IPILIMUMAB IN THERAPY OF METASTATIC MELANOMA by I. V. SAMOILENKO, G. Y. KHARKEVICH, L. V. DEMIDOV

Subjects: Get full text

Neoadjuvant ipilimumab (3 mg/kg or 10 mg/kg) and high dose IFN-α2b in locally/regionally advanced melanoma: safety, efficacy and impact on T-cell repertoire by Ahmad Tarhini, Yan Lin, Huang Lin, Zahra Rahman, Priyanka Vallabhaneni, Prateek Mendiratta, James F. Pingpank, Matthew P. Holtzman, Erik C. Yusko, Julie A. Rytlewski, Uma N. M. Rao, Robert L. Ferris, John M. Kirkwood

Subjects: Get full text

Multimarker scores of Th1 and Th2 immune cellular profiles in peripheral blood predict response and immune related toxicity with CTLA4 blockade and IFNα in melanoma by Arjun Khunger, Ghanashyam Sarikonda, Jennifer Tsau, Anil Pahuja, Zeni Alfonso, Jane Gao, Christian Laing, Christine Vaupel, Naveen Dakappagari, Ahmad A. Tarhini

Subjects: Get full text

Encapsulated Checkpoint Blocker Before Chemotherapy: The Optimal Sequence of Anti-CTLA-4 and Doxil Combination Therapy by Alimohammadi R, Alibeigi R, Nikpoor AR, Chalbatani GM, Webster TJ, Jaafari MR, Jalali SA

Subjects: Get full text

The use of immunotherapy in the treatment of melanoma by Tala Achkar, Ahmad A. Tarhini

Subjects: Get full text

Homologous recombination repair gene mutations as a predictive biomarker for immunotherapy in patients with advanced melanoma by Zhixuan You, Meng Lv, Xuanyu He, Yingqin Pan, Junfeng Ge, Xue Hu, Yating Zheng, Mengli Huang, Chengzhi Zhou, Changxuan You

Subjects: Get full text

Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model by Cameron S. Field, Martin K. Hunn, Peter M. Ferguson, Christiane Ruedl, Lindsay R. Ancelet, Ian F. Hermans

Subjects: Get full text

Combination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD-1/PD-L1 therapies by Sonam Puri, Michael Shafique

Subjects: “…anti-ctla-4…”
Get full text

Triple Immunotherapy Overcomes Immune Evasion by Tumor in a Melanoma Mouse Model by Mary-Ann N. Jallad, Abdo R. Jurjus, Elias A. Rahal, Alexander M. Abdelnoor

Subjects: Get full text

Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis by Cayman Williams, Alan Kennedy, Maximillian A. Robinson, Christopher Lloyd, Simon J. Dovedi, David M. Sansom

Subjects: Get full text

Efficacy and toxicity of Ipilimumab-Nivolumab combination therapy in elderly metastatic melanoma patients by Ronen Stoff, Shirly Grynberg, Nethanel Asher, Shachar Laks, Yael Steinberg, Jacob Schachter, Ronnie Shapira-Frommer, Guy Ben-Betzalel

Subjects: Get full text

TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for anti‐CTLA4 treatment by Huahua Li, Jia Li, Chenyue Zhang, Chenxing Zhang, Haiyong Wang

Subjects: “…anti‐CTLA4 treatment…”
Get full text

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st–3rd, 2022—Naples, Italy) by Paolo A. Ascierto, Sanjiv S. Agarwala, Allison Betof Warner, Marc S. Ernstoff, Bernard A. Fox, Thomas F. Gajewski, Jérôme Galon, Claus Garbe, Brian R. Gastman, Jeffrey E. Gershenwald, Pawel Kalinski, Michelle Krogsgaard, Rom S. Leidner, Roger S. Lo, Alexander M. Menzies, Olivier Michielin, Poulikos I. Poulikakos, Jeffrey S. Weber, Corrado Caracò, Iman Osman, Igor Puzanov, Magdalena Thurin

Subjects: Get full text

Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells by Adriana Amaro, Francesco Reggiani, Daniela Fenoglio, Rosaria Gangemi, Anna Tosi, Alessia Parodi, Barbara Banelli, Valentina Rigo, Luca Mastracci, Federica Grillo, Alessandra Cereghetti, Aizhan Tastanova, Adhideb Ghosh, Fabio Sallustio, Laura Emionite, Antonio Daga, Tiziana Altosole, Gilberto Filaci, Antonio Rosato, Mitchell Levesque, Michele Maio, Ulrich Pfeffer, Michela Croce, EPigenetic Immune-oncology Consortium Airc (EPICA) consortium

Subjects: Get full text

Immunotherapy after progression to double immunotherapy: pembrolizumab and lenvatinib versus conventional chemotherapy for patients with metastatic melanoma after failure of PD-1/C... by Georgios Lyrarakis, Michael Liontos, Amalia Anastasopoulou, Spyridon Bouros, Aikaterini Gkoufa, Panagiotis Diamantopoulos, Helen Gogas, Dimitrios C. Ziogas

Subjects: Get full text

The great debate at “Immunotherapy Bridge 2018”, Naples, November 29th, 2018 by Paolo A. Ascierto, Lisa H. Butterfield, Sandra Demaria, Robert L. Ferris, Gordon J. Freeman, Roger S. Lo, Alberto Mantovani, Paul Nathan, Omid Hamid, Katerina Politi, Igor Puzanov

Subjects: “…Anti-CTLA-4…”
Get full text

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd–5th, 2020, Italy) by Paolo A. Ascierto, Christian Blank, Reinhard Dummer, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Patrick Hwu, Pawel Kalinski, Michelle Krogsgaard, Roger S. Lo, Jason J. Luke, Bart Neyns, Michael A. Postow, Sergio A. Quezada, Michele W. L. Teng, Giorgio Trinchieri, Alessandro Testori, Corrado Caracò, Iman Osman, Igor Puzanov, Magdalena Thurin

Subjects: Get full text

Targeting CTLA-4 in Cancer: Biological Insights with a Focus on Renal Cell Carcinoma by Juan Wu, Ya-fei Ren, Jun Xie, Dong-sheng Li

Subjects: Get full text

Combination immune checkpoint blockade as an effective therapy for mesothelioma by Vanessa S. Fear, Caitlin Tilsed, Jonathan Chee, Catherine A. Forbes, Thomas Casey, Jessica N. Solin, Sally M. Lansley, Willem Joost Lesterhuis, Ian M. Dick, Anna K Nowak, Bruce W. Robinson, Richard A. Lake, Scott A. Fisher

Subjects: Get full text

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy) by Paolo A. Ascierto, Sanjiv S. Agarwala, Christian Blank, Corrado Caracò, Richard D. Carvajal, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Jean-Jacques Grob, Omid Hamid, Michelle Krogsgaard, Roger S. Lo, Amanda W. Lund, Gabriele Madonna, Olivier Michielin, Bart Neyns, Iman Osman, Solange Peters, Poulikos I. Poulikakos, Sergio A. Quezada, Bradley Reinfeld, Laurence Zitvogel, Igor Puzanov, Magdalena Thurin

Subjects: Get full text