, Riitta Palovuori, Susanna Teppo, Timo Sorsa, Carlos López-Otín, Taina Pihlajaniemi, Tuula Salo, Ritva Heljasvaara, Pia Nyberg

“…Arresten is an endogenous angiogenesis inhibitor that is derived from the non-collagenous domain of the basement membrane collagen IV α1 chain. …”
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ARTERIAL HYPERTENSION DURING THERAPY OF ONCOLOGICAL DISEASES WITH ANGIOGENESIS INHIBITORS: SERIOUS IMPEDIMENT OR CONTROLLED REACTION? by Zh. D. Kobalava, E. K. Shavarova

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Efficacy and safety of angiogenesis inhibitors in advanced gastric cancer: a systematic review and meta-analysis by Jing Yu, Yue Zhang, Lai-Han Leung, Lian Liu, Fan Yang, Xiaojun Yao

“…In the present study, we aimed to evaluate the efficacy and safety of angiogenesis inhibitors in advanced GC. We searched published randomized controlled trials (RCTs) comparing angiogenesis inhibitors with non-angiogenesis inhibitors for the treatment of GC. …”
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